[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"mental-health\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:mental-health":27},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,165,0,25,[9,48,79,90,115,145,176,212,237,264,299,335,366,392,434,458,482,503,530,559,590,622,651,679,698],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100053215","a-natural-history-of-cardiometabolic-disease-among-us-bhutanese-developing-the-cross-sectional-bhutanese-community-of-central-ohio-health-study-to-understand-acculturation-as-synergizing-socioenvironmental-and-biobehavioral-risk-factors-propagating--100053215",false,"NCT06991751","A Natural History of Cardiometabolic Disease Among US Bhutanese: Developing the Cross-Sectional Bhutanese Community of Central Ohio Health Study to Understand Acculturation as Synergizing Socioenvironmental and Biobehavioral Risk Factors Propagating ...","A Natural History of Cardiometabolic Disease Among US Bhutanese: Developing the Bhutanese Community of Central Ohio Health Study to Identify Synergizing Socioenvironmental and Biobehavioral Risk Factors Propagating Health Disparities From a Cross-Sectional Study","* INCLUSION CRITERIA:\n\nTo participate in this study all of the following criteria must be met:\n\n* Adults (aged 18 years and older) living in the United States\n* Identify as Bhutanese, which will be defined as those individuals that resided or had\u002Fhave their closest relatives residing in the Kingdom of Bhutan\n* Bhutanese identity will also include those that self-identify as Bhutanese-Nepali or Bhutanese American\n\nEXCLUSION CRITERIA:\n\nAn individual who meets any of the following criteria will be excluded from participation in this study:\n\n* Any South Asian participants that do not identify as Bhutanese.\n* Pregnant at time of study or screening","ALL","18 Years","100 Years",{"count":21,"type":22},50,"ESTIMATED","OBSERVATIONAL","Background:\n\nAs of 2021, almost 45 million people in the United States were foreign-born immigrants. South Asians, including people from Bhutan, are the fastest-growing immigrant subgroup in the US. Their income and education levels are higher than the US average. Yet they have worse physical and mental health outcomes than their White US-born counterparts. These risks include type 2 diabetes and obesity.\n\nObjective:\n\nThis natural history study will explore how life experiences and environmental factors affect heart health and metabolism among Bhutanese people living in the US.\n\nEligibility:\n\nAdults aged 18 years or older who identify as Bhutanese and live in the US.\n\nDesign:\n\nParticipants will be recruited and screened by the Bhutanese Community of Central Ohio (BCCO). They will have 1 visit to the BCCO s Arogya Clinic in Reynoldsburg. The visit will last 2 hours.\n\nParticipants will take a survey; they may use either English or Nepali. They will answer questions about their background; their experiences living in the US; and how their customs and habits might have changed. They will also be asked about their experiences with discrimination; their mental health and well-being; their community; quality of life; and overall physical health. The survey will take 60 minutes.\n\nParticipants will also speak with a researcher. They will be asked how they feel about providing biological samples; these may include saliva, blood, and urine. Their answers will be audio recorded.",[26,27],"Cardiometabolic Risk Factors","Mental Health",[29,30,31,32,33,34],"Bhutanese","South Asian","Community engaged","Biospecimen perceptions","Epidemiology","Syndemic","NOT_YET_RECRUITING","2026-07-10",{"date":38,"type":39},"2026-07-13","ACTUAL",{"date":41,"type":22},"2026-07-16",{"date":43,"type":22},"2026-08-31",{"name":45,"class":46},"National Institute of Environmental Health Sciences (NIEHS)","NIH",1,{"id":49,"slug":50,"hasResults":12,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":12,"sex":55,"minAge":18,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":58,"phases":59,"briefSummary":61,"conditions":62,"keywords":68,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":47},"100053892","early-phase-1-digital-intervention-delivered-via-street-medicine-to-increase-hiv-and-substance-use-care-among-survivors-of-sex-trafficking-100053892","NCT07699484","Digital Intervention Delivered Via Street Medicine to Increase HIV and Substance Use Care Among Survivors of Sex Trafficking","Digital Intervention Delivered Via Street Medicine to Increase HIV and Substance Use Care Among Survivors of Sexual Trafficking","1. Age 18 years and above at enrollment\n2. Woman\n3. Screen positive for lifetime sexual trafficking","FEMALE",{"count":57,"type":22},60,"INTERVENTIONAL",[60],"EARLY_PHASE1","The goal of this clinical trial is to learn if the CONNECT program helps women with a history of sex trafficking get connected to substance use, HIV\u002FSTI, and mental health services. It will also learn whether the program is practical to deliver and acceptable to participants. The main questions it aims to answer are:\n\nDoes CONNECT increase participants' engagement in substance use treatment (such as starting medication for opioid use disorder or therapy for alcohol use), HIV and STI prevention and treatment services (such as starting PrEP or getting tested for STIs), and mental health treatment (such as treatment for PTSD)? Is CONNECT feasible and acceptable for women with a history of sex trafficking?\n\nResearchers will compare CONNECT to usual care to see if CONNECT increases engagement in these health services. The program will be delivered in partnership with a Street Medicine team that provides care directly to unhoused women, with support from a trained care navigator.\n\nParticipants will:\n\nComplete the CONNECT program or receive usual care Work 1:1 with a care navigator who helps with referrals to substance use, HIV\u002FSTI, and mental health services (CONNECT group) Complete assessments at the start of the study and at a 2-month follow-up Answer questions about their substance use, health behaviors, mental health, and use of health services",[63,64,65,27,66,67],"Sex Trafficking","HIV","Substance Use (Drugs, Alcohol)","Sexual Violence","Treatment Engagement",[63,64,69,27,66,67],"Substance Use","2026-07-07",{"date":38,"type":39},{"date":73,"type":22},"2026-10-05",{"date":75,"type":22},"2028-06-30",{"name":77,"class":78},"Lifespan","OTHER",{"id":80,"slug":4,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":81,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":82,"keywords":83,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":87,"completionDateStruct":88,"leadSponsor":89,"locationsCount":47},"100592309",{"count":21,"type":22},[26,27],[29,30,31,32,33,34],"2026-07-01",{"date":86,"type":39},"2026-07-02",{"date":70,"type":22},{"date":43,"type":22},{"name":45,"class":46},{"id":91,"slug":92,"hasResults":12,"nctId":93,"briefTitle":94,"officialTitle":95,"acronym":4,"eligibilityCriteria":96,"healthyVolunteers":12,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":97,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":99,"conditions":100,"keywords":101,"overallStatus":106,"whyStopped":4,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":47},"100621241","mental-health-after-dexmedetomidine-for-electrical-storm-100621241","NCT07368062","Mental Health After Dexmedetomidine for Electrical Storm","Study Evaluating Dexmedetomidine in the Acute Treatment of Electrical Storm: Outpatient Follow-up of Mental Health INDices (SDATE OF MIND)","Inclusion Criteria:\n\n* Patients admitted to an intensive care unit with a diagnosis of electrical storm within the preceding 6 months\n* Previous participants in the SEDATE trial (NCT06281977)\n\nExclusion Criteria:\n\n\\- None",{"count":98,"type":22},70,"The goal of the research study is to measure mental health and quality of life indices of individuals treated for electrical storm (ES). The consequences of being admitted to an intensive care unit (ICU) with electrical storm as well as the treatments patients would have received, are currently not well understood. Understanding the mental health burden of these treatments among survivors can provide insights into how to improve care.\n\nThis is a study consisting of patients who participated in the SEDATE trial (dexmedetomidine vs usual standard of care to treat ES in the ICU). Patients who consent to participate in this study will be asked to complete a set of questionnaires 3-6 months after their ICU admission. The purpose of the questionnaires is to measure indices of mental health and health-related quality of life. Each questionnaire will take about 5-15 minutes to complete.