[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"moral-distress\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:moral-distress":34},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,55],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":39,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":49,"leadSponsor":51,"locationsCount":54},"100644320","research-patients-and-clinical-research-nurses-exploring-their-experiences-of-taking-part-in-clinical-research-in-the-nhs-100644320",false,"NCT07663058","Research-patientS and Clinical researcH Nurses: Exploring Their Experiences of tAking paRt in Clinical resEarch in the NHS","SHARE","Inclusion Criteria:\n\nINCLUSION CRITERIA FOR RESEARCH-PATIENTS\n\n* Research-patients aged above 18 years old.\n* Research-patients currently participating or have previously participated in adult clinical research at the age of 18 (or over) at GSTT.\n* Research-patients who are willing and able to provide informed consent.\n\nINCLUSION CRITERIA FOR CRNS Clinical research nurses (CRNs) currently working in adult clinical research at Guys and St Thomas' NHS Foundation Trust.\n\n• CRN willing and able to give consent.\n\nExclusion Criteria:\n\nEXCLUSION CRITERIA FOR RESEARCH-PATIENTS\n\n* Patients who showed an interest in taking part in research but were not recruited, e.g. due to screen failure, or ineligibility.\n* Research-patients recruited to research via proxy consent, e.g., next of kin.\n* Patients unable to provide informed consent, e.g., lacking mental capacity.\n* Research-patients considered vulnerable or at risk of harm, by the research team\n* Research-patients taking part in mental health or maternity trials or studies\n* Research-patients not fluent in English or not able to converse well in English\n\nEXCLUSION CRITERIA FOR CRNS\n\n* Clinical research midwives and clinical research nurses working in mental health, maternity, and paediatric research are excluded from this study.\n* CRNs not willing or unable to give consent.",true,"ALL","18 Years",{"count":20,"type":21},30,"ESTIMATED","OBSERVATIONAL","This PhD explores the views of clinical research nurses (CRNs) and research-patients as they take part in clinical research within their respective roles, i.e., as a specialised staff member and as a patient volunteer. Clinical research is supported by NHS England as the best way to improve patient care by finding out whether a new treatment is better than what is available. CRNs are specialist nurses who manage and coordinate clinical research. CRNs are responsible for the safe running of research; they ensure the right information is collected for the research\u002Ftrial to be successful. CRNs support the well-being of research-patients, by taking note of any new, or existing healthcare needs of research-patients while they take part in research. CRNs coordinate the activities that research requires, biological samples, scans, documentation. Balancing their responsibility towards research-patients, on the one hand, and research management, on the other, can bring unique challenges for the CRN. CRNs can feel conflicted between these two responsibilities, e.g., when they think that a drug trial, or the research activities in a study is at odds with the research-patient's best interest despite the research-patient's consent to take part in research. CRNs are tasked with maintaining\u002Ffacilitating recruitment of research-patients, this can be a challenging aspect of their role especially if they feel pressured to approach patients to take part in research. Currently, we know little about how CRNs balance these two responsibilities, or what other problems CRNs have in their everyday role when balancing these responsibilities. Finding out more about these aspects of the CRN role is important because it may not only improve job experience but can also give a better understanding of what can be changed to improve how CRN perform their role which could ultimately improve research-patients' experience of taking part in research. To address this issue, this PhD will explore CRNs and research-patients' views about clinical research, the challenges CRNs face, how CRNs balance their responsibilities, and what role does the relationship between CRNs, and research-patients play overall in what they say about their experience of taking part in clinical research. The researcher will interview and shadow CRNs and research-patients at a central NHS Hospital. This is a LISS\u002FESRC funded PhD at King's College London and supported by Guy's and St Thomas NHS Foundation Trust.",[25,26,27,28,29,30,31,32,33,34,35,36,37,38],"Experiences","Lived Experiences","Research Participation","Research Subjects","Nurse's Role","Research Ethics","Therapeutic Misconception","Clinical Research Nurses","Research Nurses","Moral Distress","Ethical Dilemma","Research-Patients","Research Nurse and Research-Patient Interactions","Research Experience",[32,36,38,31,40,41],"Ethical Challenges","CRN Dual Role","NOT_YET_RECRUITING","2026-06-23",{"date":45,"type":46},"2026-06-26","ACTUAL",{"date":48,"type":21},"2026-08-30",{"date":50,"type":21},"2028-12-30",{"name":52,"class":53},"Guy's and St Thomas' NHS Foundation Trust","OTHER",1,{"id":56,"slug":57,"hasResults":11,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":16,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":63,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":65,"conditions":66,"keywords":67,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":54},"100580363","the-interplay-between-moral-distress-moral-resilience-and-mental-health-outcomes-among-neonatal-care-providers-100580363","NCT06836323","The Interplay Between Moral Distress, Moral Resilience, and Mental Health Outcomes Among Neonatal Care Providers","Exploring the Interplay Between Moral Distress, Moral Resilience, and Mental Health Outcomes Among Neonatal Care Providers","MoD","Inclusion Criteria:\n\n* Neonatal care providers working in a Department of Neonatology or a Department of Pediatric Intensive Care Medicine with focus on neonates, regardless of professional group or level of education (all health care professionals - e.g., nurses, neonatologists, intensivists, residents, psychologists, fellows, nursing and medical students).\n* At least 2 weeks of practice on the unit in the 3 months prior to each survey.\n* Written informed consent\n* Self-reported sufficient knowledge of the German language\n\nExclusion Criteria:\n\n* Self-reported acute psychiatric illness",{"count":64,"type":21},800,"Due to highly specialized medical care neonatal care providers are faced with numerous responsibilities which makes neonatal care a particularly challenging and stressful work environment. Moral Distress (MoD) is an increasingly perceived phenomenon, which occurs if a person is prevented from doing what she or he believe is morally right. Such situations are common in neonatal care and MoD has severe negative consequences, including burnout and resignation. There is a significant gap of knowledge on the prevalence of MoD among neonatal care providers. In addition, the complex interplay between MoD and burnout is largely unexplored. The understanding of MoD and the exploration of possible influencing factors are indispensable prerequisites for effectively targeting and mitigating the negative effects of MoD.\n\nAims: This project aims at providing normative data on the prevalence of MoD among neonatal care providers in German speaking Switzerland. This project will further explore the interplay between MoD and burnout as well as the role of protective and reinforcing factors including moral resilience, perceived stress, mental health and workload.\n\nDesign: A prospective observational mixed methods study will be conducted among neonatal care providers in Swiss secondary and tertiary care neonatal units. Over a one-year period, neonatal care providers will be repeatedly asked to answer a survey on MoD and associated outcomes. Semi-structured interviews will be performed to gain detailed information on what constitutes MoD.\n\nSignificance: The study results will allow a robust assessment of the extent of MoD in the neonatal care environment. They will further provide information regarding the feasibility of a continuous screening approach. In the effort to optimize the work environment of healthcare workers in ethically complex clinical settings, in-depth exploration MoD is indispensable. The results of this study may help establish an approach to continuous assessment, and thus provide a basis for verifiable interventions.",[34],[68,69,70,71,72,73],"Neonatal intensive care","Preterm","Moral distress","Resilience","Burnout","Workload","RECRUITING","2025-02-17",{"date":77,"type":46},"2025-02-20",{"date":79,"type":46},"2024-01-22",{"date":81,"type":21},"2025-08-04",{"name":83,"class":53},"Insel Gruppe AG, University Hospital Bern"]