[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"mental-health-disorders\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:mental-health-disorders":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,57,87,137,170,191],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":32,"overallStatus":45,"whyStopped":4,"lastUpdateSubmitDate":46,"lastUpdatePostDateStruct":47,"startDateStruct":50,"completionDateStruct":52,"leadSponsor":54,"locationsCount":4},"100642671","study-on-intervention-effect-of-heat-related-health-risk-early-warning-digital-technology-for-school-age-children-100642671",false,"NCT07643571","Study on Intervention Effect of Heat-related Health Risk Early Warning Digital Technology for School-age Children","School inclusion criteria\n\n1. Willing to participate in the study.\n2. Possess adequate facilities and qualified teaching staff.\n3. The school and teachers maintain good cooperation.\n4. Class size is no less than 35 students.\n5. All participating classrooms are equipped with air conditioners.\n\nParticipant inclusion criteria\n\n1. Fourth-grade primary school students aged 9 to 11, of all genders.\n2. Voluntary participation by students and their parents, good compliance, and signed informed consent.\n3. At least one adult family member has an internet-enabled mobile device.\n4. Good general health with no history of severe physical or mental disorders.\n5. Local permanent residents with a residency of no less than 6 months.\n\nParticipant exclusion criteria\n\n1. Participants who are unable or refuse to complete required examinations.\n2. Students receiving psychological or psychiatric treatment that may confound the study results.\n3. Those currently enrolled in other interventional clinical studies that may affect outcome assessment.\n4. Any other conditions deemed ineligible by the research team. Any participant meeting any of the above exclusion criteria will be excluded from the study.",true,"ALL","9 Years","11 Years",{"count":20,"type":21},200,"ESTIMATED","INTERVENTIONAL",[24],"NA","This cluster randomized trial is conducted in Beijing primary schools to evaluate the efficacy of a WeChat mini-program-based high-temperature early warning intervention on the physical and cognitive health of school-age children. Six participating schools are randomly assigned to two parallel groups. The intervention group receives tiered heat alerts and guided self-health monitoring via the mini-program. The control group follows standard daily school and family routines, with no dedicated digital high-temperature early-warning intervention. The primary outcome is children's executive function after a 2.5-month follow-up. A range of secondary indicators related to physical status, mental health and health behaviors are assessed concurrently to quantify the intervention's benefits in mitigating adverse health outcomes caused by high temperatures.",[27,28,29,30,31],"Cardiovascular Diseases","Respiratory Diseases","Mental Health Disorders","Heat Illness","Neurocognitive Impairment",[33,34,35,36,37,38,39,40,41,42,43,44],"Heat stress","heat early warning","digital intervention","WeChat mini-program","school-age children","executive function","Wisconsin Card Sorting Test","cognitive function","cluster randomized controlled trial","children's physical health","heat-related disease","climate change","NOT_YET_RECRUITING","2026-06-09",{"date":48,"type":49},"2026-06-11","ACTUAL",{"date":51,"type":21},"2026-06",{"date":53,"type":21},"2026-09",{"name":55,"class":56},"Centers for Disease Control and Prevention, China","OTHER_GOV",{"id":58,"slug":59,"hasResults":11,"nctId":60,"briefTitle":61,"officialTitle":61,"acronym":4,"eligibilityCriteria":62,"healthyVolunteers":11,"sex":16,"minAge":63,"maxAge":4,"enrollmentInfo":64,"targetDuration":4,"studyType":22,"phases":66,"briefSummary":67,"conditions":68,"keywords":73,"overallStatus":75,"whyStopped":4,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":86},"100632374","the-implementation-of-a-trans-tailored-harm-reduction-service-for-transgender-persons-in-relation-to-chemsex-and-substance-use-it-rex-100632374","NCT07512856","The Implementation of a Trans-tailored Harm Reduction Service for Transgender Persons in Relation to chemsEX and Substance Use (iT-REX)","Inclusion Criteria:\n\n* Self-identified transgender women, transgender men, or non-binary persons\n* Age ≥18 years\n* HIV-negative\n* Engaged in chemsex or substance use within past 12 months\n* Able to provide informed consent\n\nExclusion Criteria:\n\n• Inability to communicate in Thai sufficiently to complete study procedures","18 Years",{"count":65,"type":21},140,[24],"This study evaluates a comprehensive transgender-tailored harm reduction service for