[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"mental-health-conditions\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:mental-health-conditions":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,49,72,98,129,160],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100596338","effect-of-sun-tai-chi-on-the-cardiopulmonary-system-and-mental-health-in-university-students-100596338",false,"NCT07044154","Effect of Sun Tai Chi on the Cardiopulmonary System and Mental Health in University Students","Effect of Sun Tai Chi on the Cardiopulmonary System and Mental Health in University Students: A Mixed Randomized Clinical Trial","Inclusion Criteria:\n\n* Undergraduate university students\n* Aged 18 to 29 years\n* Both sexes\n* Present mental health symptoms assessed by the Depression Anxiety Stress Scales - 21 Items (DASS-21) questionnaire, according to cutoff points established by Lovibond et al., ranging from mild to severe in any of the subscales of stress (score 15 to 33), anxiety (score 8 to 19), or depression (score 10 to 27).\n* Report a healthy physical condition suitable for Tai Chi practice (self-reported).\n\nExclusion Criteria:\n\n* Engage in a high level of physical activity according to the International Physical Activity Questionnaire (IPAQ) or have regularly practiced moderate to high intensity physical activity in the last 3 months.\n* Report chronic illnesses that limit or contraindicate the practice of exercises required in Tai Chi.\n* Present cardiovascular, pulmonary, or neurological diseases.\n* Exhibit either no mental health impairment or severe impairment according to cutoff scores established by Lovibond et al. in the DASS-21 questionnaire (stress subscale score lower than 15 or greater than 33, anxiety subscale score lower than 8 or greater than 19, depression subscale score lower than 10 or greater than 27).\n* Present specific psychiatric diagnoses, such as Attention-Deficit\u002FHyperactivity Disorder (ADHD), self-reported.\n* Consume medications for mental health treatment.\n* Consume medications or substances that influence cardiac autonomic modulation (e.g., beta-blockers).","ALL","18 Years","29 Years",{"count":20,"type":21},56,"ESTIMATED","INTERVENTIONAL",[24],"NA","Currently, university students face physical and mental health issues, which are reflected in low levels of physical activity, a decline in healthy eating behaviors, and a high prevalence of mental health symptoms such as stress, anxiety, and depression. Therefore, it is necessary to develop safe, effective, and sustainable interventions that support comprehensive health and provide formative experiences that reinforce the importance of developing healthy lifestyle habits and self-care.\n\nIn this regard, Tai Chi has been shown to offer physical and mental health benefits. Tai Chi is a low- to moderate-intensity exercise with low joint impact, which facilitates the transition from a sedentary to an active lifestyle.\n\nConsidering the health problems experienced by university students, it is proposed that a Tai Chi intervention could help produce beneficial effects on both physical and mental health. In this context, the present study aims to implement Tai Chi classes with the objective of determining their effect on the cardiac autonomic system, mental health, and the perception of benefits, facilitators, and barriers among participating university students compared to a control group.",[27,28],"Mental Health Conditions","University Students",[30,31,32,33,34,35],"university students","Sun Tai Chi","cardiac autonomic modulation","cardiopulmonary capacity","mental health","qualitative perception","RECRUITING","2026-04-23",{"date":39,"type":40},"2026-04-29","ACTUAL",{"date":42,"type":40},"2025-07-01",{"date":44,"type":21},"2026-08-31",{"name":46,"class":47},"Universidad Católica del Maule","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":57,"targetDuration":4,"studyType":22,"phases":59,"briefSummary":60,"conditions":61,"keywords":4,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":48},"100634649","impact-of-dog-adoption-and-training-in-veterans-with-post-traumatic-stress-symptoms-andor-other-mental-health-conditions-100634649","NCT07542431","Impact of Dog Adoption and Training in Veterans With Post-traumatic Stress Symptoms and\u002For Other Mental Health Conditions","Assessment of Biopsychosocial Indicators Linked to Canine Intervention Treatment Response in Veterans With Post-traumatic Stress Symptoms and\u002For Other Mental Health Conditions","VCRM","Inclusion Criteria:\n\n* Military veteran with self-reported posttraumatic stress symptoms and\u002For other mental health conditions\n* Over 18 years of age\n* Applied and approved to adopt a shelter dog for training through the Humane Society of Broward County in Fort Lauderdale, Florida\n* English speaker (written and spoken)\n* Home internet access via tablet, computer or smartphone.