[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"micronutrient-status\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:micronutrient-status":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,54,87,117],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":34,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":53},"100635631","association-of-seafood-consumption-and-nutritional-status-among-adolescent-girls-100635631",false,"NCT07555197","Association of Seafood Consumption and Nutritional Status Among Adolescent Girls","Association of Seafood Consumption and Nutritional Status Among Adolescent Girls Living in Different Aquatic Ecological Zones in Southwestern Bangladesh","AQUAFOOD","Inclusion Criteria:\n\n* Adolescent girls aged between 12-16 years\n* Residing in the same study area as the 2017 IMMANA study\n* Willing to participate and provide informed consent\n\nExclusion Criteria:\n\n* Any health condition that may affect anthropometric measurements\n* Severe illness that may interfere with physical or biochemical assessments",true,"FEMALE","12 Years","17 Years",{"count":22,"type":23},300,"ESTIMATED","OBSERVATIONAL","This study examines how seafood consumption, social changes, and climate change affect the nutrition and well-being of adolescent girls in south-western Bangladesh. Many adolescent girls face poor nutrition, early marriage, and limited access to adequate diets. Adolescent girls have high nutritional needs due to growth and potential early motherhood. Seafood, including fish, shrimp, and prawns, provides important nutrients such as omega-3 fatty acids, but little is known about how its consumption relates to nutritional status in this population.\n\nThe study will collect new data from adolescent girls in the same area as a 2017 study (IMMANA study), assessing dietary pattern, nutritional status, socioeconomic conditions, and female autonomy. It will also explore how climate change affects household food access and nutrition to provide policies linking food systems and public health.",[27,28,29,30,31,32,33],"Nutritional Status","Omega 3 Fat Status","Micronutrient Status","Fish Consumption","Dietary Pattern","Female Autonomy","Climate Change",[35,36,37,38,39,40],"Adolescent nutrition","Aquaculture","Climate change","Fish consumption","Female autonomy","Nutritional status","NOT_YET_RECRUITING","2026-04-30",{"date":44,"type":45},"2026-05-06","ACTUAL",{"date":47,"type":23},"2026-04-25",{"date":49,"type":23},"2026-12-15",{"name":51,"class":52},"University of Copenhagen","OTHER",1,{"id":55,"slug":56,"hasResults":11,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":15,"eligibilityCriteria":60,"healthyVolunteers":17,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":66,"studyType":24,"phases":4,"briefSummary":67,"conditions":68,"keywords":73,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":81,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":53},"100634596","health-and-nutritional-outcomes-among-young-females-and-children-in-southwest-bangladesh-100634596","NCT07541742","Health and Nutritional Outcomes Among Young Females and Children in Southwest Bangladesh","Health and Nutritional Outcomes Among Young Females and Children in Southwest Bangladesh: A Cohort Study","Inclusion Criteria:\n\n* Young women aged 22-27 years who previously participated in the 2017 study. See study description.\n* If the women has a child age between 6 months to 5 years, the child child is included to be assessed\n\nExclusion Criteria:\n\n* Participants with serious health conditions that may interfere with study procedures or data collection.","ALL","5 Months","27 Years",{"count":65,"type":23},240,"2 Years","This study aims to examine how societal and climate changes influence the nutritional status and fish consumption of young women over a 10 year period in southern Bangladesh, and how these factors affect their children's health. A cohort of 240 adolescents first studied in 2017 will be followed to assess changes in their dietary patterns, nutritional status, climate perceptions and mitigation practices, as well as the nutritional status of their children aged 6 months to 5 years.\n\nThe study in 2017 sampled 60 adolescent girls in each of four rural communities, plus a semi-rural community around a fish processing plant, representing in total 5 communities. Of these 60 X 5 = 300 girls, the current study follows up the individuals in the rural communities representing a cohort of 240.