[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"maxillary-expansion\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:maxillary-expansion":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,50,76,100,123],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100631401","quad-helix-vs-rme-for-posterior-cross-bite-in-egyptian-children-100631401",false,"NCT07500194","Quad Helix vs RME for Posterior Cross-bite in Egyptian Children","Quad Helix Versus Rapid Maxillary Expanders in the Treatment of Posterior Cross-bite During Mixed Dentition in a Sample of Egyptian Children: A Randomized Clinical Study.","Expansion","Inclusion Criteria:\n\n1. Children aged 9-12 years in the mixed dentition stage\n2. Presence of posterior cross-bite due to transverse maxillary deficiency\n3. No previous history of orthodontic treatment\n4. Good oral hygiene and cooperative behavior\n5. No significant antero-posterior or vertical skeletal discrepancies\n\nExclusion Criteria:\n\n1. Patient with craniofacial anomalies\n2. Presence of systemic diseases or syndromes affecting bone metabolism\n3. Extensive dental caries or untreated periodontal disease\n4. History of trauma or surgery affecting the maxilla or mandible","ALL","9 Years","12 Years",{"count":21,"type":22},20,"ESTIMATED","INTERVENTIONAL",[25],"NA","This randomized clinical trial aims to evaluate and compare the effectiveness of the Quad Helix (QH) appliance versus Rapid Maxillary Expanders (RME) in treating posterior cross-bite in Egyptian children during the mixed dentition stage. The study will also assess patient comfort and pain levels associated with each appliance.",[28,29,30],"Posterior Crossbite","Maxillary Expansion","Transverse Maxillary Deficiency",[32,33,34,35,36,37],"Quad Helix","Rapid Maxillary Expansion","Posterior cross-bite","Mixed Dentition","Egyptian children","Randomized clinical trials","NOT_YET_RECRUITING","2026-03-24",{"date":41,"type":42},"2026-03-30","ACTUAL",{"date":41,"type":22},{"date":45,"type":22},"2028-03-31",{"name":47,"class":48},"Al-Azhar University","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":57,"sex":17,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":4,"studyType":23,"phases":62,"briefSummary":63,"conditions":64,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":75},"100496353","3d-printed-versus-laboratory-fabricated-hyrax-expanders-100496353","NCT05743127","3D-Printed Versus Laboratory-Fabricated Hyrax Expanders","3D-Printed Versus Laboratory-Fabricated Hyrax Expanders: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Maxillary anterior and\u002For posterior transverse deficiency with or without crossbite\n* Age of 8-13 years\n* Children whose parents\u002Fguardians are willing to consent to the child participating in the study\n* Children ages 12-13 who are willing to assent to participating in the study\n* Children who are orthodontic patients at the Medical University of South Carolina Department of Orthodontics or University of Pittsburgh School of Dental Medicine\n* Subjects and parents\u002Fguardians who have access to an electronic device with internet connection\n\nExclusion Criteria:\n\n* Patients with previous or ongoing orthodontic treatment\n* Patients whose parents have a strong preference as to which expander is used\n* Patients with a history of temporomandibular disorders\n* Presence of congenitally missing teeth\n* Traumatic loss of maxillary incisors\n* Patients with craniofacial syndromes, or cleft lip and\u002For palate",true,"8 Years","13 Years",{"count":61,"type":22},42,[25],"Maxillary expanders are orthodontic appliances that are commonly used to expand the upper jaw. The purpose of this study will be to compare the effects produced by two different maxillary expanders in children 8-13 years old. The first type of expander is made by hand in an orthodontic laboratory, and the second type of expander is designed on a computer and printed using 3D printers. Both expanders are already used in the MUSC Orthodontics Clinic. The purpose of this study is to see if the 3D printed expander is as effective as the traditional expander made by hand in the laboratory, with more comfort to the patient. Patients participating in the study will be randomly assigned to one of two groups: group A will be treated with a laboratory-made maxillary expander, and group B with a 3D-Printed maxillary expander. Information will be collected on the participants' standard clinical follow-up visits including photos, x-rays, and dental photo scans over the course of 6 months to see how the expander is working. In addition, as part of the research study, the participant will be asked to complete online questionnaires with assistance from parents or guardians about his\u002Fher quality of life and perception of possible pain and discomfort at different time points. The potential benefits of this study include the use of 3D technology to improve the quality of the orthodontic treatment, with more comfort to the patient.",[29],"RECRUITING","2026-03-18",{"date":68,"type":42},"2026-03-20",{"date":70,"type":42},"2023-02-15",{"date":72,"type":22},"2027-05-01",{"name":74,"class":48},"Ildeu Andrade Jr.",2,{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":4,"eligibilityCriteria":82,"healthyVolunteers":57,"sex":17,"minAge":19,"maxAge":83,"enrollmentInfo":84,"targetDuration":4,"studyType":23,"phases":86,"briefSummary":87,"conditions":88,"keywords":89,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":49},"100624550","three-dimensionally-printed-hyrax-versus-conventional-hyrax-for-maxillary-arch-expansion-in-adolescents-100624550","NCT07411092","Three-dimensionally Printed Hyrax Versus Conventional Hyrax for Maxillary Arch Expansion in Adolescents","Three-dimensionally Printed Hyrax Versus Conventional Hyrax for Maxillary Arch Expansion in Adolescents: A Randomized Controlled Trial","Inclusion Criteria:\n\n1. Patients aged between 12 to 17 years.