transgender women, transgender men, and non-binary individuals engaging in chemsex or substance use in Thailand, focusing on PrEP uptake, HIV\u002FSTI outcomes, mental health, and socio-legal impacts.",[69,70,29,71,72],"HIV Prevention","Substance Use","Sexually Transmitted Infections (STIs)","Chemsex",[74],"PrEP, Harm reduction, Chemsex, Transgender","RECRUITING","2026-04-02",{"date":78,"type":49},"2026-04-06",{"date":80,"type":49},"2024-02-01",{"date":82,"type":21},"2028-02-01",{"name":84,"class":85},"Institute of HIV Research and Innovation Foundation, Thailand","OTHER",1,{"id":88,"slug":89,"hasResults":11,"nctId":90,"briefTitle":91,"officialTitle":92,"acronym":93,"eligibilityCriteria":94,"healthyVolunteers":11,"sex":16,"minAge":95,"maxAge":63,"enrollmentInfo":96,"targetDuration":4,"studyType":22,"phases":98,"briefSummary":99,"conditions":100,"keywords":107,"overallStatus":75,"whyStopped":4,"lastUpdateSubmitDate":127,"lastUpdatePostDateStruct":128,"startDateStruct":130,"completionDateStruct":132,"leadSponsor":134,"locationsCount":86},"100620990","effectiveness-of-the-soundheal-multi-sensory-integrative-therapy-among-justice-involved-youth-100620990","NCT07364799","Effectiveness of the SoundHeal Multi-Sensory Integrative Therapy Among Justice-Involved Youth","Effectiveness of the SoundHeal (Heal) Multi-Sensory Integrative Therapy in Enhancing Emotional Regulation Among Justice-Involved Youth and Its Effect on Therapeutic Alliance and Mental Health Outcomes","HEAL-SLOJSC","Inclusion Criteria:\n\n* Age: Youth 12-18 years old. All participants enrolled in this study will be under the age of 18 at time of enrollment.\n* Custody: Detained in SLO County, CA Juvenile Hall with at least 8 weeks of expected stay at the time the clinical trial starts\n* Diagnosis: Documented history of being at risk or of having a history or current diagnosis of a mental health disorder (depression, anxiety, stress) and\u002For SUD\n* Language\u002FComprehension: Basic English understanding; accommodations for limited literacy allowed\n* Consent\u002FAssent: Eligible juveniles must provide assent, with parent\u002Fguardian or Legally Authorized Representative (LAR) consent.\n* Ensure that the person providing informed consent understands the information provided, even if that person providing informed consent agrees to be in the research.\n* Participation: Willingness to comply with the Heal intervention, journaling, and questionnaires\n* Recruitment and selection participation: Eligible participants will be selected in collaboration with facility behavioral-health staff using objective inclusion criteria only. Recruitment procedures are designed to be fair and free from arbitrary influence by facility administrators or peers.\n\nSpecial Considerations: Because participants are minors and incarcerated, safeguards ensure voluntary participation, protection from coercion, age-appropriate communication, and accommodations for literacy or comprehension limits.\n\nExclusion Criteria:\n\n* Age\u002FStatus: Not between 12-18 years old, or not currently detained in SLO County Juvenile Hall\n* Length of Stay: Expected detention is less than 8 weeks at start of clinical trial\n* Clinical Stability: Determined by onsite staff to be medically or psychiatrically unable to participate safely\n* Consent\u002FAssent: Unable to provide assent, or if parent\u002Fguardian or LAR does not provide consent\n* If the person providing informed consent needs more time than is allowed by the research design.\n* Language\u002FComprehension: Cannot understand basic English, even with literacy accommodations\n* Participation: Unwilling to comply with the Heal intervention, journaling, or questionnaires\n* Research staff will not personally use the device for research purposes. Their role is limited to facilitating device use for participants and monitoring protocol adherence.\n* While the Healpod may be available for non-research use in other settings, this protocol strictly limits its use to the described research procedures. Any non-research use will be separated from this study, and no data will be collected from individuals outside of the study.\n* Currently pregnant or becomes pregnant during the study period: If pregnant or pregnancy is discovered during participation, the individual will be withdrawn from the study to prevent any potential discomfort or unknown risk exposure related to the device environment (sound, vibration, or lighting).