[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"mobility\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:mobility":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,47,77,109,160],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100638592","combined-effect-of-prenatal-stretching-and-kinesiotaping-in-pregnant-women-with-low-back-pain-100638592",false,"NCT07579039","Combined Effect of Prenatal Stretching and Kinesiotaping in Pregnant Women With Low Back Pain","Combined Effect of Prenatal Stretching and Kinesiotaping on Pain, Mobility and Quality of Life in Pregnant Women With Low Back Pain","Inclusion Criteria:\n\n* Pregnant women with clinically diagnosed low back pain\n* Maternal age between 18-35 years.\n* Gestational age between 20-34 weeks\n\nExclusion Criteria:\n\n* High-risk pregnancy\n* Skin allergies (contraindicating kinesiotaping)\n* Previous spinal surgeries","FEMALE","18 Years","35 Years",{"count":20,"type":21},34,"ESTIMATED","INTERVENTIONAL",[24],"NA","Low back pain (LBP) is a prevalent complaint during pregnancy, affecting 50-70% of women, especially in the second and third trimesters. Physiological and biomechanical changes such as hormonal relaxation of ligaments, postural shifts, and increased lumbar lordosis contribute to this condition. LBP during pregnancy can significantly limit mobility, reduce daily activity levels, and impair the quality of life. Conservative interventions like prenatal stretching and kinesiotaping are commonly used by physiotherapists. Stretching improves flexibility and reduces musculoskeletal stress, while kinesiotaping offers support, reduces pain perception, and promotes better posture. However, there is limited clinical evidence evaluating their combined effect in pregnant women with LBP.\n\nThis study will be randomized controlled trial and will be conducted at Rahim Yar Khan hospital and Hamdani Hospital Rahim Yar khan .Non-probability convenience sampling technique will be used. Inclusion criteria include Gestational age 20 -34 weeks with low back pain and age between 18-35 years .Baseline measurement include pain (measured by using 10 cm Numeric Pain rating scale ) mobility (measured by Schober Test) quality of life( SF36 questionaire). Participant will be randomly assigned to either Group A (stretching exercise and kinesiotaping) and Group B (Stretching exercise ). The total duration of the study will be 6 to 8 weeks. After identifying eligible pregnant women, obtaining informed consent, and recording baseline measurements from both groups intervention period will begin, during which participants will receive prenatal stretching and kinesiotaping. After data collection all data analysis will be performed using SPSS version 21.",[27,28,29],"Pain","Mobility","Quality of Life",[31,32,33],"kinesiotaping","prenatal stretching","low back pain","RECRUITING","2026-05-05",{"date":37,"type":38},"2026-05-11","ACTUAL",{"date":40,"type":38},"2025-08-31",{"date":42,"type":21},"2026-09-30",{"name":44,"class":45},"Riphah International University","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":55,"minAge":56,"maxAge":4,"enrollmentInfo":57,"targetDuration":4,"studyType":22,"phases":59,"briefSummary":60,"conditions":61,"keywords":64,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":46},"100575380","brain-stimulation-for-foot-sole-sensation-in-older-adults-with-foot-sole-somatosensory-deficits-100575380","NCT06771531","Brain Stimulation for Foot-sole Sensation in Older Adults With Foot-sole Somatosensory Deficits","Cortical Mechanisms and Modulation of Somatosensation in Older Adults With Foot Sole Somatosensory Impairments","BSFS","Inclusion Criteria:\n\n1. Aged ≥65 years.\n2. Self-reported feeling of unsteadiness or difficulty when standing and walking.\n3. Mild-to-moderate foot-sole somatosensory impairment: the ability to perceive 75g monofilament but inability to perceive 10g monofilament.