[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"meniscus-tear\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:meniscus-tear":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,13,0,[8,46,75,109,137,158,194,217,240,265,287,311,327],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100641432","reducing-disparities-in-knee-arthroscopy-for-adolescents-100641432",false,"NCT07580625","Reducing Disparities in Knee Arthroscopy for Adolescents","RED KARD: Reducing Disparities in Knee Arthroscopy for Adolescents","RED KARD","Inclusion Criteria:\n\n* Predominantly Hispanic soccer team\n* Players between 14-18 years of age\n\nExclusion Criteria:\n\n-Players younger than 14 or older than 18 years of age","ALL","14 Years","18 Years",{"count":21,"type":22},80,"ESTIMATED","INTERVENTIONAL",[25],"NA","Hundreds of thousands of youth athletes require surgery for knee injuries annually. The incidence of operative knee injuries has skyrocketed, but surgery can be delayed due to late recognition and barriers, such as insurance, language, and difficulty navigating the healthcare system. Delays may have lifelong effects, including arthritis, persistent instability, poor patient reported outcomes, and reoperation. There is little patient-centered research on barriers to orthopaedic care, and none on interventions to reduce disparities in pediatric sports medicine. This study will focus on Hispanic children, a growing population nationally and 38% of the Chicago's children, who are at increased risk of delayed knee surgery and its sequelae compared to white, non-Hispanic patients. The overall objectives are to identify barriers to timely knee surgery in Hispanic athletes and develop an intervention to implement evidence on expedient treatment. The aim of this study is to evaluate feasibility, acceptability, and appropriateness of a culturally-tailored intervention in a pilot study of Hispanic youth soccer leagues. The proposed study will drive creation of a future community trial of a culturally-tailored intervention.",[28,29,30,31,32],"Knee Injury","ACL Injury","Meniscus Tear","Hispanic or Latino","Adolescent","NOT_YET_RECRUITING","2026-06-16",{"date":36,"type":37},"2026-06-18","ACTUAL",{"date":39,"type":22},"2027-10-01",{"date":41,"type":22},"2029-07",{"name":43,"class":44},"Ann & Robert H Lurie Children's Hospital of Chicago","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":17,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":23,"phases":57,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":45},"100406426","early-phase-1-montelukast-as-a-potential-chondroprotective-treatment-following-anterior-cruciate-ligament-reconstruction-mocha-trial-100406426","NCT04572256","MOntelukast as a Potential CHondroprotective Treatment Following Anterior Cruciate Ligament Reconstruction (MOCHA Trial)","MOCHA","Inclusion Criteria:\n\n1. Undergoing primary ACL reconstruction\n2. Age between 25-50\n3. Concomitant meniscus injury\n\nExclusion Criteria:\n\n1. Undergoing revision procedures\n2. Multiple ligament injuries requiring multiple ligament reconstruction\u002Frepair\n3. Depressive symptoms and\u002For those who endorse suicidal ideation at the time of enrollment (PHQ-9 score \\>= 15)\n4. Found to not have a meniscus tear at the time of surgery","25 Years","50 Years",{"count":56,"type":22},30,[58],"EARLY_PHASE1","This is a multicenter randomized, placebo-controlled trial to assess whether a 6-month course of oral montelukast after ACL reconstruction reduces systemic markers of inflammation and biochemical and imaging biomarkers of cartilage degradation. This study will specifically target older ACL reconstruction patients with concomitant meniscal injuries as this group is at greatest risk of rapid PTOA progression. Patients will randomly be assigned to receive oral montelukast (10 mg) versus placebo