\n\nSpecial Exclusions\n\n* Juveniles whose participation may be influenced by coercion (e.g., enrollment tied to privileges or probation decisions)\n* Juveniles with severe cognitive or behavioral impairment that prevents safe or meaningful participation","12 Years",{"count":97,"type":21},12,[24],"Emotional dysregulation in justice-involved youth (JIY) is a condition that significantly impacts young people, their families, and juvenile justice and public health systems. Affecting an estimated 60-70% of detained Attention deficit hyperactivity disorderadolescents, it is a major driver of aggression, substance use, school failure, and later recidivism. Despite available treatments, managing emotional dysregulation in custody remains challenging, with youth often enduring high arousal, anger, and anxiety that persist into adulthood. Current popular therapies, including Cognitive Behavioral Therapy (CBT) and Dialectic Behavioral Therapy (DBT), often fall short in detention because they rely on verbal processing, require multiple scheduled sessions, and\u002For need highly trained staff. Other technologies, like biofeedback and neurostimulation techniques, are still under scrutiny for adolescents, given their higher-than-usual Adverse Events (AEs).\n\nThis SoundHeal study aims to evaluate a sensory intervention using the Healpod, a distraction-free physical space where a participant sits, delivering sound, music, gentle vibrations, and ambient light. Following this is a brief expressive journaling exercise to compare any before, during and after experience changes from the sensory immersion.\n\nThis prospective, single-center cohort study hypothesizes that these sessions will improve juveniles' ability to emotionally regulate, improve therapeutic alliance, mental health outcomes and build coping skills that can potentially help in long-term mental health and substance abuse treatment in JIY and beyond.",[101,102,103,104,105,106,29],"Emotional Dysregulation","Therapeutic Alliance","Depression Disorder","Anxiety Disorders","Stress Disorders","Substance Use Disorders",[108,109,110,111,112,113,114,115,116,117,118,119,120,121,122,123,124,125,126],"Emotional regulation","Emotional dysregulation","Justice-involved youth","Juvenile detention","Sensory-based intervention","multi-sensory stimulation therapy","Multisensory therapy","Sound therapy","music therapy","Vibroacoustic therapy","Therapeutic alliance","Therapy readiness","Mental health outcomes","substance use disorder","Coping skills","Non-verbal intervention","Journaling","Expressive Writing","Mindfulness","2026-01-16",{"date":129,"type":49},"2026-01-23",{"date":131,"type":21},"2026-01-30",{"date":133,"type":21},"2026-04",{"name":135,"class":136},"SoundHeal","INDUSTRY",{"id":138,"slug":139,"hasResults":11,"nctId":140,"briefTitle":141,"officialTitle":142,"acronym":143,"eligibilityCriteria":144,"healthyVolunteers":11,"sex":16,"minAge":63,"maxAge":4,"enrollmentInfo":145,"targetDuration":4,"studyType":22,"phases":147,"briefSummary":148,"conditions":149,"keywords":153,"overallStatus":75,"whyStopped":4,"lastUpdateSubmitDate":161,"lastUpdatePostDateStruct":162,"startDateStruct":164,"completionDateStruct":166,"leadSponsor":168,"locationsCount":86},"100618816","evaluating-the-acceptability-feasibility-and-usability-of-various-conversational-data-collection-software-100618816","NCT07336537","Evaluating the Acceptability, Feasibility and Usability of Various Conversational Data Collection Software","Evaluating the Acceptability, Feasibility and Usability of Various Digital Biopsychosocial Conversational Data Collection Software in a Patient Population With Chronic Pain","CADS","Inclusion Criteria:\n\n* Adults aged 18 years or older\n* Diagnosis of chronic pain (pain lasting 3 months or longer)\n* Able to read and understand English\n* Able to provide informed consent\n* Willing and able to complete study procedures either at home or at the MIT.nano Immersion Lab\n* Access to necessary technology for home-based participation (if assigned to home-based group), or ability to travel to the MIT.nano Immersion Lab (if assigned to laboratory-based group)\n* Cognitively able to interact with digital data collection software and provide feedback\n\nExclusion Criteria:\n\n* Under 18 years of age\n* Unable to provide informed consent\n* Non-English speaking\n* Acute pain only (pain lasting less than 3 months)\n* Cognitive impairment that would prevent meaningful interaction with data collection software or ability to provide valid feedback\n* Unable or unwilling to complete study procedures in assigned setting (home or laboratory)\n* Any condition that, in the opinion of the investigator, would make participation unsafe or interfere with the participant's ability to complete study procedures",{"count":146,"type":21},100,[24],"This research study is being conducted to evaluate digital software tools that collect health information through conversations. The study will test how acceptable, feasible, and usable these conversational software programs are for patients with chronic pain.