[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"mental-and-behavioural-disorders\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:mental-and-behavioural-disorders":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,54],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":53},"100612785","innov5-mh-maroc-integrated-mental-health-care-for-adolescents-and-adults-in-primary-care-centers-and-schools-in-morocco-100612785",false,"NCT07258095","INNOV5-MH-MAROC: Integrated Mental Health Care for Adolescents and Adults in Primary Care Centers and Schools in Morocco","INNOV5-MH-MAROC: Multicenter Pragmatic Randomized Controlled Trial Evaluating an Integrated Program of Five WHO Innovations in Mental Health in Morocco","INNOV5-MH","Inclusion Criteria:\n\n* Adolescents (12-17 years) and adults (≥18 years) attending participating primary care centres or high schools in Morocco.\n* Clinically significant depressive and\u002For anxiety symptoms identified by screening (PHQ-9 and\u002For GAD-7) according to study thresholds.\n* Able to understand study procedures and provide informed consent (or parental consent and adolescent assent for minors).\n* Planning to remain in the study area for at least 12 months.\n\nExclusion Criteria:\n\n* Acute psychiatric emergency requiring immediate specialised care (e.g. psychosis, high-risk suicidal crisis, severe substance use disorder).\n* Cognitive impairment or severe medical condition preventing participation in the intervention or assessments.\n* Current participation in another interventional mental health trial.\n* Any other situation judged by the investigator to make participation unsafe or inappropriate.","ALL","12 Years",{"count":20,"type":21},146,"ESTIMATED","INTERVENTIONAL",[24],"NA","Depression and anxiety are highly prevalent among adolescents and adults in Morocco, while access to evidence-based care in primary care centers and schools remains limited. This multicenter pragmatic randomized controlled trial evaluates an integrated mental health program inspired by WHO priorities. The INNOV5 intervention combines: (1) a collaborative care model in primary care; (2) mhGAP-based task-shifting and stepped care; (3) validated digital mental health interventions; (4) virtual reality exposure therapy for selected anxiety- or trauma-related cases; and (5) a school-based mental health promotion component in participating high schools. The primary objective is to compare the change in depressive symptoms (PHQ-9) at 6 months between INNOV5 and enhanced treatment as usual (TAU+). Secondary objectives include effects on anxiety (GAD-7), quality of life (WHOQOL-BREF), suicidal ideation and behavior (C-SSRS), functioning, school attendance, and feasibility and acceptability of the program.",[27,28,29,30],"Depression in Adolescence","Depression in Adults","Anxiety","Mental and Behavioural Disorders",[32,29,33,34,35,36,37,38,39,40],"Depression","Adolescent mental health","Primary care","School-based mental health","Digital mental health","Virtual reality exposure","mhGAP","Task-shifting","Morocco","NOT_YET_RECRUITING","2025-11-20",{"date":44,"type":45},"2025-12-02","ACTUAL",{"date":47,"type":21},"2028-03-01",{"date":49,"type":21},"2029-12-31",{"name":51,"class":52},"Swiss Medical Academy Maroc","OTHER",1,{"id":55,"slug":56,"hasResults":11,"nctId":57,"briefTitle":58,"officialTitle":58,"acronym":4,"eligibilityCriteria":59,"healthyVolunteers":60,"sex":17,"minAge":61,"maxAge":4,"enrollmentInfo":62,"targetDuration":64,"studyType":65,"phases":4,"briefSummary":66,"conditions":67,"keywords":88,"overallStatus":90,"whyStopped":4,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":53},"100440334","anovaos-network-powered-patient-registry-100440334","NCT05013944","AnovaOS Network Powered Patient Registry","Inclusion Criteria:\n\n* 18 years old or older;\n* Confirmed positive diagnosis of disease, condition or disorder. This will be self-reported or reported by the patient's provider, advocacy group or other patient representative;\n* Laboratory or other independent means of confirmation is not required but may be confirmed in clinical trials;\n* Able to understand and willing to sign the informed consent document; or whose legal representative has given consent to participate in the research per state and Federal requirements;\n* Willing and able to complete the registry questions or have the instrument(s) completed by an informed proxy;\n* Anticipated additional follow up with the registry once per year.\n\nExclusion Criteria:\n\n* Subjects who do not meet the inclusion criteria for the study;\n* Subjects who are unable to understand the protocol or unable to provide legally effective informed consent",true,"18 Years",{"count":63,"type":21},100000,"5 Years","OBSERVATIONAL","The objective of this study is the development, implementation and management of a registry of patient data that captures clinically meaningful, real-world, data on the diagnosis, nature, course of infection, treatment(s) and outcomes in patients with complex disease globally.",[68,69,70,71,30,72,73,74,75,76,77,78,79,80,81,82,83,84,85,86,87],"Infectious Disease","Neoplasms","Diseases of the Blood and Blood-Forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89)","Endocrine, Nutritional and Metabolic Diseases (E00-E89)","Diseases of the Nervous System","Diseases of the Eye and Adnexa","Diseases of the Ear and Mastoid Process","Diseases of the Circulatory System","Diseases of the Respiratory System","Diseases of the Digestive System","Diseases of the Skin and Subcutaneous Tissue","Diseases of the Musculoskeletal System and Connective Tissue","Diseases of the Genitourinary System","Pregnancy, Childbirth and the Puerperium","Certain Conditions Originating in the Perinatal Period","Congenital Malformations, Deformations and Chromosomal Abnormalities (Q00-Q99)","Symptoms, Signs and Abnormal Clinical and Laboratory Findings, Not Elsewhere Classified","Injury, Poisoning and Certain Other Consequences of External Causes","External Causes of Morbidity and Mortality","Factors Influencing Health Status and Contact With Health Services",[89],"infectious disease, cancer\u002Foncology, neurology, immunology, cardiology","RECRUITING","2024-01-29",{"date":93,"type":45},"2024-01-30",{"date":95,"type":45},"2021-09-01",{"date":97,"type":21},"2026-08-31",{"name":99,"class":100},"Anova Enterprises, Inc","INDUSTRY"]