\n\nIf patients have a scheduled follow-up at the University of Ottawa Heart Institute, a member of the research team will meet with them during their clinic visit to complete the questionnaires. Otherwise, they can be completed over the telephone.",[27],[102,103,104,105],"Electrical storm","Ventricular tachycardia","Dexmedetomidine","Mental health","RECRUITING","2026-06-30",{"date":84,"type":39},{"date":110,"type":39},"2025-03-15",{"date":112,"type":22},"2028-06",{"name":114,"class":78},"Ottawa Heart Institute Research Corporation",{"id":116,"slug":117,"hasResults":12,"nctId":118,"briefTitle":119,"officialTitle":119,"acronym":120,"eligibilityCriteria":121,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":122,"targetDuration":4,"studyType":58,"phases":124,"briefSummary":126,"conditions":127,"keywords":130,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":136,"lastUpdatePostDateStruct":137,"startDateStruct":138,"completionDateStruct":140,"leadSponsor":142,"locationsCount":144},"100635627","supporting-treatment-access-and-recovery-in-re-entry-star-r-100635627","NCT07555145","Supporting Treatment Access and Recovery in Re-entry (STAR-R)","STAR-R","Inclusion Criteria:\n\n* 18 years or older;\n* Proficient in reading and writing in the English language;\n* Are released from one of the participating jail\u002Fs; and\n* Have a current co-occurring substance use and mental health disorder, which includes both any substance use disorder (including alcohol) and mental health disorder (including depression, anxiety, trauma related disorders, bipolar, and\u002For schizophrenia) as documented by the participating jails.\n\nExclusion Criteria:\n\n* Are acutely suicidal based on the CSSRS; or\n* Are acutely psychotic (as this would require a higher level of care) based on SCID-5-RV.",{"count":123,"type":22},240,[125],"NA","This application is aimed at testing a multicomponent intervention called \"Maintaining Independence and Sobriety through Systems Integration, Outreach, and Networking-Criminal Justice (MISSION-CJ) or Peer Linkage Support post-release from two jails in Massachusetts for individuals with co-occurring substance use and mental health disorders (COD), given high rates of COD among incarcerated populations. The research will examine engagement in treatment, behavioral health outcomes, mediators and moderators, an economic analysis, and facilitators and barriers of MISSION-CJ implementation.",[27,128,129],"Substance Use Disorders","Co-occurring Mental and Substance Use Disorders",[131,132,133,134,135],"MISSION-CJ","co-occurring disorders","peer linkage support","mental health","substance use disorders","2026-06-29",{"date":84,"type":39},{"date":139,"type":22},"2026-08-01",{"date":141,"type":22},"2030-08-31",{"name":143,"class":78},"University of Massachusetts, Worcester",2,{"id":146,"slug":147,"hasResults":12,"nctId":148,"briefTitle":149,"officialTitle":150,"acronym":4,"eligibilityCriteria":151,"healthyVolunteers":152,"sex":17,"minAge":18,"maxAge":153,"enrollmentInfo":154,"targetDuration":4,"studyType":58,"phases":156,"briefSummary":157,"conditions":158,"keywords":161,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":167,"lastUpdatePostDateStruct":168,"startDateStruct":170,"completionDateStruct":172,"leadSponsor":174,"locationsCount":4},"100643902","development--validation-of-a-life-balance-program-for-parents-of-preschoolers-a-pilot-study-100643902","NCT07669896","Development & Validation of a Life Balance Program for Parents of Preschoolers: A Pilot Study","A Wonderful Life is Not a Dream-A Pilot Study on the Development and Effectiveness Validation of the Life Balance Improvement Program for Parents of Preschool Children","Inclusion Criteria:\n\n* Parents aged 18 to 65 years who have at least one preschool child aged 0 to 6 years\n* The primary caregiver of the child\n* Self-perceived poor life balance or high parenting stress\n* Self-perceived depressive or anxiety symptoms, with at least mild depression as indicated by the Beck Depression Inventory, or at least mild anxiety as indicated by the Beck Anxiety Inventory\n* Able to communicate in Mandarin Chinese and comply with the study procedures, including interviews and self-administered questionnaires\n\nExclusion Criteria:\n\n* The child has been diagnosed by a physician with a major physical illness, mental illness, or neurodevelopmental disorder\n* The parent has been diagnosed by a physician with a major physical or mental illness requiring long-term treatment",true,"65 Years",{"count":155,"type":22},30,[125],"This study aims to examine the relationships among life balance, parenting stress, and mental health in parents of preschool children, and to develop an individualized life balance promotion program for this population. Parents of preschool children will be recruited to support program development and to evaluate its feasibility and effectiveness.",[159,27,160],"Parenting Stress","Occupational Balance",[162,160,159,163,164,165,166],"Preschool Parents","Depression","Anxiety","Group Intervention","Individualized intervention","2026-06-21",{"date":169,"type":39},"2026-06-25",{"date":171,"type":22},"2026-07",{"date":173,"type":22},"2027-12",{"name":175,"class":78},"Chung Shan Medical University",{"id":177,"slug":178,"hasResults":12,"nctId":179,"briefTitle":180,"officialTitle":181,"acronym":182,"eligibilityCriteria":183,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":184,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":186,"conditions":187,"keywords":189,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":204,"lastUpdatePostDateStruct":205,"startDateStruct":206,"completionDateStruct":208,"leadSponsor":210,"locationsCount":47},"100643868","french-validation-of-the-recovery-assessment-scale-ras-fr-100643868","NCT07667686","French Validation of the Recovery Assessment Scale (RAS-FR)","Cross-Cultural Adaptation, French Validation, and Development of Derived Versions of the Recovery Assessment Scale (RAS) for the Assessment of Subjective Recovery in Mental Health","VAL-RAS-FR","Inclusion Criteria:\n\n* Adult patient (18 years or older)\n* Receiving psychiatric care at EPSM Metz-Jury (inpatient unit, day hospital, community mental health center \\[CMP\\], or intensive home-based psychiatric care service \\[EPSIAD\\]\u002Fpost-EPSIAD follow-up)\n* Able to understand French\n* Able to complete a self-report questionnaire independently or with assistance if needed\n* Patients under legal protection measures (guardianship or curatorship) may participate with the agreement of their legal representative, when applicable\n\nExclusion Criteria:\n\n* Major cognitive impairment\n* Severe clinical condition preventing questionnaire completion or understanding of French\n* Refusal to participate\n* Prisoner or person deprived of liberty by judicial or administrative decision",{"count":185,"type":22},260,"The VAL-RAS-FR study aims to cross-culturally adapt, validate, and develop derived versions of the Recovery Assessment Scale (RAS), an internationally used self-report measure of subjective recovery in mental health. The study will include 260 adult psychiatric patients receiving care at EPSM Metz-Jury in both inpatient and outpatient settings. Participants will complete the French version of the RAS (RAS-FR), the WHOQOL-BREF, and additional self-report questionnaires. A subgroup of participants will complete the RAS-FR again after one month to assess test-retest reliability. The study will also explore existential aspects of recovery through the development of the RAS-FR-EX (Existential Extension) and support the development of a shorter version, the RAS-FR-SF (Short Form), for clinical and research purposes.",[27,188],"Psychiatric Disorders",[190,191,192,193,194,134,195,196,197,198,199,200,201,202,203],"subjective recovery","psychiatric care","psychometric validation","Recovery Assessment Scale","patient-reported outcome","RAS","mental health recovery","quality of life","WHOQOL-BREF","cross-cultural adaptation","recovery-oriented care","existential recovery","RAS-FR","French validation","2026-06-19",{"date":169,"type":39},{"date":207,"type":22},"2026-06",{"date":209,"type":22},"2027-09",{"name":211,"class":78},"Etablissement Public de Santé Mentale de Metz-Jury",{"id":213,"slug":214,"hasResults":12,"nctId":215,"briefTitle":216,"officialTitle":216,"acronym":4,"eligibilityCriteria":217,"healthyVolunteers":152,"sex":55,"minAge":18,"maxAge":4,"enrollmentInfo":218,"targetDuration":4,"studyType":58,"phases":220,"briefSummary":222,"conditions":223,"keywords":4,"overallStatus":106,"whyStopped":4,"lastUpdateSubmitDate":204,"lastUpdatePostDateStruct":230,"startDateStruct":231,"completionDateStruct":233,"leadSponsor":235,"locationsCount":47},"100644016","phase-2-evaluating-the-effectiveness-of-the-common-elements-treatment-approach-ceta-in-peru-mechanisms-of-individual-and-intergenerational-change-100644016","NCT07667738","Evaluating the Effectiveness of the Common Elements Treatment Approach (CETA) in Peru: Mechanisms of Individual and Intergenerational Change","Inclusion Criteria:\n\n* live in San Juan de Lurigancho, Lima, Peru,\n* be at least 18 years of age,\n* have a child between the ages of 4 and 6, and\n* have the ability to travel to INFAM for study assessments and treatment sessions\n\nExclusion Criteria:\n\n* living outside of San Juan de Lurigancho,\n* those who are unable or unwilling to attend in-person sessions, or\n* the presence of severe intellectual disabilities or mental illness (these individuals will be referred to other local services)",{"count":219,"type":22},600,[221],"PHASE2","Recent advances in intervention research have revealed the promise of transdiagnostic, modular approaches implemented by lay paraprofessionals for the treatment of the most prevalent mental health concerns in settings affected by adversity (e.g., anxiety, depression, posttraumatic stress), but to date, few effectiveness trials have examined the