[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"median-nerve-compression\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:median-nerve-compression":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,51,84],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":4},"100632031","median-nerve-cross-sectional-area-and-body-weight-in-carpal-tunnel-syndrome-100632031",false,"NCT07508397","Median Nerve Cross-Sectional Area and Body Weight in Carpal Tunnel Syndrome","The Relationship Between Ultrasonographic Median Nerve Cross-Sectional Area and Electrophysiological Severity in Carpal Tunnel Syndrome Diagnosis: The Masking Role of Body Weight","CTS-US-WEIGHT","Inclusion Criteria:\n\n* Patients aged between 18 and 75 years.\n* Clinical diagnosis of Carpal Tunnel Syndrome (CTS) based on symptoms (numbness, tingling, nocturnal pain in the median nerve distribution).\n* Electrophysiological confirmation of CTS according to the American\n* Association of Neuromuscular \\& Electrodiagnostic Medicine (AAEM) criteria.\n* Ability to provide written informed consent.\n\nExclusion Criteria:\n\n* Secondary causes of CTS (e.g., Diabetes Mellitus, Hypothyroidism, Rheumatoid -Arthritis, Chronic Renal Failure).\n* Coexisting neurological conditions (e.g., Cervical Radiculopathy,\n* Polyneuropathy, Brachial Plexopathy).\n* History of previous wrist surgery, trauma, or local corticosteroid injection within the last 6 months.\n* Pregnancy or lactation.\n* Congenital anatomical variations such as a bifid median nerve or persistent median artery (detected during USG).",true,"ALL","18 Years","75 Years",{"count":22,"type":23},120,"ESTIMATED","OBSERVATIONAL","This study aims to evaluate the diagnostic accuracy of ultrasonographic measurements of the median nerve in patients with Carpal Tunnel Syndrome (CTS). While ultrasound is a common diagnostic tool, various physical factors can influence its results. The researchers will investigate how a patient's absolute body weight and Body Mass Index (BMI) affect the size of the median nerve cross-sectional area across different stages of disease severity. The goal is to determine if absolute body weight plays a 'masking' role that could lead to more precise diagnostic interpretations in clinical practice.",[27,28,29],"Carpal Tunnel Syndrome","Entrapment Neuropathies","Median Nerve Compression",[31,32,33,34,35,36,37,38],"Ultrasonography","Median Nerve","Cross-Sectional Area","Body Weight","Body Mass Index (BMI)","Electromyography","Diagnostic Accuracy","Physical and Rehabilitation Medicine","NOT_YET_RECRUITING","2026-03-30",{"date":42,"type":43},"2026-04-02","ACTUAL",{"date":45,"type":23},"2026-04-01",{"date":47,"type":23},"2026-09-01",{"name":49,"class":50},"Kayseri City Hospital","OTHER_GOV",{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":59,"targetDuration":4,"studyType":61,"phases":62,"briefSummary":64,"conditions":65,"keywords":68,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":83},"100630163","efficacy-of-proximal-median-nerve-release-100630163","NCT07484100","Efficacy of Proximal Median Nerve Release","Efficacy of Operative Versus Conservative Treatment in Proximal Median Nerve Compression","PROMER","Inclusion Criteria:\n\n1. Clinically diagnosed PMNC\n2. If the patient has clinically and electrodiagnostically confirmed carpal tunnel syndrome, at least 6 months must have passed since surgical treatment\n3. Age 18 or over\n4. Ability to understand Finnish\n5. Ability to complete electronic questionnaires independently\n6. Willingness to participate in research and follow research instructions\n7. Provision of informed consent from the participant\n\nExclusion Criteria:\n\n1. Nerve root disorder findings in ENMG\n2. Thoracic outlet syndrome, TOS\n3. Other neurological condition that causes upper limb symptoms such as MS, previous nerve injury\n4. Active rheumatoid arthritis or any other active inflammatory joint disease that affects hand function\n5. Significant compression symptoms of another peripheral nerve in association with PMNC\n6. Other upper extremity operation performed less than 6 months ago\n7. Another disease or condition that accounts for most of the patient's symptoms\n8. Other known reasons that may prevent participation or implementation of treatment during the study",{"count":60,"type":23},160,"INTERVENTIONAL",[63],"NA","A multi-center randomized controlled clinical trial which determines the efficacy of proximal median nerve release in patients with persistent proximal median nerve compression. The primary outcome is patient reported improvement of symptoms on a 7-point