[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"motivation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:motivation":35},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,23,0,[8,60,90,123,147,176,201,223,255,286,307,328,351,382,411,441,463,488,515,542,571,591,612],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":40,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":48,"lastUpdatePostDateStruct":49,"startDateStruct":52,"completionDateStruct":54,"leadSponsor":56,"locationsCount":59},"100644951","the-impact-of-enhanced-music--natural-visuals-on-emotional-health-100644951",false,"NCT07676110","The Impact of Enhanced Music & Natural Visuals on Emotional Health","Impacts of Music, Audio Enhancements, Audio Guidance, and Visuals on Physical and Emotional Well-being. (Emotional Health - Longitudinal 1 Randomized, Controlled Multi-center Study)","Inclusion Criteria:\n\n* You are 13 years of age or older\n* You can read, write, and speak English at a 5th-grade level or higher\n* You are legally capable of providing informed consent (adult participants) or capable of providing assent (child participants)\n* To the best of your knowledge, you are willing and able to commit to the session(s) and activities of this study\n* You are willing and able to use the sound-delivery and data-collection apparatus of this study\n* You are willing to use your own personal equipment. Depending on the study, you may need to have your own ear buds\u002Fheadphones and\u002For a \"smart\" device with internet and\u002For Bluetooth access (e.g., smartphone, iPad).\n* You have normal hearing in both ears.\n* You never experience ringing noises or buzzing sensations in your ears (tinnitus)\n* You do not use a heart\u002Fcardiac pacemaker and do not have any history of cardiac rhythm disturbances, such as cardiac conduction delays or blocks\n* You have no known history of fainting, fainting, spells or seizures, spinning sensations, or trouble with balance (medical terms include epilepsy, seizures, syncope, vertigo, nystagmus)\n* You do not use of any of the following medications: Beta blockers, steroids, ephedrine, acute anti-anxiety medication (e.g., benzodiazepines such as diazepam\u002FValium, lorazepam\u002FAtivan or clonazepam\u002FKlonopin), or acute or chronic pain medications (including narcotics and codeine)\n* For any study session, you will not be under the influence of any substances that could prevent safe participation and will not have consumed e.g., alcohol, THC, Psilocybin, or other mood-altering drugs in the 12 hours preceding the session.\n\nExclusion Criteria:\n\n\\-",true,"ALL","13 Years",{"count":20,"type":21},200,"ESTIMATED","INTERVENTIONAL",[24],"NA","The investigators are conducting research on factors related to the self-regulation of mood and arousal states across a range of everyday activities as well as different levels of stress. Behavioral interventions-such as meditation, listening to music, or visualizing art or nature-offer important alternatives and\u002For adjunctive strategies to pharmaceutical tools or other mechanisms supporting physical and emotional well-being. This research will expand on the knowledge base regarding the impact of biophysical stimulation and\u002For frame of mind on an individual's self-directed management of physical and emotional health. Motivation, confidence, and composure are critical aspects of self-efficacy, framing a person's mindset to make healthy choices across daily activities.\n\nThe research in this protocol is carried out across multiple sites and studies by means of digital tools and a consistent participant experience workflow. Together, these resources are intended to support individuals across multiple self-directed experiences utilized in the maintenance of their basic health. Before, during, and after session experiences, the participant provides objective (physiological) responses and\u002For subjective (self-report) responses and reflections; some studies also include interviews or focus groups. The combined set of responses can be summarized, connected to other measures, and input to machine learning models to improve personalization of stimuli. By studying the effects of soundBrilliance experiences across a variety of contexts and participant samples, the investigators can better refine each element