indirect effects of treatment on intergenerational and economic outcomes or moderators of treatment effectiveness. There is thus a critical need not only for the continued expansion of the evidence-basis for care in low-resource settings, but also for the evaluation of factors contributing to effectiveness across multiple dimensions to gain a better understanding of the sustainability, long-term benefits, and cost-effectiveness of these approaches. The current study will conduct a rigorous evaluation of an existing program, the Common Elements Treatment Approach (CETA) with women (N=300) who are mothers of young children (ages 4-6). The trial will take place in the context of an integrated community care setting in Lima, Peru's most populous and impoverished district, San Juan de Lurigancho. The primary aims are to (1) evaluate the primary and indirect effects of CETA (2) examine moderators of treatment effectiveness, including implementation quality and neighborhood factors and (3) examine CETA's cost effectiveness. The central hypotheses are that (H1a) CETA will improve women's mental health, intimate partner violence, and parenting and that (H1b) CETA will have indirect benefits for women's economic outcomes and for their children's adjustment. It is also hypothesized (H2) that effectiveness will be enhanced by strong implementation quality and the presence of neighborhood promotive factors, and weakened by neighborhood disadvantage. Hypotheses will be evaluated using an RCT employing a longitudinal design with assessments at baseline (T1), post-test (T2), 6-month follow-up (T3) and 12-month follow-up (T4). Women will be randomized into the intervention condition (CETA + Enhanced Case Management \\[ECM\\]) or the comparison condition (ECM). Robust, multi-source (i.e., participant, therapist, supervisor, census data) and multi-method data (i.e., interview, observational assessment, google street view coding) will be gathered. The contribution will be significant by advancing research on both direct and long-term benefits of maternal mental health care for family systems, and is likely to provide important insights into the sustainability and cost effectiveness of these approaches. The expected outcome is an evidence-based, cost-effective, integrated approach to maternal mental health care that can be readily implemented by local organizations. Further, it is anticipated that learnings from this project will respond to broader global public health concerns and provide opportunity for cross-context reciprocal innovation. Expanding the evaluation of CETA delivered in Spanish not only has advantages for the specific context under study, but provides an important foundation for addressing health disparities in Spanish-language mental health services in the US as well.",[224,225,226,163,27,227,228,229],"Violence","Parenting","Poverty","Posttraumatic Stress","Economic Factors","Child Psychology",{"date":169,"type":39},{"date":232,"type":39},"2026-05-18",{"date":234,"type":22},"2030-04-30",{"name":236,"class":78},"University of Notre Dame",{"id":238,"slug":239,"hasResults":12,"nctId":240,"briefTitle":241,"officialTitle":242,"acronym":4,"eligibilityCriteria":243,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":244,"enrollmentInfo":245,"targetDuration":4,"studyType":58,"phases":247,"briefSummary":248,"conditions":249,"keywords":253,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":204,"lastUpdatePostDateStruct":258,"startDateStruct":259,"completionDateStruct":260,"leadSponsor":262,"locationsCount":47},"100643847","3d-reconstruction-vr-and-machine-learning-in-body-image-in-bariatrics-100643847","NCT07668492","3D Reconstruction, VR and Machine Learning in Body Image in Bariatrics","The Use of 3D Reconstruction, Virtual Reality, and Machine Learning in Addressing Body Image in Bariatric Metabolic Surgery.","Inclusion Criteria:\n\n* Tier 4 bariatric group\n* On waiting list for bariatric metabolic surgery\n* Able to stand unaided for at least 5 minutes\n\nExclusion Criteria:\n\n* Anyone who cannot provide informed consent\n* Anyone who is involved in current research or has recently been involved in any research prior to recruitment.","75 Years",{"count":246,"type":22},80,[125],"Studies have shown that following bariatric metabolic surgery (BMS), patients continue to experience dissatisfaction with their new body image and identity). The reason for this is poorly understood but negative body image perception after surgery is linked to poor psychological and clinical outcomes. Our pilot study looking at the acceptability and feasibility of 3D reconstruction and virtual reality (VR) in addressing body image in BMS found that participants felt better informed about how their body will change following significant weight loss and agreed this novel intervention would be beneficial in helping patients adjust to changes in their body after BMS.\n\nThe investigators propose a randomised control trial comparing group body image counselling and group body image counselling with 3D reconstruction and VR in addressing body image in BMS. The study aims to enrol 80 participants from the Tier 4 bariatric group at St Mary's Hospital and Chelsea \\& Westminster Hospital. After consent, participants will be divided into two groups: the control group will receive traditional group body image counselling, and the intervention group will receive the same counselling supplemented with VR and 3D reconstructed images depicting 15% and 25% total less body weight. Both groups will undergo four sessions over six months.\n\nThe investigators will collect data including body measurements and 3D images of the participant in their underwear using a secure password protected device at baseline and follow participants at 3, 6, 9, 12, 18, 24, and 36 months post-BMS. Patient reported outcomes will be assessed through patient-reported questionnaires.\n\nThis trial seeks to determine if integrating 3D reconstruction and VR technology into body image counselling can provide better support for patients adjusting to body image changes post-BMS, potentially leading to improved psychological and clinical outcomes.",[250,251,27,252],"Obesity (Disorder)","Body Image","Bariatric Surgery",[254,255,251,256,257],"3D Reconstruction","Virtual Reality","Machine Learning","Bariatric Metabolic Surgery",{"date":169,"type":39},{"date":207,"type":22},{"date":261,"type":22},"2030-03",{"name":263,"class":78},"Imperial College London",{"id":265,"slug":266,"hasResults":12,"nctId":267,"briefTitle":268,"officialTitle":269,"acronym":4,"eligibilityCriteria":270,"healthyVolunteers":152,"sex":17,"minAge":271,"maxAge":153,"enrollmentInfo":272,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":274,"conditions":275,"keywords":281,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":291,"lastUpdatePostDateStruct":292,"startDateStruct":294,"completionDateStruct":295,"leadSponsor":297,"locationsCount":47},"100644217","non-invasive-sleep-monitoring-for-burnout-and-retention-risk-in-postgraduate-nurses-100644217","NCT07666633","Non-Invasive Sleep Monitoring for Burnout and Retention Risk in Postgraduate Nurses","Development of a Non-Invasive Sleep-Based Prediction Platform for Burnout and Retention Risk Among Postgraduate Nurses: A Psychophysiological and AI-Driven Approach for High-Stress Clinical Populations","Inclusion Criteria:\n\n* Newly employed postgraduate nurses within the first 3 months of clinical practice\n* Age 20 to 65 years\n* Full-time clinical nursing staff\n* Able to read and complete Chinese questionnaires\n* Willing to participate in repeated psychological assessments and non-invasive sleep monitoring\n* Able to provide written informed consent\n\nExclusion Criteria:\n\n* Diagnosed severe sleep disorders\n* Diagnosed severe psychiatric disorders\n* Current use of medications that significantly affect sleep or autonomic nervous system function\n* Inability to comply with longitudinal follow-up procedures\n* Inability to complete repeated sleep monitoring assessments","20 Years",{"count":273,"type":22},100,"Newly graduated nurses often experience high levels of psychological stress, sleep disturbance, fatigue, and burnout during the early transition into clinical practice. Early identification of burnout and retention risk may help improve mental well-being, workforce stability, and quality of patient care.\n\nThis longitudinal observational study aims to develop a non-invasive sleep-based prediction platform for assessing burnout and retention risk among postgraduate nurses. Participants will undergo repeated psychological assessments and non-contact sleep monitoring during the study period. Sleep-related physiological parameters, including sleep efficiency, sleep structure, heart rate variability, and respiratory variability, will be collected together with validated psychological questionnaires.