[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"metabolic-disturbance\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:metabolic-disturbance":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,47,73,96,132,154,182],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":32,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100509938","improved-muscle-metabolism-by-combination-of-muscle-activation-and-protein-substitution--imempro--100509938",false,"NCT05919940","Improved Muscle Metabolism by Combination of Muscle Activation and Protein Substitution ( IMEMPRO )","Improved Muscle Metabolism by Combination of Muscle Activation and Protein Substitution: a Randomized, Outcome-assessor Blinded, Proof-of-concept Study (IMEMPRO)","Inclusion Criteria:\n\n* critically ill adults (≥ 18 years of age)\n* newly admitted to the ICU (\\\u003C48h)\n* mechanically ventilated, expected to remain for at least 72h\n* enteral nutrition is feasible\n\nExclusion Criteria:\n\n* a BMI \\> 30\n* expected death or withdrawal of life-sustaining treatments\n* prior neuromuscular disease (e.g. paresis, myopathies, neuropathies)\n* injury or disease preventing neuromuscular electrical stimulation or early mobilization (e.g., elevated intracranial pressure, unstable spine)\n* a pacemaker or other electronic implant\n* allergy to components of NMES adhesive\n* have been dependent during activities of daily living prior to the hospital admission\n* a language barrier","ALL","18 Years",{"count":19,"type":20},40,"ESTIMATED","INTERVENTIONAL",[23],"NA","Intensive Care Unit Acquired Weakness (ICUAW) describes muscle weakness that occurs in around 40% of patients during an intensive care stay. The morbidity and mortality of these patients is significantly increased over a 5-year period. The aim of this study is to investigate the combined effect of early enteral high-protein nutrition and early muscle activation on muscle atrophy in critically ill patients.\n\nThe study will include 40 patients (20 intervention, 20 observation) with requirement for enteral nutrition at time of inclusion. In the intervention group the maximum possible level of mobilization is carried out and muscles are activated twice a day using neuromuscular electrical stimulation (NMES). The nutrition plan of the intervention group is based on the applicable guidelines for intensive care medicine with exception of increased protein intake. The control group receives therapy without deviating from the standard according of the DGEM guideline.\n\nThe study aims to show that the decrease in muscle mass is significantly less than in the control group (primary hypothesis) via ultrasound of the rectus femoris muscle and in case of given consent muscle biopsy. As secondary hypothesis it is examined whether the combination of early high protein intake and muscle activation improves muscle strength and endurance.",[26,27,28,29,30,31],"ICU Acquired Weakness","Muscle Atrophy","Energy Malnutrition Protein","Quality of Life","Morphological and Microscopic Findings","Metabolic Disturbance",[33],"Early Mobilization and high-protein nutrition","RECRUITING","2026-02-28",{"date":37,"type":38},"2026-03-03","ACTUAL",{"date":40,"type":38},"2023-06-27",{"date":42,"type":20},"2027-01-31",{"name":44,"class":45},"Technical University of Munich","OTHER",4,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":55,"minAge":4,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":21,"phases":58,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":72},"100551036","multiple-risk-factor-intervention-trial-in-breast-cancer-survivors-100551036","NCT06454864","Multiple Risk Factor Intervention Trial in Breast Cancer Survivors","Multiple Risk Factor Intervention Trial In Breast Cancer Survivors","MsFITBC","Inclusion Criteria:\n\n* Biologically female\n* Diagnosis of stage I, II, or III breast cancer, post-menopausal at the time of diagnosis (haven't had a menstrual cycle within 12 months or greater)\n* Receipt of aromatase inhibitors for 12 months or more in the past, but do not have to be currently on aromatase inhibitors.