\n\nExclusion Criteria:\n\n1. self-reported inability to stand or walk continuously for one minute without personal assistance (canes or walkers allowed);\n2. history or presence of foot ulceration, amputation, or deformities;\n3. self-reported uncontrolled pain or pain that is associated with mobility disability;\n4. uncontrolled diabetes mellitus;\n5. hospitalization within the past three months due to acute illness, or as the result of a musculoskeletal injury significantly affecting balance;\n6. persistent severe pain of lower extremity when standing or walking;\n7. diagnosis of dementia, Parkinson's disease, or stroke that affects balance;\n8. unstable medical condition;\n9. legal blindness or deafness;\n10. uncontrolled hypertension (i.e., systolic BP \\>180, diastolic BP \\>100 mm Hg, or prescription of ≥3 anti-hypertensive medications);\n11. functionally limiting nephropathy, severe diseases or transplant of the kidney or liver, renal or congestive heart failure;\n12. active cancer treatment;\n13. balance disorders due to past use of chemotherapy or history of Guillain-Barré syndrome;\n14. use of neuro-active or recreational drugs (e.g., sedatives, anti-psychotics), or alcohol abuse, which may affect the brain excitability;\n15. contraindications to MRI or tDCS (e.g., personal or family history of seizures or epilepsy, metallic or electric bio-implants, claustrophobia, brain surgery);\n16. persistent vertigo;\n17. history of Charcot-Marie-Tooth nerve disease.","ALL","65 Years",{"count":58,"type":21},20,[24],"In older adults, diminished sensation of the legs and feet is highly prevalent and causes poor balance and reduced mobility. This type of sensation is not only dependent upon the receptors and nerves in the legs and feet, but also upon a complex central nervous system pathway that includes the cerebral cortex of the brain. This project will use a form of noninvasive brain stimulation called transcranial direct current stimulation (tDCS) to test whether increasing the excitability of the brain networks that process sensory feedback can augment foot sole sensation, balance, and mobility in older adults suffering from mild-to-moderate foot sole sensory impairments.",[62,63,28],"Somatosensory Function","Balance Control",[65,66,67],"brain stimulation","balance and mobility","foot-sole somatosensory function","2026-04-21",{"date":70,"type":38},"2026-04-22",{"date":72,"type":38},"2026-02-26",{"date":74,"type":21},"2026-12-31",{"name":76,"class":45},"Hebrew SeniorLife",{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":4,"eligibilityCriteria":83,"healthyVolunteers":11,"sex":55,"minAge":84,"maxAge":85,"enrollmentInfo":86,"targetDuration":88,"studyType":89,"phases":4,"briefSummary":90,"conditions":91,"keywords":94,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":46},"100600929","parathyroidectomy-and-mobility-study-100600929","NCT07103876","Parathyroidectomy and Mobility Study","Rescuing Mobility Function Through Surgical Removal of the Parathyroid Gland","Inclusion:\n\n* Age ≥ 60 years;\n* Biochemical diagnosis of hypercalcemic (corrected serum calcium \\>10.2 mg\u002FdL or ionized serum calcium \\>1.31 mmol\u002FdL or 5.2 mg\u002FdL on at least one serum sample) primary hyperparathyroidism as determined by board-certified endocrinologist or endocrine surgeon;\n* Undergoing parathyroidectomy at UF Health;\n* Willing and able to give informed consent.\n\nExclusion:\n\n* Failure to provide informed consent;\n* Biochemical diagnosis of eucalcemic primary hyperparathyroidism (corrected serum calcium ≤10.2 mg\u002FdL or ionized serum calcium ≤1.31 mmol\u002FdL or 5.2 mg\u002FdL on at least one serum sample);\n* Elected not to undergo parathyroidectomy at UF Health;\n* Major surgery as deemed by principal investigator or hip\u002Fknee replacement in the past 6 months;\n* Fractures to the hands, arms or legs within the last 6 months;\n* Traumatic accident (i.e. motor vehicle collision, fall from elevation, etc.) resulting in orthopedic trauma or requiring prolonged immobilization (\\>2 weeks) within the last 6 months;\n* Blood transfusion within the past 3 months;\n* Self-reported myocardial infarction, cerebrovascular accident, or unstable angina within the past 6 months;\n* NYHA Class 3 or 4 congestive heart failure;\n* Major psychiatric disorder;\n* Cancer requiring treatment in the past 1 year (including metastatic cancer), except for locally treated non-melanoma skin cancers or cancers that have clearly been cured or in the opinion of the investigator carry an excellent prognosis (e.g., Stage 1 cervical cancer);\n* Renal failure requiring hemodialysis or peritoneal dialysis\n* Use of bone-modifying therapies (alendronate \\[Fosamax\\], zoledronic acid \\[Reclast\\], denosumab \\[Prolia or Xgeva\\], or romosozumab \\[Evenity\\]) within 1 month of planned surgery\n* Planning to permanently leave the area within 3 months of parathyroidectomy;\n* Vision or hearing impairment - defined as unable to read or listen\u002Ffollow instructions despite the use of maximal assistive devices (i.e. contact lenses, glasses, hearing aids, etc.)