[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"metabolism-disorder-lipid\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:metabolism-disorder-lipid":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,59],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":33,"overallStatus":46,"whyStopped":4,"lastUpdateSubmitDate":47,"lastUpdatePostDateStruct":48,"startDateStruct":51,"completionDateStruct":53,"leadSponsor":55,"locationsCount":58},"100541915","metabolic-flexibility-and-autonomic-control-after-muscle-power-vs-metabolic-power-training-in-postmenopausal-oncological-women-the-power-health-study-100541915",false,"NCT06336070","Metabolic Flexibility and Autonomic Control After Muscle Power vs Metabolic Power Training in Postmenopausal Oncological Women: the POWER Health Study","Postmenopausal Oncological Women Exercising for Recover Their Health. Associations and Changes in Metabolic Flexibility and Autonomic Control After Two Training Programs (Muscle Power vs Metabolic Power): the POWER Health Study","POWER Health","Inclusion Criteria:\n\n* Patients diagnosed of relapse free-cancer (RFC) or patients not diagnosed of any cancer at least the last 15 years (CG)\n* Aged between 35 and 75 years\n* Diagnostic of breast cancer (i.e., including ductal carcinoma, invasive carcinoma, triple negative; RFC) or physiological menopause (CG)\n* Not participating in a nutritional\u002Fdietary intervention\n* Not being physically active (i.e., not to be participating in any physical exercise program in the last 3 months, or performing less than 600 metabolic equivalents (METS)\u002Fweek of moderate-vigorous physical activity).\n* To be capable and willing to provide informed consent\n* Not to suffer from any specific condition that may impede testing of the study hypothesis or make it unsafe to engage in the exercise intervention (i.e., determined by the research staff).\n\nExclusion Criteria:\n\n* Medical contraindication for being engaged in an exercise.\n* Additional surgery planned within the intervention\n* Consuming usually betablocker or any drugs alterning nervous system functioning\n* History of another primary invasive cancer (RFC) or suffer a serious chronic illness (CG)\n* To present any of the following cardiac conditions: (i) myocardial infarction or coronary revascularization procedure within prior 3 months, (ii) uncontrolled hypertension (i.e., systolic ≥180 mmHg or diastolic ≥100 mmHg), (iii) uncontrolled arrhythmias (iv) valvular disease clinically significant, (v) decompensated heart failure or (vi) to suffer from known aortic aneurysm.","FEMALE","35 Years","75 Years",{"count":21,"type":22},56,"ESTIMATED","INTERVENTIONAL",[25],"NA","POWER Health is a randomized clinical trial with a two-arm parallel design whose objectives are 1) to study metabolic flexibility and autonomic function (both capacities that describe cardiovascular health) in a sample of postmenopausal oncological women vs postmenopausal untreated controls (CT); and 2) to analyze the impact of two different 8-week physical exercise supervised interventions: HIIT training vs strength training focused on muscle power, on both cardiovascular capacities in these populations.",[28,29,30,31,32],"Breast Cancer Female","Cardiometabolic Syndrome","Metabolism Disorder, Lipid","Autonomic Dysfunction","Cardiovascular Diseases in Old Age",[34,35,36,37,38,39,40,41,42,43,44,45],"Metabolic Flexibility","Heart Rate Variability","Muscle Power","Resting metabolic Rate","Lactate","High Intensity Interval Training","Strength Training","Breast Cancer","Ageing","Menopause","Female","Exercise Training","RECRUITING","2024-04-02",{"date":49,"type":50},"2024-04-04","ACTUAL",{"date":52,"type":50},"2024-01-01",{"date":54,"type":22},"2028-12-31",{"name":56,"class":57},"University of Valencia","OTHER",1,{"id":60,"slug":61,"hasResults":11,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":4,"eligibilityCriteria":65,"healthyVolunteers":66,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":4,"studyType":72,"phases":4,"briefSummary":73,"conditions":74,"keywords":77,"overallStatus":46,"whyStopped":4,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":58},"100337158","the-biological-rhythm-of-human-metabolite-100337158","NCT03669809","The Biological Rhythm of Human Metabolite","Association Between Serum Metabolism Markers and Biological Rhythm","Inclusion Criteria:\n\n* Male or female；\n* Aged of 18 to 30 years old;\n\nExclusion Criteria:\n\n* Presence of pituitary\u002Fhypothalamic disorders, polycystic ovarian syndrome， thyroid disorders, hypertension, malignant tumor, cardiac insufficiency，hepatic or renal insufficiency, gastrointestinal disorders and acute infection;\n* Receiving psychotropic or hormonal medications including hormonal contraception and hormone therapies;\n* Taking lipid-lowering agents or hypoglycemic agents and other drugs that known to influence cardiovascular health;\n* Pregnancy or lactation women;\n* Obviously poor compliance.",true,"ALL","18 Years","30 Years",{"count":71,"type":22},200,"OBSERVATIONAL","The circadian regulation in mammals have been known for a long time. A special group of clock genes, organized in feedback loops, are responsible for the circadian regulation in both the SCN and peripheral organs. The central clock is mainly entrained by the light-dark cycle, while the peripheral ones in organs such as liver and intestine, are more influenced by the feeding-fasting cycles. The coordination of central and peripheral clocks is thought to be essential in the maintenance of physiological homeostasis.This study aim to investigate the association between biological rhythm and metabolism.",[75,76,30],"Rhythm Nodal","Metabolism and Nutrition Disorder",[78,79,80,81,82,83],"biological rhythm","metabolism","hormone","lipid","bile acids","obesity","2022-05-10",{"date":86,"type":50},"2022-05-11",{"date":88,"type":4},"2011-05-01",{"date":90,"type":22},"2050-05-01",{"name":92,"class":93},"Shandong Provincial Hospital","OTHER_GOV"]