of the stimulus to improve satisfaction, tolerance, and targeted outcomes.",[27,28,29,30,31,32,33,34,35,36,37,38,39],"Emotion Management Skills","Lifestyle, Healthy","Lifestyle Intervention","Recovery","Exercise and Recovery","Exercise Training","Anxiety and Mood Disorders","Sleep","Motivation","Comfort","Pain Management","Rehabilitation","Creativity and Mindfulness",[41,42,43,44,45,46],"Music","Visuals","Visual Imagery","Biophysical Stimuli","Emotional Health","Emotional Management","RECRUITING","2026-06-23",{"date":50,"type":51},"2026-06-30","ACTUAL",{"date":53,"type":51},"2026-05-25",{"date":55,"type":21},"2027-06",{"name":57,"class":58},"soundBrilliance LLC","INDUSTRY",3,{"id":61,"slug":62,"hasResults":11,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":4,"eligibilityCriteria":66,"healthyVolunteers":11,"sex":67,"minAge":68,"maxAge":4,"enrollmentInfo":69,"targetDuration":4,"studyType":22,"phases":71,"briefSummary":72,"conditions":73,"keywords":4,"overallStatus":79,"whyStopped":4,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":4},"100641442","effect-of-maternal-awareness-of-the-duration-fo-the-second-stage-of-labor-on-the-length-of-the-second-stage-100641442","NCT07653334","Effect of Maternal Awareness of the Duration fo the Second Stage of Labor on the Length of the Second Stage","Effect of Maternal Awareness of the Duration fo the Second Stage of Labor on the Length of the Second Stage: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Singleton, cephalic presentation\n* Gestational age ≥ 37+0 weeks at delivery.\n* Reached the second stage of labor (complete cervical dilation with intention to proceed with vaginal delivery).\n* Ability to understand study information and provide informed consent.\n\nExclusion Criteria:\n\n* Planned cesarean delivery.\n* Intrauterine fetal demise.\n* Critical maternal illness requiring intensive hemodynamic or respiratory support.\n* Cognitive impairment or language barrier precluding consent and comprehension of instructions.\n* Abnormal fetal heart tracing requiring operative vaginal delivery\n* Shoulder dystocia requiring maneuvers other than McRoberts and suprapubic pressure","FEMALE","18 Years",{"count":70,"type":21},240,[24],"This study aims to understand whether informing laboring patients about how long they have been pushing during the second stage of labor affects the length of that stage and the overall childbirth experience.\n\nThe second stage of labor is the period from when the cervix is fully dilated until the baby is delivered. When this stage lasts longer than expected, it can increase the chance of complications such as assisted delivery with vacuum or forceps, cesarean delivery, heavy bleeding after delivery, and certain neonatal complications. Although healthcare providers routinely track the duration of the second stage, patients are not always told how long they have been pushing. Some providers believe that sharing this information may help motivate patients and improve their sense of control, while others worry that it could increase stress or pressure.\n\nIn this study, participants will be randomly assigned to one of two groups. In the intervention group, patients will receive regular updates about how long they have been pushing during the second stage of labor, and a visible timer will be used. In the comparison group, patients will receive standard care, which does not include structured time updates.\n\nAll participants will receive the same medical care otherwise. The study will measure the length of the second stage of labor as well as maternal and neonatal outcomes such as the type of delivery, postpartum complications, newborn health indicators, and admission to the neonatal intensive care unit. Participants will also be asked to complete a short questionnaire after delivery about their childbirth experience and sense of control during labor.\n\nThe risks of this study are minimal because the intervention involves only providing information about time during labor. There are no changes to medical treatment or standard care. The information gained from this research may help clinicians improve communication with patients during labor and may identify simple ways to enhance patient experience and potentially improve labor outcomes.