\n\nThe study will further apply machine learning and artificial intelligence approaches to integrate longitudinal physiological and psychological data for risk prediction and early identification of burnout-related conditions. The findings may support future development of precision mental health monitoring and supportive management strategies for high-stress healthcare workers.",[276,277,278,27,279,280],"Burnout","Sleep Disturbance","Occupational Stress","Nurse Retention","Fatigue",[282,283,284,285,286,256,287,288,289,290],"Postgraduate Nurses","Non-Invasive Sleep Monitoring","Burnout Risk","Retention Risk","Artificial Intelligence","Sleep Quality","Heart Rate Variability","Shift Work","Psychological Stress","2026-06-18",{"date":293,"type":39},"2026-06-24",{"date":139,"type":22},{"date":296,"type":22},"2027-04-23",{"name":298,"class":78},"Kaohsiung Armed Forces General Hospital",{"id":300,"slug":301,"hasResults":12,"nctId":302,"briefTitle":303,"officialTitle":304,"acronym":305,"eligibilityCriteria":306,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":307,"targetDuration":4,"studyType":58,"phases":309,"briefSummary":310,"conditions":311,"keywords":324,"overallStatus":106,"whyStopped":4,"lastUpdateSubmitDate":291,"lastUpdatePostDateStruct":327,"startDateStruct":329,"completionDateStruct":331,"leadSponsor":333,"locationsCount":47},"100638424","ecardiacrehab---a-hybrid-patient-centered-ehealth-programme-100638424","NCT07590635","eCardiacRehab - a Hybrid Patient-Centered eHealth Programme","eCardiacRehab - a Randomized Controlled Trial on a Hybrid Home-Based Patient-Centered eHealth Programme With Tailored Solutions","eCardiacRehab","Inclusion Criteria:\n\n* Adult Norwegian (or Scandinavian) speaking patients (≥ 18 years) who have a Norwegian national identification number\n* With coronary artery disease after percutaneous coronary intervention\n* Living at home\n* Have internet available\n* Provide signed informed consent\n\nExclusion Criteria:\n\n* Patients with cognitive impairment that may interfere with the ability to comply with the study protocol\n* Severe aortic stenosis\n* Severe arrhythmias\n* Expected lifetime less than one year as determined by study personnel\n* Otherwise clinically unstable\n* Not fully revascularized\n* Awaits percutaneous coronary intervention or coronary artery bypass graft surgery\n* Inability to comply with the study protocol due to any physical disability, somatic disease, or mental problems as determined by study personnel",{"count":308,"type":22},1000,[125],"The overall aim of eCardiacRehab trial is to meet rehabilitation needs of patients with coronary artery disease (CAD) regardless of their access to traditional place-based rehabilitation by developing and evaluating the efficacy and cost effectiveness of an interdisciplinary and comprehensive home-based hybrid programme. eCardiacRehab address patient- and system level challenges to increase access to cardiac rehabilitation (CR). We give particular attention to older patients, women, and those with comorbidities or mental health challenges. The vision of the hybrid home-based eCardiacRehab programme is to make CR available to all.\n\neCardiacRehab is a prospective, multicentre randomized open-label blinded end point evaluation (PROBE) trial. The primary endpoint is a hierarchical composite endpoint using a win-ratio framework combining cardiovascular (CV) death, unplanned contacts to the Emergency Department (ED) for observation or admission (\\>24 hours) for CV disease, and quality of life. Inclusion criteria are adult Scandinavian speaking patients (≥ 18 years) who have a Norwegian national identification number, with CAD treated with Percutaneous Coronary Intervention (PCI), are living at home, and have internet available to them and providing signed informed consent. Exclusion criteria are patients with severe aortic stenosis, severe arrhythmias, expected lifetime less than one year as determined by study personnel, otherwise clinically unstable, not fully revascularized, awaits PCI or coronary artery bypass graft operation (CABG) or inability to comply with the study protocol due to any physical disability, somatic disease, cognitive impairment or mental health challenges as determined by study personnel.",[312,313,314,315,316,317,318,319,320,27,321,322,323],"Comorbidities and Coexisting Conditions","Ethics","Continuity of Patient Care","Older Adults (65 Years and Older)","Cost-Benefit Analysis","Adherence, Medication","Secondary Prevention of Coronary Heart Disease","Health Literacy","eHealth Literacy","Cardiac Rehabilitation","Womens's Health","Coronary Artery Disease (CAD)",[321,325,326],"Coronary Artery Disease","Percutaneous Coronary Intervention",{"date":328,"type":39},"2026-06-23",{"date":330,"type":39},"2026-05-21",{"date":332,"type":22},"2037-12-31",{"name":334,"class":78},"Haukeland University Hospital",{"id":336,"slug":337,"hasResults":12,"nctId":338,"briefTitle":339,"officialTitle":340,"acronym":341,"eligibilityCriteria":342,"healthyVolunteers":152,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":343,"targetDuration":4,"studyType":58,"phases":344,"briefSummary":345,"conditions":346,"keywords":4,"overallStatus":106,"whyStopped":4,"lastUpdateSubmitDate":358,"lastUpdatePostDateStruct":359,"startDateStruct":360,"completionDateStruct":362,"leadSponsor":364,"locationsCount":47},"100544950","k-orca-testing-a-decision-support-tool-and-group-process-for-selecting-interventions-100544950","NCT06375551","K-ORCA: Testing a Decision Support Tool and Group Process for Selecting Interventions","Refining and Pilot Testing a Decision Support Intervention to Facilitate Adoption of Evidence-Based Programs to Improve Parent and Child Mental Health","K-ORCA","Inclusion Criteria:\n\n* Non-institutionalized\n* Adults (18 years or older).\n* English-Speaking\n\nAim 1:\n\n* Involved in initial state decision-making related to Family First Prevention Services Act.\n* Willing to participate in two data collection occasions.\n\nAim 2:\n\n* Non-institutionalized\n* Adults (18 years or older). English-Speaking.\n* Involved in ongoing state decision-making related to Family First Prevention Services Act.\n* Willing to participate in three measurement occasions.\n\nAim 3:\n\n-Willing to participate in multiple (bi-weekly up to two years) measurement occasions.\n\nExclusion Criteria:\n\n-Not involved in or potentially influencing child welfare intervention decisions",{"count":246,"type":22},[125],"This proposal responds to NIMH Objective 4.2.c to develop \"decision-support tools and technologies that increase the effectiveness and continuous improvement of mental health interventions\" by leveraging the Family First Prevention Services Act (FFPSA) policy opportunity. First, a web-based platform to host (a) a decision-support tool and (b) automated facilitation for group decisions with the tool will be developed with state partners' feedback. Next, decision makers leading their states' FFPSA quality improvement efforts will be engaged to pilot a decision-support intervention comprised of the tool and live or automated facilitation, and to evaluate the implementation quality of evidence-based programs adopted with the decision-support intervention.",[347,348,349,350,351,352,353,354,355,356,27,357],"Child Abuse","Decision Making","Child Welfare","Decision Making, Shared","Decision Support Technique","Social Facilitation","Implementation Science","Policy","Organizations","Consensus","Family","2026-06-16",{"date":291,"type":39},{"date":361,"type":22},"2026-12-01",{"date":363,"type":22},"2027-07-31",{"name":365,"class":78},"Chestnut Health Systems",{"id":367,"slug":368,"hasResults":12,"nctId":369,"briefTitle":370,"officialTitle":371,"acronym":4,"eligibilityCriteria":372,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":373,"targetDuration":4,"studyType":58,"phases":375,"briefSummary":376,"conditions":377,"keywords":379,"overallStatus":106,"whyStopped":4,"lastUpdateSubmitDate":383,"lastUpdatePostDateStruct":384,"startDateStruct":386,"completionDateStruct":388,"leadSponsor":390,"locationsCount":47},"100631879","hope-groups-parenting-and-mental-health-among-refugees-in-the-middle-east-100631879","NCT07506421","Hope Groups: Parenting and Mental Health Among Refugees in the Middle East","Hope Groups: A Small-Scale Randomised Controlled Trial Of Psychosocial And Parenting Support Groups For Palestinian Caregivers Affected By War In The Middle East","Inclusion Criteria:\n\n* Participant is living in one of our partner refugee camps.\n* Participant is a parent\u002Fcaregiver for one or more child (of any age).\n* Participant is over the age of 18.\n* Participant has high, medium, or low literacy. (Note: This is in order to use our Hope Groups programme guide. Our team is concerned that individuals with no literacy would need more audio files, rather than just a text-driven participant guide. If Hope Groups demonstrate effectiveness in this pilot, investigators will have focus groups with low-literacy participants, to create a future version which is suitable for people of all literacy backgrounds.)