[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"modified-radical-mastectomy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:modified-radical-mastectomy":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,49,75,99,122],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100644620","comparson-of-analgesc-effcacy-of-dfferent-volumes-of-serratus-posterior-superor-intercostal-plane-block-after-modfed-radcal-mastectomy-surgery-100644620",false,"NCT07670078","Comparıson of Analgesıc Effıcacy of Dıfferent Volumes of Serratus Posterior Superıor Intercostal Plane Block After Modıfıed Radıcal Mastectomy Surgery","Comparıson of Analgesıc Effectıveness of Dıfferent Volumes of Serratus Posterıor Superıor Intercostal Plane Block In Patıents Undergoıng Modıfıed Radıcal Mastectomy Surgery","Inclusion Criteria:\n\n* The study included adult patients over 18 years of age who underwent modified radical mastectomy under general anesthesia and were classified in risk groups I-II-III according to the American Society of Anesthesiologists (ASA) risk classification.\n\nExclusion Criteria:\n\n* patients with coagulopathy,\n* patients with signs of infection at the block application site,\n* patients with ASA IV\n* patients with known allergies to any of the study drugs,\n* patients with ineffective block\n* patients who could not cooperate during postoperative pain assessment\n* patients who wanted to withdraw from the study,\n* patients with alcohol and drug addiction,\n* patients with musculoskeletal abnormalities\n* patients with kidney and liver failure\n* patients with obesity (body mass ≥ 35 kg\u002Fm2)","FEMALE","18 Years","65 Years",{"count":20,"type":21},90,"ESTIMATED","INTERVENTIONAL",[24],"NA","The aim of researchers is to compare the effects of three different local anesthetic concentrations and volumes on opioid consumption, postoperative analgesic efficacy, and pain scores during ultrasound-guided SPSIP blocks in patients undergoing modified radical mastectomy. Additionally, we aim to map and identify the dermatomal areas where different concentrations and volumes of SPSIP blocks provide analgesia.",[27,28,29],"Modified Radical Mastectomy","Post Operative Pain, Acute","Facial Plane Blocks",[31,32,33,34,35],"postoperative pain","regional anesthesia","Modified radical mastectomy","opioid free analgesia","facial plan block","NOT_YET_RECRUITING","2026-06-25",{"date":39,"type":40},"2026-06-29","ACTUAL",{"date":42,"type":21},"2026-08-15",{"date":44,"type":21},"2027-08-30",{"name":46,"class":47},"Cumhuriyet University","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":58,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":48},"100641608","subtransverse-interligamentary-block-versus-paravertebral-block-for-quality-of-recovery-after-mastectomy-100641608","NCT07647367","Subtransverse Interligamentary Block Versus Paravertebral Block for Quality of Recovery After Mastectomy","Ultrasound-Guided Subtransverse Interligamentary Plane Block Versus Thoracic Paravertebral Block for Quality of Recovery After Modified Radical Mastectomy: A Randomized Non-Inferiority Trial","Inclusion Criteria:\n\n* Adult female patients aged 18 to 65 years with American Society of Anesthesiologists (ASA) Physical Status I - III, who were scheduled for unilateral MRM surgery under general anesthesia and able to understand and complete the QoR-15 questionnaire\n\nExclusion Criteria:\n\n* • Patients declined to participate in the trial.\n\n  * History of allergy to the used local anesthetic (LA) drugs.\n  * Patients with cutaneous lesions at the needle entry point.\n  * Coagulopathy or current anticoagulant therapy contraindicating regional block.\n  * Patients with severe hepatic, renal, cardiac, or respiratory disease.\n  * Psychiatric or cognitive disorder interfering with QoR-15 assessment\n  * Chronic opioid use or chronic pain syndrome.