[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"mhealth-intervention\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:mhealth-intervention":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,10,0,[8,41,65,100,129,162,184,214,241,278],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100642300","user-evaluation-think-life-100642300",false,"NCT07654127","User Evaluation Think Life","Evaluation of User Experiences With the Online Self-help Course Think Life","Inclusion Criteria:\n\n* age: 18 years or older\n* user of the online self-help course Think Life\n\nExclusion Criteria:\n\n* not meeting the inclusion criteria",true,"ALL","18 Years",{"count":20,"type":21},1000,"ESTIMATED","OBSERVATIONAL","This study aims to evaluate user experiences with the online self-help course Think Life, a suicide prevention intervention for individuals experiencing suicidal thoughts. Think Life was developed by the Flemish Centre of Expertise in Suicide Prevention (VLESP) and is freely available via Zelfmoord1813.be. The course was originally developed in 2014 and updated in 2025 to improve its look and feel, usability, and inclusiveness, without fundamental changes to its core content.\n\nThe researchers seek to better understand how users experience the updated version of Think Life, including perceived strengths, usability, and overall satisfaction with the course.\n\nUsers of the Think Life self-help course will be invited through a call displayed on the course homepage to voluntarily participate in an online user evaluation study. Interested individuals can access an online informed consent form via a public internet link hosted on REDCap. Participants who provide online informed consent and meet the inclusion criteria will automatically be redirected to the online questionnaire, which is also hosted on REDCap.\n\nApproximately 1000 participants aged 18 years or older can be included in this study. Participants are invited to complete a one-time online questionnaire with an estimated completion time of approximately 10 minutes.",[25,26,27],"Suicidal Ideation","Suicide Prevention","mHealth Intervention","NOT_YET_RECRUITING","2026-06-11",{"date":31,"type":32},"2026-06-17","ACTUAL",{"date":34,"type":21},"2026-06-01",{"date":36,"type":21},"2031-06-01",{"name":38,"class":39},"University Ghent","OTHER",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":45,"acronym":4,"eligibilityCriteria":46,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":47,"targetDuration":4,"studyType":49,"phases":50,"briefSummary":52,"conditions":53,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":4},"100643269","construction-and-feasibility-study-of-a-home-based-intelligent-symptom-management-program-for-lung-cancer-patients-receiving-combined-drug-therapy-based-on-symptom-journey-profiling-100643269","NCT07632703","Construction and Feasibility Study of a Home-Based Intelligent Symptom Management Program for Lung Cancer Patients Receiving Combined Drug Therapy Based on Symptom Journey Profiling","Inclusion Criteria:\n\n* Diagnosed with primary lung cancer confirmed by histology or cytology\n* First-time recipient of combination drug therapy, with an expected treatment course of at least 4 cycles; the combination regimen is not restricted\n* Aged 18 years or older\n* Able to use a smartphone\n* Eastern Cooperative Oncology Group performance status score of 2 or lower\n* Aware of their own diagnosis and medication regimen\n* Voluntarily agree to participate in this study\n\nExclusion Criteria:\n\n* History of mental illness or currently receiving mental health treatment\n* Diagnosis of malignancy in another organ site\n* Presence of cognitive impairment, indicated by 3 or more errors on the Short Portable Mental Status Questionnaire",{"count":48,"type":21},60,"INTERVENTIONAL",[51],"NA","The goal of this clinical trial is to develop and evaluate a home-based intelligent symptom management program based on symptom journey profiles for patients with lung cancer receiving combination drug therapy. The program will be delivered through the \"Zhihu Feifang\" WeChat mini-program and is designed to help patients monitor symptoms, receive personalized symptom management recommendations, and obtain timely support during treatment intervals at home.