\n\nParticipation in the study is voluntary, and patients may decline or withdraw at any time without affecting the care they receive.",[74,35,75,76,77,78],"Labor, Second Stage","Feedback, Psychological","Self Efficacy","Personal Satisfaction","Perception","NOT_YET_RECRUITING","2026-06-15",{"date":82,"type":51},"2026-06-17",{"date":84,"type":21},"2026-07-01",{"date":86,"type":21},"2029-07-01",{"name":88,"class":89},"Valmiki Vijay Seeraj","OTHER",{"id":91,"slug":92,"hasResults":11,"nctId":93,"briefTitle":94,"officialTitle":94,"acronym":95,"eligibilityCriteria":96,"healthyVolunteers":11,"sex":17,"minAge":68,"maxAge":4,"enrollmentInfo":97,"targetDuration":4,"studyType":22,"phases":99,"briefSummary":100,"conditions":101,"keywords":104,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":116,"completionDateStruct":118,"leadSponsor":120,"locationsCount":122},"100444263","understanding-motivation-in-parkinsons-patients-through-neurophysiology-100444263","NCT05065151","Understanding Motivation in Parkinson's Patients Through Neurophysiology","MPPN","Inclusion Criteria:\n\n* Has Parkinson's Disease or Dystonia\n* Has Medtronic Percept or RC+S DBS device implanted in either GPI or STN\n* Has DBS device implanted either bilaterally or unilaterally\n* Male or female\n* More than 1 month post-DBS surgery\n\nExclusion Criteria:\n\n* Severe cognitive impairments\n* Has MOCA score below 20\n* Pregnancy\n* Age less than 18 years old",{"count":98,"type":21},70,[24],"The study aims to better understand motivation and value-based decision-making in Parkinson's patients through neurophysiology using Medtronic's Percept DBS device. By combining behavioral tasks with neural recordings, the study seeks to uncover how DBS affects motivation, particularly in relation to effort, reward, and timing.",[102,103,35],"Parkinson Disease","Deep Brain Stimulation",[105,106,107,108,103,109,102,110,111,112],"Parkinson's","Medtronic","Percept","DBS","Parkinson's Disease","PD","Reward-based decision making","Task","2026-06-03",{"date":115,"type":51},"2026-06-05",{"date":117,"type":51},"2021-10-30",{"date":119,"type":21},"2030-12-01",{"name":121,"class":89},"University of California, San Francisco",1,{"id":124,"slug":125,"hasResults":11,"nctId":126,"briefTitle":127,"officialTitle":127,"acronym":4,"eligibilityCriteria":128,"healthyVolunteers":16,"sex":67,"minAge":68,"maxAge":4,"enrollmentInfo":129,"targetDuration":4,"studyType":131,"phases":4,"briefSummary":132,"conditions":133,"keywords":4,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":138,"lastUpdatePostDateStruct":139,"startDateStruct":141,"completionDateStruct":143,"leadSponsor":145,"locationsCount":122},"100624711","relationship-between-the-severity-of-sleep-deprivation-in-the-first-48-hours-postpartum-breastfeeding-motivation-and-breastfeeding-success-100624711","NCT07413185","Relationship Between the Severity of Sleep Deprivation in the First 48 Hours Postpartum, Breastfeeding Motivation, and Breastfeeding Success","Inclusion Criteria:\n\n* Primiparous or multiparous women aged 18 years and older\n* Having a healthy term delivery\n* Infant not admitted to the neonatal intensive care unit (NICU)\n* Initiated breastfeeding within the first 48 hours postpartum\n\nExclusion Criteria:\n\n* Complications requiring sedation\n* Severe postpartum hemorrhage\n* Severe postoperative pain or need for narcotic analgesics",{"count":130,"type":21},167,"OBSERVATIONAL","The postpartum period is a critical time marked by significant physiological and psychosocial changes that can affect sleep, emotional well-being, and breastfeeding behaviors. Previous studies indicate that mode of delivery and sleep quality are closely associated with breastfeeding outcomes, with cesarean birth often linked to poorer sleep and lower breastfeeding success. Evidence also suggests that postpartum sleep disturbances are related to reduced breastfeeding self-efficacy, lower motivation, fatigue, depressive symptoms, and shorter breastfeeding duration.