[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"menstrual-cup\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:menstrual-cup":34},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,55,79],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":35,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":49,"leadSponsor":51,"locationsCount":54},"100608318","impact-of-internal-menstrual-protections-on-immunity-and-vaginal-microbiota-100608318",false,"NCT07199998","Impact of Internal Menstrual Protections on Immunity and Vaginal Microbiota","Impact of the Use of Internal Menstrual Protections on Immunity and Vaginal Microbiota","CUPS2","Inclusion Criteria:\n\n* Willingness to comply with all study procedures and availability for the duration of the study.\n* Female, aged 18 to 49 years.\n* In general good health, as determined by medical history.\n* Covered by the national health insurance system.\n* Willing to sign a written informed consent form.\n* Has already experienced menstruation prior to the start of the study.\n* No vaginal sexual intercourse within 72 hours before the study visit.\n* Has had at least 6 menstrual periods in the past 12 months.\n\nExclusion Criteria:\n\n* HIV infection.\n* Positive diagnosis for chlamydia or syphilis at screening or within 4 weeks prior to screening.\n* History of hormonal disorders or menstrual cycle irregularities.\n* Metrorrhagia.\n* Pregnancy or breastfeeding.\n* Family members or close relatives of the clinical or scientific team.\n* Treatment with any medication for chronic inflammatory disease or chronic conditions (e.g., cancer, arthritis, transplantation) within the past 12 months.\n* Participation in an ongoing clinical trial.\n* Receiving or having received antibiotic treatment within the 4 weeks prior to the study.\n* Refusal to be informed in case of detected abnormalities.\n* Indistinct use of both tampons and menstrual cups.\n* Never having had vaginal penetrative intercourse.",true,"FEMALE","18 Years","49 Years",{"count":22,"type":23},300,"ESTIMATED","OBSERVATIONAL","The availability, effectiveness, and safety of menstrual protection represent a key public health issue. However, research on women's menstrual and sexual health remains extremely limited. Whether societal or pathological, many hypotheses are emerging regarding the effects of menstrual protection products, yet little attention has been given to the products themselves, their societal role, or their physiological and pathological consequences. Internal menstrual products, such as tampons and menstrual cups, are widely used but are subject to limited regulatory oversight, and few studies have investigated their long-term effects on vaginal health.\n\nThis study aims to investigate how different types of menstrual protection influence vaginal microbiota, immune responses, and the recurrence of gynecological conditions such as bacterial vaginosis, mycosis, or dysbiosis. Biological samples (vaginal, cervical, urinary, and blood) will be collected to analyze vaginal microbiota composition and local immunity. Participants will be divided into three groups based on their main type of menstrual protection: menstrual cup users, tampon users, and external pad users. The study will compare these groups to assess potential differences in vaginal health and immune response related to menstrual product use.",[27,28,29,30,31,32,33,34],"Sexual Transmitted Disease","Vaginosis, Bacterial","Mycosis","Urogenital Disease","HPV","Dysbiosis","Toxic Shock Syndrome","Menstrual Cup",[36,32,37,38,39,40,41],"Menstrual cup","Menstrual health","Menstrual protection","Menstrual pad","Tampon","Immunity","RECRUITING","2026-04-08",{"date":45,"type":46},"2026-04-09","ACTUAL",{"date":48,"type":46},"2026-04-07",{"date":50,"type":23},"2027-03",{"name":52,"class":53},"Centre National de la Recherche Scientifique, France","OTHER",1,{"id":56,"slug":57,"hasResults":11,"nctId":58,"briefTitle":59,"officialTitle":59,"acronym":4,"eligibilityCriteria":60,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":61,"enrollmentInfo":62,"targetDuration":4,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":4,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":54},"100458778","pilot-study-of-suction-as-a-mechanism-of-iud-expulsion-with-concomitant-menstrual-cup-use-100458778","NCT05254041","Pilot Study of Suction as a Mechanism of IUD Expulsion With Concomitant Menstrual Cup Use","Inclusion Criteria:\n\n* Female\n* Between the ages of 18-45\n* Currently has an FDA approved IUD\n* Present to CWHC for IUD removal\n\nExclusion Criteria:\n\n* Known sensitivity or allergy to silicone\n* known active vaginal infection (yeast, bacterial vaginosis, untreated sexually transmitted infection)\n* IUD strings not visible\n* Positive pregnancy test","45 Years",{"count":63,"type":23},80,"INTERVENTIONAL",[66],"NA","This