[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"microbial-keratitis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:microbial-keratitis":23},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,38],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":4,"maxAge":4,"enrollmentInfo":16,"targetDuration":4,"studyType":19,"phases":4,"briefSummary":20,"conditions":21,"keywords":24,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":27,"lastUpdatePostDateStruct":28,"startDateStruct":31,"completionDateStruct":33,"leadSponsor":35,"locationsCount":4},"100617255","pattern-of-microbial-keratitis-in-assiut-university-hospital-100617255",false,"NCT07316244","Pattern of Microbial Keratitis in Assiut University Hospital","Inclusion Criteria:\n\n* All cases presented with Microbial keratitis at cornea clinic , Assiut university hospital during the study period.\n\nExclusion Criteria:\n\n* Non-microbial keratitis including Moorens ulcers, chemical burns, and Shield ulcers.","ALL",{"count":17,"type":18},100,"ESTIMATED","OBSERVATIONAL","The aim of the study is to explore the epidemiology, including risk factors, causative microorganisms, complications and clinical outcomes of microbial keratitis among patients attending cornea clinic at Assiut University Hospital.",[22,23],"Keratitis","Microbial Keratitis",[25],"Mk","NOT_YET_RECRUITING","2025-12-30",{"date":29,"type":30},"2026-01-05","ACTUAL",{"date":32,"type":18},"2026-01",{"date":34,"type":18},"2027-03",{"name":36,"class":37},"Assiut University","OTHER",{"id":39,"slug":40,"hasResults":11,"nctId":41,"briefTitle":42,"officialTitle":43,"acronym":44,"eligibilityCriteria":45,"healthyVolunteers":11,"sex":15,"minAge":46,"maxAge":4,"enrollmentInfo":47,"targetDuration":4,"studyType":19,"phases":4,"briefSummary":49,"conditions":50,"keywords":53,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":70},"100507561","use-of-a-new-method-for-the-microbiological-diagnosis-of-severe-corneal-infection-100507561","NCT05888987","Use of a New Method for the Microbiological Diagnosis of Severe Corneal Infection","Use of a New Rapid Multiplex PCR System for the Microbiological Diagnosis of Severe Infectious Keratitis: Impact on Therapeutic Management (ABCORFILM Study)","ABCORFILM","Inclusion criteria:\n\n* Over 18 years old\n* With social security affiliation\n* Willing to participate this study\n* Hospitalized in our department for severe infectious keratitis\n\nNon-inclusion criteria:\n\n* Any prior (48 hours) or concomitant treatment with local or systemic antibiotherapy at time of corneal scrapping and swabbing\n* Patient not covered by the French Health Insurance\n* Unable to give informed consent","18 Years",{"count":48,"type":18},46,"Microbial keratitis is a severe and often blindness-inducing pathology which represents today the first reason for long-term hospitalization (more than 5 days) in ophthalmology. Its diagnosis is clinical and leads to an immediate hospitalization in the presence of serious criteria (Mackie classification). The entire process of microbiological diagnosis requires several days before etiological confirmation and therefore delays the initiation of targeted therapy.\n\nRecently, new PCR systems allowing the detection of 18 to 27 pathogens in 75 minutes have been developed. Their use could thus be transposed to ophthalmology by adapting the microbiological diagnostic technique to samples currently taken by swabbing the cornea.\n\nThe investigators will compare their diagnosis performance versus conventional methods on patients who suffered for a microbial keratitis with severity criteria.",[51,23,52],"Infectious Keratitis","Corneal Infection",[54,55,56,57,58,59],"Severe infectious keratitis","Infectious keratitis","Microbial keratitis","Corneal infection","FilmArray","Multiplex PCR system","RECRUITING","2024-09-06",{"date":63,"type":30},"2024-09-19",{"date":65,"type":30},"2023-07-07",{"date":67,"type":18},"2027-08-07",{"name":69,"class":37},"CHU de Reims",1]