\n\nHowever, the literature lacks studies that evaluate insomnia severity, breastfeeding motivation, and breastfeeding success simultaneously-particularly during the first 48 hours after birth. This analytical study aims to assess insomnia severity, breastfeeding motivation, and breastfeeding success (LATCH) within the first 48 postpartum hours and to examine the relationships among these variables. Findings are expected to support early postpartum clinical interventions to improve maternal and infant health outcomes.",[134,34,135,35,136,137],"Postpartum Period","Breastfeeding","Cesarean Section","Lactation","2026-03-23",{"date":140,"type":51},"2026-03-24",{"date":142,"type":51},"2026-03-12",{"date":144,"type":21},"2027-02-23",{"name":146,"class":89},"Acibadem University",{"id":148,"slug":149,"hasResults":11,"nctId":150,"briefTitle":151,"officialTitle":151,"acronym":152,"eligibilityCriteria":153,"healthyVolunteers":16,"sex":17,"minAge":68,"maxAge":154,"enrollmentInfo":155,"targetDuration":4,"studyType":22,"phases":157,"briefSummary":158,"conditions":159,"keywords":162,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":167,"lastUpdatePostDateStruct":168,"startDateStruct":170,"completionDateStruct":172,"leadSponsor":174,"locationsCount":122},"100612302","neural-bases-of-motivation-100612302","NCT07251816","Neural Bases of Motivation","MOTIVACTION","Inclusion Criteria:\n\n* Healthy volunteers aged between 18 and 40 years\n* Participants without confounding factors such as neural alterations related to neurological pathology, whether neurodegenerative (e.g., Alzheimer, Parkinson, Huntington, multiple sclerosis, amyotrophic lateral sclerosis), motor (e.g., dystonia, essential tremors, cerebellar syndrome), traumatic (e.g., traumatic brain injury, medulla lesion) or psychiatric pathologies, whether mood disorders (e.g., depression, bipolarity), anxious troubles (e.g., obsessional compulsive disorder, post-traumatic stress disorder), psychotic (e.g., schizophrenia, delusion), substance-related (e.g., alcool, drug or medicine addiction), food-related (e.g., anorexia, bulimia), neurodevelopmental (e.g., autism, attention-deficit with hyperactivity disorder) or personality (e.g., borderline personality disorder, antisocial personality disorder, obsessive-compulsive disorder).\n* Participants affiliated with a compulsory social security scheme.\n\nExclusion Criteria:\n\n* Persons deprived of liberty by judicial or administrative decisions.\n* Pregnant women, women in labor or breastfeeding women\n* Persons admitted to a health or social institution for purposes other than research.\n* Adults under legal protection measures (e.g., guardianship or curatorship).\n* Participation in other interventional research with an ongoing non-inclusion period.\n* Neurological or psychiatric disorders.\n* Use of tricyclic antidepressants (amitriptyline, clomipramine, imipramine, nortriptyline), neuroleptics (chlorpromazine, haloperidol, risperidone, olanzapine, quetiapine), or recreational drugs within the past 48 hours.\n* Regular use of recreational drugs.\n* Sleep deprivation (\\\u003C 5 hours regularly over the last 3 months)\n* Left-handedness or ambidexterity.\n* Physical injuries impacting motor tasks.\n* Presence of metal implants in the head (excluding oral fillings).\n* Presence of implanted medical devices (e.g., pacemaker).\n* Presence of metallic injuries in the eyes.\n* Claustrophobia.\n* Piercings incompatible with MRI procedures.\n* Contraindication to MRI\n* Persons who refused to be informed of eventual medical anomalies discovered by the MRI\n* Personal or family history (first-degree relatives) of epilepsy or seizures. Severe and\u002For frequent headaches (only for participants receiving transcranial magnetic stimulation, e.g preparatory experience 1 and experience 1)\n* Baldness impeding electrode placement (only for participants receiving transcranial electrical stimulation and EEG measurements, e.g experiments 2, 3 and 4)\n* Facial or ear pain and\u002For recent ear trauma (only for participants receiving transcutaneous vagal nerve stimulation, e.g experiment 5)","40 Years",{"count":156,"type":21},204,[24],"Effort-based decisions are essential in daily life but strongly impaired in apathy across various brain disorders. Now, significant research to unveil the neural causes of apathy is needed. A crucial corollary to this is the need to identify the brain network and neural mechanisms underlying effort-based decisions.\n\nA fronto-striatal network and the noradrenergic system are involved in effort-based decision-making and apathy. Further, motor cortical structures may play a role in effort-based decision-making. However, the role of circuits connecting the fronto-striatal network and the noradrenergic system to the motor structures has been disregarded so far.