Likert scale at 6 months after the randomization to treatment group.",[66,29,67],"Carpal Tunnel Surgery","Median Nerve Entrapment",[69,70,71,72],"proximal median nerve entrapment","proximal median nerve compression","proximal median nerve release","randomized controlled trial","2026-03-17",{"date":75,"type":43},"2026-03-19",{"date":77,"type":23},"2026-03-01",{"date":79,"type":23},"2041-07",{"name":81,"class":82},"Tampere University Hospital","OTHER",2,{"id":85,"slug":86,"hasResults":11,"nctId":87,"briefTitle":88,"officialTitle":89,"acronym":4,"eligibilityCriteria":90,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":91,"enrollmentInfo":92,"targetDuration":4,"studyType":61,"phases":94,"briefSummary":95,"conditions":96,"keywords":99,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":112},"100626463","magnetotherapy-in-carpal-tunnel-syndrome-randomized-controlled-study-100626463","NCT07435961","Magnetotherapy in Carpal Tunnel Syndrome: Randomized Controlled Study","Evaluation of the Effectiveness of Magnetotherapy in Patients With Carpal Tunnel Syndrome: A Placebo-Controlled, Triple-Arm, Randomized, Double-Blind Study","Inclusion Criteria:\n\n* Adults aged between 18 and 65 years.\n\nClinical diagnosis of carpal tunnel syndrome (CTS) based on physical examination findings, including positive Tinel and\u002For Phalen tests and hypoesthesia in the 3rd to 5th digits.\n\nElectrophysiologically confirmed mild-to-moderate carpal tunnel syndrome based on electromyography (EMG) findings.\n\nExclusion Criteria:\n\n* Severe carpal tunnel syndrome confirmed electrophysiologically by electromyography (EMG).\n\nHistory of previous surgical intervention for carpal tunnel syndrome.\n\nPresence of other peripheral nerve entrapments (e.g., ulnar nerve entrapment, radial nerve entrapment).\n\nElectrophysiologically confirmed polyneuropathy or cervical radiculopathy\u002Fcervical discopathy.\n\nRheumatologic diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus).\n\nDiabetes mellitus (Type 1 or Type 2).\n\nPregnancy.\n\nPresence of electronic implants such as cardiac pacemaker, cochlear implant, or implantable defibrillator.\n\nActive acute infection.\n\nHistory of malignancy.\n\nReceipt of physical therapy or rehabilitation for the wrist or surrounding area within the past 6 months.\n\nCorticosteroid injection to the wrist within the past 6 months.\n\nHyperthyroidism or adrenal gland hyperfunction.\n\nOpen growth plates (epiphyseal plates not closed).\n\nParoxysmal neurological disorders (e.g., epilepsy).\n\nMyasthenia gravis.\n\nRegular use of pain medications such as pregabalin, duloxetine, or non-steroidal anti-inflammatory drugs (NSAIDs).","65 Years",{"count":93,"type":23},60,[63],"This study is designed to investigate the effectiveness of low-frequency pulsed electromagnetic field therapy in individuals diagnosed with mild-to-moderate carpal tunnel syndrome (CTS). This double-blind, randomized controlled trial will randomly assign participants into three groups:\n\nGroup 1: Active magnetotherapy\n\nGroup 2: Placebo magnetotherapy (treatment using an identical device that does not generate a magnetic field)\n\nGroup 3: Routine (conservative) treatment group\n\nAll participants will receive a standard nighttime wrist splint and a standardized nerve and tendon gliding exercise protocol. Magnetic field applications will be administered five days per week for a total of 15 sessions. Assessments will be conducted at baseline (T0), at the end of treatment (T1 - Week 3), at 1 month (T2), and at 3 months (T3).\n\nThe primary outcome measures include the Boston Carpal Tunnel Questionnaire (BCTQ), pain intensity assessed by the Visual Analog Scale (VAS), functional status measured by QuickDASH, median nerve cross-sectional area assessed by ultrasonography, sensory function evaluated using the Semmes-Weinstein monofilament test, grip strength measured by dynamometry, and clinical test results (Tinel and Phalen tests). Secondary outcomes include sleep quality assessed by the Pittsburgh Sleep Quality Index (PSQI) and patient satisfaction.\n\nThis study aims to contribute to the scientific evidence regarding the effectiveness of magnetotherapy as a non-invasive treatment option for carpal tunnel syndrome.",[97,98,29],"Magnetotherapy","Carpal Tunnel Syndrome (CTS)",[100,101,102],"median nerve compression","carpal tunnel syndrome(cts)","magnetotherapy","2026-02-21",{"date":105,"type":43},"2026-02-27",{"date":107,"type":23},"2026-02-01",{"date":109,"type":23},"2026-11-01",{"name":111,"class":82},"Fatih Sultan Mehmet Training and Research Hospital",1]