\n\nThe study will assess the feasibility, acceptability, and preliminary effectiveness of this intelligent symptom management program.\n\nThe main research questions are as follows: (1) Is the intelligent symptom management program feasible and acceptable for patients with lung cancer receiving combination drug therapy? (2) Compared with usual care, can the program reduce symptom burden and improve symptom self-management ability? (3) Can the program improve quality of life and help patients identify and manage symptoms more promptly during treatment intervals? Researchers will compare the intelligent symptom management program with usual care to evaluate its preliminary effectiveness. Participants will be randomly assigned to either the intervention group or the usual care group.\n\nParticipants in the intervention group will: (1) Receive usual care plus the \"Zhihu Feifang\" WeChat mini-program intervention; (2) Use the mini-program during four consecutive treatment intervals, lasting approximately 4 months; (3) Complete regular symptom assessments through the mini-program; (4) Receive personalized symptom management education, coping strategies, and risk alerts based on their symptom severity and symptom changes; (5) Receive nurse monitoring and follow-up support when needed; (6) Complete questionnaires at baseline and at follow-up time points during the study; (7) Some participants may also take part in an interview after the intervention to share their experience and suggestions.\n\nParticipants in the usual care group will receive routine follow-up care, including health education, telephone follow-up, and medical visit guidance.",[54,55,27],"Lung Neoplasms","Symptom Management","2026-06-02",{"date":58,"type":32},"2026-06-08",{"date":60,"type":21},"2026-05-25",{"date":62,"type":21},"2027-06-30",{"name":64,"class":39},"Feifei Huang",{"id":66,"slug":67,"hasResults":11,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":4,"eligibilityCriteria":71,"healthyVolunteers":11,"sex":17,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":4,"studyType":49,"phases":76,"briefSummary":77,"conditions":78,"keywords":84,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":96,"leadSponsor":98,"locationsCount":40},"100637254","improving-the-hiv-care-continuum-with-mhealth-technology-100637254","NCT07631104","Improving the HIV Care Continuum With mHealth Technology","Improving the HIV Care Continuum for Youth in the Deep South Through Mobile Health Technology","Inclusion Criteria:\n\n* Between the ages of 16 and 25 years\n* Diagnosed with HIV\n* Resident of South Carolina\n* Proficient in English\n\nExclusion Criteria:\n\n* Under 16 years of age or over 25 years of age\n* Is not a person living with HIV\n* Is not a resident of South Carolina\n* Is not proficient in English","16 Years","25 Years",{"count":75,"type":21},40,[51],"Youth living with HIV (YLHIV) face barriers to engagement and retention in HIV care, show poor medication adherence, and often fail to achieve and maintain viral suppression. YLHIV in the southern United States have particularly poor care engagement outcomes. South Carolina is one of nine states identified as \"key drivers\" of the US HIV epidemic, and HIV rates for youth in South Carolina have risen in recent years. Tailored interventions are urgently needed to improve outcomes for this population. One promising approach is to reach YLHIV via mobile Health (mHealth) technology, yet few efforts have sought to tailor mHealth interventions to the needs of YLHIV in the southern US. Thus, the scientific objective of this study is to pilot test a new mHealth intervention, called MindBodyU, designed to increase engagement\u002Fretention in care and ART adherence among YLHIV in South Carolina. In this study, investigators will evaluate the feasibility, acceptability, and initial efficacy of the mHealth intervention with a six-month pilot trial with 40 YLHIV in South Carolina.",[79,80,81,27,82,83],"HIV - Human Immunodeficiency Virus","HIV Antiretroviral Therapy (ART) Adherence","mHealth Application","Continuum of Care","Youth With HIV",[85,86,87,88,89,90,91,92],"Youth living with HIV (YLHIV)","immunology","HIV","adolescents","emerging\u002Fyoung adults","eHealth\u002FmHealth\u002Fdigital health","adherence\u002Fself-management","psychosocial