daily for 6 months after surgery.",[29,30,61],"Post-traumatic Osteoarthritis",[63,64],"knee ligament","osteoarthritis","RECRUITING","2026-06-08",{"date":68,"type":37},"2026-06-10",{"date":70,"type":37},"2021-02-01",{"date":72,"type":22},"2027-06",{"name":74,"class":44},"Austin V Stone",{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":4,"eligibilityCriteria":81,"healthyVolunteers":82,"sex":17,"minAge":83,"maxAge":84,"enrollmentInfo":85,"targetDuration":4,"studyType":23,"phases":87,"briefSummary":88,"conditions":89,"keywords":90,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":108},"100557033","the-effect-of-therapeutic-exercise-on-cartilage-morphology-and-physical-function-for-individuals-at-high-risk-of-knee-osteoarthritis-100557033","NCT06532851","The Effect of Therapeutic Exercise on Cartilage Morphology and Physical Function for Individuals at High Risk of Knee Osteoarthritis","The Efficacy of Progressive Resistance Exercises Versus Aerobic Exercises on Cartilage Morphology and Physical Function in Patients With Degenerative Meniscus Tear: A Randomized Controlled Trial","Inclusion Criteria:\n\n1. Are between 35 and 55 years of age.\n2. Have a symptomatic degenerative medial meniscus tear as evidenced by:\n\n   * Presence of medial knee pain.\n   * Medial joint line tenderness.\n   * Pain and limited motion when attempting to perform a full squat and\n   * Increased intra-meniscal signal on at least 2 consecutive MRI slices and\n3. Have clearance from their personal physician to participate in an exercise program.\n\nExclusion Criteria:\n\n1. Radiographic evidence of OA (K-L grade 2 or above).\n2. A repairable meniscus injury (longitudinal tear in the outer 1\u002F3 of the meniscus).\n3. A meniscus injury that requires meniscectomy (locked knee).\n4. Prior or current ligament injury or surgery of the involved knee.\n5. Prior or current injury or surgery to contra-lateral knee.\n6. Pathological ligamentous laxity upon examination of the knee\n7. An inflammatory arthritic condition or\n8. Any injury or condition involving the lower extremities that affects their ability to walk.\n\nBecause participation in this study requires undergoing MRI, subjects will be excluded if they:\n\n1. If female, pregnant at the time of enrollment.\n2. Had prior surgery for an aneurysm; any medical illness that may interfere with the patient's general fitness or exercise capability.\n3. Had any contraindication with MRI.\n4. Had surgery within the past two months.\n5. Have a cardiac pacemaker.",true,"35 Years","55 Years",{"count":86,"type":22},50,[25],"This randomized controlled trial aims to evaluate the efficacy of progressive resistance exercises (PRE) versus aerobic exercises on cartilage morphology and physical function in patients with degenerative meniscus tears. 45 participants, aged 35-55, will be randomly assigned to one of three groups: PRE, aerobic exercise, or control (standard of care physical and medical therapy). The study will utilize MRI T2 mapping to assess changes in cartilage composition and patient-reported and performance-based measures to evaluate clinical outcomes. This pilot study will also determine the feasibility and issues related to recruitment and retention for a larger trial.",[30],[91,92,93,94,95,96,97,98],"Degenerative Meniscus Tear","MRI T2 Mapping","Progressive Resistance Exercise","Aerobic Exercise","Knee Pain","Cartilage Morphology","Exercise Therapy","Early Knee Osteoarthritis","2026-05-07",{"date":101,"type":37},"2026-05-12",{"date":103,"type":37},"2023-06-01",{"date":105,"type":22},"2031-03-01",{"name":107,"class":44},"Jordan University of Science and