[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"moderate-pulpitis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:moderate-pulpitis":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100602401","outcome-of-partial-pulpotomy-in-moderate-and-severe-pulpitis-100602401",false,"NCT07123025","Outcome of Partial Pulpotomy in Moderate and Severe Pulpitis","Inclusion Criteria:\n\n1. Patients aged 15-40 years.\n2. Mature permanent mandibular molars with extremely deep caries on radiograph, giving positive response to pulp sensibility test.\n3. For Moderate Pulpitis- strong, heightened and prolonged reaction to cold, which can last for minutes, possibly percussion sensitive and spontaneous dull pain that can be more or less suppressed with pain medication.\n\n   For Severe Pulpitis- Severe spontaneous pain and clear pain reaction to warmth and cold stimuli, often, sharp to dull throbbing pain, patients have trouble sleeping because of the pain (gets worse when lying down). Tooth is very sensitive to touch and percussion.\n4. Pulpal bleeding can be controlled within 10 minutes\n5. Patients having normal periapical status with periapical index (PAI) score ≤ 2\n6. Periodontally healthy teeth\n7. Positive response to pulp sensibility test\n\nExclusion Criteria:\n\n1. Non restorable teeth\n2. Negative response to vitality testing\n3. Presence of sinus tract or soft tissue swelling\n4. Absence of deep carious lesions radiographically\n5. Radiographic signs of internal or external root resorption\n6. Patient had moderate to severe pain, but preferred root canal treatment\n7. Presence of sound dentin over pulp and pulp not exposed intraoperatively\n8. Pulp haemorrhage could not be arrested within 10 minutes.\n9. Necrotic pulp evident upon exposure\n10. Pregnant women\n11. Absence of antagonist teeth",true,"ALL","15 Years","40 Years",{"count":20,"type":21},120,"ESTIMATED","INTERVENTIONAL",[24],"NA","The aim of the study is to compare the outcome of Partial Pulpotomy in mature permanent teeth with moderate and severe pulpitis.\n\nOBJECTIVE: Primary objective- to compare the difference in clinical and radiographic outcome of partial pulpotomy in mature permanent teeth with moderate and severe Pulpitis. Secondary objective- To evaluate and compare OHRQoL and postoperative pain after Partial Pulpotomy in teeth with Moderate Pulpitis and Severe Pulpitis. Subjects of age group 15 to 40 years will be included and divided into two groups\n\n1. Permanent mature molars with Moderate Pulpitis\n2. Permanent mature molars with Severe Pulpitis",[27,28,29],"Moderate Pulpitis","Severe Pulpitis","Extremely Deep Caries",[31],"partial pulpotomy","RECRUITING","2025-08-21",{"date":35,"type":36},"2025-08-28","ACTUAL",{"date":38,"type":36},"2025-04-18",{"date":40,"type":21},"2027-04-18",{"name":42,"class":43},"Postgraduate Institute of Dental Sciences Rohtak","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":15,"sex":16,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":4,"studyType":22,"phases":56,"briefSummary":57,"conditions":58,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":44},"100550490","comparative-evaluation-of-direct-pulp-capping-and-complete-pulpotomy-in-mature-permanent-mandibular-molars-with-clinical-signs-indicative-of-moderate-pulpitis-100550490","NCT06447753","COMPARATIVE EVALUATION OF DIRECT PULP CAPPING AND COMPLETE PULPOTOMY IN MATURE PERMANENT MANDIBULAR MOLARS WITH CLINICAL SIGNS INDICATIVE OF MODERATE PULPITIS","COMPARATIVE EVALUATION OF DIRECT PULP CAPPING AND COMPLETE PULPOTOMY IN MATURE PERMANENT MANDIBULAR MOLARS WITH CLINICAL SIGNS INDICATIVE OF MODERATE PULPITIS: RANDOMIZED CLINICAL TRIAL","Inclusion Criteria:\n\n1\\. The patient should be ≥18 years of age. 2. Restorable mature permanent 1 st and 2nd Mandibular molars with extremely deep caries (≥2\u002F3 dentine involvement) 3. Tooth should give positive response to pulp sensibility testing. 4. Clinical diagnosis of moderate pulpitis. 5. Radiographic finding of periapical index (PAI) score ≤2. 6. Healthy periodontium (probing pocket depth ≤3 mm and mobility within normal limit).\n\n\\-\n\nExclusion Criteria:\n\n1. Teeth with immature roots.\n2. No pulp exposure after caries excavation.\n3. Bleeding could not be controlled in 6 minutes.\n4. Signs of pulpal necrosis, sinus tract, swelling, insufficient bleeding after pulp exposure.\n5. History of analgesic intake in previous 1 week, or antibiotic intake in 1 month.\n6. Internal\u002Fexternal resorption.\n7. Contributory medical history (alcoholism, smokers, diabetic, hypertension, drug dependency, Heart or valve disease, hepatitis, herpes, immunodeficiency (HIV), infectious diseases, kidney or liver, migraine) -","18 Years","60 Years",{"count":55,"type":21},92,[24],"Title: Comparative evaluation of direct pulp capping and complete pulpotomy in mature permanent mandibular molars with clinical signs indicative of moderate pulpitis: Randomized Clinical Trial\n\nRationale: According to new Wolters pulpal clinical classification, Moderate pulpitis exhibit symptoms of prolonged reaction to cold, which can last for minutes, possibly percussion sensitive and spontaneous dull pain which are correspond to irreversible pulpitis.\n\nComplete\u002Fpartial pulpotomy are suggested to be the choice of treatment for such cases. It has been suggested that infection is often the cause of inflammation, an inflamed pulp should be able to heal if the source of infection is eliminated as in other body organs. Removal of trigger (i.e. caries) followed by application of biocompatible material which makes a good seal in a sterile environment has potential to allow for recovery and healing of the inflamed pulp tissue which is thought to be beyond recovery. Based on this premise, DPC can be considered as minimally invasive approach for the management of teeth with inflamed pulps in place of the conventional approach of partial\u002Fcomplete pulpotomy in adults\n\nResearch Question Does Direct Pulp Capping have comparable outcome with complete pulpotomy in mature permanent teeth with clinical signs indicative of moderate pulpitis?",[27],"2024-06-02",{"date":61,"type":36},"2024-06-07",{"date":63,"type":36},"2023-06-01",{"date":65,"type":21},"2024-11-30",{"name":42,"class":43}]