[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"methamphetamine\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:methamphetamine":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":5},"100573480","phase-1-methamphetamine-isomer-pharmacology-in-humans-100573480",false,"NCT06746831","Methamphetamine Isomer Pharmacology in Humans","The Low-Down on Methamphetamine Isomers: Prevalence and Pharmacology in Humans","Inclusion Criteria:\n\n* Good mental health as determined by self-reported responses to the Psychopathology Screener\n* Absence of any major cardiac, neurologic, psychiatric, oncologic, endocrine, metabolic, renal, or hepatic disease as determined by self-reported responses to the Medical History Screener\n* English-speaking (able to provide consent and complete questionnaires)\n* Written Informed Consent\n\nExclusion Criteria:\n\n* Any serious prior adverse response to sympathomimetic agents or amphetamine analogs\n* History of or current substance use disorder as determined by self-reported responses to the Internalizing, Externalizing, and Substance Use Disorder Screener\n* Pregnancy or lactation (pregnancy test, if needed)\n* Use of medications that may impact cognition or metabolism (e.g., mood stabilizers, sedatives)\n* Dependent on prohibited concomitant therapy that cannot be withheld for 48 hours prior to and during study visits.",true,"ALL","21 Years","64 Years",{"count":21,"type":22},17,"ESTIMATED","INTERVENTIONAL",[25],"PHASE1","This study is being done to understand the metabolism and impairment profile of methamphetamine (meth). Meth exists as two chemical structures that are mirror images of each other: R-meth and S-meth. S-meth is a strong central nervous system stimulant and used to treat attention deficit disorder (ADD). R-meth is not a strong central nervous system stimulant and is available over-the-counter in nasal decongestant sprays.17 healthy participants will be enrolled for 3 study visits and on study for up to 12 weeks.",[28],"Methamphetamine",[30,31,32],"pharmacology","meth","isomers","NOT_YET_RECRUITING","2026-06-29",{"date":36,"type":37},"2026-07-01","ACTUAL",{"date":39,"type":22},"2026-07",{"date":41,"type":22},"2028-03",{"name":43,"class":44},"University of Wisconsin, Madison","OTHER"]