[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"malocclusion-in-children\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:malocclusion-in-children":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,54],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":36,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":53},"100371514","orthognathic-speech-pathology-phonetic-contrasts-of-patients-with-dental-discrepancies-pre--and-post-treatment-analyses-100371514",false,"NCT04117360","Orthognathic Speech Pathology: Phonetic Contrasts of Patients With Dental Discrepancies Pre- and Post-Treatment Analyses","Orthognathic Speech Pathology: Phonetic Contrasts of Patients With Dentofacial Discrepancies With Pre- and Post-Treatment Analyses","OSP","Inclusion Criteria:\n\n* Jaw surgery patient at UNC with a skeletal open bite, underbite or overjet greater than 5mm.\n* Age 15-40 years\n\nExclusion Criteria:\n\n* Hearing loss\n* Learned English as a second language\n* Significant regional accent, as characterized by a speech pathologist\n* Developmental delay, performing several grade levels below age bracket\n* history of craniofacial disorder\n* genetic syndrome associated with known craniofacial presentation\n* history of craniofacial trauma\n* history of prior craniofacial surgery (excluding extractions and dental procedures)\n* Jaw surgery without fixed orthodontic appliances","ALL","15 Years","40 Years",{"count":21,"type":22},180,"ESTIMATED","OBSERVATIONAL","The investigators are studying how speech is effected by jaw and tooth position in jaw surgery patients. Eighty percent of our jaw surgery patients have speech pathologies, compared to five percent of the general population, but speech pathologists do not understand why. The investigators hypothesize that open bites and underbites prevent most patients from being able to pronounce words normally and surgical correction will lead to improvement in speech. Patients will be audio recorded speaking and patients' tongue gestures ultrasound recorded before and after their jaw surgeries to observe what changes occur in their speech and tongue movements.",[26,27,28,29,30,31,32,33,34,35],"Dentofacial Abnormalities","Dentofacial Deformities","Dentofacial Anomalies, Including Malocclusion","Malocclusion","Malocclusion in Children","Dentofacial Disharmony","Skeletal Malocclusion","Skeletal Malformation","Speech Sound Disorder","Speech Disorders",[31,37,34,38,39,40],"Skeletal malocclusion","Spectral Moment Analysis","Tongue Ultrasound","Orthognathic Surgery","RECRUITING","2026-06-10",{"date":44,"type":45},"2026-06-12","ACTUAL",{"date":47,"type":45},"2019-09-11",{"date":49,"type":22},"2028-03",{"name":51,"class":52},"University of North Carolina, Chapel Hill","OTHER",1,{"id":55,"slug":56,"hasResults":11,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":60,"eligibilityCriteria":61,"healthyVolunteers":11,"sex":17,"minAge":62,"maxAge":18,"enrollmentInfo":63,"targetDuration":65,"studyType":23,"phases":4,"briefSummary":66,"conditions":67,"keywords":4,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":53},"100556246","3d-analysis-of-palatal-morphology-of-growing-patients-treated-with-rapid-palatal-expander-100556246","NCT06522607","3D Analysis of Palatal Morphology of Growing Patients Treated With Rapid Palatal Expander.","Three-dimensional Analysis of Palatal Morphology of Hypo-, Hyper-, Normodivergent Growing Subjects With Posterior Cross-bite Treated With Rapid Palatal Expander, a Longitudinal Pilot Study.","3D_MoPal","Inclusion Criteria:\n\n* Caucasian origin;\n* Mixed dentition stage;\n* Angle class I or straight step or mesial step molar relationship in primary dentition;\n* Skeletal class I (ANB angle between 0° and 5°);\n* Vertical dimension evaluated on lateral cephalograms: SN\\^GoGn\\>37°: hyperdivergent, SN\\^GoGn\\\u003C27°: hypodivergent, 27°\\\u003CSN\\^GoGn\\>37°: normodivergent;\n* Cervical vertebral stage 1 or 2 (CVS methods 1-2);\n* Posterior cross-bite including deciduous or permanent teeth;\n* Presence of good quality pre-treatment records (history, intraoral and extraoral photographs, oral scan, panoramic radiographs, and lateral cephalometric radiographs with reference ruler);\n* Oral scan and photographs available for each subject 6 months after the beginning of the therapy;\n* Signing the informed consent form.\n\nExclusion Criteria:\n\n* Previous orthodontic treatment;\n* Tooth agenesis or supernumerary teeth;\n* Craniofacial abnormalities;\n* Tooth impaction in the maxilla;\n* Torus palatinus;\n* History of dental trauma (avulsion and alveolar\u002Fjaw fracture);\n* Refusal to sign consent form.","7 Years",{"count":64,"type":22},36,"6 Months","The aim of the present study is to assess the changes of palatal morphology among growing patients with different vertical facial growth patterns treated with rapid palatal expander.\n\nThirty-six patients referred to \"Policlinico Agostino Gemelli\" university hospital will be selected. The eligible criteria are posterior cross-bite, mixed dentition, skeletal Class I relationship and prepubertal stage of cervical vertebral maturation. The patients will be split into three groups according to facial divergency (hyper-, hypo-, normodivergent subjects). For each subject, digital dental casts will be recorded before and after treatment using an intraoral scanner. To evaluate two-dimensional maxillary arch changes, linear measurements will be done. To study comprehensively the palatal shape, a set of 240 landmark and semi-landmarks will be digitized on the palatal vault. Then, Geometric Morphometric Analysis (GMA) will be performed to compare morphological variations of the palate among different vertical facial growth pattern groups.",[68,30],"Cross-bite","2025-08-26",{"date":71,"type":45},"2025-09-03",{"date":73,"type":45},"2024-07-17",{"date":75,"type":22},"2026-12-31",{"name":77,"class":52},"Fondazione Policlinico Universitario Agostino Gemelli IRCCS"]