[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"mental-health-literacy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:mental-health-literacy":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,11,0,[8,47,81,105,128,156,189,231,253,278,300],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":4},"100644227","psychosocial-support-program-for-public-school-teachers-100644227",false,"NCT07666542","Psychosocial Support Program for Public School Teachers","Evaluation of the Effectiveness and Feasibility of Different Formats of a School-Based Psychosocial Support Program for Public School Teachers: A Randomized Clinical Trial","PSP","Inclusion Criteria:\n\nSchool-level inclusion criteria:\n\n* Public schools from the state education system of Rio Grande do Sul, Brazil, serving students in \"Ensino Fundamental\" and \"Ensino Médio\" (equivalent to grades 1-12), and belonging to \"Polo 1\", an administrative grouping defined by the Rio Grande do Sul State Department of Education that includes the following Regional Education Coordinators (Coordenadorias Regionais de Educação \\[CREs\\]): 1st, 2nd, 11th, 12th, 27th, and 28th CREs;\n* Schools with 10 or more teachers on staff;\n* Schools with a complete school management team, defined as having all three core management roles in place.\n\nParticipant-level inclusion criteria (teacher level)\n\nParticipating teachers must meet all of the following criteria:\n\n* Teachers currently working in participating public schools;\n* Able and willing to participate in all stages of the intervention and scheduled assessments;\n* Provide informed consent prior to participation\n\nExclusion Criteria:\n\nSchool-level exclusion criteria:\n\n* Schools with fewer than 10 teachers on staff;\n* Schools without a complete school management team;\n* Youth and Adult Education Centers (Núcleos de Educação de Jovens e Adultos \\[EJA\\]);\n* Schools that began operating as full-time schools in 2026;\n* Schools not belonging to Polo 1 of the state education system of Rio Grande do Sul;\n* Schools that do not serve students in grades 1-12\n\nParticipant-level exclusion criteria\n\n* Not currently working as a teacher in a participating public school;\n* Unable to participate in the training in the planned date for the specific school the teacher works at;\n* Decline or are unable to provide informed consent","ALL",{"count":19,"type":20},2925,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this clinical trial is to learn if different formats of a school-based psychosocial support training program can improve teachers' ability to recognize and respond to students' mental health needs. The study will include teachers working in public schools in Brazil.\n\nThe main questions it aims to answer are:\n\n1. Do teachers who receive the training improve their knowledge on how to better to identify and support students with mental health difficulties?\n2. Do different formats of training (in-person, online, or self-paced) and the presence of supervision lead to different levels of improvement in this knowledge, in attitudes related to mental health, and helping behaviors?\n\nResearchers will compare five versions of the program (in-person, online, and asynchronous formats, with or without supervision) to see which approach is more effective, acceptable, and feasible.\n\nParticipants will:\n\n1. Take part in a training program delivered either in-person, online, or through self-paced materials;\n2. In some groups, attend additional supervision sessions to discuss real-life cases;\n3. Receive brief follow-up materials through mobile messages after the training\n4. Complete online questionnaires at multiple time points (before the training, during the program, after completion, and at follow-up).\n\nThe study will measure changes in teachers' knowledge, attitudes, and behaviors related to supporting students' mental health, as well as satisfaction with the program and its feasibility for large-scale implementation.",[26,27],"Mental Health Literacy","School Mental Health Training of Teachers",[29,30,31,32,33,34],"School Mental Health","Psychosocial Support","Cluster Randomized Controlled Trial","Teacher Professional Development","Mental Health Promotion","Education Policy","NOT_YET_RECRUITING","2026-06-22",{"date":38,"type":39},"2026-06-24","ACTUAL",{"date":41,"type":20},"2026-06-29",{"date":43,"type":20},"2026-12-16",{"name":45,"class":46},"Hospital de Clinicas de Porto Alegre","OTHER",{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":53,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":21,"phases":56,"briefSummary":57,"conditions":58,"keywords":63,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":80},"100589498","youth-for-youth-mental-wellness-care-and-action-100589498","NCT06955195","Youth-for-Youth Mental Wellness Care and Action","Inclusion Criteria:\n\n* student in Hong Kong secondary school\n* Studying at Form 1 to Form 3 at the time of recruitment\n* Competence in comprehending written Chinese or English\n* Competence in speaking Cantonese or English\n* Written consent from students and their legal guardian\n\nExclusion Criteria:\n\n* Not studying at Form 1 to 3 in