\n\nNon-invasive brain stimulation methods provide a unique and safe means to test the causal role of connectivity changes between fronto-subcortical and motor structures in effort-based decision-making.\n\nIt's now necessary to have an integrative, connectionnist framework to uncover the causal role of connectivity changes between fronto-subcortical and motor structures in effort-based decision-making.\n\nThe overarching goal of the present research protocol is to establish an integrative framework testing the causal role of connectivity within recurrent, bidirectional circuits between fronto-subcortical circuits and motor structures in effort-based decision-making. To achieve this overarching goal, investigators will quantifiy the causal role of effective connectivity and oscillatory synchrony in these circuits on effort-related behavior using a non-invasive brain stimulation strategy. Further, a secondary aim is to identify potential non-invasive brain stimulation methods that could increase engagement in effortful behavior, paving the way for translational clinical applications in the context of apathy.\n\nThe investigators hypothesize that effort-based decision-making in healthy subjects is governed by bidirectional interactions between fronto-subcortical circuits and motor structures such as the primary motor cortex, mediated by oscillatory synchrony in specific frequency bands (e.g., theta and gamma bands). Accordingly, they hypothesize that transient, non-invasive modulation of connectivity and oscillatory synchrony between these structures in healthy human subjects will directly modulate their decision to engage in effort. Specifically, five experiments will use complementary approaches to test the hypothesis.",[160,35,161],"Healthy Volunteers","Action",[163,35,164,165,166],"Healthy volunteers","Apathy","Decision-making","Effort processing","2026-01-20",{"date":169,"type":51},"2026-01-22",{"date":171,"type":51},"2026-01-14",{"date":173,"type":21},"2033-01",{"name":175,"class":89},"Hospices Civils de Lyon",{"id":177,"slug":178,"hasResults":11,"nctId":179,"briefTitle":180,"officialTitle":180,"acronym":181,"eligibilityCriteria":182,"healthyVolunteers":11,"sex":17,"minAge":68,"maxAge":183,"enrollmentInfo":184,"targetDuration":4,"studyType":22,"phases":186,"briefSummary":187,"conditions":188,"keywords":4,"overallStatus":79,"whyStopped":4,"lastUpdateSubmitDate":192,"lastUpdatePostDateStruct":193,"startDateStruct":195,"completionDateStruct":197,"leadSponsor":199,"locationsCount":4},"100618633","effect-of-critical-thinking-disposition-program-on-developing-reflective-thinking-and-motivation-to-learn-among-nursing-students-100618633","NCT07334158","Effect of Critical Thinking Disposition Program on Developing Reflective Thinking and Motivation to Learn Among Nursing Students","CTDP","Inclusion Criteria:\n\n* Willing to participate and able to attend all program sessions.\n\nNo prior exposure to critical thinking training programs.\n\nExclusion Criteria:\n\n* Students with learning difficulties or any limitations that prevent active participation in the program.\n\nStudents who miss more than 50% of the program sessions.\n\nStudents participating in external programs aimed at enhancing critical thinking during the study period.","20 Years",{"count":185,"type":21},243,[24],"Study Title:\n\nEffect of Critical Thinking Disposition Program on Developing Reflective Thinking and Motivation to Learn among Nursing Students\n\nStudy Description:\n\nThis study aims to investigate the effect of a Critical Thinking Disposition Program on nursing students' reflective thinking and motivation to learn. In the rapidly evolving healthcare environment, nurses must possess both critical thinking skills and disposition to make accurate clinical judgments and provide high-quality professional care. Many novice nurses lack critical thinking disposition, which can result in inaccurate clinical judgments and an inability to identify causes of problems.\n\nThe program will target nursing students to enhance their internal motivation to think critically, solve problems, evaluate ideas, and make informed decisions. The intervention focuses on developing cognitive strategies, attitudes, and behaviors that support self-motivated learning and professional competence. Outcomes will be measured by evaluating students' reflective thinking and motivation to learn before and after the program.