\n* Participating in another clinical trial or has received an investigational product within 30 days prior to screening\u002Fenrollment.","60 Years","100 Years",{"count":87,"type":21},80,"6 Months","OBSERVATIONAL","This study evaluates whether surgical removal of the parathyroid gland (parathyroidectomy) improves physical function and mobility in older adults with primary hyperparathyroidism (PHPT). PHPT, a common endocrine disorder in older adults, is associated with reduced muscle strength, mobility, and quality of life. This prospective observational study will enroll up to 80 participants aged 60 and older undergoing parathyroidectomy at UF Health. Participants will complete physical performance tests, wear an Actigraph device to assess physical activity, and provide blood samples for biomarker analysis at pre- and post-operative time points. The goal is to characterize changes in physical function and activity following surgery and to identify biomarkers that may predict mobility improvements. Findings will help inform future larger-scale studies and could expand surgical indications for PHPT in older adults.",[92,93,28],"Hyperparathyroidism","Parathyroid",[95,96,97,98,99],"Physical Function","Inflammatory Biomarkers","Parathyroidectomy","Aging","Physical activity","2025-09-23",{"date":102,"type":38},"2025-09-29",{"date":104,"type":38},"2025-08-15",{"date":106,"type":21},"2027-03-31",{"name":108,"class":45},"University of Florida",{"id":110,"slug":111,"hasResults":11,"nctId":112,"briefTitle":113,"officialTitle":114,"acronym":115,"eligibilityCriteria":116,"healthyVolunteers":11,"sex":55,"minAge":17,"maxAge":4,"enrollmentInfo":117,"targetDuration":4,"studyType":22,"phases":119,"briefSummary":121,"conditions":122,"keywords":133,"overallStatus":151,"whyStopped":4,"lastUpdateSubmitDate":152,"lastUpdatePostDateStruct":153,"startDateStruct":155,"completionDateStruct":157,"leadSponsor":158,"locationsCount":46},"100587065","phase-4-intravenous-acetaminophen-to-reduce-post-operative-opioid-consumption-100587065","NCT06923540","Intravenous Acetaminophen to Reduce Post-operative Opioid Consumption","Evaluating the Impact of IV Acetaminophen on Opioid Consumption in the Postoperative Period in Patients Undergoing Abdominal Surgery","ACETAPOP","Inclusion Criteria:\n\n* Age 18 years or older.\n* Underwent abdominal surgery\n* Underwent elective surgery.\n* Hospitalized in the digestive surgery, hepatobiliary and pancreatic surgery, or gynecology and gynecologic oncology units at CHUM.\n* Declared NPO immediately post-surgery, meaning they cannot take oral medications.\n\nExclusion Criteria:\n\n* Hypersensitivity to acetaminophen or an excipient in the administered formulations\n* Hepatic insufficiency with a Child-Turcotte-Pugh score of B or C.\n* Weight \\\u003C 50 kg (patients requiring a lower acetaminophen dose).\n* Active pregnancy or breastfeeding.\n* Opioid use disorder (OUD) under active treatment\n* Non-opioid-naïve patients: those who received a long-acting opioid within seven days preceding surgery. This criterion will be verified through patient interviews and cross-checked with medical records.\n* Use of illicit recreational substances.\n* Prior participation in this study.\n* Ectopic patients: physically located in a unit other than digestive surgery (11 South), hepatobiliary and pancreatic surgery (14 South), or gynecology and gynecologic oncology (12 South).",{"count":118,"type":21},140,[120],"PHASE4","Acetaminophen (Tylenol) is a commonly used medication after surgery to control pain. Tablets for oral use and suppositories for rectal use are the most frequently employed forms of acetaminophen after surgery. Intravenous (IV) acetaminophen is widely used in several countries but is not a standard medication for the adult population in Canada. It is mainly considered when it is impossible to take medication in tablet or suppository form. Opioids (Morphine, Hydromorphone, Oxycodone, etc.) are another class of medications commonly used after surgery for pain management. While they are generally very effective and stronger than acetaminophen or other pain relievers (e.g., ibuprofen\u002FAdvil), reducing their use is preferable, as they can cause various side effects such as nausea, dizziness, and dependence. IV acetaminophen may help control pain while also reducing opioid consumption. However, there are few high-quality scientific studies proving the benefits