\n  * Failed block.\n  * Morbid obesity (body mass index \\>40 kg\u002Fm2)\n  * Intraoperative major complications requiring postoperative ICU admission.\n  * Pregnancy",{"count":57,"type":21},60,[24],"This prospective randomized controlled double blinded non-inferiority study will be carried out in Tanta University Hospitals for duration of 6 months from June 2026 to December 2026 on 60 female patients scheduled for unilatral modified radical mastectomy under general anesthesia.",[61,27],"Quality of Recovery (QoR-15)",[63,64,65],"subtransverse interligamentary plane block","modified radical mastectomy","quality of recovery","2026-06-14",{"date":68,"type":40},"2026-06-17",{"date":70,"type":21},"2026-06",{"date":72,"type":21},"2027-01",{"name":74,"class":47},"Tanta University",{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":81,"eligibilityCriteria":82,"healthyVolunteers":11,"sex":16,"minAge":83,"maxAge":84,"enrollmentInfo":85,"targetDuration":4,"studyType":22,"phases":87,"briefSummary":88,"conditions":89,"keywords":4,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":4},"100626330","adding-magnesium-sulfate-to-combined-pecto-intercostal--serratus-anterior-planes-block-on-post-operative-analgesia-in-patients-undergoing-modified-radical-mastectomy-100626330","NCT07434232","Adding Magnesium Sulfate to Combined Pecto-Intercostal & Serratus Anterior Planes Block on Post-operative Analgesia in Patients Undergoing Modified Radical Mastectomy","Efficacy of Adding Magnesium Sulfate to Combined Pecto-Intercostal & Serratus Anterior Planes Block on Post-operative Analgesia in Patients Undergoing Modified Radical Mastectomy: A Prospective, Randomized Controlled Clinical Trial","Mastectomy","Inclusion Criteria:\n\n* Female patients aged 30 to 75 years diagnosed with non-metastatic breast cancer and scheduled for modified radical mastectomy.\n* ASA, I-III and NYHA, I-II.\n* Written informed consent.\n\nExclusion Criteria:\n\n* ASA physical status \\>III and NYHA \\>II,\n* body mass index \\>40 kg\u002Fm2,\n* pregnant women,\n* Patients with organ failure or coagulation disorders.\n* Allergy to local anesthetics or magnesium sulfate\n* Contraindications as local infection\n* History of chronic pain or opioid use .\n* Unwilling to participate in the study","30 Years","75 Years",{"count":86,"type":21},100,[24],"Here, in our study, we intend to compare the analgesic efficacy of magnesium sulfate as an adjuvant to local anesthetics added to the Pecto-Intercostal Fascial Block (PIFB) vs the Serratus Anterior Plane Block (SAPB) in patients undergoing modified radical mastectomy.\n\nStudy Endpoints Primary Endpoints: Total intravenous opioid consumption during the first 24 hours following surgery. Secondary Endpoints: Postoperative analgesia, 24 hours after surgery, assessed using the Visual Analog Scale (VAS) and time to first analgesic request.",[27],"2026-02-22",{"date":92,"type":40},"2026-02-25",{"date":94,"type":21},"2026-02-15",{"date":96,"type":21},"2027-04-15",{"name":98,"class":47},"South Egypt Cancer Institute",{"id":100,"slug":101,"hasResults":11,"nctId":102,"briefTitle":103,"officialTitle":104,"acronym":4,"eligibilityCriteria":105,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":106,"targetDuration":4,"studyType":22,"phases":108,"briefSummary":109,"conditions":110,"keywords":4,"overallStatus":113,"whyStopped":4,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":117,"completionDateStruct":118,"leadSponsor":120,"locationsCount":48},"100621203","costotransverse-foramen-block-with-erector-spinae-plane-block-in-modified-radical-mastectomy-100621203","NCT07367568","Costotransverse Foramen Block With Erector Spinae Plane Block in Modified Radical Mastectomy","Comparison of Costotransverse Foramen Block With Erector Spinae Plane Block in Modified Radical Mastectomy: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Adult females \\> 18 years and ≤ 65 years old.