\n* Willing and able to complete all study assessments\n* BMI ≥ 25 kg\u002Fm2\n* Able to commit to come to the University once per week for 24 weeks.\n\nExclusion Criteria:\n\n* Received chemotherapy within the past 11 months\n* Diagnosed with metastatic cancer\n* Currently taking tamoxifen\n* Currently receiving chemotherapy, targeted therapy or radiation treatment\n* Distant recurrence or diagnosis of metastatic cancer since early-stage breast cancer diagnosis\n* Diagnosed cardiovascular diseases, type 2 diabetes, non-alcoholic fatty liver disease, uncontrolled thyroid condition, or respiratory disease (e.g., COPD or severe or uncontrolled asthma).\n* Major signs or symptoms of cardiovascular diseases, diabetes, or renal disease (taken from the American College of Sports Medicine's Guidelines for Exercise Testing and Prescription 11th edition Table 2.1: pain or discomfort in the chest, neck, jaw, arms with rest or exercise, shortness of breath at rest or with mild exertion, dizziness or syncope, loss of balance or passing out, ankle edema, palpitations or tachycardia, intermittent claudication, known heart murmur, unusual fatigue with usual activities.)\n* American Heart Association's absolute or relative contraindications for symptom-limited maximal exercise testing (myocardial infarction, aortic or coronary artery stenosis, heart failure, pulmonary embolism or deep vein thrombosis, inflammation of the heart (myocarditis, pericarditis, and\u002For endocarditis), uncontrolled cardiac arrhythmia, advanced or complete electrical heart block, stroke or transient ischemia attack, blood pressure \\>200mmHg\u002F100mmHg, a cancer diagnosis other than skin cancer)\n* Unable to provide informed consent or communicate in English\n* Pregnant or breast-feeding currently or in the past 3 months\n* Mobility limitations to aerobic exercise (i.e., wheelchair, walker use, limp impeding walking)\n* Smoking cigarettes or marijuana within the past 3 months\n* Taking exogenous hormones in any format currently or in the past 3 months\n* Contraindications to research MRI (e.g., pacemaker, magnetic implants)\n* BMI exceeding 40 kg\u002Fm2\n* Extreme claustrophobia\n* Self-report \\>30 min\u002Fweek of moderate-to-vigorous intensity aerobic physical activity\n* Following a diet that largely restricts entire food groups or time of eating (e.g., vegan, ketogenic, carnivore, one meal a day) in last 3 months\n* Experienced significant weight loss (i.e., \\>5 kg) in past 3 months\n* Currently taking weight loss medications\n* Diagnosed history of an eating disorder or self-report of potential undiagnosed eating disorder\n* Plans to be away\u002Funavailable for a substantial period of the intervention overall (i.e., \\>4 weeks throughout the 6 months or \\>2 weeks within the first 12 weeks of the intervention).\n* Allergies to local anesthetics","FEMALE",{"count":57,"type":20},45,[23],"This study aims to produce new evidence on the efficacy of exercise and diet for cardiometabolic risk reduction in BC survivors. Using a 3-arm RCT with to 6 months of 1) exercise following Health Canada guidelines; 2) the same exercise plus counselling to follow Canada's Dietary Guidelines to improve diet quality; or 3) stretching group, this study will answer the following questions:\n\n* What is the impact of exercise on cardiometabolic health and body composition in BC survivors?\n* What is the effect modification of adding a diet quality intervention to exercise on cardiometabolic health and body composition?\n* Is there a link between the capacity of skeletal muscle adaptation to exercise (and diet) and insulin resistance in BC survivors?