[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"microvascular-decompression-surgery\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:microvascular-decompression-surgery":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,44,69],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100629805","oliceridine-versus-sufentanil-for-postoperative-nausea-in-cerebellopontine-angle-surgery-100629805",false,"NCT07479446","Oliceridine Versus Sufentanil for Postoperative Nausea in Cerebellopontine Angle Surgery","Comparative Study of Oliceridine Versus Sufentanil for Patient-Controlled Intravenous Analgesia in Improving Postoperative Nausea in Patients Undergoing Cerebellopontine Angle Region Surgery.","Inclusion Criteria:\n\n* Scheduled for elective CPA region surgery with planned PCIA.\n* Age 18-65 years.\n* ASA physical status I-III.\n* Provides written informed consent.\n\nExclusion Criteria:\n\n* Opioid tolerance (taking opioids ≥1 week, equivalent to oral morphine ≥50 mg\u002Fday or oxycodone ≥30 mg\u002Fday).\n* Severe cardiopulmonary, hepatic, renal, vascular, neurological, hematological, gastrointestinal, or endocrine diseases.\n* Postoperative ICU admission with tracheal intubation.\n* BMI ≤18.5 or ≥30 kg\u002Fm².\n* Participation in another clinical trial within 3 months prior to screening.","ALL","18 Years","65 Years",{"count":20,"type":21},174,"ESTIMATED","INTERVENTIONAL",[24],"NA","This single-center, double-blind, randomized controlled trial aims to determine whether oliceridine for patient-controlled intravenous analgesia (PCIA) can significantly reduce the incidence of postoperative nausea, an opioid-related adverse reaction, compared to sufentanil PCIA in patients undergoing cerebellopontine angle (CPA) region surgery. A secondary objective is to compare the postoperative analgesic effects between the two drugs. The study plans to enroll 174 patients (with a calculated sample size of 164 plus 5% for attrition). The primary outcome is the incidence of nausea within 6-48 hours postoperatively. Secondary outcomes include pain scores at rest and during movement within 48 hours, and other exploratory outcomes such as vomiting incidence, time to first flatus\u002Fdefecation, and gastrointestinal function scores.",[27,28,29,30],"PONV","Cerebellopontine Angle Tumor","Microvascular Decompression Surgery","Postoperative Analgesia","RECRUITING","2026-05-20",{"date":34,"type":35},"2026-05-22","ACTUAL",{"date":37,"type":35},"2026-03-25",{"date":39,"type":21},"2027-09-30",{"name":41,"class":42},"Xuanwu Hospital, Beijing","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":50,"targetDuration":4,"studyType":52,"phases":4,"briefSummary":53,"conditions":54,"keywords":57,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":43},"100609589","post-operative-trigeminal-pain-after-microvascular-decompression-for-trigeminal-neuralgia-100609589","NCT07216547","Post-Operative Trigeminal Pain After Microvascular Decompression for Trigeminal Neuralgia","Inclusion Criteria:\n\n* MVD post-operative patients with type I Trigeminal Neuralgia.\n\nExclusion Criteria:\n\n* Atypical (Type II) Facial Pain at presentation, revision surgery.\n* Patients who are unable or unwilling to provide informed consent will be excluded from the study.",{"count":51,"type":21},100,"OBSERVATIONAL","The goal of this observational study is to learn about the long-term effects of microvascular decompression (MVD) in patients with trigeminal neuralgia (TN). The main question it aims to answer is:\n\nDoes undergoing post-operative dental treatment or other orofacial stimulation increase the likelihood of pain relapse after MVD for TN?\n\nParticipants who have previously undergone MVD for TN as part of their standard medical care will be asked to complete surveys over phone call. These surveys will focus on their pain experiences, timing, anxiety attacks and nature of any pain relapses, and whether they have received dental treatments or other orofacial interventions during follow-up.",[55,29,56],"Trigeminal Neuralgia","Post-operative Pain",[58],"post operative relapse","NOT_YET_RECRUITING","2025-10-10",{"date":62,"type":35},"2025-10-14",{"date":64,"type":21},"2025-12-12",{"date":66,"type":21},"2026-06-01",{"name":68,"class":42},"Rutgers, The State University of New Jersey",{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":73,"acronym":74,"eligibilityCriteria":75,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":76,"targetDuration":4,"studyType":22,"phases":78,"briefSummary":79,"conditions":80,"keywords":82,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":43},"100443182","assessment-in-patients-with-essential-trigeminal-neuralgia-of-nerve-involvement-by-mri-in-dti-and-functional-connectivity-in-resting-state-100443182","NCT05051072","Assessment in Patients With Essential Trigeminal Neuralgia of Nerve Involvement by MRI in DTI and Functional Connectivity in \"Resting State\"","SENSE","Inclusion Criteria:\n\n* Adult patients (18 years and over);\n* Supported in the neurosurgery department or at the assessment and treatment center for pain for unilateral essential trigeminal neuralgia with search for vasculo-nervous conflict;\n\nExclusion Criteria:\n\n* Patient with neurodegenerative or inflammatory neurological pathology;\n* Patient who has already been operated on for a DMV;\n* Absolute contraindication to MRI\n* Patient benefiting from a legal protection measure; with impaired judgment skills or unable to receive information;\n* Pregnant or breastfeeding women",{"count":77,"type":21},60,[24],"Essential trigeminal neuralgia is the most common facial pain. In forms resistant to drug and disabling treatments, surgical treatment may be offered to the patient. The type of intervention will be conditioned by the presence or absence of a vasculo-nervous conflict objectified by MRI(Magnetic resonance imaging) Morphological MRI with contrast injection does not always allow an accurate assessment of trigeminal nerve damage in patients with essential facial neuralgia. Despite advances in the anatomical definition of high-resolution MRI, the correlation between a vascular conflict visible on MRI and present during surgery and prolonged postoperative clinical improvement remains insufficient These data raise the question of additional imaging sequences to assess the distressing characteristics of NT in addition to the usual anatomical criteria for compression By performing during morphological MRI two additional sequences, one in diffusion tensor (DTI) and one in resting state (fMRI), we could better characterize the achievement of NT\n\nThe contribution of new imaging sequences in the context of essential trigeminal neuralgia treated with microvascular decompression (MVD) would:\n\n1\u002Fimprove the diagnostic criteria for suffering and compression of the NT (trigeminal nerve) 2 \u002F define objective prognostic criteria for the effectiveness of surgery, particularly in the context of unusual clinical symptoms or moderate conflict on MRI (Magnetic resonance imaging) 3 \u002F to analyze more precisely the causes of recurrence at a distance from surgery and help in the decision of re-intervention Our main hypothesis: the addition of a diffusion tensor sequence and sequences (allowing functional brain analysis) in addition to standard anatomical MRI in the assessment of a vasculo-nervous conflict would allow us to better characterize involvement of the trigeminal nerve in essential facial neuralgia. It also helps guide therapeutic management and surgical indications.\n\nThis is a prospective, monocentric cohort study. It will be offered to patients referred to neurosurgery or to the pain assessment and treatment center for assessment and management of a neuralgia of the essential trijumeau unilateral.",[55,29,81],"Diffusion Tensor Imaging",[83],"Resting state","2025-06-06",{"date":86,"type":35},"2025-06-11",{"date":88,"type":35},"2022-04-27",{"date":90,"type":21},"2027-06",{"name":92,"class":93},"Fondation Ophtalmologique Adolphe de Rothschild","NETWORK"]