Hong Kong secondary school\n* Incompetence in comprehending written Chinese or English\n* Incompetence in speaking Cantonese or English\n* No written consent from students or their legal guardian",true,{"count":55,"type":20},18000,[23],"This initiative aims to improve flourishing and quality of life of secondary school students, reduce mental distress (e.g., depression and suicidal ideation), enhance their understanding of mental health (e.g., mental health literacy) and help-seeking intention, and foster a supportive school environment (e.g., school climate-caring relationship, and sense of community). Also, this initiative aims to improve students' process of change in psychological (e.g., mattering, emotion regulation, empowerment) and social (e.g., trust belief) aspects and mental health awareness (e.g., mental health stigma). The feasibility, acceptability, and sustainability of the programme from multiple perspectives (e.g., students, student leaders, and stakeholders) will also be evaluated. In addition, the cost-effectiveness of delivering this programme (e.g., the incremental cost-effectiveness ratio (ICER)) among secondary schools in Hong Kong will be assessed.\n\nThe programme will be implemented among students in 130 local secondary schools over three academic years. The first is a pilot phase (Year 1), which 40 schools will implement the intervention and student participants will be evaluated at pre- (T0) and post-intervention (T1) using questionnaires. In this stage, participatory research will be conducted before and after the intervention among students, student leaders, and stakeholders in 20 pilot schools to co-design the intervention, ensuring the programme meet the actual wellness needs of youth. In following two academic years, an additional 90 schools will participate in a cluster randomized controlled trial (RCT) with a 1:1 ratio between intervention and waitlist control groups. Each year, 45 schools will implement the intervention. Summative evaluation will be conducted among RCT schools at T0 and T1, and 3-month follow-up (T2). Quantitative data be collected to assess the effectiveness of intervention, and qualitative data will provide understanding of students' and stakeholders' perspectives of the intervention implementation. Cost outcomes will include intervention costs and cost savings, calculated from the payer (i.e., JC\u002Fgovernment) perspective using administrative records or validated tools. The primary outcome of cost-effectiveness will be the quality-adjusted life-years (QALYs) of students. Cost of implementing the intervention program and QALYs will be used to evaluate the cost-effectiveness of the intervention, for example, estimate the incremental cost-effectiveness ratio (ICER).",[59,60,26,61,62],"Mental Well-being","Adolescent Health","School Difficulties Associated With Mental Health Problems","Mental Health Help-Seeking",[64,65,66,67,68,69],"MENTAL HEALTH","ADOLESCENT MENTAL HEALTH","SCHOOL CLIMATE ON MENTAL HEALTH","MENTAL HEALTH FRIENDLY CAMPUS","MENTAL HELP-SEEKING BEHAVIOR","MENTAL HEALTH LITERACY","RECRUITING","2026-05-27",{"date":73,"type":39},"2026-05-29",{"date":75,"type":39},"2025-08-21",{"date":77,"type":20},"2027-12-31",{"name":79,"class":46},"Chinese University of Hong Kong",2,{"id":82,"slug":83,"hasResults":11,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":4,"eligibilityCriteria":87,"healthyVolunteers":53,"sex":17,"minAge":88,"maxAge":4,"enrollmentInfo":89,"targetDuration":4,"studyType":21,"phases":91,"briefSummary":92,"conditions":93,"keywords":94,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":104},"100636357","roots-for-life-project-strengthening-mental-health-in-school-communities-100636357","NCT07564635","Roots for Life Project: Strengthening Mental Health in School Communities","Pilot Study of a Mental Health Literacy-Based Intervention for Parents and Teachers to Improve the Mental Health of Children in 3rd to 5th Grade in Chile and Ecuador","Inclusion Criteria:\n\nChildren Participants:\n\n* Child is enrolled in 3rd, 4th, or 5th grade of primary school\n* Child is under 12 years of age\n* Child's parent or legal guardian has provided written informed consent\n* Child attends a participating public or subsidized school in Valparaíso, Achao, Curaco de Vélez (Chile), or Daule (Ecuador)\n\nTeachers:\n\n* Works as a teacher in a participating school\n* Teaches students in first or second cycle of primary education (grades 1-6)\n* Voluntarily agrees to participate in the study\n\nParents\u002FCaregivers:\n\n* Is the parent or caregiver of a child under 12 years of age\n* Child is enrolled in 3rd, 4th, or 5th grade of primary school\n* Voluntarily agrees to participate in the study\n\nExclusion Criteria:\n\nChildren Participants:\n\n\\- Child has sensory problems or physical disabilities that prevent completion of surveys\n\nTeachers:\n\n* Works as educational assistant or in administrative functions only\n* Voluntarily declines to participate in the study\n\nParents\u002FCaregivers:\n\n* Child has sensory problems or physical disabilities that prevent completion of surveys\n* Voluntarily declines to participate in the study","5 Years",{"count":90,"type":20},200,[23],"This pilot study, titled \"Roots for Life Project: Strengthening Mental Health in School Communities\", aims to evaluate the feasibility and preliminary effectiveness of a mental health literacy (MHL) intervention for teachers and parents to improve the mental health of children aged 8-11 years (3rd to 5th grade) in primary schools located in socially vulnerable areas of Chile and Ecuador.