[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"mental-health-symptoms\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:mental-health-symptoms":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":5},"100571800","trans-stair-implementing-an-evidence-based-trauma-treatment-with-community-led-prep-navigation-100571800",false,"NCT06724965","Trans STAIR: Implementing an Evidence Based Trauma Treatment With Community Led PrEP Navigation","Trans STAIR: Implementing an Evidence Based Trauma Treatment With Community Led PrEP Navigation for Transgender and Nonbinary Persons Affected by Violence","Inclusion Criteria:\n\n* identify as transgender or nonbinary (non-cisgender)\n* be age 18 or older\n* confirmed HIV-negative status\n* eligible for PrEP based on CDC guidelines\n* indication of clinically significant PTSD or depressive symptoms\n* ability to speak and read in English and\u002For Spanish\n\nExclusion Criteria:\n\n* under 18 years old\n* cognitively impaired to the extent that it limits ability to consent\n* currently in a relationship or home where violence is occurring","ALL","18 Years",{"count":19,"type":20},90,"ESTIMATED","INTERVENTIONAL",[23],"NA","This pilot trial will leverage \"PrEP Well,\" an ongoing multi-level implementation strategy for providing PrEP in transgender\u002Fgender diverse (TGD)-serving contexts by integrating peer-led PrEP navigation with programming that addresses other social and structural needs of the TGD community (e.g., housing, legal, employment, gender-affirmation, primary care). PrEP Well has been implemented at the Trans Wellness Center (TWC) in LA since 2021. TWC is a first-of-its-kind community-led, trans-affirming, TGD community center made up of 5 community-based TGD service organizations that serve the local racially and ethnically diverse TGD community. Together with our community and implementation partners this NIMH-funded R34 will adapt evidence-based Skills Training in Affect and Interpersonal Regulation (STAIR) into a trans-affirming, culturally appropriate trauma treatment for TGD persons affected by HIV and violence (Trans STAIR); evaluate the acceptability, appropriateness, and feasibility of the Trans STAIR intervention (Phase 1 beta test; Aim 1); and conduct a Type 1: Hybrid Effectiveness-Implementation pilot randomized controlled trail (Phase 2 pilot RCT; Aims 2 and 3) of PrEP Well + Trans STAIR vs. PrEP Well alone to provide preliminary support for a fully powered larger multisite R01 to test the efficacy of PrEP Well + Trans STAIR.",[26,27,28],"PrEP Uptake Experiences","PrEP Adherence Experiences","Mental Health Symptoms",[30,31,32,33,34,35,36,37,38],"PrEP","HIV prevention","Trauma","Mental Health","PrEP adherence","PrEP uptake","STAIR","Skills Training in Affect and Interpersonal Regulation","Trauma Treatment","NOT_YET_RECRUITING","2026-05-29",{"date":42,"type":43},"2026-06-01","ACTUAL",{"date":45,"type":20},"2026-09",{"date":47,"type":20},"2026-12",{"name":49,"class":50},"San Diego State University","OTHER"]