\n\nBangladesh faces high rates of adolescent malnutrition, with many girls married before 18 and suffering from chronic nutrient deficiencies. These issues have long-term impacts on health, productivity, and intergenerational well-being. By linking the fisheries and aquaculture sector, a key to Bangladesh's economy with public health and nutrition, this research aims to guide targeted policies for vulnerable coastal communities.",[27,29,28,69,70,71,72],"Diet Diversity","Markers of Inflammation","Climate Adaptation","Climate Change Awareness",[74,75,76,77,78,79,80],"Aquatic foods","adolescent nutrition","fish intake assessment","dietary biomarkers","climate adaptation","intergenerational nutrition","Bangladesh",{"date":44,"type":45},{"date":83,"type":23},"2026-04-15",{"date":85,"type":23},"2026-12-10",{"name":51,"class":52},{"id":88,"slug":89,"hasResults":11,"nctId":90,"briefTitle":91,"officialTitle":91,"acronym":4,"eligibilityCriteria":92,"healthyVolunteers":11,"sex":61,"minAge":93,"maxAge":94,"enrollmentInfo":95,"targetDuration":4,"studyType":97,"phases":98,"briefSummary":100,"conditions":101,"keywords":102,"overallStatus":106,"whyStopped":4,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":53},"100594576","phase-4-a-randomized-controlled-trial-evaluating-the-impact-of-procedure-specific-bariatric-supplements-on-micronutrient-status-and-vitamin-b6-hypervitaminosis-following-metabolic-and-bariatric-surgery-100594576","NCT07021248","A Randomized Controlled Trial Evaluating the Impact of Procedure-Specific Bariatric Supplements on Micronutrient Status and Vitamin B6 Hypervitaminosis Following Metabolic and Bariatric Surgery","Inclusion Criteria:\n\nEligible participants will be adults:\n\n* Aged 18 to 65 years\n* Undergoing primary metabolic and bariatric surgery (MBS), including sleeve gastrectomy (SG), Roux-en-Y gastric bypass (RYGB), or one anastomosis gastric bypass (OAGB).\n* Patients must meet established surgical indications as defined by the International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO), specifically: a body mass index (BMI) greater than 30 kg\u002Fm² with at least one obesity-related comorbidity (e.g., type 2 diabetes, hypertension, obstructive sleep apnea)\n* or a BMI greater than 35 kg\u002Fm² irrespective of comorbidities.\n* Eligible participants must be capable of providing informed consent, willing to adhere to the prescribed supplement regimen, and able to complete scheduled postoperative follow-up visits for 12 months.\n\nExclusion Criteria:\n\nExclusion criteria include:\n\n* Revision or secondary MBS procedures\n* Known hypersensitivity to vitamin B6 or any component of the supplement formulations\n* Pregnancy or planned pregnancy during the study period\n* Any pre-existing medical condition known to interfere with vitamin B6 metabolism. This includes, but is not limited to, severe hepatic or renal dysfunction, peripheral neuropathy, and the use of medications such as isoniazid, phenytoin, or levodopa. Additional exclusions include chronic gastrointestinal conditions affecting absorption (e.g., inflammatory bowel disease, celiac disease), porphyria, or any other clinical scenario that, in the judgment of the investigators, may compromise compliance or the reliability of follow-up.\n* Patients who are already receiving high-dose vitamin B6 supplementation or have abnormal preoperative B6 levels will be excluded.","18 Years","65 Years",{"count":96,"type":23},249,"INTERVENTIONAL",[99],"PHASE4","Obesity is a complex, multifactorial chronic disease with an escalating global incidence, impacting over 650 million adults worldwide. It is closely linked to a variety of metabolic, cardiovascular, and musculoskeletal diseases, and is a leading contributor to preventable morbidity and mortality. Metabolic and Bariatric Surgery (MBS) stands out as the most effective long-term intervention for obesity, facilitating significant and sustained weight loss while also promoting remission of associated diseases.\n\nHowever, the anatomical and physiological alterations induced by MBS, including gastric restriction, bypass of absorptive surfaces, altered gastrointestinal transit, and reduced gastric acid production, significantly disrupt nutrient absorption and metabolism, placing patients at lifelong risk of micronutrient deficiencies or, conversely, hypervitaminosis resulting from excessive supplementation. Among these, Vitamin B6 imbalance has emerged as a significant yet under-recognized issue in post-MBS patients.\n\nAmong the nutrients affected, vitamin B6 (pyridoxine) presents a unique challenge. Vitamin B6 functions as a coenzyme in amino acid metabolism, neurotransmitter synthesis, and immune regulation. Deficiencies in Vitamin B6 are well-documented and can manifest as glossitis, irritability, and peripheral neuropathy. Notably, B6-related neuropathy may clinically resemble Guillain-Barré syndrome in post-MBS patients. This anxiety surrounding deficiency symptoms often leads to the overconsumption of Vitamin B6, resulting in hypervitaminosis, which can also present with neurological manifestations such as sensory neuropathy and ataxia.