\n\nThe investigators hypothesize that: 1) exercise will improve cardiometabolic and body composition outcomes 2) improvements in cardiometabolic outcomes will be enhanced by the addition of diet quality, which will be essential or additive for Matsuda index, metabolic syndrome, Framingham CVD risk, thigh myosteatosis, muscle mass, VO2peak, 3) skeletal muscle insulin signalling transduction will be impaired in BC survivors via dampened expression of insulin-responsive proteins (e.g. GLUT4) and co-occur with impaired muscle quality (e.g., higher rates of fat depots, presence of fibrous tissue) negatively impacting insulin signalling.",[31,61,62],"Sedentary Behavior","Breast Cancer Female","2025-09-26",{"date":65,"type":38},"2025-10-01",{"date":67,"type":38},"2024-07-01",{"date":69,"type":20},"2027-04-01",{"name":71,"class":45},"University of Toronto",1,{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":55,"minAge":80,"maxAge":4,"enrollmentInfo":81,"targetDuration":4,"studyType":21,"phases":83,"briefSummary":84,"conditions":85,"keywords":86,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":72},"100542674","multiple-risk-factor-intervention-trial-ms-fit-100542674","NCT06345937","Multiple Risk Factor Intervention Trial (Ms. FIT)","MsFIT","Inclusion Criteria:\n\n* Biologically female\n* Aged 30+\n* Pre- or postmenopausal: Premenopause: having regular menstrual cycles (21-35 days long without a persistent difference of ≥7 days between cycles). Post-menopause: ≥12 months of amenorrhea or history of double oophorectomy and do not have irregular or occasional menstrual cycle in last 12 months.\n* Participants will have multiple risk factors for cardiometabolic disease, namely: being sedentary (\\\u003C30 min of moderate-vigorous physical activity\u002Fweek), having a BMI ≥ 25 kg\u002Fm\\^2, and one or more of the following: a waist circumference indicative of abdominal obesity, specific to BMI (e.g., BMI 25-29.9: WC: ≥90cm; BMI 30-34.9: WC: ≥105cm; BMI 35-35.9: WC: ≥115cm) OR a diagnosis of either hypertension, pre-diabetes (heightened blood sugar levels), or dyslipidemia (heightened blood lipid levels)\n* Able to commit to come to the University once per week for 24 weeks.\n\nExclusion Criteria:\n\n* Perimenopausal or those whom the investigators cannot discern pre- vs perimenopausal status\n* Diagnosed cardiovascular diseases, type 2 diabetes, non-alcoholic fatty liver disease, cancer (except for non-melanoma skin cancer), or respiratory disease (e.g., Chronic obstructive pulmonary disease (COPD) or severe or uncontrolled asthma).\n* Major signs or symptoms of cardiovascular diseases, diabetes, or renal disease (taken from the American College of Sports Medicine's Guidelines for Exercise Testing and Prescription 11th edition Table 2.1: pain or discomfort in the chest, neck, jaw, arms with rest or exercise, shortness of breath at rest or with mild exertion, dizziness or syncope, loss of balance or passing out, ankle edema, palpitations or tachycardia, intermittent claudication, known heart murmur, unusual fatigue with usual activities.)\n* American Heart Association's absolute or relative contraindications for symptom-limited maximal exercise testing (myocardial infarction, aortic or coronary artery stenosis, heart failure, pulmonary embolism or deep vein thrombosis, inflammation of the heart (myocarditis, pericarditis, and\u002For endocarditis), uncontrolled cardiac arrythmia, advanced or complete electrical heart block, stroke or transient ischemia attack, blood pressure \\>200mmHg\u002F100mmHg, a cancer diagnosis other than skin cancer)\n* Unable to provide informed consent or communicate in English\n* Pregnant or breast-feeding currently or in the past 3 months\n* Mobility limitations to aerobic exercise (i.e., wheelchair, walker use, limp impeding walking)\n* Smoking cigarettes or marijuana within the past 3 months\n* Taking exogenous hormones in any format currently or in the past 3 months\n* Contraindications to research MRI (e.g., pacemaker, magnetic implants)\n* BMI exceeding 40 kg\u002Fm2\n* Extreme claustrophobia\n* Self-report \\>30 min\u002Fweek of moderate-to-vigorous