Technology",2,{"id":110,"slug":111,"hasResults":11,"nctId":112,"briefTitle":113,"officialTitle":114,"acronym":4,"eligibilityCriteria":115,"healthyVolunteers":11,"sex":17,"minAge":19,"maxAge":116,"enrollmentInfo":117,"targetDuration":4,"studyType":23,"phases":119,"briefSummary":122,"conditions":123,"keywords":124,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":128,"lastUpdatePostDateStruct":129,"startDateStruct":131,"completionDateStruct":133,"leadSponsor":134,"locationsCount":136},"100482318","phase-1-study-to-evaluate-the-safety-and-efficacy-of-am3101-to-augment-meniscal-healing-100482318","NCT05560477","Study to Evaluate the Safety and Efficacy of AM3101 to Augment Meniscal Healing","A Prospective, Randomized, Controlled, Double-Blinded, Multi-Center, Phase 1\u002F2b Study to Evaluate the Safety and Efficacy of AM3101 to Augment Meniscal Healing","Inclusion Criteria:\n\n1. Male or female ≥ 18 and ≤ 40 years old at time of screening.\n2. MRI evidence of ACL plus meniscus tear, or isolated meniscus tear.\n3. Body mass index (BMI) ≤ 40 kg\u002Fm2.\n4. Liver and kidney function panels within normal ranges at time of screening\n5. Willing and able to comply with the study procedures and visit schedule, and able to follow oral and written instructions.\n6. Willing and able to sign an IRB approved informed consent\n\nExclusion Criteria:\n\n1. Have any concomitant ligament injury requiring surgical repair or reconstruction other than the ACL.\n2. Have a history of previous meniscus injury that currently needs to be treated or has been treated surgically.\n3. Have evidence of arthritis ≥ Grade III (Outerbridge classification) in the affected compartment or greater than Kellgren Lawrence Grade 3.\n4. Elevated AST or ALT liver enzymes at time of screening\n5. Pregnant or nursing mothers, or women planning on getting pregnant during the time they will be participating in the study.\n6. Known drug or alcohol dependence currently or within the last year.\n7. Participating concurrently in another clinical study or have participated in a clinical study within the last 90 days, or intend to during the course of the study.\n8. Any medical condition or other circumstances that might interfere with the ability to return for follow-up visits in the judgment of the Investigator, including any systemic illness, neuromuscular, neurosensory, or musculoskeletal deficiency that would render the subject unable to perform appropriate postoperative rehabilitation.\n9. Any condition which, in the judgment of the Investigator, would preclude adequate evaluation of the investigational product's safety and efficacy.\n10. Known allergic reaction to simvastatin.\n11. Patients currently taking simvastatin, or any other drug that is within the statin drug classification family.","40 Years",{"count":118,"type":22},74,[120,121],"PHASE1","PHASE2","The purpose of this clinical trial is to assess the safety and efficacy of AM3101 to facilitate meniscal repair and reduce the incidence of non-healing complications and morbidities associated with a failed meniscal repair. This is a prospective, randomized, controlled, double-blinded, multi-center study.",[30],[125,126,127],"meniscal repair","complications","morbidities","2026-04-28",{"date":130,"type":37},"2026-05-04",{"date":132,"type":37},"2023-04-26",{"date":72,"type":22},{"name":135,"class":44},"University of Cincinnati",3,{"id":138,"slug":139,"hasResults":11,"nctId":140,"briefTitle":141,"officialTitle":142,"acronym":4,"eligibilityCriteria":143,"healthyVolunteers":11,"sex":17,"minAge":19,"maxAge":144,"enrollmentInfo":145,"targetDuration":4,"studyType":23,"phases":146,"briefSummary":147,"conditions":148,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":149,"lastUpdatePostDateStruct":150,"startDateStruct":152,"completionDateStruct":154,"leadSponsor":156,"locationsCount":45},"100519301","bridge-enhanced-acl-repair-bear-in-meniscus-repair-100519301","NCT06041763","Bridge-Enhanced ACL Repair (BEAR) in Meniscus Repair","Outcomes Following Meniscal Repair With the BEAR Implant: A Randomized Controlled Trial","Inclusion Criteria:\n\n• History of meniscus injury indicated for isolated repair, without concomitant ligament reconstruction or repair, cartilage repair procedure, or osteotomy.