\n\nChild mental health problems represent a major burden worldwide, with high prevalence and a treatment gap exceeding 70% in Latin America. Schools and families play a key role in early detection, yet both often lack the necessary knowledge and confidence to identify mental health difficulties or seek appropriate help. Increasing mental health literacy-defined as knowledge and beliefs that support recognition, management, and prevention of mental health problems-has proven to enhance early help-seeking, reduce stigma, and promote wellbeing.\n\nThe project builds upon the prior Chilean FONIS Project SA21I0143, which tested a teacher-focused MHL program and demonstrated improvements in teachers' knowledge, reduced depressive symptoms, and lower burnout levels. The current study extends this work by (1) adding a parent-focused component, (2) evaluating outcomes in children, and (3) implementing the program in two countries to assess cross-cultural feasibility.\n\nThis quasi-experimental study will include seven primary schools-five in Chile (Valparaíso, Achao, Curaco de Vélez) and two in Ecuador (Daule). Schools will be randomly assigned within each locality to either intervention or control conditions. Approximately 230 children, their parents\u002Fguardians, and teachers will participate. Assessments will be conducted before and after the intervention using validated instruments.\n\nThe teacher program consists of six 2-hour participatory workshops covering topics such as self-care, child development, anxiety and depression, suicide prevention, behavioral disorders, autism, and child maltreatment. The parent program includes three 90-minute educational sessions addressing stigma, social support, healthy development, and emotional containment. Both components emphasize experiential learning and culturally adapted materials.\n\nPrimary outcome:\n\nMental health literacy among parents and teachers (MHL Scale).\n\nSecondary outcomes:\n\nPsychological wellbeing of adults (GHQ-12).\n\nChronic stress levels in children (cortisol in fingernails).\n\nAdverse childhood experiences (ACE questionnaire).\n\nImplementation indicators (acceptability, satisfaction, barriers, facilitators).\n\nQuantitative analyses will compare pre- and post-intervention outcomes and calculate effect sizes. Mediation and moderation models will explore relationships among child, family, and school-level variables. Qualitative data from focus groups with parents and teachers will complement these findings to evaluate feasibility and contextual adaptations.",[26],[26],"2026-04-26",{"date":97,"type":39},"2026-05-04",{"date":99,"type":39},"2025-03-01",{"date":101,"type":20},"2026-07-31",{"name":103,"class":46},"Universidad de Valparaiso",3,{"id":106,"slug":107,"hasResults":11,"nctId":108,"briefTitle":109,"officialTitle":110,"acronym":4,"eligibilityCriteria":111,"healthyVolunteers":53,"sex":17,"minAge":112,"maxAge":4,"enrollmentInfo":113,"targetDuration":4,"studyType":21,"phases":115,"briefSummary":116,"conditions":117,"keywords":4,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":119,"lastUpdatePostDateStruct":120,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":126,"locationsCount":80},"100522787","promoting-mental-health-of-teachers-and-caregiver-using-a-personalized-mhealth-toolkit-in-uganda-100522787","NCT06087159","Promoting Mental Health of Teachers and Caregiver Using a Personalized mHealth Toolkit in Uganda","Promoting Mental Health of Teachers and Caregivers Using a Personalized mHealth Toolkit in Uganda","Teachers Inclusion Criteria:\n\n* Teaching in recruited schools.\n* At least 18 years old.\n\nParents Inclusion Criteria:\n\n* At least 18 years old.\n* Have a child aged 6-14 years.\n\nExclusion Criteria:\n\n* Evidence of psychopathology or cognitive impairment severe enough to preclude giving consent, or completing the survey instruments or the focus group of the study.\n* Parents\u002FTeachers\u002FCaregivers who are not in one of our recruited primary school\n* Participants under the age of 18\n* Participant who does not speak English and Luganda will not be able to participate","18 Years",{"count":114,"type":20},1180,[23],"This study record describes a two-phase of clinical trial study. The first phase is a pilot study phase (to study feasibility and efficacy of the intervention), and the second phase is an effectiveness study phase (a fully powered evaluation study to test the intervention effectiveness). This proposal seeks to develop and test a new mHealth intervention, the mHealth Toolkit for Wellness \\& Empowering Lives of School Community (mWEL) in Uganda. The mWEL-digial toolkit is a preventive intervention tool for teachers and parents as a self-help support modality. Caregivers who need support in