intensity aerobic physical activity\n* Following a diet that largely restricts entire food groups or time of eating (e.g., vegan, ketogenic, carnivore, one meal a day) in last 3 months\n* Students in classes or labs of the professors who are involved in the study\n* Experienced significant weight loss (i.e., \\>5 kg) in past 3 months\n* Currently taking weight loss medications\n* Diagnosed history of an eating disorder or self-report of potential undiagnosed eating disorder\n* Plans to be away\u002Funavailable for a substantial period of the intervention overall (i.e., \\>4 weeks throughout the 6 months or \\>2 weeks within the first 12 weeks of the intervention).\n* Allergies to local anesthetics","30 Years",{"count":82,"type":20},180,[23],"This study aims to produce new evidence, specific to women, on the efficacy and mechanisms of exercise and diet for cardiometabolic risk reduction in pre and postmenopausal women. Using a 3-arm randomized controlled trial (RCT) with equal recruitment and stratification by menopausal status to 6 months of: 1) exercise following Health Canada guidelines; 2) the same exercise plus counselling to follow Canada's Dietary Guidelines to improve diet quality; or 3) stretching group, this study will answer the following questions:\n\n* How does the impact of exercise compare among each of the causal links between physical inactivity and cardiometabolic disease in women?\n* What is the effect modification of adding a diet quality intervention to exercise?\n* What is the effect modification by menopausal status?\n\nThe investigators hypothesize that exercise adaptations will be: 1) largest peripherally, including Matsuda index (primary outcome), Homeostatic Model Assessment of Insulin Resistance (HOMA-IR), arteriovenous oxygen difference (avO2diff), and visceral fat, compared to centrally (stroke volume (SV), endothelial function, aortic stiffness), 2) blunted or absent in post vs premenopause; 3) enhanced by the addition of diet quality which will be essential or additive for Matsuda index, metabolic syndrome, Framingham cardiovascular disease (CVD) risk, cytokines and adipokines, thigh myosteatosis, muscle mass, peak oxygen uptake (VO2peak), 4) enhanced by adding diet quality in more outcomes postmenopause.",[31,61],[87],"Primary Prevention","2025-09-11",{"date":90,"type":38},"2025-09-17",{"date":92,"type":38},"2024-05-03",{"date":94,"type":20},"2028-08-01",{"name":71,"class":45},{"id":97,"slug":98,"hasResults":11,"nctId":99,"briefTitle":100,"officialTitle":101,"acronym":102,"eligibilityCriteria":103,"healthyVolunteers":104,"sex":105,"minAge":106,"maxAge":107,"enrollmentInfo":108,"targetDuration":4,"studyType":110,"phases":4,"briefSummary":111,"conditions":112,"keywords":115,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":123,"lastUpdatePostDateStruct":124,"startDateStruct":126,"completionDateStruct":128,"leadSponsor":130,"locationsCount":72},"100535522","diet-induced-changes-in-genetic-material-100535522","NCT06252922","Diet-Induced Changes in GEnetic Material","A Pilot Study to Examine Metabolic Flexibility as a Mechanism for Diet- Induced Epigenetic Alterations in Male Gametes","DIG 'EM","Inclusion Criteria:\n\n* Male based on biological sex\n* Age 20-35 years\n* BMI between 18.5 and 24.9 kg\u002Fm2\n* White\u002FCaucasian\n* Willing to consume pre-prepared meals\n* Willing to wear an accelerometer and continuous glucose monitor (CGM)\n* Willing to track diet intake\n* Willing to stay 24 hours, including overnight in a research clinic\n* Willing to provide blood and sperm samples\n* Willing to consent to whole-genome sequencing of DNA\n\nExclusion Criteria:\n\n* Unstable weight in the last 3 months (±5% weight loss or gain)\n* Shift work or working in a factory setting\n* Habitual smoking or use of tobacco products, including vaping, within the past 6 months.