\n\nPrimary Outcome Measures:\n\nImprovement in reflective thinking scores\n\nIncrease in motivation to learn scores\n\nSecondary Outcome Measures:\n\nDevelopment of critical thinking disposition attributes such as truth-seeking, open-mindedness, analyticity, inquisitiveness, self-confidence, and maturity",[189,190,35,191],"Critical Thinking","Reflective","Nursing Students","2026-01-03",{"date":194,"type":51},"2026-01-12",{"date":196,"type":21},"2026-01",{"date":198,"type":21},"2026-12",{"name":200,"class":89},"Mansoura University",{"id":202,"slug":203,"hasResults":11,"nctId":204,"briefTitle":205,"officialTitle":206,"acronym":4,"eligibilityCriteria":207,"healthyVolunteers":16,"sex":17,"minAge":68,"maxAge":208,"enrollmentInfo":209,"targetDuration":4,"studyType":22,"phases":211,"briefSummary":212,"conditions":213,"keywords":4,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":214,"lastUpdatePostDateStruct":215,"startDateStruct":217,"completionDateStruct":219,"leadSponsor":221,"locationsCount":122},"100612561","glucose-and-motivation-states-100612561","NCT07255183","Glucose and Motivation States","Impact of Blood Glucose on Motivation States: A Double-Blind Placebo-Controlled Study","Inclusion Criteria:\n\n* Body mass index 18-30 m\u002Fkg\\^2\n* Health Status: generally healthy; no cardiopulmonary\u002Fmetabolic\u002Forthopedic disease or limitations\n* Blood Pressure: excluded with SBP of 130+ mmHg or DBP of 80+ mmHg\n* Glucose Status: excluded and instructed to seek medical consultation if fasting values are \\\u003C70 mg\u002Fdl or \\>125 mg\u002Fdl; included but encouraged to seek medical consultation if fasting values are 100-125 mg\u002Fdl\n\nExclusion Criteria:\n\n* None","45 Years",{"count":210,"type":21},40,[24],"The purpose of this study is to evaluate how motivation is impacted by exercise and beverage consumption. You will be asked to report to our lab for 5 visits each separated by 2+ days over a period of 2-3 weeks.",[35],"2025-11-19",{"date":216,"type":51},"2025-11-28",{"date":218,"type":51},"2025-10-30",{"date":220,"type":21},"2026-08",{"name":222,"class":89},"University of South Florida",{"id":224,"slug":225,"hasResults":11,"nctId":226,"briefTitle":227,"officialTitle":228,"acronym":4,"eligibilityCriteria":229,"healthyVolunteers":11,"sex":17,"minAge":154,"maxAge":4,"enrollmentInfo":230,"targetDuration":4,"studyType":22,"phases":231,"briefSummary":234,"conditions":235,"keywords":241,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":246,"lastUpdatePostDateStruct":247,"startDateStruct":249,"completionDateStruct":251,"leadSponsor":253,"locationsCount":122},"100601636","phase-1-accelerated-rtms-vs-sham-for-stroke-apathy-100601636","NCT07113067","Accelerated rTMS vs. Sham for Stroke Apathy","Accelerated rTMS for Post-stroke Apathy: A Double-blind Randomized Controlled Trial","Inclusion Criteria:\n\n* 40 years old or greater\n* Right- or left-hemisphere ischemic or hemorrhagic stroke with at least 6 months chronicity\n* Symptomatic apathy as confirmed by (A) total score on the Apathy Evaluation Scale by the participant or the caregiver\u002Fco-participant (AES) of ≥39\n* Ability to participate in psychometric testing and cognitive tasks\n* Intact cortex at the TMS target site as confirmed by pre-treatment MRI\n* Ability to have a co-participant\u002Fcaregiver who meets the criteria as detailed below.\n\nExclusion Criteria:\n\n* Primary extra-axial hemorrhage (subdural or subarachnoid) without ischemic stroke or intraparenchymal hemorrhage\n* Concomitant neurological disorders affecting motor or cognitive function (e.g. dementia)\n* Moderate or severe global aphasia\n* Visual impairment precluding completion of cognitive tasks\n* Presence of contraindications to MRI or TMS including electrically, magnetically or mechanically activated metal or nonmetal implants such as cardiac pacemaker, intracerebral vascular clips or any other electrically sensitive support system;\n* Pregnancy (to be later confirmed by UPT in any premenopausal female participants)\n* History of a seizure disorder\n* Preexisting scalp lesion, wound, bone defect, or hemicraniectomy\n* Claustrophobia precluding ability to undergo an MRI\n* Active substance use disorder\n* Psychotic disorders\n* Bipolar 1 Disorder\n* Acute suicidality as assessed by the Columbia Suicide Severity Rating Scale (C-SSRS)30 or suicide attempt in the previous year\n\nFor CO-PARTICIPANT\u002FCAREGIVER:\n\nInclusion Criteria:\n\n* Age 18 years or older\n* Is a reliable informant who has at least weekly contact with the participant and can speak to the participant's cognitive and everyday functioning.