[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"masticatory-performance\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:masticatory-performance":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,44],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":4},"100640792","evaluation-of-occlusal-force-and-masticatory-function-in-children-with-molar-incisor-hypomineralization-100640792",false,"NCT07589179","Evaluation of Occlusal Force and Masticatory Function in Children With Molar-Incisor Hypomineralization","Evaluation of Occlusal Force Distribution and Masticatory Function Before and After Restorative Treatment in Children With Molar-Incisor Hypomineralization","Inclusion Criteria:\n\n* Children aged 7 to 12 years\n* Presence of bilateral molar-incisor hypomineralization (MIH) affecting first permanent molars\n* Need for restorative treatment in MIH-affected molars\n* Cooperative children with sufficient cognitive ability to complete functional assessments\n* Presence of healthy control participants without MIH for comparison\n* Mixed dentition period\n* Signed informed consent obtained from parents or legal guardians\n\nExclusion Criteria:\n\n* Temporomandibular disorders or orofacial pain\n* Systemic diseases or regular medication use affecting mastication\n* History of orthodontic treatment or parafunctional habits\n* Craniofacial anomalies or developmental dental anomalies\n* Extensive prosthetic restorations affecting chewing function\n* Uncooperative children unable to complete examination procedures\n* Acute dental infection or pain requiring emergency treatment",true,"ALL","7 Years","13 Years",{"count":21,"type":22},68,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study aims to evaluate right-left chewing balance and masticatory function in children with Molar-Incisor Hypomineralization (MIH) before and after restorative treatment. MIH is a developmental enamel defect that may cause tooth sensitivity, discomfort during chewing, and functional asymmetry.\n\nChildren aged 7 to 12 years with bilateral MIH affecting the first permanent molars will receive glass hybrid restorative treatment. Right-left occlusal force distribution will be assessed using a digital occlusal analysis system. In addition, chewing side preference and chewing balance will be evaluated using a standardized chewing gum protocol. These two assessment methods will be used together to provide complementary information about masticatory function.\n\nMeasurements will be performed before treatment and during follow-up visits after treatment. The findings obtained from children with MIH will also be compared with healthy children without MIH. The study aims to determine whether restorative treatment improves chewing balance and functional oral performance in children with MIH.",[28,29,30,31],"Molar-Incisor Hypomineralization (MIH)","Masticatory Performance","Occlusal Analysis","Chewing Function","NOT_YET_RECRUITING","2026-06-02",{"date":35,"type":36},"2026-06-04","ACTUAL",{"date":38,"type":22},"2026-05-11",{"date":40,"type":22},"2026-12-20",{"name":42,"class":43},"Marmara University","OTHER",{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":17,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":56,"studyType":57,"phases":4,"briefSummary":58,"conditions":59,"keywords":60,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":5},"100560781","masticatory-performance-evaluation-100560781","NCT06581614","Masticatory Performance Evaluation","Effect of Implant Supported Fixed Restoration on Masticatory Efficiency in Patients With Second Molar Loss","MPE","For prospective group:\n\nInclusion Criteria:\n\n* Patients who have lost their second molar, are scheduled to undergo single-implant reconstruction at the Prosthodontics Department of National Taiwan University Hospital, and do not have any major physical or mental health conditions.\n\nExclusion Criteria:\n\n* Severe temporomandibular joint disorder\n* Inability to comply with the treatment schedule\n* Inability to cooperate with masticatory function tests\n* Lack of opposing teeth for the implant-supported restoration\n* Patients whose anterior teeth will be included in the prosthetic reconstruction or whose occlusion will undergo significant changes after reconstruction\n\nFor retrospective group:\n\nInclusion Criteria:\n\n* Patients who have lost their second molar, have undergone single-implant-supported fixed restoration reconstruction at the Prosthodontics Department of National Taiwan University Hospital, and do not have any major physical or mental health conditions.\n\nExclusion Criteria:\n\n* Implant-supported dentures that cannot be removed or have significant damage\n* Severe temporomandibular joint disorder\n* Inability to comply with the treatment schedule\n* Inability to cooperate with masticatory function tests\n* Lack of opposing teeth for the implant-supported denture","25 Years","85 Years",{"count":55,"type":22},60,"1 Year","OBSERVATIONAL","The purpose of this experiment is to combine research on masticatory efficiency with the reconstructive expertise of the prosthodontics clinic, focusing on implant-supported fixed dentures as the contemporary gold standard for reconstruction. The goal is to investigate the impact of such prosthetic reconstructions on masticatory efficiency. We will invite patients who have lost their second molar and have undergone single-implant-supported fixed denture reconstruction at the Prosthodontics Department of National Taiwan University Hospital to participate in masticatory function tests. The tests will use a new and relatively simple chewing gum, with the aim of enhancing patients\\' masticatory function through implant reconstruction in a clinical setting, thereby improving patient well-being and understanding of dental implants. On the research side, the study aims to provide guidance for strategies in the reconstruction of masticatory function.",[29],[61,62,63],"implant supported fixed prosthesis","masticatory efficiency","chewing gum","RECRUITING","2025-11-16",{"date":67,"type":36},"2025-11-18",{"date":69,"type":36},"2024-08-31",{"date":71,"type":22},"2027-08-31",{"name":73,"class":43},"National Taiwan University Hospital"]