[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"malocclusion-angle-class-ii\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:malocclusion-angle-class-ii":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,43,68],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":4},"100599024","3d-printed-occlusal-splints-for-intraoperative-use-100599024",false,"NCT07079111","3D Printed Occlusal Splints for Intraoperative Use","Inclusion Criteria:\n\n* Patients of any age who require any orthognathic surgery (including, but not limited to, facial fracture reduction and fixation, mandibular or maxillary reconstruction, cranial vault reconstruction, mandibular osteotomies, maxilla osteotomies) at Johns Hopkins Hospital.\n\nExclusion Criteria:\n\n* Patients who are non-English speaking.\n* Surgeons who do not perform orthognathic surgery with occlusal splints.","ALL","0 Years","80 Years",{"count":19,"type":20},70,"ESTIMATED","INTERVENTIONAL",[23],"NA","A 3D printed intraoperative occlusal splint is a custom-made biocompatible resin guide that allows surgeons properly align a patient's upper and lower dentition during surgery. This alignment further places maxilla and mandible into proper position. An occlusal splint contains outlines maxillary and mandibular dentition allowing the teeth to lock into place with correct alignment.\n\nAt Johns Hopkins, traditionally hand-made and industry-made 3D printed splints have been used safely. However, prior studies have demonstrated the ability of in-house 3D prints to save time and money compared to industry. In-house models are similarly produced with FDA-clear, biocompatible resin for 3D printing, and maintain equivalent safety for patients compared to industry-made models.",[26,27,28],"Malocclusion, Angle Class I","Malocclusion, Angle Class II","Malocclusion, Angle Class III",[30],"malocclusion","NOT_YET_RECRUITING","2026-04-09",{"date":34,"type":35},"2026-04-13","ACTUAL",{"date":37,"type":20},"2026-08-30",{"date":39,"type":20},"2030-08-30",{"name":41,"class":42},"Johns Hopkins University","OTHER",{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":15,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":21,"phases":54,"briefSummary":55,"conditions":56,"keywords":4,"overallStatus":57,"whyStopped":4,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":65,"locationsCount":67},"100512294","treatment-of-skeletal-class-ii-malocclusion-with-modified-twin-block-appliance-with-clear-plates-100512294","NCT05950581","Treatment of Skeletal Class II Malocclusion With Modified Twin-Block Appliance With Clear Plates","Treatment Skeletal Class II Malocclusion With Modified Twin-Block Appliance With Clear Plates VS Traditional Twin Block","Inclusion Criteria:\n\n* \\- Patients with mixed dentition at age 10.5-13 years.\n* The patient has Skeletal class II malocclusion caused by mandibular retraction ANB \\> 5, 8 mm \\>O.J\\> 5 mm, SNB\\\u003C78, angle (NSAr) ≥ ° 125 and normal placement of the upper jaw.\n* The patient is willing to accept treatment with a removable device.\n* No previous orthodontic treatment\n* the growth model is within the normal or horizontal maxillary opening angle of 30 \\>MM or angle of 400 \\> Björk\n* patients do not have an upper alveolar dental protrusion.\n\nExclusion Criteria:\n\n* -Patients with periodontal disease.\n* patients with a neuromuscular disorder.\n* patients of class I or III of malocclusion.\n* Patients with temporomandibular joint disorder.\n* Patients with Skeletal open bite.\n* Patients with poor oral and gingival health\n* the presence of a unilateral or bilateral posterior crossbite.\n* patients who have upper jaw stenosis and need to be prepared by expansion before functional treatment.\n* any patient who does not meet one or more of the Inclusion criteria will be removed from the study.","10 Years","13 Years",{"count":53,"type":20},32,[23],"Patients with skeletal class II malocclusion who have a retracted lower jaw will be treated in this study. The efficacy of clear Plates in the treatment of Skeletal Class II Malocclusion will be assessed. The skeletal, dental and soft tissues changes resulted by this intervention will be studied and compared with the results of Traditional treatment with fixed appliances.",[27],"RECRUITING","2025-09-09",{"date":60,"type":35},"2025-09-15",{"date":62,"type":20},"2026-03-15",{"date":64,"type":20},"2026-09-15",{"name":66,"class":42},"Hama University",1,{"id":69,"slug":70,"hasResults":11,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":4,"eligibilityCriteria":74,"healthyVolunteers":75,"sex":15,"minAge":51,"maxAge":4,"enrollmentInfo":76,"targetDuration":4,"studyType":78,"phases":4,"briefSummary":79,"conditions":80,"keywords":81,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":67},"100504813","therapeutic-effects-of-class-ii-elastics-on-aligners-in-different-vertical-skeletal-patterns-100504813","NCT05853211","Therapeutic Effects of Class II Elastics on Aligners in Different Vertical Skeletal Patterns","Therapeutic Effects of Class II Elastics on Aligners in Different Vertical Skeletal Patterns in Adult Patients: Retrospective Study.","Inclusion Criteria:\n\n* CVM stage 5 on lateral teleradiography (end of growth)\n* Angle Class II\n* Treatments with rubber bands for inter-arch traction\n* End of treatment in class I\n\nExclusion Criteria:\n\n* Incomplete data\n* Treatment with extractions, mini-screws, mini-plate or ortho-surgical treatment\n* Dental agenesis (excluding wisdom teeth)\n* Cranial-facial syndromes",true,{"count":77,"type":20},80,"OBSERVATIONAL","The objective is to compare the dento-alveolar therapeutic effects of wearing class II inter-arch traction elastics on aligners versus multi-brackets in an adult population. The principal hypothesis is no significant difference in therapeutic effects of using inter-arch elastics on aligners versus multi-brackets.",[27],[82,83,84,85,86,87,88,89,90,91],"aligner","inter-arch elastic","orthodontic","class II malocclusion","adult","clear aligner","orthodontic appliance","Invisalign","class II elastics","angle class II malocclusion","2024-07-20",{"date":94,"type":35},"2024-07-23",{"date":96,"type":20},"2024-09-30",{"date":98,"type":20},"2024-10-01",{"name":100,"class":42},"Central Hospital, Nancy, France"]