[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"meniscal-tear\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:meniscal-tear":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,39,72,97,132],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":4},"100642010","effect-of-preoperative-kinesiophobia-on-clinical-outcomes-following-arthroscopic-meniscus-surgery-100642010",false,"NCT07654894","Effect of Preoperative Kinesiophobia on Clinical Outcomes Following Arthroscopic Meniscus Surgery","Effect of Preoperative Kinesiophobia on Clinical Success in Patients Undergoing Arthroscopic Surgery for Meniscal Tears","MEN-KIN","Inclusion Criteria:\n\nAdults aged 18 to 65 years. Diagnosis of meniscal tear confirmed by clinical examination and magnetic resonance imaging (MRI).\n\nPatients scheduled to undergo arthroscopic meniscal surgery. Ability to understand and complete the study questionnaires. Willingness to participate and provide written informed consent. Availability for both preoperative assessment and postoperative 3-month follow-up.\n\nExclusion Criteria:\n\nPrevious surgery on the affected knee. Concomitant anterior cruciate ligament (ACL), posterior cruciate ligament (PCL), or collateral ligament injuries requiring surgical treatment.\n\nAdvanced knee osteoarthritis (e.g., Kellgren-Lawrence grade 3 or 4). History of inflammatory rheumatic disease or active joint infection. Neurological disorders affecting lower extremity function or balance. Severe psychiatric disorders or cognitive impairment preventing completion of questionnaires.\n\nPregnancy. Inability or unwillingness to provide written informed consent. Inability to attend the 3-month postoperative follow-up.","ALL","18 Years","65 Years",{"count":21,"type":22},50,"ESTIMATED","OBSERVATIONAL","Meniscal tears are among the most common knee injuries and frequently require arthroscopic surgical treatment when conservative management fails or mechanical symptoms persist. Although surgical techniques have improved clinical outcomes, postoperative recovery is influenced not only by structural pathology but also by psychological factors. Kinesiophobia, defined as an excessive and debilitating fear of movement due to pain or the expectation of reinjury, may negatively affect rehabilitation adherence, functional recovery, and pain perception.\n\nThis prospective observational study aims to investigate the effect of preoperative kinesiophobia on postoperative clinical outcomes in patients undergoing arthroscopic surgery for meniscal tears. Adult patients diagnosed with a meniscal tear by clinical examination and magnetic resonance imaging and scheduled for arthroscopic surgery will be enrolled. Preoperative demographic and clinical characteristics, pain intensity, functional status, and kinesiophobia levels will be assessed using validated outcome measures. Postoperative evaluations will be performed three months after surgery to determine changes in pain and functional outcomes. The relationship between preoperative kinesiophobia and postoperative clinical success will be analyzed. The findings of this study may help identify patients at risk for suboptimal recovery and support the development of individualized rehabilitation strategies.",[26],"Meniscal Tear","NOT_YET_RECRUITING","2026-06-12",{"date":30,"type":31},"2026-06-17","ACTUAL",{"date":33,"type":22},"2026-06-25",{"date":35,"type":22},"2026-12-30",{"name":37,"class":38},"Medipol University","OTHER",{"id":40,"slug":41,"hasResults":11,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":45,"eligibilityCriteria":46,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":47,"enrollmentInfo":48,"targetDuration":4,"studyType":50,"phases":51,"briefSummary":53,"conditions":54,"keywords":57,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":71},"100608671","semitendinosus-autograft-vs-meniscal-allograft-in-post-meniscectomy-syndrome-100608671","NCT07204587","Semitendinosus Autograft vs Meniscal Allograft in Post-Meniscectomy Syndrome","A Stratified, Partially Randomized Study Comparing Autologous Semitendinosus Tendon Graft and Meniscal Allograft Transplantation in Young Adults With Post-Meniscectomy Syndrome","MAT","Inclusion Criteria:\n\n* Adults aged 18 to 45 years\n\nHistory of partial meniscectomy \\> 6 months prior to enrollment\n\nSymptomatic post-meniscectomy syndrome (knee pain, swelling, or functional decline)\n\nMRI showing cartilage status ≤ Outerbridge grade 2\n\nKnee joint stability (or stabilized during the index surgery)\n\nBody mass index (BMI) \\\u003C 30\n\nWillingness to provide written informed consent\n\nExclusion Criteria:\n\nTibial slope \\> 16°\n\nRadiographic or arthroscopic evidence of advanced cartilage degeneration (Outerbridge \\> 2 or ICRS ≥ 3)\n\nPresence of inflammatory arthritis or systemic inflammatory joint disease\n\nHistory of cartilage repair surgery\n\nMalalignment \\> 5° not corrected\n\nUntreated ligamentous instability\n\nAny other condition judged by the investigator to compromise study participation or outcomes","45 Years",{"count":49,"type":22},40,"INTERVENTIONAL",[52],"NA","This multicenter, stratified, partially randomized clinical trial aims to compare autologous semitendinosus tendon graft and meniscal allograft transplantation (MAT) in young adults with post-meniscectomy syndrome. The meniscus plays a critical role in load distribution, shock absorption, and joint stability. After meniscectomy, insufficient meniscal tissue often leads to persistent pain, swelling, and functional decline, increasing the risk of early osteoarthritis.