\n* History of clinically diagnosed diabetes\n* Hypertension (\\>140\u002F90 mmHg measured at screening)\n* Has undergone bariatric surgery\n* History of cardiovascular disease, neurological disease, or other chronic diseases, including cancer\n* History of human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS)\n* Adherence to special or restrained diets (e.g., low-CHO, low-fat, or vegetarian\u002Fvegan diets) or food allergies associated with study foods.\n* Currently engaging in \\>150 minutes moderate-intensity or \\>75 minutes of vigorous-intensity physical activity each week\n* Drinking more than 14 servings of beer or alcohol per week\n* Depressive (Score ≥10), anxiety (Score ≥8), and stress (Score≥15) symptomology (Score ≥16) from the 42-item Depression, Anxiety, Stress Scales (DASS)",true,"MALE","20 Years","35 Years",{"count":109,"type":20},10,"OBSERVATIONAL","This is a pilot study in 10 men to test the hypothesis that perturbations in substrate flux and the circulating metabolic and pro-inflammatory milieus during a high-fat diet paradigm will modulate DNA methylation of genes in sperm associated with obesity and cardiometabolic dysfunction.",[113,114,31],"Diet, Healthy","Body Weight",[116,117,118,119,120,121,122],"Healthy Weight","High-Fat Diet","Sperm DNA Methylation","Metabolic Flexibility","DNA Damage","Substrate Flux","Preconception","2025-05-27",{"date":125,"type":38},"2025-05-31",{"date":127,"type":38},"2023-11-11",{"date":129,"type":20},"2026-12-30",{"name":131,"class":45},"Pennington Biomedical Research Center",{"id":133,"slug":134,"hasResults":11,"nctId":135,"briefTitle":136,"officialTitle":136,"acronym":4,"eligibilityCriteria":137,"healthyVolunteers":104,"sex":16,"minAge":17,"maxAge":80,"enrollmentInfo":138,"targetDuration":4,"studyType":21,"phases":139,"briefSummary":140,"conditions":141,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":145,"lastUpdatePostDateStruct":146,"startDateStruct":148,"completionDateStruct":150,"leadSponsor":152,"locationsCount":72},"100509355","the-effects-of-an-obesogenic-lifestyle-in-recreationally-active-young-adults-100509355","NCT05912348","The Effects of an Obesogenic Lifestyle in Recreationally Active, Young Adults","Inclusion Criteria:\n\n* 18-30 years of age\n* Recreationally active completing 75-150 minutes of moderate-to-vigorous intensity exercise (\\>2 days\u002Fweek).\n* Fair cardiorespiratory fitness levels (Men: VO2\\>38.4 ml\u002Fkg\u002Fmin; Women: VO2\\>32.6 ml\u002Fkg\u002Fmin).\n\nExclusion Criteria:\n\n* Hypertension (resting or diagnosed)\n* Impaired fasting blood glucose (\\>100mg\u002FdL)\n* Diagnosed cardiovascular disease\n* Diagnosed diabetes\n* Diagnosed cancer\n* Diagnosed chronic kidney disease\n* Diagnosed musculoskeletal disorders that prevents the individual from exercising on a bike.",{"count":57,"type":20},[23],"This clinical trial aims to learn about the alterations in insulin resistance and metabolic flexibility following a transition to an obesogenic lifestyle in fit young men and women. The main questions it aims to answer are:\n\n1. Does adding excess carbohydrates when transitioning to a sedentary lifestyle promote insulin resistance and impaired 24hr glucose regulation in healthy men and women?\n2. Does adding excess carbohydrates when transitioning to a sedentary lifestyle lower the body's ability to break down fats and carbohydrates in healthy men and women?\n3. Does the added physical activity blunt shifts in carbohydrate and fat oxidation in healthy men and women?",[142,143,144,31],"Insulin Resistance","Impaired Glucose Tolerance","Obesity","2024-07-16",{"date":147,"type":38},"2024-07-17",{"date":149,"type":38},"2023-02-08",{"date":151,"type":20},"2026-09-30",{"name":153,"class":45},"University of New Hampshire",{"id":155,"slug":156,"hasResults":11,"nctId":157,"briefTitle":158,"officialTitle":159,"acronym":160,"eligibilityCriteria":161,"healthyVolunteers":104,"sex":16,"minAge":4,"maxAge":17,"enrollmentInfo":162,"targetDuration":4,"studyType":110,"phases":4,"briefSummary":164,"conditions":165,"keywords":171,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":173,"lastUpdatePostDateStruct":174,"startDateStruct":176,"completionDateStruct":178,"leadSponsor":180,"locationsCount":72},"100342698","offspring-born-to-mothers-with-polycystic-ovary-syndrome-in-guangzhou-cohort-study-100342698","NCT03742011","Offspring