\n* Participant consents to participate in the study.",{"count":374,"type":22},490,[125],"This research is testing if 'Hope Groups' -- a psychosocial, mental health, parenting strengthening, and violence prevention support group program -- work to help Palestinian caregivers displaced by war.",[27,378],"Violence Against Children",[380,381,225,378,382],"War","Displacement","Refugee","2026-06-15",{"date":385,"type":39},"2026-06-17",{"date":387,"type":39},"2025-02-05",{"date":389,"type":22},"2026-11-01",{"name":391,"class":78},"University of Oxford",{"id":393,"slug":394,"hasResults":12,"nctId":395,"briefTitle":396,"officialTitle":397,"acronym":4,"eligibilityCriteria":398,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":399,"targetDuration":4,"studyType":58,"phases":401,"briefSummary":402,"conditions":403,"keywords":413,"overallStatus":106,"whyStopped":4,"lastUpdateSubmitDate":425,"lastUpdatePostDateStruct":426,"startDateStruct":427,"completionDateStruct":429,"leadSponsor":431,"locationsCount":433},"100509219","improving-alcohol-and-substance-use-care-access-outcome-equity-during-the-reproductive-years-100509219","NCT05910580","Improving Alcohol and Substance Use Care Access, Outcome, Equity During the Reproductive Years","Improving Alcohol and Substance Use Care Access, Outcomes, and Equity During the Reproductive Years: A Type 1 Hybrid Trial in Family Planning Clinics","Inclusion Criteria:\n\n* Over the age of 18 years\n* U.S. residing\n* Have internet access (own a computer or smart phone)\n* Screen positive to one or more risky alcohol and substance use behaviors as determined by our standardized abbreviated instruments\n\nExclusion Criteria:\n\n* Not capable of communicating (reading, speaking, writing) in English or Spanish",{"count":400,"type":22},400,[125],"The goal of this clinical trial is to test the effectiveness of evidence-based Screening, Brief Intervention, and Referral to Treatment (SBIRT) among adult patients who screen positive to one or more risky alcohol or substance use behaviors while seeking care at a sexual and reproductive health (SRH) clinic.\n\nThe main questions it aims to answer are:\n\n* Does SBIRT impact patients' alcohol and substance use, SRH, mental health, physical health, quality of life, and wellbeing?\n* Does SBIRT effectiveness differ by ethnicity, socioeconomic status, age, gender, and urbanicity?\n* Does SBIRT effectiveness differ by delivery mode (in-person vs. telemedicine)?\n\nParticipants will receive in-person and telemedicine SBIRT, or usual care. Participants will complete surveys at interviews at baseline, 30 days, and 3 months.\n\nResearchers will compare patients who received SBIRT to patients who receive usual care to see if patients who receive the SBIRT intervention have a greater reduction in negative outcomes as compared to those who receive usual care. In this setting, usual care consists of basic quantity and frequency questions asked inconsistently as part of the admission process and varying by provider, with no standardized approach to screening, treatment, follow-up, or referral.",[404,405,27,406,407,408,409,410,411,412],"Alcohol-Related Disorders","Substance-Related Disorders","Reproductive Health","Sexual Health","Sexually Transmitted Diseases","Contraception","Maternal Health","Pregnancy","Women's Health",[353,414,415,416,417,418,419,420,421,422,423,424],"Mass Screening","Motivational Interviewing","Referral and Consultation","Quality of Health Care","Early Medical Intervention","Family Planning Services","Primary Health Care","Reproductive Health Services","Telemedicine","Preconception Care","Young Adult","2026-06-12",{"date":383,"type":39},{"date":428,"type":39},"2025-07-03",{"date":430,"type":22},"2027-05-31",{"name":432,"class":78},"Emory University",4,{"id":435,"slug":436,"hasResults":12,"nctId":437,"briefTitle":438,"officialTitle":439,"acronym":4,"eligibilityCriteria":440,"healthyVolunteers":152,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":441,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":442,"conditions":443,"keywords":447,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":451,"lastUpdatePostDateStruct":452,"startDateStruct":453,"completionDateStruct":454,"leadSponsor":456,"locationsCount":4},"100643029","gansu-nurses-health-cohort-study-100643029","NCT07645911","Gansu Nurses' Health Cohort Study","Gansu Nurses' Health Surveillance and Improvement Action Program","Inclusion Criteria:\n\n1. Age ≥ 18 years;\n2. Able to communicate freely, have the ability to act, and agree to participate in this study.\n\nExclusion Criteria:\n\n1. Resigned from the hospital;\n2. Without a nursing license;\n3. Have a history of mental illness or severe cognitive impairment.",{"count":308,"type":22},"This study aims to understand the health status, work stress, and occupational exposure in the work environment among nurses in Gansu Province, China. We will collect information through questionnaires and conduct follow-up surveys every two years. The results of this study will help improve working conditions for nurses in the future and provide scientific evidence for developing health protection policies for the nursing workforce.",[444,27,445,446,406],"Nurses' Occupational Health","Chronic Diseases","Occupational Exposure",[448,449,450],"Nurses, Occupational Health, Questionnaire Survey","Nurse health status","Nurse Health Cohort Study","2026-06-10",{"date":425,"type":39},{"date":451,"type":22},{"date":455,"type":22},"2032-12-31",{"name":457,"class":78},"LanZhou University",{"id":459,"slug":460,"hasResults":12,"nctId":461,"briefTitle":462,"officialTitle":463,"acronym":4,"eligibilityCriteria":464,"healthyVolunteers":152,"sex":55,"minAge":465,"maxAge":466,"enrollmentInfo":467,"targetDuration":4,"studyType":58,"phases":469,"briefSummary":470,"conditions":471,"keywords":4,"overallStatus":106,"whyStopped":4,"lastUpdateSubmitDate":474,"lastUpdatePostDateStruct":475,"startDateStruct":476,"completionDateStruct":478,"leadSponsor":480,"locationsCount":47},"100642054","health-benefits-of-dance-exercise-100642054","NCT07615829","Health Benefits of Dance Exercise","Effects of a 6-month Dance Exercise Intervention on Physical Performance, Metabolic and Mental Health in Pre- and Post-menopausal Women","Inclusion Criteria:\n\n* Free of musculoskeletal injuries\n* Free of chronic non-communicable diseases\n* Normal menstrual cycle (for premenopausal women)\n* No recent childbirth (previous 12 months) (for premenopausal women)\n* At least 12 months since the oncet of menopause (for postmenopausal women)\n* Non smokers\n\nExclusion Criteria:\n\n* Pregnancy (for premenopausal women)\n* Contraindications to exercise training\n* Illness or other medical condition\n* Use of medication","35 Years","70 Years",{"count":468,"type":22},40,[125],"In Greece, people of different age groups, including young children to older adults, participate in dance exercise training. Although it is well-known that regular participation in dancing is associated with benefits such as entertainment, socialization and increased physical activity, the long-term effects of dancing on metabolic and mental health as well as physical performance remain largely unknown. Therefore, the aim of this study is to investigate the effects of a 6-month dancing exercise intervention on metabolic and mental health and physical performance in premenopausal and postmenopausal women.",[472,27,473],"Metabolic Health","Physical Performance","2026-06-09",{"date":425,"type":39},{"date":477,"type":22},"2026-05-30",{"date":479,"type":22},"2026-12-20",{"name":481,"class":78},"University of Thessaly",{"id":483,"slug":484,"hasResults":12,"nctId":485,"briefTitle":486,"officialTitle":487,"acronym":488,"eligibilityCriteria":489,"healthyVolunteers":12,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":490,"targetDuration":4,"studyType":58,"phases":491,"briefSummary":492,"conditions":493,"keywords":494,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":474,"lastUpdatePostDateStruct":498,"startDateStruct":499,"completionDateStruct":500,"leadSponsor":501,"locationsCount":47},"100641738","mentalizing-imagery-therapy-for-caregivers-to-address-risk-of-elder-mistreatment-100641738","NCT07648238","Mentalizing Imagery Therapy for Caregivers to Address Risk of Elder Mistreatment","Mentalizing Imagery Therapy for Caregivers to Address Risk of Elder Mistreatment (MIT-CARE)","(MIT-CARE)","Inclusion Criteria:\n\n* Primary family ADRD caregivers\n* Recruited nationally.\n* Caring for someone aged 60 or older\n* Provide at least 8 hours of care weekly\n* Report at least mild depressive symptoms (PHQ-9 ≥5)\n* Use a smartphone at least five days per week.\n\nExclusion Criteria:\n\n* Active psychosis or mania\n* A suicide attempt in the last 6 months or current suicidal intent\n* Self-reported memory or cognitive complaints\n* Unstable medical conditions or planned major surgery\n* Moderate to severe substance use disorders.",{"count":21,"type":22},[125],"The purpose of this study is to establish the clinical efficacy of Mentalizing Imagery Therapy (MIT) for Alzheimer's Disease and Related Disorders (ADRD) family caregivers in terms of mentalizing and elder mistreatment (EM) risk factors of stress, depression, and suicidality and to identify the mechanistic impacts of MIT on ADRD family caregivers' mental health,including stress, depression, and suicidality.",[27],[495,496,497],"Mentalizing Imagery Therapy","Mindfulness Exercises","dementia family caregiver",{"date":383,"type":39},{"date":139,"type":22},{"date":75,"type":22},{"name":502,"class":78},"The University of Texas Health Science Center, Houston",{"id":504,"slug":505,"hasResults":12,"nctId":506,"briefTitle":507,"officialTitle":507,"acronym":508,"eligibilityCriteria":509,"healthyVolunteers":152,"sex":17,"minAge":18,"maxAge":510,"enrollmentInfo":511,"targetDuration":4,"studyType":58,"phases":513,"briefSummary":514,"conditions":515,"keywords":518,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":474,"lastUpdatePostDateStruct":521,"startDateStruct":523,"completionDateStruct":525,"leadSponsor":527,"locationsCount":47},"100634401","precarity-and-reduction-of-its-impact-on-the-mental-health-of-health-students-100634401","NCT07539207","Precarity and Reduction of Its Impact on the Mental Health of Health Students","PRISMES","Inclusion Criteria:\n\n* Enrollment as a health student at the Faculty of Health, Université de Rouen Normandie (any program or discipline).