[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"mechanical-thrombectomy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:mechanical-thrombectomy":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,42,67],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100413541","intra-arterial-neuroprotective-strategy-for-ischemic-stroke-patients-with-endovascular-therapy-insist-et-100413541",false,"NCT04664933","Intra-arterial Neuroprotective Strategy for Ischemic STroke Patients With Endovascular Therapy (INSIST-ET)","Intra-arterial Neuroprotective Strategy for Ischemic STroke Patients With Endovascular Therapy (INSIST-ET): One Single Center, Safety and Feasibility Study","Inclusion Criteria:\n\n1. Age ≥18 years;\n2. Acute ischemic stroke patients who is eligible for endovascular treatment;\n3. Signed informed consent.\n\nExclusion Criteria:\n\n1. Modified Rankin Score \\>2 caused by a history of prior stroke;\n2. Coagulation disorders, systematic hemorrhagic tendency, thrombocytopenia (\\\u003C80000\u002Fmm3);\n3. Severe hepatic or renal dysfunction, increase in ALT or AST (more than 2 times of upper limit of normal value), increase in serum creatinine (more than 1.5 times of upper limit of normal value) or requiring dialysis;\n4. Severe hypertension (systolic blood pressure over 200mmHg or diastolic blood pressure over 110 mmHg);\n5. Unsuitable for this clinical studies assessed by researcher.","ALL","18 Years",{"count":19,"type":20},30,"ESTIMATED","INTERVENTIONAL",[23],"NA","To explore the safety and feasibility of intra-arterial neuroprotective strategy in acute ischemic stroke patients who received recanalization operation.",[26,27,28],"Stroke, Ischemic","Intravascular Thrombosis","Mechanical Thrombectomy","RECRUITING","2025-08-20",{"date":32,"type":33},"2025-08-21","ACTUAL",{"date":35,"type":33},"2020-12-01",{"date":37,"type":20},"2026-05-31",{"name":39,"class":40},"Hui-Sheng Chen","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":21,"phases":52,"briefSummary":54,"conditions":55,"keywords":4,"overallStatus":57,"whyStopped":4,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":65,"locationsCount":41},"100509381","phase-4-high-dose-atorvastatin-for-vascular-wall-protection-in-thrombectomy-patients-100509381","NCT05912686","High-Dose Atorvastatin for Vascular Wall Protection in Thrombectomy Patients","High Dose of Atorvastatin for Preventing Cerebral Vascular Wall Damage in Patients Undergoing Mechanical Thrombectomy","Inclusion Criteria:\n\n1. Clinical diagnosis of acute ischemic stroke;\n2. With anterior circulation acute stroke who meet and receive emergency endovascular treatment;\n3. CTA or DSA confirms anterior circulation intracranial arterial lesions, including MT of intracranial arteries (middle cerebral artery (MCA), internal carotid artery (ICA), basilar artery and\u002For vertebral artery and P1 segment of posterior cerebral artery (PCA);\n4. Recanalization of blood vessels after operation (mTICI ≥ 2b grade)\n\nExclusion Criteria:\n\n1. Placing permanent stents or other implants in the target artery\n2. Can not receive HR-VWI examination of 3T MRI due to claustrophobia or unstable condition\n3. Contraindications to MRI and\u002For intravenous gadolinium","80 Years",{"count":51,"type":20},162,[53],"PHASE4","This project investigates the impact of statins on cerebral vascular wall damage after mechanical thrombectomy. The investigators will undertake a multi-center, prospective, parallel-controlled, open-label, superiority randomized controlled study based on past research on intense lipid-lowering intervention trials. Patients undergoing post-thrombectomy will be divided into two groups: the test group and the control group. After surgery, the test group will be given a high dose of atorvastatin (80mg\u002Fday), followed by a standard dose (20mg\u002Fday). The control group will continue to receive the standard dose of atorvastatin (20mg\u002Fday). The investigators will compare the high-resolution vascular wall MRI characteristics (vascular wall enhancement, lumen stenosis rate, and so on) within 3-5 days of the operation, as well as the composite incidence of ischemic stroke, transient ischemic attack, intracranial hemorrhage 1 month postoperatively, and the modified Rankin Score at 90 days.",[28,56],"Acute Ischemic Stroke","NOT_YET_RECRUITING","2023-06-21",{"date":60,"type":33},"2023-06-23",{"date":62,"type":20},"2023-07-01",{"date":64,"type":20},"2026-07-31",{"name":66,"class":40},"Zhongda Hospital",{"id":68,"slug":69,"hasResults":11,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":73,"eligibilityCriteria":74,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":75,"enrollmentInfo":76,"targetDuration":4,"studyType":21,"phases":78,"briefSummary":79,"conditions":80,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":41},"100482365","efficacy-and-safety-of-head-acupuncture-after-mechanical-thrombectomy-for-acute-ischemic-stroke-100482365","NCT05561088","Efficacy and Safety of Head Acupuncture After Mechanical Thrombectomy for Acute Ischemic Stroke","A Single-center, Prospective, Randomized, Controlled Study of Mechanical Thrombectomy Followed by Acupuncture for Acute Ischemic Stroke","HEALTH","Inclusion Criteria:\n\n* Age ≥18 years;\n* Patients with acute ischemic stroke who received endovascular treatment within 24 hours of onset;\n* 6 \\\u003C NIHSS ≤25;\n* ASPECT score ≥6 points;\n* Signed Informed consent.\n\nExclusion Criteria:\n\n* CT or brain MRI confirmed intracranial tumor and intracranial hemorrhage;\n* Contraindications of contrast media;\n* Dementia or mental illness，unable to cooperate with treatment and follow-up;\n* The expected survival time was less than 3 months;\n* Women who are pregnant, planning to become pregnant or breastfeeding;\n* Currently participating in other clinical trials.","100 Years",{"count":77,"type":20},272,[23],"To evaluate the efficacy and safety of head acupuncture combined with endovascular therapy for cerebral infarction compared with endovascular therapy alone",[81,56,28],"Acupuncture","2023-05-11",{"date":84,"type":33},"2023-05-12",{"date":86,"type":33},"2023-04-27",{"date":88,"type":20},"2028-10-31",{"name":90,"class":91},"Xi'an No.3 Hospital","OTHER_GOV"]