[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"mixed-pain-nociceptive-and-neuropathic\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:mixed-pain-nociceptive-and-neuropathic":46},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":4},"100562129","phase-1-petmri-for-chronic-pain-from-spinal-or-peripheral-nerve-origin-100562129",false,"NCT06599151","PETMRI for Chronic Pain from Spinal or Peripheral Nerve Origin","Use of (18F)FTC-146 PET_MRI for Characterizing Chronic Pain Phenotypes in Chronic Pain Patients with Spinal or Peripheral Nerve Origin","Inclusion Criteria:\n\n* Healthy Volunteers\n\n  1\\. At least 18 years old.\n* Pain Subjects\n\n  1. At least 18 years old.\n  2. Chronic Pain is of Spinal or Peripheral Nerve Origin\n  3. Subject's Chronic pain lasting greater than 2 months.\n  4. Pain level of at least 4\u002F10 on a 0-10 Comparative Pain Scale.\n\nExclusion Criteria:\n\n* Healthy Volunteers\n\n  1. Any chronic Pain\n  2. Use of pain medication.\n  3. MRI incompatibility.\n  4. Kidney problems.\n  5. Pregnant or nursing.\n  6. Non-English speaker.\n  7. Presence of vasculopathy or Raynaud's.\n  8. Inability to tolerate cessation of anticoagulant medication during the study.\n* Pain Subjects\n\n  1. MRI incompatibility.\n  2. Kidney problems.\n  3. Pregnant or nursing.\n  4. Non-English speaker.",true,"ALL","18 Years",{"count":20,"type":21},200,"ESTIMATED","INTERVENTIONAL",[24],"PHASE1","The purpose of this study is to compare the uptake of \\[18F\\]FTC-146 in healthy volunteers to that of individuals suffering from chronic pain with Spinal or Peripheral Nerve Origin.\n\nPrimary Objectives:\n\nA) To quantify the bio-distribution of \\[18F\\] FTC-146 uptake in subjects with Spinal or Peripheral Nerve Origin pain and compare it with healthy controls.\n\nB) To determine whether painful schwannomas can be differentiated from non-painful schwannomas based on imaging.\n\nSecondary Objectives:\n\nA) To assess the reproducibility of \\[18F\\]FTC-146 PET imaging within the same healthy volunteer subjects using Test-Retest analysis.\n\nB) To investigate whether post-treatment \\[18F\\]FTC-146 uptake differs from pre-treatment uptake and correlate the imaging with subject reported pain level after treatment",[27,28,29,30],"Nerve Pain","Neuropathic Pain","Nociceptive Pain","MIxed Pain (Nociceptive and Neuropathic)",[32,33,27],"PET\u002FMRI","Chronic Pain","NOT_YET_RECRUITING","2024-09-12",{"date":37,"type":38},"2024-09-19","ACTUAL",{"date":40,"type":21},"2024-10-01",{"date":42,"type":21},"2030-10-01",{"name":44,"class":45},"Stanford University","OTHER","Mixed Pain (Nociceptive and Neuropathic)"]