[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"metacarpal-fracture\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:metacarpal-fracture":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,42,72],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100638956","intramedullary-screw-fixation-versus-closed-reduction-and-percutaneous-pinning-with-cast-immobilization-100638956",false,"NCT07616947","Intramedullary Screw Fixation Versus Closed Reduction and Percutaneous Pinning With Cast Immobilization","Intramedullary Screw Fixation Versus Closed Reduction and Percutaneous Pinning With Cast Immobilization in the Treatment of Phalangeal and Metacarpal Fractures: A Randomized Control Trial","GRIP","Inclusion Criteria:\n\nThe MC arm:\n\n* surgical management within 10 days of injury\n* extraarticular fractures, clinical scissoring\n* sagittal angulation in accordance with accepted norms (Table 1)\n* shortening \\>5mm, translation \\>50%.\n\nThe phalangeal arm:\n\n* surgical management within 10 days of injury\n* extraarticular fractures, clinical scissoring\n* sagittal angulation \\>20°\n* shortening \\>2mm\n* translation \\>50%.\n\nExclusion Criteria:\n\n* \\\u003C 18 years old\n* unable to read English, provide consent, or return to follow-up.\n* Injuries with concomitant soft tissues loss, tendon injury, nerve injury, infection, or fractures with severe comminution\n* history of prior surgical management of a fracture of the ipsilateral hand","ALL","18 Years",{"count":20,"type":21},100,"ESTIMATED","INTERVENTIONAL",[24],"NA","Broken bones in the hand are common injuries that can make it hard to move fingers, grip objects, and return to work. When these breaks happen in the long bones of the hand (called metacarpals and phalanges), surgery is often needed to hold the bones in the right place while they heal.\n\nThere are a few different ways surgeons can fix these broken bones. Two common methods are:\n\nCRPP (Closed Reduction and Percutaneous Pinning): The bones are moved back into place without opening the skin, and thin metal pins are used to hold them.\n\nIMSF (Intramedullary Screw Fixation): A small screw is placed inside the bone to hold it in position.\n\nAnother approach sometimes used for larger bones in the hand is ORIF (Open Reduction and Internal Fixation), where the bone is exposed through a small incision and held with plates or screws.\n\nThis study will compare how well these methods work. Investigators want to find out if using an intramedullary screw (IMSF) helps patients heal faster and move their hands more easily compared to the other common methods (CRPP and ORIF). Investigators will look at how quickly patients regain movement, how soon they can return to work, how satisfied they are with their recovery, and whether there are any problems or complications from surgery.\n\nTo do this, investigators will run a randomized controlled trial-this means patients will be stratified based on fracture location (metacarpals or phalanges) and randomly assigned to a treatment arm. For patients with metacarpal fractures, investigators will compare IMSF vs CRPP vs ORIF using a dorsal plate. For patients with proximal or middle phalangeal fractures investigators will compare IMSF to CRPP. Investigators will measure their recovery using both clinical tests and patient surveys over time. The results of this research will help surgeons choose the best and safest way to treat hand fractures so patients can heal faster and get back to their daily lives sooner",[27,28],"Metacarpal Fracture","Phalanx Fracture","NOT_YET_RECRUITING","2026-05-26",{"date":32,"type":33},"2026-06-01","ACTUAL",{"date":35,"type":21},"2026-09-01",{"date":37,"type":21},"2029-10-01",{"name":39,"class":40},"Spencer B Chambers","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":22,"phases":51,"briefSummary":52,"conditions":53,"keywords":59,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":41},"100613185","evaluation-of-diaphragmatic-function-after-interscalene-block-with-liposomal-bupivacaine-100613185","NCT07263295","Evaluation of Diaphragmatic Function After Interscalene Block With Liposomal Bupivacaine","Evaluation of Diaphragmatic Function After Interscalene Brachial Plexus Block With Liposomal Bupivacaine: A