[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"metabolic-syndrome-risk-factors\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:metabolic-syndrome-risk-factors":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,42],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100633963","effects-and-mechanisms-of-dietary-carbohydrate-intake-and-quality-on-glucose-and-lipid-metabolism-100633963",false,"NCT07533513","Effects and Mechanisms of Dietary Carbohydrate Intake and Quality on Glucose and Lipid Metabolism","Inclusion Criteria:\n\n* Male and female aged 18 - 65 years;\n* BMI 20 - 35 kg\u002Fm2;\n* Consent to be randomly assigned to an intervention or control group;\n* Willingness to eat the food and beverages provided in the study;\n* Patients with or at high risk of metabolic syndrome, and the diagnostic criteria of metabolic syndrome were based on the Chinese Guidelines for the Prevention and Treatment of diabetes (2024 edition).\n\nExclusion Criteria:\n\n* Use of medications that affect blood glucose metabolism;\n* Familial hyperlipidemia, or use of drugs that affect lipid metabolism;\n* Long-term or current use of nonsteroidal anti-inflammatory drugs, antibiotics, antihistamines, or immunomodulatory drugs, and unable to stop taking these drugs within 72 h before the start of the study;\n* Use of hormonal medications such as anticoagulants, anabolic steroids, and hydrocortisone;\n* Have a history of serious illness, or are in the acute stage of cardiovascular, renal, thyroid, gastrointestinal, hepatobiliary, immunologic, respiratory, neurological, musculoskeletal, psychiatric, infectious, and malignant diseases, and are receiving treatment or use of related drugs;\n* Self-reported weight gain or loss of more than 7 kg in the 6 months before enrollment;\n* Vegetarian;\n* Have food allergies or other problems that may affect food intake;\n* Unable to consume only the food and beverages provided in the study;\n* Drink alcohol more than 2 times per day, more than 14 times per week, and unwillingness to stop drinking during the study;\n* Participate in a weight-loss program;\n* Unwillingness to maintain weight throughout the study;\n* Females who have given birth within the past year, are pregnant or plan to become pregnant within 6 months, are breastfeeding;\n* Intend to participate in other dietary intervention studies and drug use studies in the next 4 months;\n* Poor venous blood access;\n* Any other that the physician assessed as unsuitable for the trial conditions.",true,"ALL","18 Years","65 Years",{"count":20,"type":21},20,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study aimed to explore the effects of quantity and quality of dietary carbohydrate intakes on glucose and lipid levels and metabolism, as well as gut microbiota by a randomized crossover controlled intervention trial.",[27,28],"Metabolic Syndrome (MetS)","Metabolic Syndrome Risk Factors","NOT_YET_RECRUITING","2026-04-09",{"date":32,"type":33},"2026-04-16","ACTUAL",{"date":35,"type":21},"2026-04-13",{"date":37,"type":21},"2028-03-30",{"name":39,"class":40},"Sun Yat-sen University","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":46,"acronym":47,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":22,"phases":52,"briefSummary":53,"conditions":54,"keywords":55,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":41},"100620193","assessing-the-effect-of-an-antioxidant-rich-diet-on-metabolic-syndrome-risk-using-the-dietary-antioxidant-index-100620193","NCT07354438","Assessing the Effect of an Antioxidant-Rich Diet on Metabolic Syndrome Risk Using the Dietary Antioxidant Index","AD-MetS-DAI","Inclusion Criteria:\n\n* Adults aged 18-45 years\n* Metabolic syndrome risk (abdominal obesity \\& elevated BP as per NCEP ATP III criteria).\n* Low fruit \\& veg intake (\\\u003C5 serv.\u002Fday) as per WHO.\n* Willing to follow an intervention\n* Non-pregnant or lactating\n* Not diagnosed with malabsorption syndrome or chronic illness\n\nExclusion Criteria:\n\n* Individuals \\\u003C 18 years or \\> 45 years\n* Not at risk of metabolic syndrome.\n* Adequate intake of fruits \\& veg (≥ 5 serv.\u002Fday) as per WHO\n* Not willing\n* Pregnant or lactating\n* Diagnosed with malabsorption syndrome or chronic illness","45 Years",{"count":51,"type":21},55,[24],"Metabolic syndrome (MetS) is a cluster of metabolic disorders characterized by elevated levels of blood glucose, hypertension, dyslipidemia, and abdominal obesity. Globally, it is a major public health concern. International studies have linked higher Dietary Antioxidant Index with reduced risk of MetS, as antioxidants play a role in lowering the risk of MetS by reducing oxidative stress, a key contributor to its pathophysiology. Exploring this link in Pakistan can provide valuable insights for dietary strategies to reduce the risk of MetS.",[28],[56,57,58],"Antioxidants","Dietary antioxidant index","Metabolic Syndrome risk","RECRUITING","2026-01-14",{"date":62,"type":33},"2026-01-21",{"date":64,"type":21},"2026-01-01",{"date":66,"type":21},"2026-04-15",{"name":68,"class":40},"University of Veterinary and Animal Sciences, Lahore - Pakistan"]