\n\nExclusion Criteria:\n\n* Patients who are undergoing meniscal repair for displaced bucket-handle meniscal tears\n* Patients with a history of blood-borne diseases including HIV, hepatitis B virus, hepatitis C virus, human T-lymphotropic virus, and syphilis","75 Years",{"count":21,"type":22},[25],"The bridge-enhanced ACL repair (BEAR) implant is a collagen-based scaffold loaded with whole blood. It is designed to promote healing in the setting of intraarticular knee pathology. This study would compare clinical outcomes and synovial fluid cytokine profiles in patients who undergo isolated meniscal repair with or without the BEAR implant.",[30],"2026-02-23",{"date":151,"type":37},"2026-02-25",{"date":153,"type":37},"2024-11-20",{"date":155,"type":22},"2027-11",{"name":157,"class":44},"NYU Langone Health",{"id":159,"slug":160,"hasResults":11,"nctId":161,"briefTitle":162,"officialTitle":163,"acronym":164,"eligibilityCriteria":165,"healthyVolunteers":82,"sex":17,"minAge":19,"maxAge":166,"enrollmentInfo":167,"targetDuration":4,"studyType":169,"phases":4,"briefSummary":170,"conditions":171,"keywords":173,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":185,"lastUpdatePostDateStruct":186,"startDateStruct":188,"completionDateStruct":190,"leadSponsor":192,"locationsCount":108},"100621130","magic-angle-direction-imaging-madi-acl-study-100621130","NCT07366619","Magic Angle Direction Imaging (MADI) ACL Study","Diagnostics of the Anterior Cruciate Ligament (ACL) Using Magic Angle Directional Imaging (MADI)","MADI","Inclusion Criteria:\n\n* adults aged 18 - 65 years\n* selected for ligament repair surgery\n* ability to give informed consent, either written or e-consent\n* no contraindications to MRI\n* BMI ≤ 28 or thigh circumference less than 47 cm at approximately 7.5cm above the joint line\n\nExclusion Criteria:\n\n* acutely unwell or frail patients in whom extension of scanning time may not be tolerated or may delay treatment\n* contraindications to MRI\n* participants who are too big to be able to fit in the prototype scanner\n* recent surgery to the affected joint\n* severe pain\n* pregnant and\u002For breastfeeding participants","65 Years",{"count":168,"type":22},20,"OBSERVATIONAL","This study will be conducted to see if a new Magnetic Resonance Imaging (MRI) scanner could give additional information or help view the body in a different way. The new scanner may be useful to diagnose conditions affecting tissues such as ligaments, tendons and cartilage more accurately, potentially improving the quality of care by the NHS. To develop such protocols and to test the clinical capabilities of the scanner, it is necessary to evaluate the scans of healthy volunteers before recruiting patient participants.\n\nConventional MRI scans are unable to detect the signal from tissues such as ligaments, tendons, cartilage and cortical bone, which contain highly aligned collagen fibres and the signal decays too quickly to be captured. These tissues appear black and are only seen because of the surrounding brighter tissues. If a bright region appears, it can be a sign of an injury or disease, but it can also appear due to the Magic Angle artefacts, when the collagen fibres are at a specific angle to the main magnetic field of the MR scanner. This anomaly can make assessment of these tissues difficult. Currently the diagnostic gold standard is arthroscopy, though it is mostly undertaken therapeutically.\n\nThe method harnesses this inherent tissue property to gain information about these collagen-rich tissues in joints. Using Magic Angle Direction Imaging (MADI) it is possible to obtain detailed information about the collagen fibre structures, and this is not available using conventional MRI. MADI could be important for planning surgery, developing new tissue implants, and monitoring outcome measures.