\n\nExclusion Criteria:\n\n* Fear of dogs\n* Allergies to pet dander\n* Uncorrected hearing or visual impairment.",{"count":58,"type":21},120,[24],"The goal of this single-arm study is to learn if a dog adoption and training program can treat, prevent in \\[describe participant population\u002Fprimary condition; could include any of the following: sex\u002Fgender, age groups, healthy volunteers\\]. The main questions it aims to answer are:\n\n* Does the dog adoption and training program decrease posttraumatic stress symptoms in veterans with self-reported posttraumatic stress symptoms?\n* Does the dog adoption and training program decrease stress and improve psychosocial health in veterans with self-reported posttraumatic stress symptoms?\n* Does the dog adoption and training program decrease inflammation, increase oxytocin, and change the structure and resting-state function of specific brain regions in veterans with self-reported posttraumatic stress symptoms?\n\nParticipants will:\n\n* Attend eight one-hour professional dog training sessions within a 10-week period.\n* Visit the clinical research unit four times during the study for data collection.",[62,27],"Posttraumatic Stress Symptoms","2026-04-21",{"date":65,"type":40},"2026-04-24",{"date":67,"type":40},"2026-02-09",{"date":69,"type":21},"2030-12",{"name":71,"class":47},"Florida Atlantic University",{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":4,"eligibilityCriteria":78,"healthyVolunteers":11,"sex":16,"minAge":79,"maxAge":4,"enrollmentInfo":80,"targetDuration":4,"studyType":22,"phases":82,"briefSummary":83,"conditions":84,"keywords":86,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":48},"100634425","a-toolkit-to-improve-mental-health-treatment-for-autistic-individuals-100634425","NCT07539519","A Toolkit to Improve Mental Health Treatment for Autistic Individuals","A Transdiagnostic Toolkit to Improve Mental Health Treatment for Autistic Individuals","The following describes Phase II (the clinical trial):\n\nInclusion Criteria for clients:\n\n* A confirmed diagnosis of autism\n* Between 13 and 17 years old\n* Fluent in English\n* Have a co-occurring mental health condition that is appropriate for treatment at the community clinic participating in the proposed study\n\nExclusion criteria:\n\nN\u002FA\n\nAll therapists working at the community clinic at which this study takes place will be eligible to participate.","13 Years",{"count":81,"type":21},18,[24],"This pilot study is funded by the Organization for Autism Research (OAR). We are conducting a pilot study to improve mental health treatment for autistic individuals. First, we will conduct remote focus groups to identify barriers to mental health treatment and methods to improve treatment. Based on results, we will develop a prototype of a resource for therapists. This resource will be pilot tested in a community clinic.",[85,27],"Autism",[87],"mental health treatment","NOT_YET_RECRUITING","2026-04-13",{"date":91,"type":40},"2026-04-20",{"date":93,"type":21},"2026-04",{"date":95,"type":21},"2027-12",{"name":97,"class":47},"Florida International University",{"id":99,"slug":100,"hasResults":11,"nctId":101,"briefTitle":102,"officialTitle":103,"acronym":104,"eligibilityCriteria":105,"healthyVolunteers":11,"sex":16,"minAge":106,"maxAge":107,"enrollmentInfo":108,"targetDuration":4,"studyType":110,"phases":4,"briefSummary":111,"conditions":112,"keywords":115,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":120,"lastUpdatePostDateStruct":121,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":126,"locationsCount":128},"100578006","prospective-cohort-study-of-protected-children-100578006","NCT06805682","Prospective Cohort Study of Protected Children","PEGASE3, Experimental Program of a Standardized Health Protocol Applied to Children Who Benefited From a Child Protection Measure Before the Age of Five: Effectiveness and Efficiency","ESPER","Inclusion Criteria:\n\n* Child under the supervision of child protective services,\n* Arriving for the first time in a participating center,\n* Less than 42 months old (i.e. 3 and a half years),\n* Non-opposition of the holders of parental authority (in the event of impossibility to obtain the non-opposition of both holders of parental authority, the non-opposition of one of them will be obtained).