intervention",{"date":94,"type":32},"2026-06-05",{"date":34,"type":21},{"date":97,"type":21},"2028-06-01",{"name":99,"class":39},"University of South Carolina",{"id":101,"slug":102,"hasResults":11,"nctId":103,"briefTitle":104,"officialTitle":105,"acronym":4,"eligibilityCriteria":106,"healthyVolunteers":11,"sex":107,"minAge":18,"maxAge":4,"enrollmentInfo":108,"targetDuration":4,"studyType":49,"phases":109,"briefSummary":110,"conditions":111,"keywords":113,"overallStatus":119,"whyStopped":4,"lastUpdateSubmitDate":120,"lastUpdatePostDateStruct":121,"startDateStruct":123,"completionDateStruct":125,"leadSponsor":127,"locationsCount":40},"100622303","social-media-psychosocial-support-group-in-reducing-alcohol-consumption-100622303","NCT07381868","Social Media Psychosocial Support Group in Reducing Alcohol Consumption","Social Media Psychosocial Support Group to Reduce Alcohol Consumption in Women: a Pilot Randomized Controlled Trial","Inclusion Criteria:\n\n* Adult women (age 18+),\n* Had a total score ≥3 in AUDIT-C \\[suggesting at-risk drinkers (i.e., binge drinking)\\]( potential distress symptoms),\n* Able to read and understand Chinese and use an instant messaging app weekly\n\nExclusion Criteria:\n\n* Women who are undergoing psychiatric\u002Fpsychological treatment","FEMALE",{"count":48,"type":21},[51],"This proposed study aims to develop and examine the feasibility, acceptability, and preliminary effectiveness of a proactive intervention model that combines brief psychological counselling, Ecological Momentary Assessment (EMA) and social media psychosocial support group to reduce alcohol consumption in women.",[112,27],"Alcohol",[114,115,116,117,118],"psychosocial support","alcohol consumption","adult women","social media","reduce alcohol intake","RECRUITING","2026-05-14",{"date":122,"type":32},"2026-05-18",{"date":124,"type":21},"2026-05-01",{"date":126,"type":21},"2026-11-30",{"name":128,"class":39},"The University of Hong Kong",{"id":130,"slug":131,"hasResults":11,"nctId":132,"briefTitle":133,"officialTitle":133,"acronym":4,"eligibilityCriteria":134,"healthyVolunteers":16,"sex":17,"minAge":135,"maxAge":136,"enrollmentInfo":137,"targetDuration":4,"studyType":49,"phases":139,"briefSummary":140,"conditions":141,"keywords":142,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":154,"lastUpdatePostDateStruct":155,"startDateStruct":156,"completionDateStruct":158,"leadSponsor":160,"locationsCount":40},"100640239","evaluation-of-a-mobile-health-intervention-to-improve-sexual-and-reproductive-health-outcomes-among-kenyan-adolescents-living-in-urban-informal-settlements-100640239","NCT07587281","Evaluation of a Mobile Health Intervention to Improve Sexual and Reproductive Health Outcomes Among Kenyan Adolescents Living in Urban Informal Settlements","Adolescent participants\n\nInclusion criteria:\n\n* age 15-19\n* residing in one of the informal settlements participating in the study\n* not planning to relocate for 18 months\n* not currently married or living as married\n* comprehension of informed consent\n* willing to provide assent\u002Fconsent\n\nExclusion criteria:\n\n* Age 14 and younger\n* Age 20 and older\n* Married\u002Fliving as married\n* Planning to relocate within 18 months\n* Not residing in one of the informal settlements participating in the study\n* Unable to comprehend informed consent\n* Unwilling to provide assent\u002Fconsent.","15 Years","19 Years",{"count":138,"type":21},610,[51],"This two-year study evaluates a mobile phone-based comprehensive sexuality education program designed to support adolescent sexual and reproductive health in Kenya, where rates of teenage pregnancy and sexually transmitted infections remain high. The program, called AskDoki, delivers age-appropriate health information through the WhatsApp platform and is supported by trained youth peer leaders known as Digital Champions, who help adolescents access and use the program. Communities participating in the study are assigned either to receive the AskDoki program with Digital Champion support (intervention communities) or to not receive the program (comparison communities). Adolescents in both intervention and comparison communities complete surveys before the program begins and again six months after implementation of the AskDoki program. The surveys assess health knowledge, attitudes, perceptions, and