Cohort Study","Inclusion Criteria:\n\n* Patients undergoing upper limb surgery scheduled for interscalene brachial plexus block\n* Aged ≥ 18 years\n* American Society of Anesthesiologists (ASA) physical status I-III\n\nExclusion Criteria:\n\n* Known allergy or intolerance to amide local anesthetics\n* Nerve injury in the upper limb on the surgical side\n* Coagulopathy\n* Used opioid medications continuously for more than 3 weeks before surgery\n* History of pulmonary disease and a pulse oxygen saturation (SpO₂) \\\u003C 95% (measured after 5 minutes of rest at room temperature without oxygen supplementation, using a transcutaneous pulse oximeter)\n* Refuse to participate or are deemed unsuitable for this trial by the researchers\n\nWithdrawal Criteria:\n\n* Patients voluntarily withdrew their informed consent\n* Surgery was canceled or the anesthesia method was changed due to surgical factors before interscalene brachial plexus block",{"count":50,"type":21},120,[24],"The study aims to evaluation the effects of Liposomal Bupivacaine on diaphragmatic function in patients undergoing upper limb surgery who receive Interscalene Brachial Plexus Block. A total of 120 eligible patients will be enrolled and divided into two groups: Group A will receive 20ml of 0.5% Hydrochloride Bupivacaine , while Group B will receive 10ml of 0.5% Hydrochloride Bupivacaine plus 10ml of Liposomal Bupivacaine. Assessments of diaphragmatic function, pulmonary function, and pain intensity will be performed before the block and at different time points after the block, with follow-up for adverse events. The study is scheduled to run from September 2025 to September 2026, with strict adherence to privacy protection and ethical guidelines.",[54,27,55,56,57,58],"Diaphragmatic Function","Radius Fracture","Peripheral Nerve Neurolysis","Chronic Ulcer","Upper Extremity Ligament Injury",[60,61,62],"Interscalene brachial plexus block","Liposomal Bupivacaine","Hemidiaphragmatic paralysis","2025-11-30",{"date":65,"type":33},"2025-12-04",{"date":67,"type":21},"2025-12-05",{"date":69,"type":21},"2026-12-20",{"name":71,"class":40},"Zhejiang University",{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":80,"enrollmentInfo":81,"targetDuration":4,"studyType":22,"phases":83,"briefSummary":84,"conditions":85,"keywords":4,"overallStatus":87,"whyStopped":4,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":41},"100550644","elastic-nail-versus-screw-for-intramedullary-fixation-of-displaced-fractures-of-the-fifth-metacarpal-neck-100550644","NCT06449755","Elastic Nail Versus Screw for Intramedullary Fixation of Displaced Fractures of the Fifth Metacarpal Neck","Elastic Nail Versus Screw for Closed Reduction and Intramedullary Fixation of Displaced Fractures of the Fifth Metacarpal Neck: a Randomised Controlled Trial","Boxerfx","Inclusion Criteria:\n\n* Patients aged 18-60 years with displaced fifth metacarpal fractures with angulation greater than 30 degrees\n\nExclusion Criteria:\n\n* Open fracture\n* Patients with multiple injuries\n* History of hand surgery\n* Intraarticular metacarpal neck fractures","60 Years",{"count":82,"type":21},46,[24],"The goal of this clinical trial is to compare two different intramedullary fixation technique in patient diagnosed with deplased fifth metacarpal neck fracture. The main questions it aims to answer are:\n\n* Can percutaneous screw application be a more stable fixation method than intramedullary elastic nail application?\n* Can screw application create a significant difference in the recovery of grip strength in the early period compared to elastic nail application? Patients will be followed up at the 1st week, 1st month and 3rd month postoperatively. Functionality will be evaluated with Quick DASH score at the 3rd month. At the 1st and 3rd month controls, grip strength will be evaluated. At the same time, metacarpal shortening and angulations will be measured on x-ray. Researchers will compare percutaneous screw and elastic nail group to see grip strength, healing time and radiologic parameter difference.",[27,86],"Boxer's Fracture","RECRUITING","2024-06-04",{"date":90,"type":33},"2024-06-10",{"date":92,"type":33},"2023-09-01",{"date":94,"type":21},"2025-02-01",{"name":96,"class":40},"Istanbul University"]