\n\nTwo reconstructive strategies are clinically available: MAT provides immediate biomechanical function but requires donor matching and carries higher costs, while autologous tendon graft offers stable supply and no immunologic risk but lacks long-term clinical validation.\n\nIn this study, 40 patients aged 18-45 years will be enrolled. Participants will be allocated into four groups (randomized MAT, randomized autograft, patient-preference MAT, patient-preference autograft). All procedures will use a two-tunnel fixation technique with additional internal brace support.\n\nThe primary endpoint is the improvement in KOOS (Knee Injury and Osteoarthritis Outcome Score) at 24 months postoperatively. Secondary endpoints include MRI-based assessment of graft morphology and extrusion, reoperation rate, complications, patient satisfaction, and return-to-sport time.\n\nThis trial will provide critical evidence regarding the comparative effectiveness and feasibility of tendon autograft versus meniscal allograft in real-world clinical settings, potentially informing surgical decision-making and future treatment guidelines for post-meniscectomy syndrome.",[55,26,56],"Meniscal Injuries","Meniscus Lesion",[58,59,60,61],"meniscal allograft","autologous tendon graft","Post-meniscectomy syndrome","Meniscus deficiency","2025-09-24",{"date":64,"type":31},"2025-10-02",{"date":66,"type":22},"2025-10-01",{"date":68,"type":22},"2029-09-30",{"name":70,"class":38},"Chang Gung Memorial Hospital",1,{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":4,"eligibilityCriteria":78,"healthyVolunteers":11,"sex":17,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":4,"studyType":50,"phases":83,"briefSummary":84,"conditions":85,"keywords":4,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":96},"100443380","this-is-a-study-to-verify-if-marrow-venting-procedure-can-improve-meniscal-suture-healing-100443380","NCT05053646","This is a Study to Verify if Marrow Venting Procedure Can Improve Meniscal Suture Healing","Biological Augmentation Of Meniscal Repair With Marrow Venting: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Arthroscopic confirmed suturable meniscal tears,\n* Monolateral meniscal tears,\n* 18-45 years,\n* BMI\\>18,5 and \\\u003C35 kg\u002Fm2,\n* Ability to give informed consent by signature.\n\nExclusion Criteria:\n\n* Bilateral meniscal tears requiring treatment,\n* Associated ligament lesions requiring treatment,\n* Associated cartilage lesions (Outerbridge \\> 2),\n* Knee axis deformities requiring correction\n* Generalized ligamentous laxity,\n* Radiographic knee ostheoarthritis,\n* Other reasons for knee pain,\n* Pregnant or lactating women,\n* Serious systemic diseases such as cardiac, hepatic or renal failure, rheumatic diseases, non-compensated diabetic, psychological illnesses, central or peripheral neurological diseases, and autoimmune diseases,\n* Enrolled in another ongoing clinical trial.","16 Years","50 Years",{"count":82,"type":22},80,[52],"Meniscal suture represents the current surgical practice, and marrow venting is a low risk procedure. Bone venting may be able to improve the outcome of meniscal repair, allowing the patient a better recovery.",[26],"RECRUITING","2025-08-05",{"date":89,"type":31},"2025-08-06",{"date":91,"type":31},"2021-12-29",{"date":93,"type":22},"2030-10-01",{"name":95,"class":38},"Christian Candrian",2,{"id":98,"slug":99,"hasResults":11,"nctId":100,"briefTitle":101,"officialTitle":102,"acronym":4,"eligibilityCriteria":103,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":104,"enrollmentInfo":105,"targetDuration":4,"studyType":50,"phases":106,"briefSummary":108,"conditions":109,"keywords":113,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":123,"lastUpdatePostDateStruct":124,"startDateStruct":126,"completionDateStruct":128,"leadSponsor":130,"locationsCount":71},"100575662","phase-4-partial-meniscal-replacement-with-spongioflex-100575662","NCT06775197","Partial Meniscal Replacement with Spongioflex®","Sterile Allogeneic Spongioflex® Allograft As Partial Meniscal Replacement After Incomplete Meniscal Loss, an Investigator-initiated Trial","Inclusion Criteria:\n\n1. Patients (male and female) with:\n2. Partial loss of portions of the\n\n   * lateral meniscus and lateral joint line pain OR\n   * medial meniscus and medial joint line pain\n3. sufficient standing of the peripheral rim, so that the procedure can be performed\n4. Age: 18-60 years\n5. signed written informed consent to the study and to provide the scientific data in pseudonymized form\n\nExclusion Criteria:\n\n1. The presence of anterior cruciate ligament insufficiency which is not resolved by reconstruction of the anterior cruciate ligament within 16 weeks after partial meniscal implantation.