\n\nPurpose of the Study:\n\nThe goal is to understand whether digital conversational tools can effectively gather biopsychosocial information (biological, psychological, and social factors related to health) from patients experiencing chronic pain. Biopsychosocial information includes details about your physical symptoms, emotional well-being, social circumstances, and how these factors interact to affect your health. These digital tools are designed to have conversation-like interactions with patients to collect this comprehensive health data in a more natural and engaging way.\n\nWhat Participation Involves:\n\nIf you join this study, you will interact with digital conversational software that will ask you questions about your health, pain experience, and related factors. The software is designed to communicate with you in a conversational manner, similar to talking with a healthcare provider, to gather information about your condition. You will be asked about various aspects of your chronic pain experience, including how it affects your daily life, your emotional state, and your social interactions.\n\nWho Can Participate:\n\nThis study is looking for participants who have chronic pain conditions. Medical providers who treat patients with chronic pain are encouraged to refer eligible patients to this study. Healthcare providers interested in referring patients or learning more about the study can contact the study sponsor, AugMend Health Inc.\n\nWhy This Research Matters:\n\nChronic pain affects millions of people and understanding the full scope of how it impacts patients requires collecting detailed information about physical, psychological, and social factors. Traditional methods of collecting this information can be time-consuming and may not capture the complete picture. Digital conversational tools offer a potential new approach to gathering comprehensive health information in a more efficient and patient-friendly manner. This research will evaluate whether patients find these tools acceptable to use, whether they work practically in real-world clinical settings, and whether they are user-friendly and accessible for people with chronic pain.\n\nStudy Location:\n\nThe study is being conducted at AugMend Health in Cambridge, Massachusetts.\n\nStudy Sponsor:\n\nThis study is sponsored by AugMend Health Inc. Healthcare providers or potential participants who would like more information about the study or wish to make a referral can contact AugMend Health Inc.\n\nParticipation in this study is voluntary, and you can choose to stop participating at any time without affecting your regular medical care.",[150,29,151,152],"Chronic Pain","Behavioral Health Challenges","Ecological Momentary Assessment Best Practices",[150,154,155,156,157,158,159,160],"Behavioral Health","Mental Health","Technology","Assessment","Data Collection","Biopsychosocial","Digital Health","2025-12-30",{"date":163,"type":49},"2026-01-13",{"date":165,"type":49},"2025-10-03",{"date":167,"type":21},"2026-07-31",{"name":169,"class":136},"AugMend Health Inc.",{"id":171,"slug":172,"hasResults":11,"nctId":173,"briefTitle":174,"officialTitle":174,"acronym":4,"eligibilityCriteria":175,"healthyVolunteers":11,"sex":16,"minAge":63,"maxAge":176,"enrollmentInfo":177,"targetDuration":4,"studyType":22,"phases":179,"briefSummary":180,"conditions":181,"keywords":4,"overallStatus":75,"whyStopped":4,"lastUpdateSubmitDate":182,"lastUpdatePostDateStruct":183,"startDateStruct":185,"completionDateStruct":187,"leadSponsor":189,"locationsCount":86},"100600497","decide-to-improve-maternal-mental-health-care-delivery-100600497","NCT07098260","DECIDE to Improve Maternal Mental Health Care Delivery","Inclusion Criteria:\n\n* Perinatal or mental health care providers who currently provide perinatal mental health care within health systems\n* Ages between 18 and 64\n* Must be able to understand the training content in English and comfortably complete the assessments and share feedback in English\n\nExclusion Criteria:\n\n* Healthcare providers who do not practice as part of a healthcare system\n* Healthcare providers who do not practice in the U.S.