\n* American Society of Anesthesiologists (ASA) physical status П-III.\n* Body mass index (BMI) 18-35 kg\u002Fm2.\n* Scheduled for modified radical mastectomy.\n\nExclusion Criteria:\n\n* Known allergy or hypersensitivity to local anesthetic agents.\n* Active infection at the injection site (e.g., cellulitis, abscess).\n* Coagulopathy or ongoing anticoagulant\u002Fantiplatelet therapy \\[International Normalized Ratio (INR) \\> 1.5 or platelet count \\\u003C 100,000\u002FµL\\].\n* Severe respiratory, cardiac, hepatic, or renal disease.\n* Morbid obesity.\n* Severe cognitive impairment or uncooperative behavior that could interfere with block placement.",{"count":107,"type":21},110,[24],"This study aims to compare the costotransverse foramen block with erector spinae plane block in modified radical mastectomy.",[111,112,27],"Costotransverse Foramen Block","Erector Spinae Plane Block","RECRUITING","2026-01-24",{"date":116,"type":40},"2026-01-27",{"date":114,"type":40},{"date":119,"type":21},"2026-06-01",{"name":121,"class":47},"National Cancer Institute, Egypt",{"id":123,"slug":124,"hasResults":11,"nctId":125,"briefTitle":126,"officialTitle":127,"acronym":128,"eligibilityCriteria":129,"healthyVolunteers":11,"sex":16,"minAge":130,"maxAge":18,"enrollmentInfo":131,"targetDuration":4,"studyType":22,"phases":132,"briefSummary":134,"conditions":135,"keywords":137,"overallStatus":113,"whyStopped":4,"lastUpdateSubmitDate":143,"lastUpdatePostDateStruct":144,"startDateStruct":146,"completionDateStruct":148,"leadSponsor":150,"locationsCount":48},"100588893","phase-3-comparison-between-erector-spinae-plane-block-versus-serratus-anterior-plane-block-regarding-analgesia-post-modified-radical-mastectomy-100588893","NCT06947330","Comparison Between Erector Spinae Plane Block Versus Serratus Anterior Plane Block Regarding Analgesia Post Modified Radical Mastectomy","Comparison Between Ultrasound Guided Erector Spinae Plane Block Versus Ultrasound Guided Serratus Anterior Plane Block Regarding Analgesia Post Modified Radical Mastectomy","FMASUMD66\u002F2025","Inclusion Criteria:\n\n* ASA Physical Status II, or III.\n* Age 21 - 65 years.\n* Female gender\n\nExclusion Criteria:\n\n* ASA IV, V, VI.\n* Infection at site of block.\n* Coagulopathy, or patients on antiplatelets, or anticoagulants.\n* Previous anesthetic allergy to bupivacaine.\n* Distant organ metastasis.\n* Male gender.","21 Years",{"count":86,"type":21},[133],"PHASE3","The goal of this clinical trial is to compare Ultrasound Guided Erector Spinae and Ultrasound Guided Serratus Anterior Plane Block post Modified Radical Mastectomy in adult females. the main questions it aims to answer are:\n\n* Which of the two blocks has a better analgesic effect?\n* Which of the two blocks is safer as regards inducing a pneumothorax and affecting the hemodynamics?\n\nParticipants:\n\n* Will be divided into two groups after signing the informed consent.\n* After being anesthetized and before surgical incision; the blocks will be given to the patient.\n* Lung Ultrasound will be done for each patient to rule out pnemothorax once before the surgery and another after the end of surgery while the patient is being anesthetized.\n* Patients that will experience pneuomothorax will be excluded from the study, and will be treated according to its size.\n* Follow up of the patient for 24 hours postoperative to record the VAS score continuously, with giving increments of pethidine intravenously to relief pain.",[27,136],"Breast Cancer",[136,27,138,139,112,140,141,142],"Peripheral Nerve Block","Dexmedetomidine","Serratus Anterior Plane Block","Ultrasound Guided","Adult Female","2025-04-20",{"date":145,"type":40},"2025-04-27",{"date":147,"type":40},"2025-03-03",{"date":149,"type":21},"2026-03-04",{"name":151,"class":47},"Kholoud Usama"]