[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"medical-device-related-pressure-injury\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:medical-device-related-pressure-injury":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":5},"100633032","non-invasive-ventilation-interfaces-and-nasal-pressure-injury-in-preterm-infants-100633032",false,"NCT07521410","Non-Invasive Ventilation Interfaces and Nasal Pressure Injury in Preterm Infants","Comparison of the Effects of Different Non-Invasive Ventilation Interfaces on the Development of Medical Device-Related Nasal Pressure Injury in Preterm Infants","NIV-MDRPI","Inclusion Criteria:\n\n* Preterm infants with a gestational age between 28 and 37 weeks\n* Receiving non-invasive ventilation support in a neonatal intensive care unit\n* Receiving non-invasive ventilation for at least 4 days\n* Parental consent obtained\n\nExclusion Criteria:\n\n* Infants requiring intubation\n* Presence of congenital anomalies\n* Pre-existing nasal injury or trauma\n* Presence of skin disease\n* Nasal lesions due to previous nasotracheal intubation\n* Upper airway malformations\n* Infants transferred from another center after receiving more than 24 hours of non-invasive ventilation","ALL","0 Minutes","28 Days",{"count":21,"type":22},75,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this randomized controlled clinical trial is to learn whether different non-invasive ventilation interfaces can prevent medical device-related nasal pressure injury in preterm infants receiving respiratory support in a neonatal intensive care unit.\n\nThe main questions it aims to answer are:\n\n* Do different non-invasive ventilation interfaces affect how often nasal pressure injury develops?\n* Do these interfaces affect the severity of nasal pressure injury and the condition of the nasal skin?\n\nResearchers will compare three types of non-invasive ventilation interfaces (binasal prong, nasal cannula, and nasal mask) to see if one method is more effective in reducing nasal pressure injury.\n\nParticipants will:\n\n* Be randomly assigned to one of three groups (binasal prong, nasal cannula, or nasal mask)\n* Receive non-invasive ventilation support using the assigned interface for at least 4 days\n* Have their nasal skin assessed every 12 hours for 96 hours using standardized scales\n* Continue to receive routine care in the neonatal intensive care unit",[28,29],"Medical Device-Related Pressure Injury","Prematurity",[31,32,33,34,35,36,37],"Preterm infants","Non-invasive ventilation","Nasal pressure injury","Medical device-related pressure injury","Neonatal intensive care unit","CPAP","Nasal interface","NOT_YET_RECRUITING","2026-04-13",{"date":41,"type":42},"2026-04-16","ACTUAL",{"date":44,"type":22},"2026-04-20",{"date":46,"type":22},"2026-10-24",{"name":48,"class":49},"Istanbul University - Cerrahpasa","OTHER"]