\n\nIn both standard cylindrical scanner and the conventional open scanner, it is impossible to move the magnet, nor the patient, in the required manner. This motivated the development of a novel prototype MA scanner that can move around the patient.\n\nThe aim of this study is to evaluate the ability to routinely perform in-vivo Magic Angle-MRI of collagen structures in joints based on the magic angle principle, and to assess the ability to use qualitative and quantitative assessment of the Magic Angle-MR images to distinguish between the pathologies of the soft structures imaged.",[172,30],"Anterior Cruciate Ligament Injuries",[174,175,176,177,178,179,180,181,182,183,184],"magic angle","musculoskeletal","low field","magnetic resonance imaging (MRI)","knee","ACL","degenerative meniscus","patellar tendon","magic angle directional imaging (MADI)","short T2","collagen fibre orientation","2026-01-16",{"date":187,"type":37},"2026-01-26",{"date":189,"type":37},"2025-01-29",{"date":191,"type":22},"2027-06-30",{"name":193,"class":44},"Imperial College London",{"id":195,"slug":196,"hasResults":11,"nctId":197,"briefTitle":198,"officialTitle":198,"acronym":199,"eligibilityCriteria":200,"healthyVolunteers":11,"sex":17,"minAge":19,"maxAge":54,"enrollmentInfo":201,"targetDuration":203,"studyType":169,"phases":4,"briefSummary":204,"conditions":205,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":208,"lastUpdatePostDateStruct":209,"startDateStruct":211,"completionDateStruct":213,"leadSponsor":215,"locationsCount":45},"100555065","clinical-and-instrumental-assessment-of-meniscal-root-tears-treated-through-suture-to-the-posterior-cruciate-ligament-100555065","NCT06507241","Clinical and Instrumental Assessment of Meniscal ROOT Tears Treated Through Suture to the Posterior Cruciate Ligament","ROOT-PCL","Inclusion Criteria:\n\n1. Age between 18 and 50 years at the time of surgery;\n2. Male and female gender;\n3. Patients undergoing surgical treatment for at least one year for \"ROOT\" type meniscal lesions using arthroscopic suturing to the posterior cruciate ligament;\n4. Pre-operative MRI performed.\n\nExclusion Criteria:\n\n1. Patients no longer reachable;\n2. Patients who refuse consent to the study;\n3. Previous meniscectomy before surgery;\n4. Previous ligament injuries before surgery;\n5. New traumatic injuries after surgery;\n6. Advanced knee osteoarthritis (Outerbridge grade III-IV) at the time of surgery;\n7. Severe knee malalignment (\\> 5°) at the time of surgery;\n8. Severe obesity (BMI \\> 35);\n9. Lower limb conditions preventing full weight-bearing during evaluation;\n10. Infection or hematological\u002Frheumatic conditions at the time of evaluation.",{"count":202,"type":22},59,"2 Years","The menisci are crucial for knee stability and functionality. Composed of fibrocartilaginous structure, they have an anatomical and biomechanical arrangement that makes them essential for load transmission and the prevention of osteoarthritis. Meniscal root lesions, known as \"ROOT tears,\" compromise their protective function on the cartilage, leading to increased contact pressures between the tibia and femur and, over time, the development of osteoarthritis. Early diagnosis of these lesions is difficult and often the first detection is incidental. The subsequent challenges are significant due to a lack of pre-operative planning. A possible solution is a surgical technique involving arthroscopic suture of the posterior meniscal root along with the posterior cruciate ligament. This procedure does not require pre-operative planning and is applicable even in cases of incidental diagnosis.",[30,206,207],"Meniscus Lesion","Knee