\n\nThe risk of hypervitaminosis is further exacerbated by the widespread use of high-dose multivitamin formulations post-surgery, many of which contain vitamin B6 at levels far exceeding the Recommended Dietary Allowance (RDA). For males, the RDA is 1.3 mg daily for those aged 19-50 years, increasing to 1.7 mg for those over 50. For females, the RDA is 1.3 mg for those aged 19-50 and 1.5 mg for those over 50. Yet some commercially available bariatric supplements exceed this level several-fold. Studies by Dogan et al. and Homan et al. emphasize the prevalence of vitamin B6 toxicity in post-MBS populations, largely attributable to inappropriate supplementation practices.",[29],[103,29,104,105],"Procedure-Specific Bariatric Supplements","Vitamin B6 Hypervitaminosis","Metabolic and Bariatric Surgery","RECRUITING","2025-09-10",{"date":109,"type":45},"2025-09-16",{"date":111,"type":45},"2025-06-15",{"date":113,"type":23},"2026-06",{"name":115,"class":116},"General Committee of Teaching Hospitals and Institutes, Egypt","OTHER_GOV",{"id":118,"slug":119,"hasResults":11,"nctId":120,"briefTitle":121,"officialTitle":122,"acronym":123,"eligibilityCriteria":124,"healthyVolunteers":17,"sex":61,"minAge":93,"maxAge":94,"enrollmentInfo":125,"targetDuration":4,"studyType":97,"phases":127,"briefSummary":129,"conditions":130,"keywords":131,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":140,"lastUpdatePostDateStruct":141,"startDateStruct":143,"completionDateStruct":145,"leadSponsor":147,"locationsCount":53},"100586871","bioavailability-of-micronutrients-with-a-special-focus-on-vitamin-k-dependent-on-consumed-diet-100586871","NCT06921018","Bioavailability of Micronutrients With a Special Focus on Vitamin K Dependent on Consumed Diet","Bioavailability of Micronutrients With a Special Focus on Vitamin K - Study Part II: PLANTEKOST","BioMicro","Inclusion Criteria:\n\n* Men and women\n* Between 18 and 65 years old (including both 18 and 65 year olds)\n* Danish-speaking\n* Willingness to consume\u002Fcomply with consumption of study-related intervention products\u002Fdiet\n* Willing to take 10 µg vitamin D3\u002Fday and omit intake of all other (vitamins and mineral) supplements before and during the trial\n* BMI ≤ 30.0 kg\u002Fm2\n* Habitual consumption of meat at dinner minimum 5 times per week. Meat is defined as red meat and poultry, where red meat is consumed at dinner at least 2 out of 5 times per week (fish consumption is not included in the \"5 per week\" meat definition).\n\nExclusion Criteria:\n\n* Daily smokers\u002Fusers of all kinds of nicotine-containing products.\n* Occasional smokers\u002Fuser can be included if they are willing to refrain from all kinds of nicotine-containing products during the trial (from screening to end of trial)\n* Blood donation \\\u003C3 months prior to study-related blood sampling\n* Intensive physical training (\\> 10 hours of strenuous physical activity per week)\n* Participation in other clinical studies at the time of the study\n* Pregnant, lactating or planning to become pregnant within the study period\n* Habitual alcohol intake above current recommendation (\\> 10 alcoholic units\u002Fweek)\n* History of cancer within the past five (5) years except basal cell skin cancer and cervix\n* Diagnosed with chronic inflammation disorders\n* Diagnosed with gastrointestinal diseases\n* Diagnosed with bone related diseases\n* Diagnosed with psychiatric disorder including depression that requires medical treatment\n* Medical treatment of diabetes\n* Medical treatment of cardiovascular related disease\n* Surgical change of the gastrointestinal tract (removal of appendix is allowed)\n* Use of prescription medication that can affect their safety or impact on data\n* Inability, physically or mental, to comply with the procedure required by the study protocol and evaluated by the principal investigator (PI), study manager or clinical responsible",{"count":126,"type":23},20,[128],"NA","Objectives\n\nThe main objectives are:\n\n• Study part II: to investigate the effect of a plant-based diet on micronutrient status compared to an average Danish diet\n\nHypotheses Study part II: it is hypothesised that the status of some micronutrients is lower after intake of a plant-based diet compared to an average Danish diet.\n\nParticipants will:\n\nStudy part II: consume either a vegan diet or an average danish diet with a high meat intake for 4 weeks. The total study period for the participants is estimated to 6 weeks (from screening to paticipants last visit)",[29],[132,133,134,135,136,137,138,139],"Bioavailability","Micronutrients","Vitamin K","vitamin B2","Vitamin B12","zinc","iodine","haemoglobin","2025-04-07",{"date":142,"type":45},"2025-04-10",{"date":144,"type":23},"2025-04-01",{"date":146,"type":23},"2031-06-30",{"name":51,"class":52}]