study will provide pilot data examining suction as a mechanism of IUD displacement with menstrual cup use. The investigator hypothesize that manufacturer-recommended menstrual cup insertion and removal by breaking the seal will result in 15% rate of IUD displacement\u002Fexpulsion. The investigator will also use this data to explore variables associated with IUD displacement and menstrual cup use. By examining the role of suction as a possible mechanism of IUD displacement, this research will allow healthcare providers to better counsel patients who use IUDs regarding menstrual cup use. Having a better understanding of the mechanics of IUD displacement could lead to the development of strategies to prevent expulsion.",[69,34],"IUD; Complications, Mechanical","2026-02-10",{"date":72,"type":46},"2026-02-12",{"date":74,"type":46},"2022-02-20",{"date":76,"type":23},"2026-12-31",{"name":78,"class":53},"University of Colorado, Denver",{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":4,"eligibilityCriteria":85,"healthyVolunteers":11,"sex":18,"minAge":86,"maxAge":20,"enrollmentInfo":87,"targetDuration":4,"studyType":64,"phases":89,"briefSummary":90,"conditions":91,"keywords":94,"overallStatus":96,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":4},"100603526","the-use-of-menstrual-cups-in-the-menstrual-health-and-hygiene-management-of-women-who-use-wheelchairs-100603526","NCT07137663","The Use of Menstrual Cups in the Menstrual Health and Hygiene Management of Women Who Use Wheelchairs","Investigation of the Use of Menstrual Cups in the Menstrual Health and Hygiene Management of Women Using Wheelchairs","Inclusion Criteria:\n\n* Having previously used a method other than a menstrual cup during menstruation,\n* Being between 18 and 45 years of age,\n* Having a regular menstrual cycle between 21-35 days,\n* Not having a diagnosed and treated sexually transmitted infection,\n* Not having a silicone allergy,\n* Not having a known vaginal anatomical defect,\n* Being able to actively use both arms and hands.\n\nExclusion Criteria:\n\n* Planning to become pregnant,\n* Having had a urogenital tract infection in the past 3 months (based on self-report),\n* Having known conditions such as fibroids, endometritis, gynecological disorders, renal colic, or hydronephrosis.","15 Years",{"count":88,"type":23},30,[66],"This study is designed to evaluate the impact of menstrual cup use on menstrual health and hygiene management among women who use wheelchairs.In addition, the study will serve as a reference for future research that includes other groups of people with disabilities and will contribute to the literature. The main questions it aims to answer are:\n\nHow does menstrual cup use affect the menstrual hygiene management experiences of women who use wheelchairs?\n\nWhat impact does menstrual cup use have on women's comfort, perception of hygiene, and participation in social life?\n\nDo women's knowledge, attitudes, and satisfaction levels regarding menstrual cup use change over time?\n\nWhy do women who use wheelchairs choose to use or not to use menstrual cups? This quasi-experimental study will use a repeated measures design (within-subjects design). Participants included in the study will be scheduled for an appointment to receive training on menstrual cup use and to be provided with a menstrual cup. The training will be conducted face-to-face in the education room of the relevant association. During this session, the participant will first respond to the initial part of the questionnaire. Following that, she will receive training on menstrual cup use (supported by video, models, etc.), and based on the information obtained, a menstrual cup in a suitable size will be provided. The menstrual cups to be used by the participants will be supplied by the researcher.\n\nAfter the initial meeting, six follow-up interviews will be conducted following the 1st, 2nd, 3rd, 4th, 5th, and 6th menstrual periods. In each session, participants will be asked to complete a follow-up-specific questionnaire, and any questions they have will be answered. Their use of the menstrual cup will be assessed during each follow-up. If a participant is not using the cup, the reasons for non-use will be explored, and if desired, the training will be repeated or individual counseling will be provided. If the participant refuses counseling or states that she no longer wishes to use the cup, she will be withdrawn from the study. If a participant drops out during the first three follow-ups, a new participant will be recruited to replace her.",[34,92,93],"Menstrual Hygiene Management","Disabled People",[34,92,95],"Persons with Disability","NOT_YET_RECRUITING","2025-08-21",{"date":99,"type":46},"2025-08-22",{"date":101,"type":23},"2025-11-01",{"date":103,"type":23},"2027-11-02",{"name":105,"class":53},"Hülya ULAŞLI KABAN"]