intended behaviors related to sexual and reproductive health. The study compares changes in survey responses over time between intervention and comparison communities to assess the program's effectiveness. It also evaluates how feasible it is to use Digital Champions to support adolescents' engagement with the mobile program and examines the cost-effectiveness of this approach.",[27],[143,144,145,146,147,148,149,150,151,152,153],"Sex Education","Pregnancy in Adolescence","Sexually Transmitted Infections","Adolescent","Software","Prevention","Cell Phone","Sexual Health","Reproductive health","mHealth","Cost Effectiveness","2026-05-12",{"date":120,"type":32},{"date":157,"type":21},"2026-05-22",{"date":159,"type":21},"2027-04-30",{"name":161,"class":39},"Pacific Institute for Research and Evaluation",{"id":163,"slug":164,"hasResults":11,"nctId":165,"briefTitle":166,"officialTitle":167,"acronym":4,"eligibilityCriteria":168,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":169,"targetDuration":4,"studyType":49,"phases":171,"briefSummary":172,"conditions":173,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":175,"lastUpdatePostDateStruct":176,"startDateStruct":178,"completionDateStruct":179,"leadSponsor":181,"locationsCount":4},"100632229","mhealth-intervention-for-improving-vaccination-coverage-in-bangladesh-100632229","NCT07510971","mHealth Intervention for Improving Vaccination Coverage in Bangladesh","Mobile Health Solutions Combined With Behavior Change Approaches to Improve Vaccination Coverage and Timeliness in Bangladesh: a Cluster Randomized Controlled Trial","Inclusion Criteria:\n\n1. You are the infant's caregiver (mother, father, or legal guardian).\n2. The infant is less than 4 weeks (28 days) old at the time of enrollment.\n3. You reside within the jurisdiction of the designated community health center and have no plans to move within the next 12 months.\n4. Depending on your assigned group, you can do one of the following:\n\n   * You can read Bengali SMS messages yourself.\n   * You can receive support from a family member living with you who reads Bengali aloud.\n\n   (Note: For the voice call group, literacy is not an issue.)\n5. You understand the content of this study and have completed the required informed consent form.\n\nExclusion Criteria:\n\n1. Caregivers of children aged 4 weeks or older at the time of enrollment\n2. Children who have received any vaccine other than BCG or polio at birth\n3. The caregiver plans to move out of the study area within the next six months.\n4. The caregiver does not want to receive the vaccination at the intervention health center.\n5. The caregiver (father, mother, or other family member) does not have a phone.",{"count":170,"type":21},7800,[51],"Noncompliance and delay in vaccination have caused millions of preventable deaths worldwide particularly in low-and middle-income countries (LMICs). The main reasons for delay in vaccinations or dropout from vaccination programs are vaccine hesitancy, lack of knowledge, forgetting due date, lack of trust, and religious and social barriers. Recently, various mobile health (mHealth) interventions such as voice call, text message reminders have been implemented in LMICs to improve awareness of vaccine availability and provide timely reminders. However, the implication and impact assessment of mHealth interventions with behavior change message for improving vaccination coverage and timeliness is limited. In this project, a three-armed cluster randomized controlled trial (cRCT) will be conducted to assess the impact and cost-effectiveness of mHealth interventions with behavioral change approach on vaccination coverage and timeliness in Bangladesh. A total of 7800 caregivers of children aged less than 4 weeks will be recruited and randomly allocated equally to each arm: control, voice call, and short message service (SMS) reminders with behavioral change message. The primary outcomes will include coverage of full immunization among children in first year of life, and secondary outcomes will be coverage for each vaccine, timeliness, and infant mortality.",[27,174],"SMS","2026-04-09",{"date":177,"type":32},"2026-04-14",{"date":124,"type":21},{"date":180,"type":21},"2028-12-31",{"name":182,"class":183},"Japan Institute for Health