[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"moderate-acute-malnutrition-mam\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:moderate-acute-malnutrition-mam":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,50],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":32,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100639597","effectiveness-of-positive-deviancehearth-in-treating-uncomplicated-moderate-acute-malnutrition-in-children-6-59-months-in-mymensingh-division-bangladesh-100639597",false,"NCT07591064","Effectiveness of Positive Deviance\u002FHearth in Treating Uncomplicated Moderate Acute Malnutrition in Children 6-59 Months in Mymensingh Division, Bangladesh","The Effectiveness of Positive Deviance\u002FHearth (PDH), a Local Dietary Approach, to Treat Uncomplicated Moderate Acute Malnutrition (MAM) in Children 6-59 Months in Mymensingh, Bangladesh","PD\u002FHearth MAM","Inclusion Criteria:\n\n* Children 6-52.9 months at Baseline. This is so that children are 6-59 months by end of study (6-7 months from baseline)\n* Children with MAM (WHZ\u002FWLZ \\\u003C-2 and ≥-3 and\u002For MUAC \\\u003C125mm and ≥115mm)\n* No Medical Complications (passes IMCI screening questions)\n* No oedema\n* Child does not deteriorate to SAM (WHZ\u002FWLZ\\\u003C-3 and\u002For MUAC\\\u003C115mm) because child should be referred to health centre\n* Caregiver refuses to receive age-appropriate immunization, Vitamin A and deworming minimum 2 weeks before PDH begins\n* Child is not planning to live outside the study area routinely for more than 2 weeks during the 3 months of the study\n* Written\u002FOral consent is given by Parent\u002FCaregiver to participate in the study\n\nExclusion Criteria:\n\n* Child is not between 6-52 months of age at Baseline\n* Child does not meet the inclusion criteria for WHZ\u002FWLZ and\u002For MUAC; (WHZ\u002FWLZ \\\u003C-2SD and ≥-3SD and\u002For MUAC \\\u003C125mm and ≥115mm);\n* Child has oedema;\n* Child has medical complications and\u002For does not pass the IMCI screening including fever, nausea\u002Fvomiting, acute respiratory illness (refer to Study Protocol V2.0, 19 Feb 2026);\n* Deteriorates to SAM and must be removed from the study and referred to the health centre for specially formulated food (SFF) treatment;\n* Refuses to receive minimum 2 weeks before the intervention begins, age-appropriate immunization and Vitamin A and deworming in the past 6 months;\n* Child lives outside the study area routinely or will be outside of the study area for more than 2 weeks in the upcoming 3 months\n* Parent\u002FCaregiver unable or unwilling to attend PDH from start;\n* Parent\u002FCaregiver does not provide written or oral consent to screen for the trial;\n* Parent\u002FCaregiver does not provide informed consent for the study; and\n* any other reason.",true,"ALL","6 Months","59 Months",{"count":22,"type":23},400,"ESTIMATED","INTERVENTIONAL",[26],"NA","The goal of this clinical trial (cluster randomized controlled trial) is to learn whether a Positive Deviance\u002FHearth (PDH) intervention can effectively treat moderate acute malnutrition (MAM) and reduce relapse compared to standard care in children aged 6-59 months diagnosed with MAM in Bangladesh. The main questions it aims to answer are:\n\n* Does the PDH intervention improve recovery rates among children with MAM?\n* Does the PDH intervention reduce relapse to MAM or progression to severe acute malnutrition (SAM) after recovery?\n\nResearchers will compare communities receiving the PDH intervention to communities receiving standard nutrition care (e.g., usual counseling or supplementary feeding programs) to see if PDH leads to better nutritional recovery and sustained outcomes.\n\nParticipants will:\n\n* Take part in a 12-day \"Hearth\" nutrition education program where caregivers prepare and feed children nutrient-dense meals using local foods\n* Receive 2 weeks of home follow-up visits by volunteers after the Hearth sessions, along with ongoing growth monitoring and counseling twice per month\n* Undergo periodic anthropometric assessments (weight, height\u002Flength, Mid-upper arm circumference (MUAC)) at key time points",[29,30,31],"Moderate Acute Malnutrition (MAM)","Undernutrition","Wasting",[33,34,35,36],"Moderate acute malnutrition (MAM)","Children","relapse","positive deviance\u002Fhearth","NOT_YET_RECRUITING","2026-05-08",{"date":40,"type":41},"2026-05-15","ACTUAL",{"date":43,"type":23},"2026-05-16",{"date":45,"type":23},"2026-12-17",{"name":47,"class":48},"World Vision US","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":24,"phases":59,"briefSummary":60,"conditions":61,"keywords":63,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":49},"100640887","regular-growth-monitoring-rgm-of-young-children-in-guinea-bissau-100640887","NCT07584395","Regular Growth Monitoring (RGM) of Young Children in Guinea-Bissau","Pilot Study to Assess the Benefits and Sustainability of Regular Growth Monitoring (RGM) of Young Children in Villages in Guinea-Bissau","Inclusion Criteria:\n\n* Children aged 6 months to 5 years residing in one of the two selected villages in Guinea-Bissau\n* Caregiver willing to enroll the child in the study (verbal consent provided)\n* Caregiver can provide birth certificate or documentation of child's age\n* Child does not have severe acute malnutrition (SAM) at the baseline assessment\n\nExclusion Criteria:\n\n* Children diagnosed with severe acute malnutrition (SAM) at baseline (these children will be referred to the local malnutrition clinic)\n* Children whose caregivers do not wish to participate","5 Years",{"count":22,"type":23},[26],"Wasting (severe thinness) is a common and serious problem among young children in rural Guinea-Bissau. Community Health Agents (CHAs) can help prevent malnutrition by regularly measuring children's growth and advising families on nutritious local foods. However, this practice is not consistently implemented.\n\nThis pilot study will test whether implementing Regular Growth Monitoring (RGM) by CHAs every month is feasible and effective in reducing malnutrition among children aged 6 months to 5 years in two rural villages. Investigators will also compare three methods for measuring mid-upper arm circumference (MUAC), which is used to detect malnutrition: the standard WHO tape measure, a photograph of the arm, and a simple bracelet. The goal is to identify which method is easiest for CHAs to use reliably.\n\nBaseline and final measurements will be taken in both villages. One village will receive the monthly RGM intervention first, followed by the second village. Families will also be asked about their experiences with the program through brief questionnaires.",[62,29],"Severe Acute Malnutrition",[64,65,66,31,67],"Childhood malnutrition","Growth monitoring","Guinea-Bissau","Mid-upper arm circumference","2026-05-07",{"date":70,"type":41},"2026-05-13",{"date":72,"type":23},"2026-05-02",{"date":74,"type":23},"2026-12",{"name":76,"class":48},"Trustees of Dartmouth College"]