\n\nAge between 18 and 30 years.\n\nMeet at least one of the following three financial vulnerability criteria:\n\nInsufficient monthly funds to cover basic living expenses. Recurrent monthly bank overdraft. Frequent omission of food purchases due to financial constraints. Affiliation with a social security scheme or beneficiary of such a scheme\n\nExclusion Criteria:\n\n* Participants meeting any of the following criteria will be excluded:\n\nCurrently receiving, or having received in the past 12 months, psychological or sophrology follow-up.\n\nCurrently treated for, or having been treated in the past 12 months for, anxiety or depression.","30 Years",{"count":512,"type":22},110,[125],"Student financial insecurity has become a major public health and societal issue affecting a growing proportion of young adults in higher education, exacerbated by the COVID-19 pandemic and more recently by inflation. Health students may be particularly exposed because of the demanding and lengthy nature of their training, often combined with limited opportunities for paid work due to hospital placements and academic workload. A national study conducted in 2024 by the Unit Institut national de la santé et de la recherche médicale U1073 under the supervision of the Conférence Nationale des Doyens de Médecine among more than 12,000 health students showed that 12% experienced severe financial insecurity, characterized by insufficient monthly resources, recurrent bank overdrafts, and frequent food deprivation, while 20% reported moderate insecurity. Financial insecurity was strongly associated with anxiety, depression, and emotional exhaustion, while vulnerable students were also more likely to forgo healthcare, including psychological consultations, for financial reasons. This vicious circle between financial hardship and mental health may compromise academic success and justifies targeted intervention.\n\nAlthough support systems such as Santé Psy Étudiant and free psychological consultations at the faculty already exist, they remain underused because of stigma, insufficient information, or perceived barriers to access. The PRISMES project proposes a participatory, adaptive, and real-world intervention designed to improve mental health support for financially vulnerable health students.\n\nStudents directly participate in the co-construction of interventions together with researchers, student associations, health professionals, academic representatives, and a sociologist involved in understanding social determinants, mental health representations, and barriers to participation. Three intervention formats will initially be proposed, Three types of interventions are offered to students. Intervention I consists of four individual psychological consultations. Intervention II includes two collective workshops focused on stress and budget management, combined with two sophrology sessions. Intervention III comprises one psychological consultation and two collective workshops on stress and budget management.. This non-randomized design reflects real-life implementation conditions and improves future transferability.\n\nThe main objective is to provide concrete support to financially vulnerable students by improving well-being, mental health, and knowledge of available support systems. Secondary objectives are to evaluate intervention effects on anxiety, depression, stress, quality of life, and emotional exhaustion, to adapt interventions according to feedback, and to improve awareness and use of social and health support services.\n\nA mixed-method design will combine quantitative and qualitative data. Quantitative assessments will be conducted monthly during the three months following the first intervention and again three months after the final intervention. Validated questionnaires will assess perceived stress (Cohen scale), anxiety and depression (HAD score), quality of life, and emotional exhaustion (MBI-SS). Qualitative interviews and focus groups conducted at the end of the intervention will explore perceived benefits, barriers, and implementation factors among students and professionals.\n\nThe adaptive design allows continuous adjustment according to interim findings. For example, if attendance is limited by timetable constraints, sessions may be rescheduled. Feedback loops involving participants and stakeholders will guide iterative improvement.\n\nEligible participants are health students aged 18-30 enrolled at Université de Rouen Normandie presenting at least one indicator of financial insecurity: insufficient monthly resources, recurrent overdraft, or frequent food deprivation. Students currently receiving psychological follow-up are excluded.\n\nAssuming a reduction in anxiety prevalence from 55% to 45%, 88 participants are required; with 20% loss to follow-up, 110 students will be included. Among approximately 4,500 health students in Rouen, about 540 are estimated to experience severe insecurity and 900 moderate insecurity, ensuring strong feasibility. PRISMES aims to generate directly transferable recommendations for university support policies and improve resilience, well-being, and academic success.",[516,27,517],"Mental Health (Depression)","Quality of Lifte",[519,520,134],"university student","economic precarity",{"date":522,"type":39},"2026-06-11",{"date":524,"type":22},"2026-09-15",{"date":526,"type":22},"2027-09-30",{"name":528,"class":529},"Institut National de la Santé Et de la Recherche Médicale, France","OTHER_GOV",{"id":531,"slug":532,"hasResults":12,"nctId":533,"briefTitle":534,"officialTitle":535,"acronym":4,"eligibilityCriteria":536,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":537,"targetDuration":4,"studyType":58,"phases":538,"briefSummary":539,"conditions":540,"keywords":545,"overallStatus":106,"whyStopped":4,"lastUpdateSubmitDate":551,"lastUpdatePostDateStruct":552,"startDateStruct":553,"completionDateStruct":555,"leadSponsor":557,"locationsCount":47},"100575899","transition-health-and-resilience-through-valued-experiences-thrive-pilot-for-newly-separated-veterans-100575899","NCT06778278","Transition Health and Resilience Through Valued Experiences (THRiVE) Pilot for Newly Separated Veterans","Adapting Behavioral Activation to Improve Mental Health Outcomes and Reduce Suicide Risk During the Military Transition","Inclusion Criteria:\n\n* Be either (a) a United States military veteran who separated no more than 12 months prior to study enrollment or (b) a United States transitioning service member on terminal leave\n* Be at least 18 years old\n* Have access to the internet; a desktop computer, laptop, tablet, or other \"smart\" device with video camera, speakers, and microphone; and a private place from which to attend THRiVE sessions\n* Reside and complete all study activities within the United States\n\nExclusion Criteria:\n\n* Endorse lifetime manic, hypomanic, or psychotic episodes\n* Meet Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria for current severe alcohol use disorder or substance use disorder (except for tobacco use disorder, which will not be exclusionary)\n* Screen positive for moderate or high acute risk for suicide\n* Screen positive for more than minimal risk for other-directed violence\n* Are receiving or plan to receive BA therapy for any mental health condition between enrollment and the 3-month follow-up assessment",{"count":468,"type":22},[125],"The objective of this study is to develop and pilot a program designed to improve mental health outcomes and reduce suicide risk during the transition from military to civilian life. It is hypothesized that the Transition Health and Resilience through Valued Experiences (THRiVE) program, to be developed as part of this study, will meet participant recruitment, retention, and satisfaction benchmarks (primary outcomes) and show positive preliminary effects on mental health symptoms, risk factors for suicidal ideation, and psychosocial functioning outcomes (secondary outcomes).\n\nThe specific aims of this study are to:\n\n1. Develop a small-group, peer-led, cross-cutting prevention program for newly separated veterans (NSVs) called THRiVE and\n2. Evaluate the feasibility, acceptability, and preliminary effects of the THRiVE program on mental health symptoms, risk factors for suicidal ideation, and psychosocial functioning outcomes.