[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"mosaicism\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:mosaicism":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,51,81],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":32,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100370937","pregnancy-and-developmental-outcomes-after-transfer-of-reportedly-aneuploid-or-mosaic-embryos-100370937",false,"NCT04109846","Pregnancy and Developmental Outcomes After Transfer of Reportedly Aneuploid or Mosaic Embryos","Transfer of Aneuploid or Mosaic Embryos Following Preimplantation Genetic Testing","TAME","Inclusion Criteria:\n\n* Available aneuploid or mosaic embryos\n* No other acceptable embryos available\n* Willing to travel to Stanford for treatment\n* English language fluency\n\nExclusion Criteria:\n\n* Use of international donor eggs or sperm not tested according to FDA guidelines.\n* Living outside the United States\n* Embryos with Triploidy are not eligible for transfer in this protocol",true,"FEMALE","18 Years","55 Years",{"count":22,"type":23},300,"ESTIMATED","INTERVENTIONAL",[26],"NA","To determine how often embryos reported to be abnormal by preimplantation genetic testing result in liveborn infants. To evaluate whether the pregnancies that result from these embryos are higher risk for complications and whether the resulting babies have higher risk for health or developmental issues in the first five years after birth.",[29,30,31],"Aneuploidy","Mosaicism","Pregnancy Outcome",[33,34,35,36,37],"Preimplantation Genetic Testing for Aneuploidy","Preimplantation Genetic Screening","embryo transfer","mosaic","aneuploid","RECRUITING","2026-04-21",{"date":41,"type":42},"2026-04-24","ACTUAL",{"date":44,"type":42},"2019-04-11",{"date":46,"type":23},"2039-04-01",{"name":48,"class":49},"Stanford University","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":59,"minAge":4,"maxAge":4,"enrollmentInfo":60,"targetDuration":62,"studyType":63,"phases":4,"briefSummary":64,"conditions":65,"keywords":70,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":5},"100404078","li-fraumeni--tp53-lift-up-understanding-and-progress-100404078","NCT04541654","Li-Fraumeni & TP53 (LiFT UP): Understanding and Progress","Li-Fraumeni & TP53: Understanding and Progress (LiFT UP)","LiFT_UP","Inclusion Criteria:\n\n* Individuals with a TP53 pathogenic or likely pathogenic variant identified in blood or saliva,\n* Individuals with variants of uncertain significance in TP53 may be eligible at the PI's discretion,\n* Blood relatives of individuals with a TP53 variant, who may be presumed obligate carriers or healthy controls,\n* Individuals who meet Classic or Chompret LFS criteria whether or not they have a TP53 gene variant,\n* Individuals may enroll their deceased relatives in the study.\n* Individuals with a known TP53 variant that is not LFS, but rather ACE, CHIP, or mosaicism.\n* Individuals participating in other LFS studies can still enroll in LiFT UP. Investigators may be collaborators.\n\nExclusion Criteria:\n\n* Individuals who decline to sign consent\n* Individuals who are unable to give consent or assent and are without a designated healthcare proxy","ALL",{"count":61,"type":23},1500,"5 Years","OBSERVATIONAL","The purpose of this research study is to learn more about variants in the TP53 gene both associated with Li-Fraumeni Syndrome (LFS), a hereditary cancer risk condition, and TP53 variants found in the blood for other reasons (e.g. ACE\u002FCHIP and mosaicism).",[66,67,68,69,30],"Li-Fraumeni Syndrome","TP53 Gene Mutation","Hereditary Cancer Syndrome","Clonal Hematopoiesis",[66,71,68,69,30],"TP53 Gene Mutation (Variant)","2026-03-24",{"date":74,"type":42},"2026-03-27",{"date":76,"type":42},"2020-09-15",{"date":78,"type":23},"2032-12-31",{"name":80,"class":49},"Dana-Farber Cancer Institute",{"id":82,"slug":83,"hasResults":11,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":4,"eligibilityCriteria":87,"healthyVolunteers":11,"sex":18,"minAge":4,"maxAge":4,"enrollmentInfo":88,"targetDuration":62,"studyType":63,"phases":4,"briefSummary":90,"conditions":91,"keywords":93,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":50},"100595752","non-euploid-embryo-transfer-neet-registry-100595752","NCT07036536","Non-Euploid Embryo Transfer (NEET) Registry","The NEET Registry: a Prospective, Observational Study for Outcomes of Non-euploid Embryo Transfers (NEET)","Inclusion Criteria:\n\n* Patient is planning a non-euploid embryo transfer (NEET) at a fertility clinic in The Prelude Network.\n* Patient has signed informed consent to participate in the registry.\n\nExclusion Criteria:\n\n* Not applicable",{"count":89,"type":23},1000,"The NEET Registry is a registry to track and study the outcomes of non-euploid embryo transfers (NEET) in The Prelude Network",[92,30,29],"Infertility",[94,95,37,96],"IVF","PGT-A","FET","2025-06-24",{"date":99,"type":42},"2025-06-25",{"date":101,"type":42},"2024-09-23",{"date":103,"type":23},"2030-12",{"name":105,"class":106},"Inception Fertility Research Institute, LLC","INDUSTRY"]