navigating the toolkit will be supported by peer-community health workers (P-CHWs).",[26,118],"Depression, Anxiety","2026-04-16",{"date":121,"type":39},"2026-04-20",{"date":123,"type":39},"2024-11-01",{"date":125,"type":20},"2028-01-31",{"name":127,"class":46},"NYU Langone Health",{"id":129,"slug":130,"hasResults":11,"nctId":131,"briefTitle":132,"officialTitle":133,"acronym":4,"eligibilityCriteria":134,"healthyVolunteers":53,"sex":17,"minAge":135,"maxAge":112,"enrollmentInfo":136,"targetDuration":4,"studyType":21,"phases":138,"briefSummary":139,"conditions":140,"keywords":145,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":147,"lastUpdatePostDateStruct":148,"startDateStruct":150,"completionDateStruct":152,"leadSponsor":154,"locationsCount":4},"100623331","mental-health-literacy-and-help-seeking-behavior-among-adolescents-100623331","NCT07395245","Mental Health Literacy and Help-Seeking Behavior Among Adolescents","Mental Health Literacy and Help-Seeking Behavior Among Adolescents in Assiut City: An Interventional Study","Inclusion Criteria:\n\n* Adolescents aged 13-18 years.\n* Enrolled in selected schools in Assiut city\n\nExclusion Criteria:\n\n* Documented severe intellectual disability or learning difficulty that, in the judgement of school staff, would prevent understanding of the intervention content or valid questionnaire completion.\n* Current acute medical or psychiatric emergency at the time of data collection as identified by school or health-center staff.\n* Refusal of participation by the student, or absence of parental consent.","13 Years",{"count":137,"type":20},150,[23],"This study examines mental health awareness and help-seeking behaviors among adolescents aged 13-18 years in Assiut City, Egypt. Mental health problems are common among young people, but many adolescents do not seek professional help when they need it. This is often due to low mental health literacy (not understanding mental health problems or knowing where to get help), stigma (negative attitudes toward mental illness), and fears about confidentiality or being judged.\n\nThe study has two parts:\n\nPart 1 - Assessment Phase: Researchers will survey approximately 270 students from preparatory and secondary schools in Assiut to understand their current levels of mental health literacy, stigma, and willingness to seek help for mental health problems. Students will complete validated questionnaires that measure their knowledge about mental health, their attitudes toward peers with mental health problems, and their intentions to seek help from various sources.\n\nPart 2 - Intervention Phase: In a randomized controlled trial involving 150 students (75 in an intervention group and 75 in a control group), researchers will test whether a brief educational program can improve mental health literacy, reduce stigma, and increase help-seeking intentions. The intervention consists of three weekly classroom sessions covering: (1) mental health literacy - basic concepts, common problems in adolescents like stress and anxiety, recognizing symptoms; (2) stigma reduction - understanding how negative labels hurt people, recognizing public and self-stigma, using respectful language; and (3) help-seeking behavior - knowing when to seek help, understanding formal and informal help sources, overcoming barriers, and learning about local resources in Assiut.\n\nStudents in both groups will complete questionnaires before the intervention and one month after completion. The control group will not receive the educational sessions during the study period. Researchers will compare changes in mental health knowledge, stigma levels, and help-seeking attitudes between the two groups to determine whether the program is effective.\n\nThe study aims to address a critical gap in mental health services for adolescents in Upper Egypt by improving young people's understanding of mental health and encouraging them to seek appropriate help when needed.",[141,26,142,143,144],"Mental Health","Stigma of Mental Illness","Help-Seeking Behavior","Adolescent Mental Health",[26,143,144,146],"Stigma","2026-02-02",{"date":149,"type":39},"2026-02-09",{"date":151,"type":20},"2026-05",{"date":153,"type":20},"2027-06",{"name":155,"class":46},"Assiut University",{"id":157,"slug":158,"hasResults":11,"nctId":159,"briefTitle":160,"officialTitle":161,"acronym":162,"eligibilityCriteria":163,"healthyVolunteers":53,"sex":17,"minAge":164,"maxAge":165,"enrollmentInfo":166,"targetDuration":4,"studyType":21,"phases":167,"briefSummary":168,"conditions":169,"keywords":172,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":180,"lastUpdatePostDateStruct":181,"startDateStruct":183,"completionDateStruct":185,"leadSponsor":187,"locationsCount":4},"100617872","pilot-cluster-rct-of-an-indirect-contact-mental-health-literacy-program-for-5th-grade-students-100617872","NCT07324265","Pilot Cluster RCT of an Indirect Contact Mental Health Literacy Program for 5th-Grade Students","A Cluster-Randomized Pilot Trial of a School-Based Mental Health Literacy Program With and Without an Indirect Contact Component for 5th-Grade Students","SMHLP-IC","Inclusion Criteria:\n\n* Students enrolled in 5th grade at one of the eight participating public elementary schools in Kanazawa, Japan.