Secutiry","OTHER_GOV",{"id":185,"slug":186,"hasResults":11,"nctId":187,"briefTitle":188,"officialTitle":189,"acronym":190,"eligibilityCriteria":191,"healthyVolunteers":11,"sex":192,"minAge":18,"maxAge":4,"enrollmentInfo":193,"targetDuration":4,"studyType":49,"phases":195,"briefSummary":196,"conditions":197,"keywords":199,"overallStatus":119,"whyStopped":4,"lastUpdateSubmitDate":206,"lastUpdatePostDateStruct":207,"startDateStruct":209,"completionDateStruct":211,"leadSponsor":213,"locationsCount":40},"100594029","smoking-cessation-for-fathers-of-sick-children-100594029","NCT07014124","Smoking Cessation for Fathers of Sick Children","mHealth-based Motivational Counselling Integrate With a Sample of Nicotine Replacement Therapy for Fathers of Sick Children Who Smoke Cigarettes: A Pilot Randomized Controlled Trial","Quit-for-Love","Inclusion criteria for parents：\n\n* Parents (mainly fathers) aged ≥18 years and smoke at least one cigarette (including alternative tobacco products) daily in the past seven days\n* Living with a child aged \\\u003C18 years who attended the clinic or were admitted to the pediatric ward\n* Hong Kong residents able to read and communicate in Cantonese or Putonghua\n* Owned a smartphone and can use an instant messaging app (e.g., WhatsApp, Facebook) Inclusion criteria for children\n* Children aged \\\u003C18 years who attended the clinic or were admitted to the pediatric ward\n* Lives with at least one or more parents who smoke at least one cigarette (including alternative tobacco products) daily in the past seven days\n* Able to provide biochemical samples (e.g. saliva) for purpose of research\n\nExclusion criteria for parents\n\n* Smokers having a history of psychiatric\u002Fpsychological disease or currently on regular psychotropic medications\n* Smokers using smoking cessation medications or other smoking cessation services or projects Exclusion criteria for children\n* Children who already have serious health diseases (e.g.chronic disease, genetic disease)\n* Children who are participating in other clinical trials that may affect the results of this study\n* Children who live in certain environments, such as those living in highly contaminated areas or areas with other potential disease-causing factors","MALE",{"count":194,"type":21},160,[51],"The project aims to develop and examine the feasibility, acceptability, and preliminary effectiveness of a proactive intervention model combined brief advice, nicotine replacement therapy sampling and mHealth-based individual counselling in increasing smoking abstinence for fathers of sick children.",[198,27],"Cigarette Smoking",[200,201,202,203,204,205],"tobacco exposure","sick children","quit smoking","Nicotine replacement therapy","mHealth support","smoking fathers","2025-06-02",{"date":208,"type":32},"2025-06-10",{"date":210,"type":32},"2025-03-18",{"date":212,"type":21},"2026-04-01",{"name":128,"class":39},{"id":215,"slug":216,"hasResults":11,"nctId":217,"briefTitle":218,"officialTitle":219,"acronym":4,"eligibilityCriteria":220,"healthyVolunteers":11,"sex":107,"minAge":18,"maxAge":4,"enrollmentInfo":221,"targetDuration":4,"studyType":49,"phases":222,"briefSummary":223,"conditions":224,"keywords":227,"overallStatus":119,"whyStopped":4,"lastUpdateSubmitDate":232,"lastUpdatePostDateStruct":233,"startDateStruct":235,"completionDateStruct":237,"leadSponsor":239,"locationsCount":240},"100575844","ema-and-mhealth-in-preventing-postpartum-depression-100575844","NCT06777563","EMA and mHealth in Preventing Postpartum Depression","Ecological Momentary Assessment Combined mHealth-based Psychosocial Intervention to Prevent Postpartum Depression in Pregnant Women: a Pilot Randomized Controlled Trial","Inclusion Criteria:\n\n1. Pregnant women who are in their 20 to 28 weeks of gestation,\n2. Receiving regular antenatal care service in Hong Kong,\n3. Had a total score ≥7 in EPDS-10 (suggesting potential distress symptoms),\n4. Able to read and understand Chinese and use an instant messaging app weekly\n\nExclusion Criteria:\n\n1\\) Pregnant women who are undergoing psychiatric\u002Fpsychological treatment.",{"count":48,"type":21},[51],"This proposed study aims to develop and examine the feasibility, acceptability, and preliminary effectiveness of a proactive intervention model that combines brief psychological counselling, Ecological