Born to Mothers With Polycystic Ovary Syndrome in Guangzhou Cohort Study","Health of Offspring Born to Mothers With Polycystic Ovary Syndrome in Guangzhou Cohort Study","PCOS-BIG","Inclusion Criteria:\n\n* Offspring born to women diagnosed with PCOS\n* Offspring born to women with \\\u003C20 weeks of gestation, intended to eventually deliver in Guangzhou Women and Children's Medical Center\n* Permanent residents or families intended to remain in Guangzhou for ≥3 years\n\nExclusion Criteria:\n\n* None",{"count":163,"type":20},2000,"The Offspring Born to Mothers with Polycystic Ovary Syndrome in Guangzhou Cohort study (PCOS-BIG) was established to investigate the short- and long-term effects of intrauterine exposure to maternal PCOS on the health of offspring in Guangzhou, China. Data are collected regarding maternal PCOS subtypes, nursing, diet and education as well as health outcomes in their later life. Biological samples including blood and tissue samples are also collected from participants.",[166,167,168,169,142,170,31],"PCOS","Offspring, Adult","Hyperandrogenism","Epigenetics","Endocrine Disorder",[166,168,169,172],"Glucolipid metabolism disorder","2024-02-22",{"date":175,"type":38},"2024-02-26",{"date":177,"type":38},"2012-02-01",{"date":179,"type":20},"2038-12-31",{"name":181,"class":45},"Guangzhou Women and Children's Medical Center",{"id":183,"slug":184,"hasResults":11,"nctId":185,"briefTitle":186,"officialTitle":187,"acronym":4,"eligibilityCriteria":188,"healthyVolunteers":104,"sex":55,"minAge":106,"maxAge":189,"enrollmentInfo":190,"targetDuration":4,"studyType":21,"phases":192,"briefSummary":193,"conditions":194,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":198,"lastUpdatePostDateStruct":199,"startDateStruct":201,"completionDateStruct":203,"leadSponsor":205,"locationsCount":72},"100440058","insulin-sensitivity-after-breast-cancer-100440058","NCT05010356","Insulin Sensitivity After Breast Cancer","Study of Molecular Causes of Metabolic Disorders in Obese Premenopausal Women After Breast Cancer","Inclusion Criteria:\n\n* Premenopausal women operated for breast cancer and after completing adjuvant chemotherapy and no earlier than 3 weeks after its termination\n* BMI: 25-30\n* Healthy controls will be included matched by gender, weight, age, and level of physical activity to the patient group included as subjects\n\nExclusion Criteria:\n\n* Known postmenopause occurred at the time of diagnosis of breast cancer\n* Alcohol intake of\\> 7 items \u002F week\n* Smoker\n* Already known Type 2 diabetes mellitus or metabolic syndrome and medical treatment thereof.\n* Cardiovascular disease and its medical treatment\n* Impaired mobility","45 Years",{"count":191,"type":20},24,[23],"Epidemiological studies have revealed that 60-80% of women with breast cancer (BC) develop metabolic disorders that are similar to those observed in conditions like type 2 diabetes. These metabolic disorders, including insulin resistance, obesity, hyperinsulinemia, and glucose intolerance, are associated with increased BC recurrence and mortality. Skeletal muscle is the major site of glucose uptake in humans. The aims of the present project are to 1) determine the involvement of insulin resistance in skeletal muscle in the metabolic disorders prevalent in BC survivors, 2) identify BC-and\u002For treatment-induced molecular changes in skeletal muscle from BC survivors .",[195,196,197,31],"Insulin Sensitivity\u002FResistance","Breast Cancer","Survivorship","2021-08-10",{"date":200,"type":38},"2021-08-18",{"date":202,"type":20},"2021-08",{"date":204,"type":20},"2026-09",{"name":206,"class":45},"University of Copenhagen"]