\n* Aged 10-11 years old.\n* Passive consent obtained from guardians; verbal assent obtained from children.\n* Able to complete self-report questionnaires.\n\nExclusion Criteria:\n\n* Students whose parents\u002Fguardians opted out of the study.\n\nNote: Students who were absent on the day of the pre-test (T1) were excluded from the analysis population but not from the initial study cohort.","10 Years","11 Years",{"count":137,"type":20},[23],"This cluster-randomized pilot trial will evaluate the preliminary effects and feasibility of adding an indirect contact component to a school-based mental health literacy (MHL) lesson for 5th-grade students in a public elementary school in Tokyo, Japan. Four 5th-grade classes (approximately 150 students in total) will be randomized by class (two classes per arm). All students will receive a 45-minute lesson that includes an animated video and educational slides. In the intervention arm, teachers will additionally introduce a short story about a well-known soccer player who experienced and recovered from a mental health condition, serving as an indirect contact element. The control arm will receive the standard lesson without this component.\n\nStudents will complete questionnaires at baseline (T1), immediately after the lesson (T2), and 2-3 months later (T3). The primary outcome is vignette-based social distance toward a peer with mental health problems. Secondary outcomes include mental health knowledge, help-seeking intentions, perceived need for help, intended sources of help. As a pilot study with only four clusters, the trial is not powered to detect small effects; findings will be used to estimate effect sizes and assess feasibility for a future larger-scale trial.",[26,170,171],"Stigma (Social Distance)","Help-seeking Intention",[173,174,175,176,177,178,179],"Mental health literacy","Stigma reduction","Indirect contact","Social distance","Help-seeking intentions","School-based intervention","Elementary school students","2025-12-22",{"date":182,"type":39},"2026-01-07",{"date":184,"type":20},"2025-12-15",{"date":186,"type":20},"2026-08-30",{"name":188,"class":46},"Tokyo University",{"id":190,"slug":191,"hasResults":11,"nctId":192,"briefTitle":193,"officialTitle":193,"acronym":194,"eligibilityCriteria":195,"healthyVolunteers":53,"sex":17,"minAge":112,"maxAge":4,"enrollmentInfo":196,"targetDuration":4,"studyType":21,"phases":198,"briefSummary":199,"conditions":200,"keywords":210,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":222,"lastUpdatePostDateStruct":223,"startDateStruct":225,"completionDateStruct":227,"leadSponsor":229,"locationsCount":80},"100611237","cocreating-action-to-improve-rationality-in-the-health-system-100611237","NCT07237971","Cocreating Action to Improve Rationality in the Health System","CAIR","Survey general population:\n\nA representative population survey of adult (aged 18 years and over) who are residents in the Municipal District 2 of Elche (Spain).\n\nSurvey community pharmacies:\n\nIndividuals who visit the pharmacies collaborating in the Municipal District 2 of Elche (Spain) to obtain any of the medications, aged 18 years and over for three a priori established medication groups.\n\n* Group 1 (Antidepressants and Anxiolytics): N05B, N05C, N06A.\n* Group 2 (Cardiovascular disease risk factor medication): A10B (antidiabetics), C10A (cholesterol-lowering drugs), C07A, C09A, C03C, C08C (antihypertensives).\n* Group 3 (Antibiotics): J01\n\nHealth service data from primary care:\n\nA series of aggregate indicators will be collected from the electronic information systems of the regional health authorities (Conselleria de Sanidad de la Generalitat Valenciana), which hosts information on both prescriptions made by physicians and those dispensed in the community pharmacies of the Valencian Community. These indicators will be calculated for individuals aged 18 years and over for groups 2 and 3, and 12 years and over for group 1 using aggregate data from health system's registries and, therefore, not considering 12 years old as minimum age limit of the eligible participants in the present study protocol registry. Furthermore, aggregate data about the number of consultations will be collected in the two primary care facilities in the study area for individuals aged 18 and over.\n\nQualitative methods and cocreation procedure:\n\nFocus groups, sociograms and in-depth interviews will include 6-8 participants and last approximately 90 minutes. Participation in the co-creation process will be open, voluntary, and will depend on the interest of individuals and entities in the area. Eligibility criteria:\n\n* People aged 18 and over who are residents or have a job or family connection in the Municipal District 2 of Elche (Spain) who are interested in participating, wish to be actively involved in the co-creation, planning, and implementation of community initiatives, and are available to attend the conferences, meetings, and workshops.