Momentary Assessment (EMA), mHealth-based psychological support, and CBT-guided telephone counselling to prevent postpartum depression (PPD).",[225,226,27],"Postpartum Depression (PPD)","Ecological Momentary Assessment",[228,229,230,231],"postpartum depression","ecological momentary assessment","mHealth-based intervention","pregnant women","2025-01-14",{"date":234,"type":32},"2025-01-16",{"date":236,"type":32},"2024-08-25",{"date":238,"type":21},"2025-08-31",{"name":128,"class":39},2,{"id":242,"slug":243,"hasResults":11,"nctId":244,"briefTitle":245,"officialTitle":246,"acronym":4,"eligibilityCriteria":247,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":248,"enrollmentInfo":249,"targetDuration":4,"studyType":49,"phases":251,"briefSummary":252,"conditions":253,"keywords":259,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":268,"lastUpdatePostDateStruct":269,"startDateStruct":271,"completionDateStruct":273,"leadSponsor":275,"locationsCount":277},"100570792","testing-and-comparing-the-impacts-of-mhealth-based-and-web-based-education-on-oral-cancer-100570792","NCT06711848","Testing and Comparing the Impacts of Mhealth-Based and Web-Based Education on Oral Cancer","A Comparative Analysis of the Effectiveness, Usability, Uptake, and Acceptability of an Educational Website and a Mobile Health Application Prototype in Improving Knowledge on Oral Cancer","Inclusion Criteria:\n\n* being a first-year bachelor degree student of either University of Rwanda (Rwanda), University of Peradeniya (Sri Lanka), Usmanu Danfodiyo University (Nigeria), University of Ibadan (Nigeria), or Saveetha University (India)\n* being within the age range of 18 to 39 years\n* having a personal smartphone\n* willingness to participate in the study\n\nExclusion Criteria:\n\n* being a member of staff or a visitor or a non-first year bachelor degree student of University of Rwanda (Rwanda), University of Peradeniya (Sri Lanka), Usmanu Danfodiyo University (Nigeria), University of Ibadan (Nigeria), or Saveetha University (India)\n* being a student of a tertiary institution not selected for the study\n* being below the age of 18 years or above the age of 39 years.\n* not having a personal smartphone\n* not willing to participate in the study","39 Years",{"count":250,"type":21},75,[51],"Introduction: Oral cancer is a malignant neoplastic disease affecting the lip, oral cavity (mouth) and\u002For the oropharynx. Despite the intense and diverse public health interventions on oral cancer prevention, the global prevalence rates of oral cancer and its major risk factors are still very high. Hence, oral cancer is an issue of serious global health importance.\n\nAim: To test and compare the effectiveness, usability, uptake, and acceptability of an educational website and a mobile health application prototype on oral cancer in improving oral cancer knowledge among university students.\n\nMethods: This study will adopt a randomised control trial design, and it will be conducted among 75 first-year bachelor's degree students from five universities across two continents: University of Rwanda (Rwanda, Africa), Usmanu Danfodiyo University (Nigeria, Africa), University of Peradeniya (Sri Lanka, Asia), University of Ibadan (Nigeria), and Saveetha University (India, Aisa). The study participants will be in three groups (Group 1, Group 2, and Group 3). The participants in Group 1 will be the control group (n = 25 participants; 5 participants from each university); that is the group that will not receive an educational intervention. However, those in Group 2 (n = 25 participants; 5 participants from each university) will receive a web-based educational intervention on oral cancer while those in Group 3 (n = 25 participants; 5 participants from each university) will receive an app-based educational intervention on oral cancer. Pretest survey and posttest survey will be done for all participants. The data collected will be statistically analysed using the Statistical Package for Social Sciences (SPSS) version 28 software. Descriptive statistics will be done for all variables while inferential statistics (analysis of variance) will be done to test for associations between variables of interest.