\n\nUp to 40 NSVs participating in this Stage 1 pilot study will complete validated self-report measures at baseline, immediately after completing the THRiVE program (post-THRiVE), and 3 months after completing the THRiVE program (follow-up). The duration of a participant's time in the study is anticipated to be 5 months.",[541,542,27,543,544],"Military Transition","Community Reintegration","Suicidal Ideation","Alcohol Misuse",[546,547,105,548,549,550],"Military transition","Community reintegration","Suicidal ideation","Transitioning Service Members","Newly separated Veterans","2026-06-08",{"date":451,"type":39},{"date":554,"type":39},"2025-07-30",{"date":556,"type":22},"2026-10-31",{"name":558,"class":78},"RTI International",{"id":560,"slug":561,"hasResults":12,"nctId":562,"briefTitle":563,"officialTitle":564,"acronym":565,"eligibilityCriteria":566,"healthyVolunteers":152,"sex":17,"minAge":567,"maxAge":18,"enrollmentInfo":568,"targetDuration":4,"studyType":58,"phases":570,"briefSummary":571,"conditions":572,"keywords":575,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":583,"lastUpdatePostDateStruct":584,"startDateStruct":585,"completionDateStruct":586,"leadSponsor":588,"locationsCount":47},"100642699","study-on-mental-health-promoting-effects-of-natural-psychotherapy-for-adolescents-100642699","NCT07639476","Study on Mental Health Promoting Effects of Natural Psychotherapy for Adolescents","The Effect of Universal Intervention Based on Natural Psychotherapy: Evidence From Chinese Adolescents","NP-A-MHP","Inclusion Criteria:\n\n* Ages: 7 to 18 years.\n* Population: School-aged children and adolescents currently enrolled and attending primary or secondary school.\n* Capacity: Ability to comprehend the study procedures and provide assent (or consent, if applicable).\n\nExclusion Criteria:\n\n* School Attendance: Children not currently attending school or on long-term academic leave.\n* General Exclusion: Any condition that, in the opinion of the investigator or school physician, would interfere with the participant's ability to attend school or comply with study procedures.","7 Years",{"count":569,"type":22},3000,[125],"This randomized controlled trial aims to evaluate the efficacy of a universal intervention based on Natural Psychotherapy in reducing anxiety and depressive symptoms among primary and middle school students. To evaluate both the clinical outcomes and the potential underlying mechanisms of change, data will be collected at four distinct time points: baseline (pre-intervention), post-intervention, 3-month follow-up, and 6-month follow-up.",[573,574,27],"Anxiety Disorders","Depressive Disorder",[576,163,577,578,579,580,581,582],"Mindfulness","Emotional Regulation","Cognitive Flexibility","Primary School Students","Middle School Students","Feasibility","Natural Psychotherapy","2026-06-06",{"date":451,"type":39},{"date":524,"type":22},{"date":587,"type":22},"2027-12-31",{"name":589,"class":78},"Beijing HuiLongGuan Hospital",{"id":591,"slug":592,"hasResults":12,"nctId":593,"briefTitle":594,"officialTitle":595,"acronym":4,"eligibilityCriteria":596,"healthyVolunteers":152,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":597,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":598,"conditions":599,"keywords":604,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":613,"lastUpdatePostDateStruct":614,"startDateStruct":616,"completionDateStruct":618,"leadSponsor":620,"locationsCount":4},"100637543","high-intensity-use-of-urgent-and-emergency-care-a-mixed-methods-study-100637543","NCT07630012","High Intensity Use of Urgent and Emergency Care: A Mixed-Methods Study","High Intensity Use of Urgent and Emergency Care: a Mixed-methods Study Exploring Needs, Experiences and Priorities to Co-produce a Preventative Intervention Model","Inclusion Criteria:\n\nAdults aged 18 or over who have been identified as experiencing high intensity use of urgent and emergency care services at University Hospitals Dorset, defined as five or more unplanned contacts within a 12-month period Adults aged 18 or over who provide unpaid care or support to someone who experiences high intensity use of urgent and emergency care services Health and social care professionals aged 18 or over involved in urgent and emergency care pathways at University Hospitals Dorset, Dorset HealthCare, Dorset Council or voluntary sector partner organisations Able to provide informed consent Willing to take part in an audio-recorded interview-\n\nExclusion Criteria:\n\nUnder 18 years of age Unable to provide informed consent Currently experiencing an acute mental health crisis requiring immediate clinical intervention Known history of violence or aggression towards health and social care professionals Currently receiving inpatient treatment at the time of recruitment No direct involvement in urgent and emergency care pathways at the participating organisations (professionals only)",{"count":246,"type":22},"This study aims to understand the health and social care needs and experiences of adults who frequently use urgent and emergency care services in Dorset. Using a mixed-methods design, the study combines analysis of non-patient-identifiable business intelligence data with qualitative interviews and co-production activities. The business intelligence data contextualises patterns of high intensity service use and informs participant identification. Qualitative interviews will explore the personal, social and system-level factors that contribute to frequent attendance. Co-production activities with an advisory group, supported by The Lantern Trust in Weymouth, will use these findings to develop a preventative intervention model grounded in lived experience. The study will recruit up to 50 patients, up to 10 carers and up to 20 health and social care professionals. The findings will contribute to the development of more effective, person-centred approaches to supporting people who frequently use urgent and emergency care services and will inform national and local policy in this area.",[600,601,602,27,603],"High Intensity Use of Urgent and Emergency Care","Emergency Medicine","Health Inequalities","Alcohol Use Disorder (AUD)",[605,606,607,608,609,610,611,612],"High intensity use","Frequent attenders","Urgent and emergency care","Mixed methods","Co-production","Qualitative research","Health and social care needs","Preventative intervention","2026-06-01",{"date":615,"type":39},"2026-06-05",{"date":617,"type":22},"2026-09-01",{"date":619,"type":22},"2029-04-01",{"name":621,"class":78},"Bournemouth University",{"id":623,"slug":624,"hasResults":12,"nctId":625,"briefTitle":626,"officialTitle":627,"acronym":628,"eligibilityCriteria":629,"healthyVolunteers":152,"sex":630,"minAge":18,"maxAge":4,"enrollmentInfo":631,"targetDuration":4,"studyType":58,"phases":633,"briefSummary":634,"conditions":635,"keywords":639,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":477,"lastUpdatePostDateStruct":644,"startDateStruct":646,"completionDateStruct":647,"leadSponsor":649,"locationsCount":4},"100639122","conscious-a-pilot-trial-of-a-media-orientation-intervention-to-encourage-mens-help-seeking-for-mental-health-difficulties-100639122","NCT07627451","CONSCIOUS: A Pilot Trial of a Media Orientation Intervention to Encourage Men's Help Seeking for Mental Health Difficulties","Media Orientation to Prevent Suicidal Ideation and Self Harm and Improve Help Seeking Behaviour: A Pilot Randomised Controlled Trial","CONSCIOUS","Inclusion Criteria:\n\n* male, aged 18 years or above, able to provide full informed consent to aid their participation, able to speak the English language which is Nigeria language. able to take part in the intervention and are available for the intervention assessment at baseline and end of intervention.\n\nExclusion Criteria:\n\n* less than 18 years old, unable to provide informed consent, undergoing severe mental health treatment and unable to speak the English language. Participants were also excluded if they are high risk social ideation or self-harm patients.","MALE",{"count":632,"type":22},74,[125],"Mental health difficulties among males are an issue of public health concern. Men are also at higher risk of suicidal ideation and self-harm and are poor at help-seeking due to factors including stigma, cultural norms and gendered expectations of masculinity. Yet, in Nigeria, a significant gap remains in media orientation intervention to create awareness on symptoms of mental health difficulties and support channels to encourage help-seeking. In essence, the current study aims to test the feasibility and acceptability of a novel intervention titled, psyChosOcial media awareNesS for SuiCIde symptoms, including other mental health PrOblems and help seeking mediUmS (CONSCIOUS) for addressing awareness of mental health difficulties in comparison to the waitlist control group for the purposes of improving men's help seeking, social support and reducing anxiety in Nigeria.",[164,27,636,637,638],"Suicide Awareness","Awareness Training","Public Health",[640,641,642,643],"Help-seeking for mental health difficulties","suicidal ideation","self harm awareness","media awareness for mental health difficulties",{"date":645,"type":39},"2026-06-04",{"date":107,"type":22},{"date":648,"type":22},"2027-06-03",{"name":650,"class":78},"Teesside University",{"id":652,"slug":653,"hasResults":12,"nctId":654,"briefTitle":655,"officialTitle":656,"acronym":4,"eligibilityCriteria":657,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":658,"targetDuration":4,"studyType":58,"phases":660,"briefSummary":661,"conditions":662,"keywords":667,"overallStatus":106,"whyStopped":4,"lastUpdateSubmitDate":671,"lastUpdatePostDateStruct":672,"startDateStruct":673,"completionDateStruct":675,"leadSponsor":677,"locationsCount":47},"100637411","cansolve-20-theme-31-mind-the-gap---dialectical-behavioural-therapy-dbt-skills-training-program-pilot-100637411","NCT07628309","CanSOLVE 