Injuries","2025-11-18",{"date":210,"type":37},"2025-11-19",{"date":212,"type":37},"2024-10-18",{"date":214,"type":22},"2027-12",{"name":216,"class":44},"Istituto Ortopedico Rizzoli",{"id":218,"slug":219,"hasResults":11,"nctId":220,"briefTitle":221,"officialTitle":222,"acronym":223,"eligibilityCriteria":224,"healthyVolunteers":11,"sex":17,"minAge":19,"maxAge":54,"enrollmentInfo":225,"targetDuration":4,"studyType":23,"phases":227,"briefSummary":228,"conditions":229,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":231,"lastUpdatePostDateStruct":232,"startDateStruct":234,"completionDateStruct":236,"leadSponsor":238,"locationsCount":108},"100557718","fibrine-clot-augmented-repair-of-longitudinal-meniscus-tears-100557718","NCT06541756","Fibrine Clot-augmented Repair of Longitudinal Meniscus Tears","Fibrine Clot-augmented Repair of Longitudinal Meniscus Tears - A Prospectively Randomized Controlled Trial","FCAR","Inclusion Criteria:\n\n* Presenting with a painful meniscus (lateral or medial) longitudinal tear\n* Being between the ages of 18 and 50\n* Not having undergone surgery on the same knee before\n* Having an MRI taken at the end of the 1st year post-surgery\n\nExclusion Criteria:\n\n* Having additional collateral ligamentous damage along with the meniscus tear (such as MCL or LCL)\n* Incomplete clinical scores at the end of the study\n* A history of previous surgery on the same knee\n* Having an active infection\n* Not having a control MRI at the end of the 1st year",{"count":226,"type":22},120,[25],"Longitudinal meniscal tears are a type of meniscal injury characterized by a displaced fragment of the meniscus that flips over into the joint, often resembling a buckle or handle. These tears typically occur in the medial meniscus and are often associated with traumatic knee injuries, particularly in athletes.\n\nThe displaced meniscal fragment can cause mechanical symptoms such as locking, clicking, or catching of the knee, as well as pain and swelling. If not properly treated, buckle-handle meniscal tears can lead to further complications, including chronic knee instability, increased risk of osteoarthritis, and persistent joint pain.Repairing a longitudinal meniscal tear offers several advantages over partial meniscectomy, particularly in preserving knee function and preventing long-term complications.\n\nMeniscal repair aims to restore the integrity of the meniscus, which plays a crucial role in load distribution, shock absorption, and joint stability.\n\nUtilizing a fibrin clot during the repair of a buckle-handle meniscal tear can enhance the healing process and improve surgical outcomes. Fibrin clots act as a biological scaffold, promoting tissue regeneration by providing a matrix that facilitates cellular migration and proliferation.\n\nThe purpose of this study was to compare longitudinal meniscal tear repair reinforced with fibrin clot with routine end-to-end repair in a prospective randomized controlled trial.",[30,206,230,207],"Fibrin Blood Clot","2025-09-29",{"date":233,"type":37},"2025-10-02",{"date":235,"type":37},"2024-07-25",{"date":237,"type":22},"2029-07-31",{"name":239,"class":44},"Ankara City Hospital Bilkent",{"id":241,"slug":242,"hasResults":11,"nctId":243,"briefTitle":244,"officialTitle":245,"acronym":4,"eligibilityCriteria":246,"healthyVolunteers":11,"sex":17,"minAge":19,"maxAge":116,"enrollmentInfo":247,"targetDuration":4,"studyType":23,"phases":249,"briefSummary":250,"conditions":251,"keywords":252,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":256,"lastUpdatePostDateStruct":257,"startDateStruct":259,"completionDateStruct":261,"leadSponsor":263,"locationsCount":45},"100565773","the-effect-of-anti-gravity-treadmill-training-in-patients-with-meniscus-tears-100565773","NCT06646536","The Effect of Anti-Gravity Treadmill Training in Patients With Meniscus Tears","The