of IV acetaminophen compared to other forms, such as tablets or suppositories. Acetaminophen has been available in Canada for many years and has already been recommended for use in Quebec by the Institut national d'excellence en santé et services sociaux (INESSS) under certain conditions. This study aims to validate its benefits with clear data.",[123,124,125,126,127,128,129,28,130,131,132],"Post Operative Analgesia","Opioid Consumption, Postoperative","Acetaminophen","Abdominal Surgeries","Post Operative Bowel Dysfunction","Post Operative Nausea and Vomiting","Post Operative Pain Control","Epidural Analgesia","Length of Stay","Pain Management",[134,135,136,137,138,139,140,141,142,143,144,145,146,147,148,149,150],"IV acetaminophen","intravenous acetaminophen","acetaminophen","post operative analgesia","nil per os","npo","post operative pain","opioid consumption","abdominal surgery","hepato-biliary surgery","digestive surgery","pancreatic surgery","gynecologic surgery","post operative nausea and vomiting","post operative mobility","hospitalization length of stay","co-analgesia","NOT_YET_RECRUITING","2025-04-04",{"date":154,"type":38},"2025-04-11",{"date":156,"type":21},"2025-04-28",{"date":104,"type":21},{"name":159,"class":45},"Centre hospitalier de l'Université de Montréal (CHUM)",{"id":161,"slug":162,"hasResults":11,"nctId":163,"briefTitle":164,"officialTitle":165,"acronym":166,"eligibilityCriteria":167,"healthyVolunteers":11,"sex":16,"minAge":168,"maxAge":18,"enrollmentInfo":169,"targetDuration":4,"studyType":22,"phases":171,"briefSummary":172,"conditions":173,"keywords":176,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":181,"lastUpdatePostDateStruct":182,"startDateStruct":184,"completionDateStruct":186,"leadSponsor":188,"locationsCount":46},"100579441","effect-of-targeted-mobilization-program-100579441","NCT06824337","Effect of Targeted Mobilization Program","Effect of Targeted Mobilization Program Applied After Caesarean Section Surgery on Care Outcomes: Randomized Controlled Study","Mobilization","Inclusion Criteria:\n\n* Between the ages of 18-35,\n* At least primary school graduate,\n* Giving birth at term\n* Having a live singleton pregnancy,\n* No risky pregnancy history (DVT, thromboembolism)\n* Women who can use a mobile phone\n\nExclusion Criteria:\n\n* Exclusion Criteria for the Study\n* Those who want to leave the study,\n* Undergoing emergency caesarean section,\n* Not recording walking distance\n* Women who cannot be interviewed within 24 hours of discharge\n* Women who develop maternal or neonatal complications after birth","18 Months",{"count":170,"type":21},64,[24],"This study was planned to evaluate the effect of early mobilization training given to patients undergoing cesarean section in the preoperative period and targeted mobilization program applied after the surgery, on preventing gastrointestinal complications that may develop after the surgical intervention and participating in breastfeeding and baby care. The research will be conducted in experimental design. The research will begin after receiving written permission from Niğde Ömer Halisdemir University Ethics Committee, Niğde Provincial Health Directorate and Ömer Halisdemir Training and Research Hospital. Pregnant women who are between the ages of 18-35, who are at least a primary school graduate, who gave birth at term, who have a live singleton pregnancy, and who do not have a risky pregnancy history (DVT, thromboembolism) will be included in the study. Before starting the research, the study will begin by obtaining institutional permissions and written permission from the pregnant women. Personal Information Form prepared in line with the literature, postoperative gastrointestinal functions information form, postoperative abdominal distension diagnosis form, walking chart, VAS, LATCH Breastfeeding Diagnosis and Evaluation Scale and Breastfeeding Information Form data collection forms will be used to collect data. The data will be evaluated on a computer using the IBM SPSS Statistics 24 (Statistical Package for the Social Sciences for Windows) package program. Appropriate statistical analyzes will be used to evaluate the data",[174,28,27,175],"Caesarean Section","Breastfeeding",[177,178,179,180],"Caesarean section","mobilization","pain","breastfeeding","2025-02-12",{"date":183,"type":38},"2025-02-13",{"date":185,"type":38},"2024-12-01",{"date":187,"type":21},"2025-04-01",{"name":189,"class":45},"Nigde Omer Halisdemir University"]