\n\nExclusion Criteria:\n\n• Children whose child protection measure has not been confirmed by a judicial or administrative decision.","0 Months","42 Months",{"count":109,"type":21},220,"OBSERVATIONAL","A significant number of children are abused or neglected every year. This exposure is associated with short- and long-term consequences for their mental and somatic health. In France, 308,000 minors are benefiting from at least one child protective service or measure. There are few data on the health status of this population, and how it is evolving. Against this backdrop, interventions are needed to address the many needs of these children early and comprehensively, both in the short and long term.\n\nThe PEGASE program, funded by the French government under Article 51, aims to ensure adequate medical follow-up - both somatic and psychiatric - for children taken into care by child protective services (CPS). An evaluation of the program's effectiveness and efficiency is needed to inform public decision-making on the appropriateness of extending it to all children under CPS's care. This requires the creation of a control cohort of children followed by CPS but not benefiting from the PEGASE program, the ESPER cohort (Prospective cohort study of protected children), which will enable us to carry out a comparative evaluation of the PEGASE program, as well as to provide information on the health of children followed by the CPS at the time of their placement and its evolution over time, data which are rare in France.\n\nThe main objective is to evaluate the effectiveness of the PEGASE program on the evolution of the mental health of children followed by the CPS after 2 years of follow-up.",[27,113,114],"Physical Health Status","Child Development",[116,114,117,118,119],"Child Protective Services","Mental health","Cohort study","Comparative study","2026-04-08",{"date":89,"type":40},{"date":123,"type":40},"2025-02-18",{"date":125,"type":21},"2029-02-17",{"name":127,"class":47},"Assistance Publique - Hôpitaux de Paris",7,{"id":130,"slug":131,"hasResults":11,"nctId":132,"briefTitle":133,"officialTitle":134,"acronym":4,"eligibilityCriteria":135,"healthyVolunteers":136,"sex":16,"minAge":137,"maxAge":138,"enrollmentInfo":139,"targetDuration":141,"studyType":110,"phases":4,"briefSummary":142,"conditions":143,"keywords":145,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":151,"startDateStruct":153,"completionDateStruct":155,"leadSponsor":157,"locationsCount":48},"100564025","impact-of-help-seeking-behaviors-on-allergic-rhinitis-and-mental-health-a-longitudinal-study-100564025","NCT06623799","Impact of Help-Seeking Behaviors on Allergic Rhinitis and Mental Health: A Longitudinal Study","Impact of Help-Seeking Behaviors on Allergic Rhinitis, Asthma Control, and Mental Health: A Retrospective and Longitudinal Analysis of Allergy Medication Use","Inclusion Criteria:\n\nAdults (aged 18 years or older) Patients actively receiving care in a primary care setting. Patients who have provided informed consent for their health data to be included in the research repository.\n\nExclusion Criteria:\n\nPatients who have not provided informed consent for their health data to be included in the research repository.\n\nPatients diagnosed with chronic conditions outside the scope of allergic rhinitis, asthma, or mental health conditions (anxiety, depression).\n\nPatients with severe mental health disorders or comorbidities that are unrelated to the conditions of interest (e.g., schizophrenia, bipolar disorder, etc.).",true,"4 Years","100 Years",{"count":140,"type":21},200000,"10 Years","This study explores how help-seeking behaviors for both emotional well-being and allergies impact the management of allergic rhinitis, asthma, and mental health symptoms, including anxiety and depression. The research involves a retrospective and longitudinal analysis of patients who sought treatment for allergic rhinitis and mental health concerns. The goal is to highlight the importance of integrating mental health care into allergy treatment plans to improve overall patient outcomes.",[27,144],"Allergic",[146,147,148,149,150],"Allergic Rhinitis","Asthma Control","Mental Health","Help-Seeking Behaviors","Integrated