\n2. Skeletal age ranges from CVMS 3 to CVMS 5.\n3. Skeletal maxillary transverse deficiency with\u002Fwithout crossbite.\n4. Cooperative and able to attend follow-up visits.\n\nExclusion Criteria:\n\n1. Previous orthodontic treatment.\n2. Craniofacial syndromes, or cleft lip and\u002For palate.\n3. Patients with vertical growth pattern.\n4. Very bad oral hygiene and active periodontal disease.\n5. Vulnerable groups such as individuals with cognitive impairments or intellectual disabilities and individuals with severe mental health disorders.","17 Years",{"count":85,"type":22},22,[25],"This clinical trial aims to compare the skeletal and dental effects of conventional Hyrax expanders and 3D-printed Hyrax expanders in adolescent patients with maxillary transverse deficiency. Using cone-beam computed tomography (CBCT) and digital models, the study evaluates the precision, customization, and treatment outcomes of both appliance types to inform evidence-based orthodontic treatment planning.",[30,29],[29,90],"Hyrax expander","2026-02-08",{"date":93,"type":42},"2026-02-13",{"date":95,"type":42},"2025-08-01",{"date":97,"type":22},"2027-01-01",{"name":99,"class":48},"Ain Shams University",{"id":101,"slug":102,"hasResults":11,"nctId":103,"briefTitle":104,"officialTitle":105,"acronym":4,"eligibilityCriteria":106,"healthyVolunteers":11,"sex":17,"minAge":107,"maxAge":4,"enrollmentInfo":108,"targetDuration":4,"studyType":23,"phases":110,"briefSummary":111,"conditions":112,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":49},"100618032","evaluation-of-maxillary-expansion-methods-on-nasomaxillary-structures-100618032","NCT07326345","Evaluation of Maxillary Expansion Methods on Nasomaxillary Structures","Evaluation of the Effects of Different Rapid Maxillary Expansion Methods on the Nasomaxillary Complex Structures","Inclusion Criteria:\n\n* Diagnosis of maxillary transverse deficiency.\n* Patients aged 15 years and older.\n* Presence of unilateral or bilateral crossbite.\n\nExclusion Criteria:\n\n* Severe facial deformities or craniofacial syndromes.\n* History of previous orthodontic treatment.\n* Existing pathology or history of surgery related to the paranasal sinuses, nasolacrimal system, or orbital cavity.\n* Inadequate patient cooperation.\n* History of trauma, or previous maxillofacial\u002Fplastic surgery procedures.\n* Clinical signs or symptoms of maxillary sinus pathology (e.g., maxillary sinus cysts, sinusitis).","15 Years",{"count":109,"type":22},30,[25],"Maxillary transverse deficiency is an orthodontic anomaly characterized by the upper and lower dental arches being incompatible due to insufficient width of the maxilla. This condition typically manifests with clinical symptoms such as crossbite, crowding of teeth, and impaired respiratory function. Genetic factors, early primary tooth loss, mouth breathing, thumb sucking, and abnormal swallowing are among the causes of maxillary narrowing. Treatment options vary depending on the patient's age and the degree of suture closure. In pediatric and adolescent patients, rapid (RPE) or slow (SPE) orthodontic expansion can be achieved with palatal expansion appliances. However, in adult patients, due to the less flexible bone structure of the maxilla, methods such as surgically assisted expansion (SARME) or mini-screw-assisted expansion (MARPE) are preferred. Recent studies have shown that MARPE can be effective as a non-surgical alternative in young adults and can provide direct skeletal expansion without damaging the teeth.",[29,113],"Maxillary Transverse Deficiency","2026-01-02",{"date":116,"type":42},"2026-01-08",{"date":118,"type":42},"2025-09-29",{"date":120,"type":22},"2026-05",{"name":122,"class":48},"Merve Kulaksız",{"id":124,"slug":125,"hasResults":11,"nctId":126,"briefTitle":127,"officialTitle":128,"acronym":4,"eligibilityCriteria":129,"healthyVolunteers":11,"sex":17,"minAge":19,"maxAge":130,"enrollmentInfo":131,"targetDuration":4,"studyType":23,"phases":133,"briefSummary":134,"conditions":135,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":136,"lastUpdatePostDateStruct":137,"startDateStruct":139,"completionDateStruct":141,"leadSponsor":143,"locationsCount":4},"100595774","effects-of-skeletal-anchored-maxillary-expander-for-constricted-maxilla-100595774","NCT07036822","Effects of Skeletal Anchored Maxillary Expander for Constricted Maxilla","Effects of Skeletal Anchored Maxillary Expander for Constricted Maxilla With Different Patient's Age (Cone Beam Computed Tomography Study)","Inclusion Criteria:\n\n* Skeletal maxillary transverse deficiency.\n* Unilateral or bilateral posterior crossbite. .Patient maintains good oral hygiene and overall health.\n* Patient with no previous orthodontic treatment.\n* No systemic disease that may affect bone quality or interfere with orthodontic treatment.\n* Adolescent and adult patien\n\nExclusion Criteria:\n\n* Craniofacial congenital disorders, including cleft lip and palate.\n* History of periodontal disease","25 Years",{"count":132,"type":22},24,[25],"The aim of study will be Evaluation of Effects of skeletal anchored maxillary expander for constricted maxilla with different patient's age",[29],"2025-06-24",{"date":138,"type":42},"2025-06-27",{"date":140,"type":22},"2025-09-01",{"date":142,"type":22},"2027-12-01",{"name":144,"class":48},"Samar Hassan Mahmoud Mohamed"]