[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"metastases-to-liver\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:metastases-to-liver":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,46],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":21,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":31,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100637253","china-metastatic-liver-cancer-clinical-registry-cohort-database-100637253",false,"NCT07602504","China Metastatic Liver Cancer Clinical Registry Cohort Database","Inclusion Criteria:\n\n1. Patients with histologically or radiologically confirmed metastatic liver cancer.\n2. Age ≥ 18 years.\n3. Patients who have voluntarily signed the informed consent form.\n4. Patients with complete baseline clinical data.\n\nExclusion Criteria:\n\n1. Patients with primary liver cancer (e.g., hepatocellular carcinoma).\n2. Patients with other malignant tumors that may interfere with the evaluation of liver metastasis.\n3. Patients who have previously participated in other interventional clinical trials.\n4. Patients with severe cognitive disorders or communication barriers that prevent informed consent.\n5. Patients with incomplete or missing key clinical data.","ALL","18 Years","80 Years",{"count":19,"type":20},2000,"ESTIMATED","10 Years","OBSERVATIONAL","This study is led by the Department of Hepatobiliary Surgery of the First Affiliated Hospital of the University of Science and Technology of China (USTC), in close collaboration with multiple participating centers nationwide. The primary objective is to establish a standardized, large-scale clinical cohort database specifically for metastatic liver cancer. By collecting comprehensive data on patient demographics, primary tumor characteristics, systemic therapies, and local interventions, this registry aims to elucidate the clinical patterns and prognostic factors of secondary liver malignancies. This database will serve as a robust platform for conducting high-quality real-world studies and advancing evidence-based clinical research in the management of metastatic liver cancer.",[25,26,27,28,29,30],"Liver Metastases","Metastases to Liver","Liver Cancer","Neoplasms","Liver Diseases","Colorectal Cancer Metastatic",[32],"Liver Metastases; Metastatic Colorectal Cancer","RECRUITING","2026-05-16",{"date":36,"type":37},"2026-05-22","ACTUAL",{"date":39,"type":20},"2026-06-01",{"date":41,"type":20},"2036-05-31",{"name":43,"class":44},"Anhui Provincial Hospital","OTHER_GOV",3,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":55,"phases":56,"briefSummary":58,"conditions":59,"keywords":62,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":77},"100611178","15-vs-45-minute-pringle-maneuver-in-liver-cancer-resection-randomized-noninferiority-trial-100611178","NCT07237204","15 vs 45 Minute Pringle Maneuver in Liver Cancer Resection: Randomized Noninferiority Trial","A Prospective, Randomized Noninferiority Trial Comparing 15- and 45-minute Pringle Maneuvers During Liver Resection for Oncologic Indications.","Inclusion Criteria:\n\n* Diagnosis of a primary or secondary malignant liver tumor.\n* Age \\> 18 years.\n* Patient deemed eligible for liver resection.\n* WHO performance status ≤ 2.\n* Ability to provide written informed consent.\n\nExclusion Criteria:\n\n* Liver cirrhosis.\n* Liver dysfunction classified as Child-Pugh class B or C.\n* Repeat hepatectomy.\n* Prior ablation or chemoembolization of hepatic lesions.\n* Prior portal vein branch embolization.\n* Planned or performed ALPPS procedure.\n* Concomitant resection of any organ other than the gallbladder during the same operation.",{"count":54,"type":20},600,"INTERVENTIONAL",[57],"NA","The goal of this clinical trial is to evaluate the safety of two durations of the Pringle maneuver in adults undergoing elective liver resection for malignant tumors. The main questions it aims to answer are:\n\nIs the incidence of post-hepatectomy liver failure different between 15-minute and 45-minute Pringle maneuver durations?\n\n* Do the durations differ in operative time or intraoperative blood loss?\n* Researchers will compare patients randomized 1:1 to 15 minutes vs 45 minutes of Pringle clamping to see if outcomes are non-inferior between groups.\n\nParticipants will:\n\n* Undergo standard oncologic hepatectomy with the assigned Pringle duration.\n* Receive routine perioperative assessments, including laboratory tests and clinical evaluations.\n* Attend follow-up visits at approximately 6 months, 1 year, and 3 years after surgery.",[60,26,61],"Liver Cancer, Adult","Liver Malignant Tumors",[63,64,65],"Pringle manouver","Liver malignancy","Liver resection","NOT_YET_RECRUITING","2025-11-14",{"date":69,"type":37},"2025-11-19",{"date":71,"type":20},"2025-12-01",{"date":73,"type":20},"2030-11-01",{"name":75,"class":76},"Medical University of Warsaw","OTHER",1]