\n* Representatives from community institutions and associations, including professionals from the Elche Public Health Center, primary care teams in the area, Elche Council staff, as well as professionals and volunteers from NGOs and other local organizations with experience in community work in the district.",{"count":197,"type":20},4000,[23],"Despite widespread recognition of social, economic, or environmental health determinants, health action remains heavily dominated by individual-level solutions (e.g., medication, patient counselling, vaccination). This study aims to stimulate changes in health system functioning by demonstrating how the cocreation of actions to address psychological well-being, cardiovascular health, and antimicrobial resistance from within the community can alleviate the burden on primary care services, reduce medicalisation and increase health equity.\n\nThe scientific approach uses mixed methods and incorporates theory from multiple disciplines. This study will appraise how the current system addresses psychological well-being, cardiovascular (CV) health, and rational use of antibiotics using a population survey, a survey of patients collecting their medication at community pharmacies, aggregate health service indicators on medication consumption and primary care consultations, and qualitative methods exploring stakeholders' perceptions.The investigators will undertake community-based participatory research to engage citizen scientists in the cocreation of community-led actions to promote psychological well-being, CV health, and prevent antimicrobial resistance. The design, implementation, and evaluation of the actions will apply an assets-based approach and apply theories and frameworks from implementation science in an iterative manner over 3 years. Finally, the impact of the cocreated actions will be analysed, considering effectiveness and broader contextual issues such as initiative adoption, implementation, and maintenance. The investigators will use a before-after comparison of survey indicators, an interrupted time-series analysis of health service data and qualitative analysis.\n\nThe goal is to demonstrate how the integration of community action with attention to the social determinants of health, can lead to a more rational approach to health care and ultimately improve health and health equity.",[201,202,203,204,205,26,206,207,208,209],"Health-Related Quality-of-Life","Social Capital","Health Literacy","Community Based Participatory Research","Antibiotic Prescription","Cardio Vascular Disease","Antimicrobial Drug Resistance","Well-being","Health Equity",[211,212,213,214,215,216,217,218,219,220,221],"Community health","Cocreation action","Health system","Health literacy","Social capital","Community capital","Antibiotic drug use","Cardiovascular drug use","Psychotropic drug use","Health-related quality of life","Health equity","2025-11-24",{"date":224,"type":39},"2025-12-02",{"date":226,"type":39},"2025-10-21",{"date":228,"type":20},"2029-04-01",{"name":230,"class":46},"Universidad Miguel Hernandez de Elche",{"id":232,"slug":233,"hasResults":11,"nctId":234,"briefTitle":235,"officialTitle":236,"acronym":4,"eligibilityCriteria":237,"healthyVolunteers":53,"sex":17,"minAge":165,"maxAge":112,"enrollmentInfo":238,"targetDuration":4,"studyType":21,"phases":240,"briefSummary":241,"conditions":242,"keywords":4,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":243,"lastUpdatePostDateStruct":244,"startDateStruct":246,"completionDateStruct":248,"leadSponsor":250,"locationsCount":252},"100611304","non-inferiority-of-virtual-vs-traditional-methods-in-adolescent-mental-health-literacy-100611304","NCT07238842","Non-inferiority of Virtual vs. Traditional Methods in Adolescent Mental Health Literacy","A Non-inferiority Study of the Virtual Agent-based Versus Teacher-led Psychological Literacy Enhancement Method in Improving Adolescents' Mental Health Literacy","Inclusion Criteria:\n\n1. Age between 11 and 18 years inclusive.\n2. Able to fluently operate a computer or smartphone.\n3. Possess normal language expression and reading comprehension abilities.\n4. Voluntarily agree to participate in the study and provide signed informed consent (and parental consent where required by local regulations).\n\nExclusion Criteria:\n\n1. Diagnosed with a psychiatric disorder that impairs the ability to complete assessments or participate in the intervention.\n2. Suffering from a severe physical illness, central nervous system disease, or substance use disorder that could interfere with study participation or outcomes.",{"count":239,"type":20},360,[23],"The goal of this clinical trial is to determine whether a digital psychological literacy program delivered by an AI-powered virtual agent is non-inferior to traditional teacher-led instruction in improving mental health literacy among adolescents. The study focuses on middle and high school students aged 11 to 18 years attending a school in Shanghai, China, including those with varying levels of emotional well-being but excluding those with diagnosed psychiatric disorders or severe physical illness.\n\nThe main questions it aims to answer are:\n\nIs the virtual agent-delivered psychological literacy program as effective as teacher-led instruction in improving adolescents' mental health literacy? Does the virtual agent intervention lead to comparable or better outcomes in secondary measures such as depression, anxiety, psychological resilience, sleep quality, and digital well-being?