Effect of Anti-Gravity Treadmill Training on Symptoms and Functions in Patients With Meniscus Tears","Inclusion Criteria:\n\n* Age between 18-40 years old\n* Clinical history and symptoms consistent with MRI-confirmed meniscus tear\n\nExclusion Criteria:\n\n* History of previous knee surgery\n* Other knee ligament pathologies\n* Neurological disorders",{"count":248,"type":22},48,[25],"The aim of this study is to evaluate the effect of anti-gravity treadmill training on symptoms and functions in patients with meniscus tears.",[30],[253,254,255],"meniscus","anti-gravity","exercise","2025-07-07",{"date":258,"type":37},"2025-07-08",{"date":260,"type":37},"2025-01-20",{"date":262,"type":22},"2026-09",{"name":264,"class":44},"Bezmialem Vakif University",{"id":266,"slug":267,"hasResults":11,"nctId":268,"briefTitle":269,"officialTitle":270,"acronym":4,"eligibilityCriteria":271,"healthyVolunteers":11,"sex":17,"minAge":19,"maxAge":272,"enrollmentInfo":273,"targetDuration":4,"studyType":23,"phases":275,"briefSummary":276,"conditions":277,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":278,"lastUpdatePostDateStruct":279,"startDateStruct":281,"completionDateStruct":283,"leadSponsor":285,"locationsCount":45},"100519267","novel-bioactive-sleeve-on-pain-and-proms-100519267","NCT06041321","Novel Bioactive Sleeve on Pain and PROMs","The Effect of a Novel Bioactive Sleeve on Postoperative Pain and Patient Reported Outcome Scores After Arthroscopic Meniscectomy and Meniscus Repairs: A Randomized Placebo Controlled Study","Inclusion Criteria:\n\n* Provision of signed and dated informed consent form\n* Stated willingness to comply with all study procedures and availability for the duration of the study\n* Male or female, over the age of 18, undergoing a meniscectomy or meniscus repair\n* In good general health as evidenced by medical history\n* Under 45th percentile BMI\n* Willing to adhere to the study intervention regimenregimen.\n* Kellgren-Lawrence grade 2 or less\n\nExclusion Criteria:\n\n* Febrile illness within 3 months\n* BMI over 40\n* Treatment with another investigational drug or other intervention within 6 months\n* Kellgren-Lawrence grade 3 or more or 4\n* History of autoimmune disease, circulatory disease, or vascular disorder","89 Years",{"count":274,"type":22},100,[25],"A novel bioactive sleeve will be compared to a placebo sleeve with a similar look and feel to assess pain outcomes, patient reported outcome measures, and effectiveness of healing based on range of motion.",[30],"2024-01-16",{"date":280,"type":37},"2024-01-18",{"date":282,"type":37},"2023-12-06",{"date":284,"type":22},"2027-10",{"name":286,"class":44},"Northwell Health",{"id":288,"slug":289,"hasResults":11,"nctId":290,"briefTitle":291,"officialTitle":292,"acronym":4,"eligibilityCriteria":293,"healthyVolunteers":11,"sex":17,"minAge":294,"maxAge":295,"enrollmentInfo":296,"targetDuration":4,"studyType":23,"phases":297,"briefSummary":298,"conditions":299,"keywords":301,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":302,"lastUpdatePostDateStruct":303,"startDateStruct":305,"completionDateStruct":307,"leadSponsor":309,"locationsCount":45},"100519806","fnb-in-meniscal-tear-under-sa-100519806","NCT06048341","FNB in Meniscal Tear Under SA","Effects of Sono-guided Femoral Nerve Block in Arthroscopic Surgery for Meniscal Tear Under Spinal Anesthesia: A Randomized Controlled Trial","Inclsuion Criteria:\n\n* individuals who are scheduled to undergo meniscal surgery and must be received sufficient explanation about the research prior to surgery and have provided their informed consent to participate.\n\nExclusion Criteria:\n\n* who require simultaneous surgery for concomitant cartilage injury, collateral ligament tear.\n* who have previously undergone surgical treatment within the knee joint.\n* who have declined to participate in the research.