[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"mental-disorder-in-adolescence\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:mental-disorder-in-adolescence":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,45,82,113],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100564767","adolescent-psychiatry-inpatients-self-reported-parent-adolescent-communication-quality-and-treatment-outcome-100564767",false,"NCT06633458","Adolescent Psychiatry Inpatients: Self-reported Parent-adolescent Communication Quality and Treatment Outcome","Adolescent Psychiatry Inpatients: Self-reported Parent-adolescent Communication Quality as a Predictor of Treatment Outcome","Inclusion Criteria:\n\n* Admission to inpatient care unit of the adolescent psychiatry at the University Medical Center Hamburg-Eppendorf.\n\nExclusion Criteria:\n\n* Severe symptom burden at admission\n* Lack of knowledge of the German language.","ALL","14 Years","17 Years",{"count":20,"type":21},60,"ESTIMATED","OBSERVATIONAL","The quality of parent-adolescent communication has been found to be associated with adolescent mental health. However, little is known about the association of parent-adolescent communication and adolescent mental health in the context of psychiatry inpatient treatment.\n\nThis study aims to find out whether self-reported parent-adolescent communication quality at the time of admission to psychiatry predicts the treatment outcome in terms of symptom reduction 6 months later in an adolescent inpatient sample. It also aims to track changes in adolescent self-reported communication quality in the course of inpatient treatment and afterwards (2, 4 and 6 months after admission) to see whether improvement predicts treatment outcome, with treatment outcome being defined as symptom reduction to baseline. As a secondary endpoint, it will be assessed whether a placement of the adolescent outside the family was considered during treatment and whether self-reported communication quality at the time of admission predicts the consideration of placement outside the family.",[25,26,27],"Mental Disorder in Adolescence","Depression in Adolescence","Anxiety",[29,30,31],"mental health","adolescence","communication","RECRUITING","2026-06-28",{"date":35,"type":36},"2026-07-01","ACTUAL",{"date":38,"type":36},"2024-07-08",{"date":40,"type":21},"2027-10-30",{"name":42,"class":43},"Universitätsklinikum Hamburg-Eppendorf","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":52,"sex":53,"minAge":54,"maxAge":18,"enrollmentInfo":55,"targetDuration":4,"studyType":57,"phases":58,"briefSummary":60,"conditions":61,"keywords":69,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":81},"100480983","cognitive-behavioral-therapy-and-exercise-training-in-adolescents-at-risk-for-type-2-diabetes-100480983","NCT05543083","Cognitive-Behavioral Therapy and Exercise Training in Adolescents At-Risk for Type 2 Diabetes","CBTeX","Inclusion Criteria:\n\n* Female\n* Age 12-17 years\n* Body Mass Index (BMI)\\>= 85 for age and sex\n* Type 2 Diabetes (T2D) first-or second-degree relative\n* Center for Epidemiologic Studies Depression Scale (CES-D) total score \\>=21\n\nExclusion Criteria:\n\n* T2D\u002F Type 1 Diabetes (T1D) or any major medical condition (e.g. cardiovascular, renal) that would prohibit the ability to participate in exercise training\n* Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) conduct disorder, substance abuse\u002F dependence, obsessive compulsive disorder, panic attacks, post-traumatic stress disorder, anorexia\u002Fbulimia, \\& schizophrenia\n* Insulin sensitizers, weight loss medications \\& chronic steroids\n* Structured weight loss treatment or bariatric surgery\n* Pregnancy, nursing",true,"FEMALE","12 Years",{"count":56,"type":21},300,"INTERVENTIONAL",[59],"NA","The investigators are doing this study to learn more about how to prevent type 2 diabetes in teenage girls. The purpose of this study is to find out if taking part in a cognitive-behavioral therapy group, exercise training group, or a combination of cognitive-behavioral therapy and exercise training groups, decreases stress, improves mood, increases physical activity and physical fitness, and decreases insulin resistance among teenagers at risk for diabetes.",[62,63,64,65,25,66,67,68],"Insulin Resistance","Depression","Depressive Disorder","Mood Disorders","Hyperinsulinism","Glucose Metabolism Disorders","Metabolic Disease",[70,71],"Adolescent Type 2 Diabetes Prevention","Exercise Training","2026-04-17",{"date":74,"type":36},"2026-04-22",{"date":76,"type":36},"2023-06-02",{"date":78,"type":21},"2029-03-31",{"name":80,"class":43},"Colorado State University",2,{"id":83,"slug":84,"hasResults":11,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":4,"eligibilityCriteria":88,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":89,"enrollmentInfo":90,"targetDuration":4,"studyType":57,"phases":91,"briefSummary":92,"conditions":93,"keywords":99,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":81},"100540053","building-social-and-structural-connections-for-the-prevention-of-opioid-use-disorder-among-youth-experiencing-homelessness-100540053","NCT06311838","Building Social and Structural Connections for the Prevention of Opioid Use Disorder Among Youth Experiencing Homelessness","Building Social and Structural Connections for the Prevention of Opioid Use Disorder Among Youth Experiencing Homelessness: An RCT Examining Biopsychosocial Mechanisms","Inclusion Criteria:\n\n* Youth must meet the criteria for homelessness as defined by the McKinney-Vento Act: children and youth who lack a fixed, regular, and adequate nighttime residence; or live in a welfare hotel, or place without regular sleeping accommodations, or live in a shared residence with other persons due to the loss of one's housing or economic hardship\n* Must speak english adequately to complete measures\n\nExclusion Criteria:\n\n* Youth who have a stable housing situation.