2.0 Theme 3.1 Mind the Gap - Dialectical Behavioural Therapy (DBT) Skills Training Program Pilot","CanSOLVE 2.0 Theme 3.1 Mind the Gap: Addressing Mental Health Care Gaps for Canadians Receiving Facility-Based Hemodialysis - Dialectical Behavioural Therapy (DBT) Skills Training Program Pilot Intervention","Inclusion Criteria:\n\n* Age \\> 18 years old\n* Individuals followed in the Manitoba Kidney Health Program at Seven Oaks General Hospital or Health Sciences Centre sites with advanced chronic kidney disease not yet on facility-based hemodialysis but with plans to start within 1 month; OR\n* Individuals followed in the Manitoba Kidney Health Program at the SOGH or HSC sites who have initiated facility-based hemodialysis within the last 90 days\n* Able and willing to attend weekly DBT sessions (either virtually or in-person)\n* Experiencing self-reported psychological distress related to advanced kidney disease or initiation of hemodialysis\n* Deemed eligible to participate by study clinical psychologist\n\nExclusion Criteria:\n\n* Unable to complete intervention due to planned relocation\u002Ftransplant\u002Fmodality change\n* Unable to communicate in English\n* Deemed by hemodialysis unit staff\u002Fphysician\u002Fstudy psychologist to be unable to participate fully in study activities due to:\n\n  * Actively participating in psychiatric care with psychiatric (DSM-5) diagnosis\n  * Requiring referral for psychiatric care as per facility-based HD care provider assessment\n  * Current psychotic symptoms\n  * Cognitive impairment that would limit ability to participate in group or complete homework\n  * Safety risk to staff (e.g. physical aggression)\n  * Antisocial personality disorder or other issues that may limit ability to constructively participate in peer group\n  * Severe comorbid substance use disorder (if present will offer referral to addictions resources or Addictions Psychiatry)",{"count":659,"type":22},35,[125],"The goal of this pilot implementation study is to implement and evaluate a 13-week dialectical behavioural therapy (DBT) skills training program to address challenges to mental health and mental wellbeing in people who have recently started facility-based hemodialysis or those who may start within the next 6-12 months.",[27,663,664,665,666],"Mental Health Care","Hemodialysis","DIALYSIS SYMPTOMS AND ANXIETY","Health Related Quality of Life",[668,134,669,670],"hemodialysis","dialysis anxiety","mental well-being","2026-05-29",{"date":615,"type":39},{"date":674,"type":39},"2026-03-05",{"date":676,"type":22},"2026-07-15",{"name":678,"class":78},"University of Manitoba",{"id":680,"slug":681,"hasResults":12,"nctId":682,"briefTitle":683,"officialTitle":684,"acronym":4,"eligibilityCriteria":685,"healthyVolunteers":152,"sex":17,"minAge":18,"maxAge":153,"enrollmentInfo":686,"targetDuration":4,"studyType":58,"phases":688,"briefSummary":689,"conditions":690,"keywords":4,"overallStatus":106,"whyStopped":4,"lastUpdateSubmitDate":671,"lastUpdatePostDateStruct":691,"startDateStruct":692,"completionDateStruct":694,"leadSponsor":696,"locationsCount":144},"100628816","testing-multi-level-scale-up-strategies-ugandan-school-system-100628816","NCT07466563","Testing Multi-level Scale-Up Strategies: Ugandan School System","TESTING MULTI-LEVEL SCALE-UP STRATEGIES TO IMPLEMENT A SCHOOL-BASED POPULATION APPROACH OF MENTAL HEALTH PREVENTIVE INTERVENTION: UGANDA","Inclusion Criteria:\n\nTTCs and tutors:\n\n* 12 TTCs (out of a total 26 TTCs) will be selected.\n* All tutors will be aged 18-65, and currently employed under the educational system.\n* Tutors from each TTC will be recruited and trained in EBI implementation and management\n\nSchools:\n\n* 10 public schools (5 match pairs, match in size) under each TTC will be selected, and Principals of public schools will be invited to attend information sessions.\n* All principals will be aged 18-65, and currently employed under the educational system.\n\nPTTs and teachers:\n\n* All pre-primary teachers serving students between the ages of 3 and 12 years at the 120 study schools will be eligible to participate.\n* All teachers will be aged 18-65, and currently employed under the educational system.\n\nExclusion Criteria:\n\n* Inability to provide informed consent\n* Teachers who are not teaching students in the selected schools or not within the TTC service region.",{"count":687,"type":22},1556,[125],"The overall objective of the project is to address the school mental health evidence-based interventions (EBIs) scale-up and sustainability challenges in low-and-middle-income countries (LMICs) by studying \"system level intervention\" strategies. The project tests a scale-up model utilizing a two-level train-the-trainer model to support the expansion of an evidence-based intervention (mWEL -Teacher Professional Development; PD) in one LMIC (Uganda). mWEL-PD is the abbreviation of \"Promoting Mental Wellbeing \\& Empowering Lives of the School Community\". mWEL -PD is a teacher intervention that trains teachers to apply evidence-based strategies to engage parents and to promote student's mental health in classroom, as well as to promote teachers' own mental wellbeing. PD has been adapted and tested in Uganda and has demonstrated effectiveness in promoting Ugandan teachers' practices, teacher wellbeing, and students' mental health. Previous studies only applied one-level of the train-the-trainer model. This new study will test a new two-level of the train-the-trainer model that include a digital-learning system to scale PD, so that more teachers can be trained on PD, and more students can benefit from teachers' training and practice changes. Investigators will also test the new EBI\u002FPD scale-up model with and without including additional sustainability strategies (including technical assistance and continuing education strategies). Investigators will carry out an evaluation study (using a cluster-randomized trial design) to understand the impacts of the new two-level training model. The participants of the study will be the trainers and trainees, and the outcomes will be their implementation and practice outcomes.",[27],{"date":613,"type":39},{"date":693,"type":39},"2026-03-18",{"date":695,"type":22},"2029-03-31",{"name":697,"class":78},"NYU Langone Health",{"id":699,"slug":700,"hasResults":12,"nctId":701,"briefTitle":702,"officialTitle":702,"acronym":4,"eligibilityCriteria":703,"healthyVolunteers":152,"sex":630,"minAge":18,"maxAge":4,"enrollmentInfo":704,"targetDuration":4,"studyType":58,"phases":705,"briefSummary":706,"conditions":707,"keywords":709,"overallStatus":106,"whyStopped":4,"lastUpdateSubmitDate":714,"lastUpdatePostDateStruct":715,"startDateStruct":716,"completionDateStruct":718,"leadSponsor":719,"locationsCount":47},"100610341","testing-the-wecare-intervention-to-address-mental-health-and-medication-adherence-challenges-among-msm-in-south-africa-100610341","NCT07226323","Testing the WeCare Intervention to Address Mental Health and Medication Adherence Challenges Among MSM in South Africa","Inclusion Criteria:\n\n* Male\n* reports sexual intercourse with a man in the past 6 months\n* reside in the Johannesburg metropolitan area with no plans to relocate during the next 6 months\n* ability to communicate in English\n* current prescription for any ART regimen (HIV-positive participants) or daily oral PrEP (HIV-negative participants) at the POP INN clinic.\n* HIV positive participant only: unsuppressed HIV viral load (HIV-1 RNA viral load ≥200 copies\u002FmL) in the sample collected in the past six months\n* HIV negative participants only: Self-reported challenges adhering to daily oral PrEP (i.e miss 3 or more tablets per week)\n* Moderate symptoms of depression during past 2 weeks (score on the PHQ-9 ≥10 and \\\u003C20)\n* Ability to understand and provide informed consent.\n\nExclusion Criteria:\n\n* Presently engaged in mental health therapy.\n* Participated in qualitative phase of WeCare study (AUR2-18-419) or open-pilot (present study).\n* Refuses audio recording of the in-person or online individual counselling session",{"count":57,"type":22},[125],"The goal of this clinical trial is to learn if the WeCare intervention-an adapted Friendship Bench program that integrates problem-solving therapy, minority-stress-informed content, and explicit PrEP\u002FART adherence skills-improves mental health and HIV medication adherence among men who have sex with men (MSM). It will also assess the safety, acceptability, and feasibility of delivering WeCare through trained lay coaches in community clinics.\n\nMain questions the trial aims to answer:\n\n* Does WeCare reduce symptoms of depression and anxiety among MSM?\n* Does WeCare improve PrEP and ART adherence and increase rates of viral suppression among participants on ART?\n* Is WeCare acceptable, feasible, and safe when delivered by lay coaches in POP INN clinics compared with usual care?",[708,27],"HIV Infections",[710,711,712,713],"Men having sex with Men","Medication adherence","PrEP Adherence","ART Adherence","2026-05-27",{"date":671,"type":39},{"date":717,"type":39},"2025-12-01",{"date":363,"type":22},{"name":432,"class":78}]