[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"metastatic-bone-disease\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:metastatic-bone-disease":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,42],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":27,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100602877","musculoskeletal-cancers-remote-monitoring-and-care-100602877",false,"NCT07129226","Musculoskeletal Cancers Remote Monitoring and Care","Inclusion Criteria:\n\n* primary sarcoma or metastatic bone disease of the lower extremities or pelvis.\n* undergoing evaluation for (or have recently undergone) non-surgical or surgical intervention.\n* recent history of home ambulation.\n\nExclusion Criteria:\n\n* under 18 years of age at the time of study enrolment\n* inability to comprehend consent form and give informed consent\n* no access to a smartphone (iOS or Android) to interface with watch application\n* tattoos located on the skin of the wrist or forearm where the watch will be placed or other skin conditions preventing adequate sensor function\n* amputation or other disease of the arm or skin that prevents wear of a smart-watch device\n* inability to tolerate watch for at least 12 hours per day on at least 80% of days in a four-week period","ALL","18 Years",{"count":18,"type":19},60,"ESTIMATED","INTERVENTIONAL",[22],"NA","This study aims to evaluate how walking stability and the ability to perform daily activities change during cancer treatment, and whether a smartwatch can detect these changes. The goal is to develop proactive, personalized tools that automatically monitor treatment response and predict potential complications. To support future implementation, the study will assess the feasibility of wearing a smartwatch for at least 12 hours per day, using a mobile application, and completing weekly questionnaires among patients with primary osteosarcoma or metastatic bone disease.",[25,26],"Osteosarcoma","Metastatic Bone Disease",[28],"prophylactic surgery","RECRUITING","2026-06-03",{"date":32,"type":33},"2026-06-04","ACTUAL",{"date":35,"type":33},"2026-02-11",{"date":37,"type":19},"2026-08",{"name":39,"class":40},"Case Comprehensive Cancer Center","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":50,"targetDuration":4,"studyType":20,"phases":52,"briefSummary":53,"conditions":54,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":56,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":64},"100582424","proximal-femur-reconstruction-or-internal-fixation-for-metastases-perform-trial-100582424","NCT06863129","Proximal FEmur Reconstruction or Internal Fixation fOR Metastases (PERFORM) Trial","Proximal FEmur Reconstruction or Internal Fixation fOR Metastases (PERFORM) Randomized Controlled Trial","PERFORM","Inclusion Criteria:\n\n* Life expectancy of at least 6 months\n* Lesions in the proximal femur (femoral neck, intertrochanteric region, subtrochanteric region, and combinations thereof)\n* Low or intermediate risk for perioperative morbidity and\u002For mortality\n* No more than 75% and no less than 25% bone loss\n* Mutual (patient and physician) decision to perform surgical management of an impending or realized pathologic fracture due to MBD of the proximal has been made.\n\nExclusion Criteria:\n\n* Lesions isolated to the femoral neck\n* Lesion with any femoral head involvement\n* High risk for perioperative morbidity and\u002For mortality\n* Multidisciplinary decision that resection of the entire lesion would be indicated",{"count":51,"type":19},334,[22],"The goal of this clinical trial is to find out if removing and replacing part of the hip bone works better than using metal hardware to stabilize the bone in patients whose cancer has spread to the hip. The main questions are:\n\n1. Does removing and replacing part of the bone work better than just stabilizing it with metal hardware?\n2. Does removing and replacing the bone help reduce problems like cancer coming back or the metal hardware breaking?\n\nResearchers will compare two treatments: using metal rods and plates to stabilize the bone (internal fixation) versus removing part of the bone and possibly replacing the hip joint (resection and reconstruction) to see if the second option causes fewer problems.\n\nParticipants will:\n\n* Be randomly assigned to one of two groups (internal fixation or resection and reconstruction).\n* Have one of the two surgeries based on which group they're in.\n* Go to follow-up appointments with the study doctor at 2 weeks, 6 weeks, 4 months, 6 months, 9 months, and 12 months after surgery.",[26],"2025-11-07",{"date":57,"type":33},"2025-11-10",{"date":59,"type":33},"2025-02-01",{"date":61,"type":19},"2030-06-01",{"name":63,"class":40},"Michelle Ghert, MD",6]