\n* Non-English speaker","24 Years",{"count":56,"type":21},[59],"Homelessness severely affects health and well-being and is particularly negative for youth. Between 70-95% of youth experiencing homelessness (YEH) report problem substance use and 66-89% have a mental health disorder. Youth appear to be at greater risk for living on the streets or being homeless than adults and are more vulnerable to long term consequences of homelessness. Multiple social determinants of health (SDOH) are uniquely associated with homelessness, driving substance use and adverse mental health consequences. However, limited research has identified pragmatic interventions that have a long-term ameliorating impact on the complex, multi-symptomatic issues among these youth. This study overcomes prior gaps in research through testing a multi-component comprehensive prevention intervention targeting SDOH that may affect biopsychosocial health indicators and longer-term health outcomes. In partnership with a drop-in center for YEH, youth between the ages of 14 to 24 years, will be engaged and randomly assigned to conditions using a dismantling design so that essential intervention components can be efficiently identified. In particular, youth (N = 300) will be randomly assigned to a) Motivational Interviewing\u002FCommunity Reinforcement Approach + Services as Usual (MI\u002FCRA + SAU, n = 80), b) Strengths-Based Outreach and Advocacy + Services As Usual (SBOA + SAU, n = 80), c) MI\u002FCRA + SBOA + SAU (n = 80) or d) SAU (n=60) through the drop-in center. In order to assess the longer-term prevention effects on substance use, mental health and other outcomes, all youth will be assessed at baseline and at 3, 6, 12, 18 and 24-months post-baseline. The primary goal of this study is to establish the impact of a comprehensive intervention embedded within a system that serves YEH, a community drop-in center, on youth's opioid misuse and disorder, other substance misuse and disorders, mental health diagnoses, and other targeted outcomes. This study will offer unique information on the physiological and psychological stress pathways underlying change for specific subgroups of youth along with cost estimates to inform future implementation efforts in drop-in centers around the country.",[94,95,96,25,97,98],"Opioid Use Disorder","Dual Diagnosis","Housing Problems","Risk Behavior","Homelessness",[100,101,102,103],"youth experiencing homelessness","social determinants of health","opioid use disorder","substance use","2025-09-18",{"date":106,"type":36},"2025-09-22",{"date":108,"type":36},"2024-05-06",{"date":110,"type":21},"2029-12-01",{"name":112,"class":43},"Ohio State University",{"id":114,"slug":115,"hasResults":11,"nctId":116,"briefTitle":117,"officialTitle":118,"acronym":119,"eligibilityCriteria":120,"healthyVolunteers":11,"sex":16,"minAge":121,"maxAge":122,"enrollmentInfo":123,"targetDuration":4,"studyType":57,"phases":125,"briefSummary":126,"conditions":127,"keywords":130,"overallStatus":137,"whyStopped":4,"lastUpdateSubmitDate":108,"lastUpdatePostDateStruct":138,"startDateStruct":140,"completionDateStruct":142,"leadSponsor":144,"locationsCount":81},"100547383","promoting-sleep-and-physical-activity-among-adolescent-psychiatric-patients-100547383","NCT06407258","Promoting Sleep and Physical Activity Among Adolescent Psychiatric Patients","Transdiagnostic Sleep Intervention Combined With Physical Activity Counseling (SLEEPAC) in Adolescent Psychiatric Patients: A Blended Care Approach","SLEEPAC","Inclusion Criteria:\n\n* Aged between 13 to 18 years\n* Presence of insomnia and\u002For delayed sleep-wake phase disorder\n* At least one further diagnosis of DSM-5\n* Written informed consent of parents \u002F primary caregiver\n\nExclusion Criteria:\n\n* Organic sleep- and brain disorders (i.e., obstructive sleep apnea, narcolepsy, epilepsy)\n* Suffering from medical conditions, which prevent participation in physical activity\n* Changes to medication regime during the study protocol\n* Color-blindness (due to stroop test)","13 Years","18 Years",{"count":124,"type":21},140,[59],"Mental health disorders pose a significant burden on adolescent populations globally, often accompanied by sleep disturbances. Emerging evidence suggests that addressing sleep issues can improve mental health outcomes, while physical activity is increasingly recognized as beneficial for both sleep and mental well-being. This study aims to assess the effectiveness of a novel intervention (SLEEPAC), combining cognitive-behavioral therapy for insomnia (CBT-I), circadian treatment, and PA counseling, compared to treatment as usual (TAU), in improving psychopathology among adolescent psychiatric outpatients with sleep disturbances. Secondary outcomes include improvements in sleep health, physical activity levels, cognitive performance and self-esteem. Additionally, the study seeks to explore the predictive value of sleep neurophysiological biomarkers using high-density sleep electroencephalography (EEG), contributing to advancements in precision psychiatry for this population.",[25,128,129],"Insomnia","Delayed Sleep-Wake Phase Disorder",[131,132,133,134,135,136],"adolescents","CBT-I","light therapy","circadian adaptation","physical activity counseling","transdiagnostic","NOT_YET_RECRUITING",{"date":139,"type":36},"2024-05-09",{"date":141,"type":21},"2024-06-01",{"date":143,"type":21},"2026-06-30",{"name":145,"class":43},"Christin Lang"]