\n2. Axial deviation (\\>2° varus or valgus)\n3. realignment osteotomy not performed within 12 weeks\n4. advanced cartilage damage (grade III according to ICRS) and osteoarthrosis in the affected compartment (grade III according to Kellgren and Lawrence \\[33\\])\n5. Extension deficit of more than 3° compared to the opposite side or a knee flexion of less than 125°\n6. inflammatory arthritis or synovitis on the treated knee\n7. BMI greater than 30 kg\u002Fm²\n8. \\\u003C18 years, \\>60 years\n9. Chronic pain patients\n10. only for patients who will be operated:\n\n    1. with increased anaesthesiologic risk, e.g., with known or predicted difficult airway\n    2. with increased risk of bleeding\n    3. with increased risk of infection\n    4. with necrotic, infected, or poorly perfused host sides\n    5. history of allergic reactions\n    6. acute hypersensitivity reactions to the IMP or any of its excipients\n    7. pregnant woman","60 Years",{"count":49,"type":22},[107],"PHASE4","The purpose of this investigator-initiated trial is to evaluate whether the novel graft can prevent\u002Freduce the disadvantages of the previously used replacement materials and shows better results than the group of patients, which were not operated. Since there is currently no alternative made of biological material to this product, this investigator-initiated trial is of great medical and economic importance. The otherwise following arthrosis or knee prosthesis implantation (TKA ) could be prevented or at least postponed. Initial clinical results are promising.\n\nAn important and sensitive parameter for assessing the postoperative function of the meniscus is the MRI image. Genovese et al. 2007 were able to show in a categorization\u002Fclassification which magnetic resonance image can be expected in the case of successful incorporation. Several studies have shown that the known clinical knee scores (Lysholm, IKDC, KOOS, VAS pain) improve significantly after successful ingrowth of the meniscus implant.",[110,111,112,56,55,26],"Partial Meniscal Loss","Lateral Meniscus Partial Loss","Medial Meniscal Partial Loss",[114,115,116,117,118,119,120,121,122],"partial meniscal loss","Allograft","Spongioflex®","IKDC","KOOS","return to sport","Outerbridge score","extrusion","VAS pain score","2025-01-09",{"date":125,"type":31},"2025-01-15",{"date":127,"type":31},"2024-11-05",{"date":129,"type":22},"2031-11-05",{"name":131,"class":38},"Maria-Josef-Hospital Greven",{"id":133,"slug":134,"hasResults":11,"nctId":135,"briefTitle":136,"officialTitle":137,"acronym":4,"eligibilityCriteria":138,"healthyVolunteers":139,"sex":17,"minAge":18,"maxAge":104,"enrollmentInfo":140,"targetDuration":4,"studyType":50,"phases":142,"briefSummary":143,"conditions":144,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":145,"lastUpdatePostDateStruct":146,"startDateStruct":148,"completionDateStruct":150,"leadSponsor":152,"locationsCount":71},"100562482","nanoscope-cost-analysis-study-100562482","NCT06603740","Nanoscope Cost Analysis Study","Randomized Study Evaluating Cost of Arthrex Nano Arthroscopy Products in Arthroscopic Knee Meniscectomy Versus Conventional Arthroscopy","Inclusion Criteria:\n\n1. Subject requires simple partial posterior or mid-body meniscectomy.\n2. Subject is 18 - 60 years of age.\n3. Subject body mass index (BMI) is 35 or lower (BMI ≤ 35).\n4. Subject signed informed consent and is willing and able to comply with all study requirements and follow-up visits.\n5. Confirmed meniscal injury by physical exam as per standard of care.\n6. Normal mechanical alignment; \\\u003C 5° varus and \\\u003C 7° valgus, of the affected knee by clinical assessment or X-Rays as per standard of care\n\nExclusion Criteria:\n\n1. Subject requires complex repair or anterior meniscectomy.\n2. Subject has a concomitant chondral lesion of the ipsilateral knee in addition to meniscal tear.\n3. Current bilateral knee injury.\n4. Insufficient quantity or quality of bone.\n5. Blood supply limitations and previous infections which may retard healing.\n6. Congenital ligamentous hypermobility defined by Beighton score 4 or 5.\n7. Locked knee or haemarthrosis.\n8. Subjects that are skeletally immature.\n9. Advanced Osteoarthritis; Kellgren Lawrence ≥ 2\n10. Fracture of the lower extremities within 6 months prior to screening.\n11. Previous surgery on the affected knee within 12 months prior to screening.\n12. Sensitivity to silicone, polyester, nylon, FD\\&C Blue No. 2 dye and beeswax.\n13. Other concomitant disease that would interfere with study outcomes.\n14. Subject is included in a vulnerable population (child, prisoner, etc).\n15. Conditions that tend to limit the patient's ability or willingness to restrict activities, follow directions, or perform online subject assessments during the healing period.\n16. Subject is requesting or receiving Worker's compensation related to the knee injury. -",true,{"count":141,"type":22},10,[52],"The study is a pilot study designed to generate preliminary data regarding the cost of partial meniscectomy using NanoScope versus conventional arthroscopy in a traditional operating room (OR) setting",[26],"2024-09-17",{"date":147,"type":31},"2024-09-19",{"date":149,"type":22},"2024-11",{"date":151,"type":22},"2025-07",{"name":153,"class":154},"Arthrex, Inc.","INDUSTRY"]