\n* Healthcare providers who do not currently provide perinatal mental health care","64 Years",{"count":178,"type":21},35,[24],"Appropriate training for perinatal mental health care is an important public health concern as mental health disorders are common pregnancy complications. Perinatal and mental health care providers report the difficulty of treating perinatal individuals due to insufficient information available regarding mental health treatment decisions, differences in beliefs and attitudes, and concerns about adverse effects on patients, such as self-harm and suicide. Effective shared decision-making skills can improve perinatal and mental health care providers' competencies to meet the unique decision needs of perinatal individuals, particularly those with mental health disorders. The proposed project titled \"DECIDE to Improve Maternal Mental Health Care Delivery\" aims to adapt the DECIDE Provider Training developed by Dr. Alegria and her team,1 to improve the rapid and wide dissemination and implementation of DECIDE in meeting the mental health needs of perinatal individuals. DECIDE stands for Decide the problem; Explore the questions; Closed or open-ended questions; Identify the who, why, or how of the problem; Direct questions to your health care professional; Enjoy a shared solution. The DECIDE provider training was developed based on theories of intergroup contact in social psychology and a patient-centered framework.28-30 DECIDE teaches mental health providers how to improve perspective-taking, reduce attributional errors, and increase receptivity to the client population.1,15-17 The proposed project will (1) make content adaptation (i.e., adding topical training content to fit perinatal mental health care) and process adaption (i.e., creating asynchronous training modules to reduce the burden for care providers) to the DECIDE Provider Training and (2) assess the acceptability, appropriateness, and usability of adapted DECIDE provider training for rapid and wide dissemination and implementation of DECIDE in maternal mental health care delivery.",[29],"2025-10-30",{"date":184,"type":49},"2025-11-03",{"date":186,"type":49},"2025-02-14",{"date":188,"type":21},"2026-12-31",{"name":190,"class":85},"Rutgers, The State University of New Jersey",{"id":192,"slug":193,"hasResults":11,"nctId":194,"briefTitle":195,"officialTitle":196,"acronym":4,"eligibilityCriteria":197,"healthyVolunteers":15,"sex":16,"minAge":63,"maxAge":4,"enrollmentInfo":198,"targetDuration":200,"studyType":201,"phases":4,"briefSummary":202,"conditions":203,"keywords":4,"overallStatus":75,"whyStopped":4,"lastUpdateSubmitDate":210,"lastUpdatePostDateStruct":211,"startDateStruct":213,"completionDateStruct":215,"leadSponsor":217,"locationsCount":86},"100601160","non-interventional-pre-screening-protocol-aims-to-evaluate-participants-for-potential-trial-eligibility-in-future-clinical-trialsstudies-focusing-on-metabolic-and-psychiatric-health-100601160","NCT07106879","Non-interventional Pre-screening Protocol Aims to Evaluate Participants for Potential Trial Eligibility in Future Clinical Trials\u002FStudies Focusing on Metabolic and Psychiatric Health.","Pre-screening Survey for Metabolic, Cardiovascular, Obesity, Mental Health, and Endocrine Trial Eligibility (DOVE-MET-COME-100)","Inclusion Criteria:\n\n* Any participant of age 18 years and over\n* Who are willing to provide informed consent and participate in the pre-screening study and comply with study procedures.\n\nExclusion Criteria:\n\n* Pregnant or breastfeeding individuals\n* Individuals having severe cognitive impairment or inability to provide informed consent\n* Individuals having acute psychiatric emergencies requiring immediate intervention\u002Fhospitalization\n* Individuals who are currently participating in another research study that conflicts with pre-screening data collection\n* Individuals having known history of drug\u002Falcohol misuse\n* Individuals having medical conditions that, in the investigator's opinion, could compromise the integrity of the screening process or pose significant risks to the participant's health.",{"count":199,"type":21},7000,"5 Years","OBSERVATIONAL","DOVE-MET-COME-100 is a single site prescreening survey study designed to identify adults who may be eligible for future industry-sponsored clinical trials. A physician will oversee the informed consent process, after which participants will be surveyed on demographics, medical history, current health conditions and symptoms. The study team may also collect basic health information, including vital signs, urine drug tests, blood samples and pregnancy tests (if applicable). A physician will review each participant's medical history in a one-on-one interview to assess potential fit for upcoming trials. If needed, the doctor may contact the participant's current doctors or pharmacies to gather more information for eligibility review.",[27,204,205,206,29,207,208,209],"Metabolic Syndrome","Obesity","Prediabetes","Endocrine Dysfunction","Type 2 Diabetes Mellitus (T2DM)","Chronic Kidney Disease (CKD)","2025-08-11",{"date":212,"type":49},"2025-08-12",{"date":214,"type":49},"2025-07-30",{"date":216,"type":21},"2030-12-01",{"name":218,"class":85},"Clindove Research LLC"]