\n\nConclusion: The findings of this study will determine the effectiveness, usability, uptake, and acceptability of the tested digital intervention tools.",[254,255,256,257,258],"Oral Cancer","Health Education, Community","Digital Intervention","MHealth Application","MHealth Intervention",[260,261,262,263,264,265,266,267],"mobile health","application","website","impact","knowledge","oral cancer","public health","intervention","2024-11-28",{"date":270,"type":32},"2024-12-02",{"date":272,"type":21},"2025-01-05",{"date":274,"type":21},"2025-04-30",{"name":276,"class":39},"University of Rwanda",5,{"id":279,"slug":280,"hasResults":11,"nctId":281,"briefTitle":282,"officialTitle":283,"acronym":284,"eligibilityCriteria":285,"healthyVolunteers":16,"sex":107,"minAge":73,"maxAge":286,"enrollmentInfo":287,"targetDuration":4,"studyType":49,"phases":288,"briefSummary":289,"conditions":290,"keywords":294,"overallStatus":119,"whyStopped":4,"lastUpdateSubmitDate":300,"lastUpdatePostDateStruct":301,"startDateStruct":303,"completionDateStruct":305,"leadSponsor":307,"locationsCount":40},"100483093","12--bangladesh-center-for-global-environmental-and-occupational-health--bangladesh-100483093","NCT05570552","1\u002F2- Bangladesh Center for Global Environmental and Occupational Health- Bangladesh","Long Term Effects of Household Air Pollution (HAP) Reduction on Cardio-pulmonary and Immune Function Outcomes - a Household Level Randomized mHealth Intervention Trial","GEOHealth-II","Inclusion Criteria:\n\n* Participants in the previous GEOHEALTH round-I study\n* Aged between 25 and 70 years\n* Live in biomass-using home with traditional stoves\n* Non-smoker and live with non-smokers\n* Exposed to \\\u003C10 µg\u002FL of water arsenic\n\nExclusion Criteria:\n\n* Known to have immune related illness or taking any prescription medication (particularly those that suppress or enhance immune function)\n* Known to have any clinical events of CVD or lung disease, including stroke or coronary heart disease.","70 Years",{"count":20,"type":21},[51],"Almost 3 billion people worldwide, including 89% people in Bangladesh, are exposed to harmful household air pollutants (HAP) emitted from combustion of biomass (wood, agricultural residue, cow dung, etc.) fuel use for cooking. While health risks associated with air-pollution have been reasonably well-studied in developed countries, there is little evidence on health benefits achievable by HAP reduction through clean fuel use, especially in low- and middle-income countries (LMICs). Earlier the investigators showed that Liquid Petroleum Gas (LPG) for 24 months, reduced personal PM2.5 exposure by 58.17 percent which induced novel changes in immune and inflammatory responses in the participants; however cardiopulmonary markers remained relatively stable in post-intervention assessment.\n\nIn this study, the investigators aim to evaluate the effects of mobile phone based (mHealth) Behavioural Change Communication (BCC) intervention on adoption and exclusive use of LPG. The investigators also aimed to observe whether long-term effects of HAP reduction can impact the subclinical measures of cardio-vascular and pulmonary dysfunction and regulate innate and inflammatory immune function among women and children in semi-rural settings in Bangladesh. The investigators will also investigate the influence of exposure to HAP on antibody response to vaccines (adaptive immunity). The BCC intervention will be provided by conducting a large household level randomized controlled trial by educational intervention using mHealth based technology. In addition, the investigators will continue following the cohort and will conduct rigorous and repeated personalized (24 hours) and area (over 5 days) assessments of PM2.5 and black carbon (BC) exposure to examine the long-term effects of HAP reduction on subclinical measures of cardio-pulmonary and immune dysfunction including effect of HAP exposure on antibody response to vaccine.",[291,27,292,293],"Air Pollution","Cardiopulmonary Function","Immune Function",[295,296,297,298,299],"Mobile based Behavioral Change Communication intervention","Household air pollution reduction","Cardiopulmonary function","Immune function","Clean fuel LPG","2024-03-20",{"date":302,"type":32},"2024-03-22",{"date":304,"type":32},"2023-06-20",{"date":306,"type":21},"2027-06",{"name":308,"class":39},"International Centre for Diarrhoeal Disease Research, Bangladesh"]