\n\nResearchers will compare students receiving 6 weekly sessions from a virtual digital agent to students receiving the same curriculum delivered by trained psychology teachers to see if the AI-based approach achieves similar improvements in mental health knowledge, attitudes, and help-seeking behaviors.\n\nParticipants will:\n\nComplete online assessments at baseline, week 3, week 6 and week 18 covering mental health literacy (UMHL-A), depression (PHQ-9), anxiety (GAD-7), psychological resilience (RSCA), and other well-being indicators Attend one 45-60 minute session per week for 6 weeks, either interacting with the virtual agent or participating in a teacher-led class Optionally take part in a brief satisfaction survey and\u002For a focus group interview after the intervention to share their experiences",[26],"2025-11-16",{"date":245,"type":39},"2025-11-20",{"date":247,"type":39},"2025-05-16",{"date":249,"type":20},"2026-02-28",{"name":251,"class":46},"Shanghai Mental Health Center",1,{"id":254,"slug":255,"hasResults":11,"nctId":256,"briefTitle":257,"officialTitle":258,"acronym":259,"eligibilityCriteria":260,"healthyVolunteers":11,"sex":17,"minAge":112,"maxAge":4,"enrollmentInfo":261,"targetDuration":4,"studyType":21,"phases":263,"briefSummary":264,"conditions":265,"keywords":4,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":269,"lastUpdatePostDateStruct":270,"startDateStruct":272,"completionDateStruct":274,"leadSponsor":276,"locationsCount":252},"100551182","text-messaging-intervention-to-support-parents-after-their-childs-psychiatric-emergency-100551182","NCT06456762","Text-messaging Intervention to Support Parents After Their Child's Psychiatric Emergency","Developing and Testing a Text-messaging Intervention to Support Parents After Their Child's Psychiatric Emergency","iPEACE","Inclusion Criteria:\n\n* Parents or legal guardians of a child ages 11-17;\n* Parents or legal guardians must live with their child ≥50% of the time;\n* Child must be admitted to the pediatric emergency department for a mental health crisis;\n* Child must be discharged home from the emergency department with referrals to outpatient care.\n\nExclusion Criteria:\n\n* Do not have daily access to a mobile phone that can receive SMS text messages;\n* Do not speak and read fluently in English.",{"count":262,"type":20},90,[23],"This grant aims to develop and test a text-messaging intervention for parents of children and teens evaluated in the emergency department for a psychiatric emergency and discharged home with outpatient referrals. The intervention for parents will teach parents skills to navigate the mental health services system and build their self-efficacy in managing their child's mental health. This research has the potential to improve services for families seeking emergency psychiatric support, with the goal of facilitating treatment engagement and reducing emergency services utilization using scalable, cost-effective, accessible tools.",[266,267,26,268],"Parents","Self Efficacy","Psychiatric Emergency","2025-11-05",{"date":271,"type":39},"2025-11-10",{"date":273,"type":39},"2024-08-01",{"date":275,"type":20},"2026-12-31",{"name":277,"class":46},"Vanderbilt University Medical Center",{"id":279,"slug":280,"hasResults":11,"nctId":281,"briefTitle":282,"officialTitle":283,"acronym":4,"eligibilityCriteria":284,"healthyVolunteers":53,"sex":17,"minAge":165,"maxAge":112,"enrollmentInfo":285,"targetDuration":4,"studyType":21,"phases":287,"briefSummary":288,"conditions":289,"keywords":290,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":292,"lastUpdatePostDateStruct":293,"startDateStruct":295,"completionDateStruct":296,"leadSponsor":298,"locationsCount":252},"100569397","sanctuary-youth-series-randomized-control-trial-100569397","NCT06693713","Sanctuary Youth Series Randomized Control Trial","The Youth Series Sanctuary Mental Health Ministries Randomized Control Trial","Inclusion Criteria:\n\n* Youth between the ages of 11-18 attending a youth group that has been recruited to the study.\n\nExclusion Criteria:\n\n* Youth outside of the age range that are not attending a youth group recruited to the study.",{"count":286,"type":20},2000,[23],"Sanctuary Mental Health Ministries designed an eight-week program for youth ages 11-15 that uses games, short films, discussion questions, and exercises to engage with mental health and faith topics. The intervention package includes a facilitation guide and a guide for parents and caregivers. The program is intended to be conducted by an experienced facilitator, although there is no specific training provided for facilitators outside of the facilitation guide. The facilitator would lead groups of 11-15 year olds by leading games, showing the films, and facilitating discussion. The series is freely available on Sanctuary's website; individuals can access the material by creating an account, logging in, and downloading the course content. This RCT is to evaluate the effectiveness of the Youth Series