[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"mammography\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:mammography":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,52,79,106,129],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100632279","a-multi-level-strategy-for-de-implementing-mammography-overuse-among-older-women-100632279",false,"NCT07511621","A Multi-Level Strategy for De-implementing Mammography Overuse Among Older Women","De-implementation of Overuse of Mammography Screening in Older Racially and Ethnically Diverse Women","Patient level criteria\n\nInclusion criteria\n\n* English- or Spanish-speaking women based on preferred language in electronic health record\n* Aged 75 and older at the time of their scheduled primary care visit\n* Women who have a primary care visit scheduled within the next 2-4 weeks\n* Women who have not had a screening mammogram 6 months prior to their scheduled primary care visit but have had a screening mammogram 7-18 months prior to their scheduled primary care visit\n\nExclusion Criteria\n\n* Women with a history of atypical ductal hyperplasia (ADH) or non-invasive or invasive breast cancer (assessed via ICD 10 code)\n* Women with dementia (assessed via ICD 10 code)\n* ICD codes to use across exclusion criteria: F01-F03, Z85.3, G30-G31, N60, C50, or D05\n\nProvider level criteria\n\nInclusion Criteria\n\n• Primary care clinicians attributed to the 2 intervention clinics that serve adult patients, including those ≥75 years\n\nExclusion Criteria\n\n* Specialists\n* Primary care clinicians for patients \\\u003C 18 years old\n* Non-clinicians\n* Physician assistants",true,"ALL","18 Years",{"count":20,"type":21},500,"ESTIMATED","INTERVENTIONAL",[24],"NA","This project aims to advance methodological and theoretical approaches for developing, selecting, refining, and piloting a multilevel de-implementation strategy to reduce the overuse of screening mammography in women aged ≥75 years. Informed by an innovative participatory, stakeholder-driven innovation tournament and a discrete choice experiment, the research team identified, prioritized, and tailored a multilevel de-implementation strategy. The research team will conduct a cluster randomized controlled trial (at the provider level) to test the impact of the provider- and patient-level components of the multilevel strategy on screening mammography use, and secondarily, on provider referrals\u002Forders for screening mammography. The organizational level components of the multilevel strategy will be implemented among all participants, not via random assignment.",[27,28,29,30],"Mammography","Medical Overuse","Evidence-based Practice","Older Adults",[27,32,33,34,35,36,37,38],"Medical overuse","Implementation science","Aging","Women","Randomized controlled trial","Screening cessation","De-implementation","RECRUITING","2026-03-30",{"date":42,"type":43},"2026-04-06","ACTUAL",{"date":45,"type":43},"2026-03-11",{"date":47,"type":21},"2028-03",{"name":49,"class":50},"Columbia University","OTHER",1,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":4,"studyType":22,"phases":64,"briefSummary":65,"conditions":66,"keywords":67,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":51},"100622847","pilot-study-of-mammogrip-for-breast-positioning-image-quality-and-patient-comfort-in-mammography-100622847","NCT07388940","Pilot Study of MammoGRIP for Breast Positioning, Image Quality, and Patient Comfort in Mammography","MammoGRIP","Inclusion Criteria:\n\n* Women aged 40-75 years undergoing routine screening or diagnostic mammography\n* Ability to provide informed consent\n* Prior mammogram results are available for the patient in Epic\n\nExclusion Criteria:\n\n* History of bilateral mastectomy\n* Active skin condition or open wounds on the breast or chest\n* Known allergy to components of MammoGRIP®","FEMALE","40 Years","75 Years",{"count":63,"type":21},50,[24],"To evaluate the effectiveness of MammoGRIP® in improving mammographic image quality and minimizing repeated breast positioning compared to standard practice without MammoGRIP®.",[27],[68],"Mammogram","NOT_YET_RECRUITING","2026-01-28",{"date":72,"type":43},"2026-02-05",{"date":74,"type":21},"2026-02",{"date":76,"type":21},"2027-02",{"name":78,"class":50},"Englewood Hospital and Medical Center",{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":4,"eligibilityCriteria":85,"healthyVolunteers":11,"sex":59,"minAge":86,"maxAge":87,"enrollmentInfo":88,"targetDuration":4,"studyType":90,"phases":4,"briefSummary":91,"conditions":92,"keywords":93,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":51},"100570951","diagnostic-performance-of-contrast-enhanced-mammography-100570951","NCT06713915","Diagnostic Performance of Contrast-Enhanced Mammography","Diagnostic Performance of Contrast-Enhanced Mammography in Suspicious Breast Lesions","Inclusion Criteria:\n\n* Breast ultrasound or\u002Fand general mammography suggest that the lesion is BI-RADS 4 or above;\n* Willing to undergo enhanced mammography examination;\n* Agree to perform tumor core needle biopsy or excisional biopsy to confirm pathological diagnosis when necessary.\n\nExclusion Criteria:\n\n* Allergy to iodinated contrast;\n* Pregnant and lactating women;\n* Suffering from kidney disease or abnormal kidney function, or undergoing renal dialysis;\n* The breast is too large to be completely included in the full-field mammography examination at one time; ○5 Those with breast implants.","30 Years","80 Years",{"count":89,"type":21},600,"OBSERVATIONAL","Contrast-Enhanced Mammography (CEM) is a functional breast imaging technology. Like magnetic resonance imaging (MRI), CEM neovascularization enhancement can improve cancer detection rates, while lack of enhancement may lead to benign determination. The advantages of CEM are dramatically apparent in women with dense breasts. The purpose of this study was to investigate the additional diagnostic value of CEM added to the standard practice of mammography plus ultrasonography(US) in patients with suspicious breast lesions.