[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"mild-obstructive-sleep-apnea\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:mild-obstructive-sleep-apnea":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,47],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100561215","phase-2-study-to-examine-the-effect-of-silicone-mouth-tape-on-snoring-and-mild-sleep-apnea-100561215",false,"NCT06587256","Study to Examine the Effect of Silicone Mouth Tape on Snoring and Mild Sleep Apnea.","Mouth Tape for Snoring and Sleep Apnea (MTASSA)","MTASSA","Inclusion Criteria:\n\n* Adult patients with a body mass index of 35 kg\u002Fm2 with a self-reported history of snoring and a bed partner who can provider answers to about the patients snoring. Patients must have a prior sleep study that shows no sleep apnea, or mild sleep apnea (AHI under 15 events\u002Fhr).\n\nExclusion Criteria:\n\n* Allergy to silicone mouth tape, chronic lung disease, facial hair preventing wearing of the tape\n* Grade 3+ or 4+ tonsils, prior palatal or tongue surgery.\n* Patients may not have any form of chronic or acute hypoventilation.\n* Patients must be able to tolerate breathing through their nose with the mouth tape in place for at least 3 minutes.\n* Patients may not be pregnant","ALL","18 Years","75 Years",{"count":21,"type":22},100,"ESTIMATED","INTERVENTIONAL",[25],"PHASE2","Snoring is a common problem caused by vibration of tissues in the throat region during sleep. Although snoring is sometimes dismissed as a minor nuisance rather than a medical disorder, several studies indicate that snoring can disrupt sleep quality of the snorer, as well as the snorer's bed partner. Snoring also might lead to problems such as dry mouth, bad breath, dental problems, and even cardiovascular disease. Current treatments for snoring include lifestyle modifications such as weight loss, side-sleeping, and avoidance of evening alcohol intake. In some cases, invasive surgeries, dental devices, or even CPAP are recommended for snoring. These interventions have mixed effectiveness and may be difficult to use.\n\nIt may be possible to treat snoring by fostering nasal breathing, while avoiding mouth-breathing during sleep. Breathing through the mouth reduces the airway diameter and contributes to snoring. Several studies show that nasal breathing can reduce snoring volume and improve airflow. Recent studies have shown that covering the mouth during sleep with adhesive patches or tape can improve snoring volume without adverse effects. However, these studies were performed in a small number of patients and did not fully measure the impact of the intervention on sleep quality, sleep architecture, or the experience of the bed partner, who is often the overlooked \"victim\" of the snoring. In this interventional study, the investigators will examine the safety and efficacy of mouth tape for snoring, focusing on subjective and objective snoring\u002Fbreathing metrics of both the snorer and bed partner.\n\nSnoring is sometimes also a sign of obstructive sleep apnea (OSA). If OSA is ruled out with a sleep study, patients are considered to have \"simple\" snoring. When OSA is mild (apnea hypopnea index 15), treatments can include the same interventions as snoring (e.g. weight loss, avoidance of alcohol, side-sleeping) or can be more aggressively treated with devices such as continuous positive airway pressure (CPAP). CPAP may be challenging to use, expensive, and associated with side effects such as mouth dryness and skin irritation. Alternative, inexpensive, and well-tolerated interventions are needed for mild OSA. For this reason, the investigators include patients with snoring and mild OSA in this study.",[28,29],"Mild Obstructive Sleep Apnea","Snoring",[31,32,33],"sleep apnea","snoring","mouth tape","RECRUITING","2026-06-18",{"date":37,"type":38},"2026-06-23","ACTUAL",{"date":40,"type":22},"2027-03-01",{"date":42,"type":22},"2030-10",{"name":44,"class":45},"Johns Hopkins University","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":23,"phases":55,"briefSummary":57,"conditions":58,"keywords":59,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":46},"100630803","medcline-investigational-study-for-the-treatment-of-mild-osa-with-positional-therapy-100630803","NCT07492420","MedCline Investigational Study for the Treatment of Mild OSA With Positional Therapy","Inclusion Criteria:\n\n1. Diagnosis with mild obstructive sleep apnea (AHI 5-14.9)\n2. PSG or HST performed within last 24 months\n3. Individuals aged 18 or older\n4. Must routinely sleep on a standard mattress and must be able to accommodate the width of the MedCline Sleep System (30\")\n5. Must be in overall good health, with no significant medical conditions that would interfere with the study procedures or the ability to sleep safely using the MedCline Sleep System\n6. Ability to provide written informed consent in accordance with IRB principles\n7. Must be stable on any medications for at least 3 months prior to the date of consent\n\nExclusion Criteria:\n\n1. Diagnosis of moderate to severe OSA (AHI \\>15) or central sleep apnea\n2. Has undergone surgical procedures for sleep apnea within the last six months\n3. Clinically significant cardiac or respiratory conditions that may interfere with the study intervention or outcomes.\n4. Chronic pain or musculoskeletal disorders, e.g., spinal deformities, scoliosis, kyphosis, back injuries, spinal compressions, or injuries that may affect their ability to sleep comfortably in a lateral position\n5. Pregnant or planning to become pregnant during study period\n6. Any conditions or circumstances that require frequent night-time awakenings (e.g., nocturia, caregiving responsibilities, or other health issues)\n7. Unable or unwilling to use the MedCline Sleep System as required by the study protocol\n8. Currently using substances or medications known to significantly alter sleep architecture or respiratory function (e.g., sedatives, narcotics, or alcohol dependency)",{"count":54,"type":22},35,[56],"NA","The purpose of this study is to evaluate the safety and effectiveness of the MedCline Sleep System in reducing symptoms related to mild OSA.",[28],[60,61,62,63],"mild OSA","positional therapy","supine avoidance","lateral sleeping","2026-03-24",{"date":66,"type":38},"2026-03-27",{"date":68,"type":22},"2026-03-01",{"date":70,"type":22},"2026-10-01",{"name":72,"class":73},"Amenity Health, Inc.","INDUSTRY"]