Care",{"date":152,"type":40},"2026-02-11",{"date":154,"type":40},"2020-01-01",{"date":156,"type":21},"2027-01-25",{"name":158,"class":159},"QHSLab, Inc.","INDUSTRY",{"id":161,"slug":162,"hasResults":11,"nctId":163,"briefTitle":164,"officialTitle":165,"acronym":4,"eligibilityCriteria":166,"healthyVolunteers":136,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":167,"targetDuration":4,"studyType":22,"phases":169,"briefSummary":170,"conditions":171,"keywords":176,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":189,"lastUpdatePostDateStruct":190,"startDateStruct":192,"completionDateStruct":194,"leadSponsor":196,"locationsCount":48},"100592128","implementation-of-the-ascend-training-for-supervisors-in-dutch-small-and-medium-sized-enterprises-smes-100592128","NCT06989398","Implementation of the ASCEND Training for Supervisors in Dutch Small and Medium-sized Enterprises (SMEs)","Cluster RCT of the WHO's Advancing Supervisor Capabilities for Mental Health at Work (ASCEND) in Dutch Small and Medium-sized Enterprises (SMEs)","Inclusion for SMEs:\n\n* Having 10 to 250 employees\n* Being located in the Netherlands\n\nIn case of insufficient recruitment among SMEs, a mitigation strategy is to recruit individual departments from larger organizations.\n\nEligibility criteria for individual participants:\n\nSupervisors are included if they fit the following inclusion criteria:\n\n* 18 years or older\n* Working in an organization in the Netherlands\n* Sufficient mastery (written and spoken) of the language in which the ASCEND intervention is being delivered (i.e., Dutch or English)\n* Written informed consent before entering the study\n* Supervise at least 1 supervisee within the same organization\n\nSupervisees are included if they fit the following inclusion criteria:\n\n* 18 years or older\n* Have a direct supervisor who is participating in ASCEND (either intervention or control group)\n* Sufficient mastery of English or Dutch\n* Written informed consent before entering the study",{"count":168,"type":21},148,[24],"This cluster randomized controlled trial (cRCT) aims to evaluate the effectiveness of an in-person group intervention for workplace supervisors - Advancing Supervisors' Capacity for Mental Health at Work (ASCEND) - in Dutch Small and Medium-sized Enterprises (SMEs). The ASCEND intervention is designed to equip supervisors with the skills to: i) know when to support their workers; ii) how to direct workers to support, and iii) advocate for action on mental health at work.\n\nThe primary objectives of this project are to:\n\n* Assess to what extent the novel, WHO-developed ASCEND intervention is effective in enhancing supervisors' confidence, responsiveness, mental health literacy, and SelfCare practices, and in reducing supervisor stigma towards mental health conditions within Dutch SMEs.\n* Evaluate the impact of the ASCEND intervention on employee outcomes, including mental health and work-related outcomes among supervisees (i.e., subordinates), as well as overall organizational absenteeism rates.\n* Identify barriers, facilitators, and key implementation and adoption indicators to support future opportunities for scaling up the ASCEND intervention in the context of Dutch SMEs.\n\nResearchers will compare two groups to evaluate the effectiveness of the ASCEND intervention. One group will receive the training (the intervention group), while the other group will receive the training after the final follow-up period (the control group).\n\nData will be collected from both supervisors and their supervisees (i.e., subordinates) via online questionnaires at various time points. In addition, general organizational information, including absenteeism rates, will be gathered through a representative from each participating organization.\n\nTo further explore the feasibility of scaling up the ASCEND intervention within the Netherlands, qualitative data will be collected through interviews and\u002For focus group discussions.",[172,173,174,27,175],"Occupational Health","Stress","Burnout","Sickness Absence",[177,178,179,180,181,182,183,184,185,186,187,188],"Workplace mental health","Occupational stress","Sickness absence","Supervisors","Line managers","Absenteeism","Presenteeism","Employee well-being","Workplace intervention","Manager training","ASCEND","Advancing Supervisors' Capacity for Mental Health at Work","2025-11-18",{"date":191,"type":40},"2025-11-19",{"date":193,"type":40},"2025-05-14",{"date":195,"type":21},"2026-09",{"name":197,"class":47},"VU University of Amsterdam"]