\n\nThis study was a single-center prospective-retrospective combined observational study. In the prospective part, women with suspected breast abnormalities undergo prospective CEM evaluation, including acquisition of low energy (LE) images and recombined images (RI) showing enhancement, concurrently with breast US. The retrospective part selected the mammography and breast US data of female patients with suspected breast abnormalities who had previous baseline matching.",[27],[94,95,96],"breast cancer","breast ultrasound","contrast enhanced mammography","2024-11-27",{"date":99,"type":43},"2024-12-03",{"date":101,"type":21},"2025-01",{"date":103,"type":21},"2027-12",{"name":105,"class":50},"ZHOU Yidong",{"id":107,"slug":108,"hasResults":11,"nctId":109,"briefTitle":110,"officialTitle":111,"acronym":112,"eligibilityCriteria":113,"healthyVolunteers":11,"sex":59,"minAge":18,"maxAge":4,"enrollmentInfo":114,"targetDuration":4,"studyType":22,"phases":116,"briefSummary":117,"conditions":118,"keywords":4,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":121,"lastUpdatePostDateStruct":122,"startDateStruct":124,"completionDateStruct":125,"leadSponsor":127,"locationsCount":4},"100552170","study-on-female-patients-mammographic-texture-features-100552170","NCT06469606","Study on Female Patients' Mammographic Texture Features","A Cohort Study on feMale Patients' mammogRaphic texturE featureS: the COMPRESS Trial","COMPRESS","Inclusion Criteria:\n\n* Candidate is a biological female aged 18 years or above;\n* Candidate is willing and able to give informed consent and gives their written consent for the participation in the study;\n* There is a clinical indication for a uni- or bilateral mastectomy\n\nExclusion Criteria:\n\n* Candidate lacks the capacity to provide informed consent;\n* Candidate has breast implants",{"count":115,"type":21},200,[24],"Mammography is the most common method for breast imaging, and it provides information for model building and analysis. Radiomics applied to mammography has the potential to revolutionize clinical decision-making by providing valuable insights into risk assessment and disease detection. Despite this, the influence of imaging parameters and clinical and biological factors on radiological texture features remains poorly understood. There is a pressing need to overcome the obstacle of system-inherent effects on mammographic images to facilitate the translation of radiological texture features into routine clinical practice by enabling reliable and robust AI-based or AI-aided decision-making. Furthermore, understanding the relationship between imaging parameters, textural features, and clinical and biological information supports the clinical use of AI. The objective of this study is to evaluate AI methods for clinical practice and to study how it relates to clinical factors and biological features.",[119,120,27],"Breast Cancer","Artificial Intelligence","2024-06-17",{"date":123,"type":43},"2024-06-21",{"date":121,"type":21},{"date":126,"type":21},"2038-12-15",{"name":128,"class":50},"Tampere University Hospital",{"id":130,"slug":131,"hasResults":11,"nctId":132,"briefTitle":133,"officialTitle":134,"acronym":135,"eligibilityCriteria":136,"healthyVolunteers":16,"sex":59,"minAge":60,"maxAge":137,"enrollmentInfo":138,"targetDuration":4,"studyType":22,"phases":140,"briefSummary":141,"conditions":142,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":144,"lastUpdatePostDateStruct":145,"startDateStruct":147,"completionDateStruct":149,"leadSponsor":151,"locationsCount":51},"100431949","contrast-enhanced-spectral-mammography-cesm-breast-cancer-screening-100431949","NCT04904757","Contrast-enhanced Spectral Mammography (CESM) Breast Cancer Screening","Willingness of Women to Undergo a Contrast-enhanced Spectral Mammography (CESM) for Breast Cancer Screening and Their Experience Before and After CESM","S-CESM","Inclusion Criteria:\n\n* • Female\n\n  * 40 to 69 years\n  * Previous normal mammogram (BI-RADS 1 or 2) showing heterogeneous or extremely dense breast tissue within last 24 months\n  * Scheduled for screening mammogram as part of the patient's clinical care\n\nExclusion Criteria:\n\n* • No mammogram within last 24 months\n\n  * Fatty or scattered fibroglandular tissue on last mammogram\n  * History of allergy to iodinated contrast\n  * History of renal disease or renal function abnormalities\n  * Pregnant women\n  * History of diabetes\n  * History of paraproteinemia syndromes such as multiple myeloma\n  * History of collagen vascular disease\n  * History of vascular disease (coronary artery disease, myocardial infarction, carotid disease, peripheral vascular disease, or known visceral artery disease)\n  * Previously identified as high risk for breast cancer (\\>20% lifetime risk)\n  * Asthma\n  * Sickle Cell Anemia\n  * Currently on Dialysis","69 Years",{"count":139,"type":21},210,[24],"The purpose of this study is to evaluate how well women may adopt a Contrast-enhanced Spectral Mammography (CESM) as their yearly breast screening test compared to the standard 2-D or 3-D mammogram.",[143,27],"Mammographic Breast Density","2022-11-16",{"date":146,"type":43},"2022-11-17",{"date":148,"type":43},"2019-09-19",{"date":150,"type":21},"2023-06",{"name":152,"class":50},"University of Virginia"]