\n* where medical, surgical, or anesthetic complications occurred during surgery.\n* other cases deemed necessary by the researchers.","19 Years","60 Years",{"count":274,"type":22},[25],"The investigators will compare the results of sono-guided femoral nerve block in arthroscopic surgery for meniscal tear under spinal anesthesia",[30,300],"Femoral Nerve Block",[30,300],"2023-09-20",{"date":304,"type":37},"2023-09-22",{"date":306,"type":22},"2023-09-18",{"date":308,"type":22},"2026-09-18",{"name":310,"class":44},"Chuncheon Sacred Heart Hospital",{"id":312,"slug":313,"hasResults":11,"nctId":314,"briefTitle":315,"officialTitle":316,"acronym":4,"eligibilityCriteria":317,"healthyVolunteers":11,"sex":17,"minAge":294,"maxAge":295,"enrollmentInfo":318,"targetDuration":4,"studyType":23,"phases":319,"briefSummary":320,"conditions":321,"keywords":322,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":302,"lastUpdatePostDateStruct":323,"startDateStruct":324,"completionDateStruct":325,"leadSponsor":326,"locationsCount":45},"100519617","fnb-in-meniscal-tear-under-ga-100519617","NCT06045884","FNB in Meniscal Tear Under GA","Effects of Sono-guided Femoral Nerve Block in Arthroscopic Surgery for Meniscal Tear Under General Anesthesia: A Randomized Controlled Trial","Inclusion Criteria:\n\n\\- individuals who are scheduled to undergo meniscal surgery and must be received sufficient explanation about the research prior to surgery and have provided their informed consent to participate.\n\nExclusion Criteria:\n\n* who require simultaneous surgery for concomitant cartilage injury, collateral ligament tear.\n* who have previously undergone surgical treatment within the knee joint.\n* who have declined to participate in the research.\n* where medical, surgical, or anesthetic complications occurred during surgery.\n* other cases deemed necessary by the researchers.",{"count":274,"type":22},[25],"The investigators will compare the results of sono-guided femoral nerve block in arthroscopic surgery for meniscal tear under general anesthesia",[30,300],[300,30],{"date":304,"type":37},{"date":306,"type":22},{"date":308,"type":22},{"name":310,"class":44},{"id":328,"slug":329,"hasResults":11,"nctId":330,"briefTitle":331,"officialTitle":331,"acronym":4,"eligibilityCriteria":332,"healthyVolunteers":11,"sex":17,"minAge":19,"maxAge":333,"enrollmentInfo":334,"targetDuration":4,"studyType":23,"phases":336,"briefSummary":337,"conditions":338,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":341,"lastUpdatePostDateStruct":342,"startDateStruct":344,"completionDateStruct":346,"leadSponsor":348,"locationsCount":45},"100507069","posteromedial-tibiofemoral-incongruence-pmtfi-treatment-100507069","NCT05882591","Posteromedial Tibiofemoral Incongruence (PMTFI) Treatment","Inclusion Criteria:\n\n* Pain, snapping or discomfort in posterior part of the knee in deep knee flexion during squat\n* Reduced concavity of the femoral metaphysis proximal to the medial femoral condyle confirmed on MRI\n* Impingement of posterior horn of medial meniscus with the metaphysis of femur during full knee flexion confirmed arthroscopically\n\nExclusion Criteria:\n\n* Active knee inflammation\n* Chondral injuries ICRS 3-4\n* Extraarticular reasons of pain, snapping or discomfort in posterior part of the knee in deep knee flexion during squat\n* Cyst or avascular changes within the femoral metaphysis adjacent to the planned localization of the procedure","70 Years",{"count":335,"type":22},10,[25],"The aim of this study is to assess outcomes of Posteromedial Tibiofemoral Incongruence (PMTFI) Treatment",[339,340,30,206],"Meniscus Disorder","Meniscus; Degeneration","2023-05-20",{"date":343,"type":37},"2023-05-31",{"date":345,"type":37},"2020-10-09",{"date":347,"type":22},"2027-12-31",{"name":349,"class":44},"Artromedical Konrad Malinowski Clinic"]