course on improving youth's mental health literacy, knowledge, and attitudes towards help-seeking.",[141,62,26],[141,291],"Youth","2024-11-14",{"date":294,"type":39},"2024-11-18",{"date":294,"type":20},{"date":297,"type":20},"2025-05-31",{"name":299,"class":46},"Sanctuary Mental Health Ministries",{"id":301,"slug":302,"hasResults":11,"nctId":303,"briefTitle":304,"officialTitle":305,"acronym":306,"eligibilityCriteria":307,"healthyVolunteers":11,"sex":17,"minAge":308,"maxAge":309,"enrollmentInfo":310,"targetDuration":4,"studyType":21,"phases":312,"briefSummary":313,"conditions":314,"keywords":315,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":320,"lastUpdatePostDateStruct":321,"startDateStruct":323,"completionDateStruct":325,"leadSponsor":327,"locationsCount":252},"100552497","design-implementation-and-evaluation-of-an-intervention-within-video-game-for-mental-health-literacy-in-adolescents-and-young-adults-100552497","NCT06473857","Design, Implementation and Evaluation of an Intervention Within Video Game for Mental Health Literacy in Adolescents and Young Adults","Design, Implementation and Evaluation of an Intervention Within an Online Community Game for the Development of Mental Health Literacy in Adolescents and Young Adults","SCOTT","Inclusion Criteria:\n\n* French speaking Minecraft players (15 to 25 years old)\n\nExclusion Criteria:\n\n\\-","15 Years","25 Years",{"count":311,"type":20},300,[23],"Context Adolescence and early adulthood are crucial periods for the development and maintenance of habits, behaviors and beliefs favorable to health and mental well-being. These can have significant lifelong health consequences and social costs. In this age group, the Internet and smartphones are predominant. Based on these two observations, the project proposes to use the Internet, and more specifically, an online game, as a vector for public health intervention. Health literacy is recognized as a key determinant of health. It refers to the motivation and skills of individuals to access, understand, evaluate and use information to make decisions about their health. Improving the level of literacy is a major public health challenge if the population is to be in a position to take better charge of its health, particularly its mental health.\n\nObjective To evaluate the effect of a public health intervention on the development of mental health literacy in adolescents and young adults (15-25 years) delivered within an existing online community game.\n\nResearch hypothesis Developing and delivering a (multicomponent) public health intervention in an original setting, such as the game Minecraft, to a community of adolescents and young adults will improve their mental health literacy and thus enhance the primary, secondary and tertiary prevention of mental health disorders.\n\nMethods The project's overall methodology is based on a multidisciplinary approach. A pilot phase has already enabled us to develop the theoretical framework and constituent elements of an intervention, as well as its acceptability and feasibility.\n\nIntervention We will conduct a pragmatic cohort multiple randomised controlled trial over 24 months. The chosen methodology will enable us to implement an intervention with different components.\n\nThe intervention will involve: collective challenges of various kinds (component A) and exchanges with influencers of different profiles (component B). The control group will be offered access to conventional sources of health information and \"\"placebos\"\" of the components described above. The theme is mental health literacy, and the intervention delivered will equip the players (capacity-building, recognizing ill-being, warning signs, resources, etc.) to ultimately enable them to react better (empowerment) and thus promote young people's mental health.\n\nEvaluation The evaluation will follow the Medical Research Council's recommendations for the evaluation of complex interventions. It will consist of a process evaluation and an evaluation of effectiveness, all of which will be based on the use of mixed methods (observations of players receiving the intervention, analysis of chat exchanges made by players during the intervention, evaluation questionnaires and a standardized grid for collecting process indicators). The primary endpoint for the effect analysis is the mental health literacy score (global score) measured by the MHLq including four dimensions: (1) knowledge of mental health problems; (2) mistaken beliefs\u002Fstereotypes; (3) help-seeking and first-aid skills; and (4) self-help strategies.\n\nPerspectives The results of this research project will make it possible to 1) develop new relevant interventions on various health topics, using the results obtained for the different interventions carried out within Minecraft 2) Contribute to the evidence base on the effectiveness of Internet-based interventions.",[26],[316,317,318,319],"mental health","literacy","adolescent and young adults","video games","2024-06-19",{"date":322,"type":39},"2024-06-25",{"date":324,"type":20},"2024-06-30",{"date":326,"type":20},"2025-12-01",{"name":328,"class":46},"Assistance Publique - Hôpitaux de Paris"]