\n\nExclusion Criteria:\n\n\\- Unable to engage with study procedures in which Co-Participant input is needed.",{"count":210,"type":21},[232,233],"PHASE1","PHASE2","Apathy is a common set of symptoms seen in many people following a stroke. Apathy occurs when a person has lost motivation, becomes withdrawn, and stops doing things that used to be important to them. Apathy has a large negative impact on a person's quality of life, and can also have a large impact the people who take care of them. There are currently no FDA-approved treatments to help with apathy, and other services like therapy may be difficult to access for people who have had a stroke. To address this problem, investigators are conducting a study to find out if a form of treatment called repetitive transcranial magnetic stimulation (rTMS) can be safe and helpful for people struggling with apathy after a stroke. This study will apply a new form of rTMS which can be delivered quickly to a part of the brain called the medial prefrontal cortex (mPFC). This study will help establish whether this treatment is safe, comfortable, and effective for people with apathy after a stroke, and will help researchers develop new forms of treatment.",[164,236,237,238,239,35,240],"Stroke","Stroke Sequelae","Stroke\u002FBrain Attack","Stroke\u002F Cerebrovascular Accident (Ischemic or Hemorrhagic)","Abulia",[242,236,243,164,244,35,240,245],"Depression","Stroke Recovery","TMS","Amotivation","2025-10-21",{"date":248,"type":51},"2025-10-22",{"date":250,"type":51},"2025-08-08",{"date":252,"type":21},"2027-06-30",{"name":254,"class":89},"Medical University of South Carolina",{"id":256,"slug":257,"hasResults":11,"nctId":258,"briefTitle":259,"officialTitle":260,"acronym":4,"eligibilityCriteria":261,"healthyVolunteers":11,"sex":17,"minAge":262,"maxAge":263,"enrollmentInfo":264,"targetDuration":4,"studyType":22,"phases":266,"briefSummary":267,"conditions":268,"keywords":270,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":277,"lastUpdatePostDateStruct":278,"startDateStruct":280,"completionDateStruct":282,"leadSponsor":284,"locationsCount":122},"100605191","motivation-for-daily-living-skills-100605191","NCT07159308","Motivation for Daily Living Skills","Enhancing Motivation to Complete Daily Living Skills Among Transition-aged Autistic Youth","Inclusion Criteria for Autistic Teens and Young Adults:\n\n* Age 16-25 years\n* Participants reporting an autism diagnosis from a qualified provider (Psychiatrist, Psychologist, Developmental Pediatrician, Neurologist). When possible, diagnosis will be confirmed through the Children's Hospital of Philadelphia (CHOP) Electronic Health Record (EHR).\n* Must identify an important person who is able to communicate by understanding and speaking full sentences in English\n* Ability to communicate by understanding and using full sentences in English\n* Informed Consent\n* Be willing to have sessions audio- and video-recorded\n\nExclusion Criteria for Autistic Teens and Young Adults:\n\n* Diagnosis of Intellectual Disability\n* Participant is currently considered a suicide risk in the opinion of the Investigator or is currently demonstrating active suicidal or homicidal ideation or self-injurious behavior.\n* Current, comorbid psychiatric disorder with sufficiently intense symptoms in the opinion of the Investigator that these symptoms may confound treatment.\n* Changes to mental health treatment plan (ex. starting or ending therapy or psychotropic medications over the course of this intervention).\n* Participation in a prior trial of our intrinsic motivation condition\n\nInclusion Criteria for Important Person:\n\n* Age 18 years or older\n* Must attend at least 15 minutes of each treatment session\n* Ability to communicate by understanding and using full sentences in English\n* Informed consent\n* Be willing to have sessions audio- and video-recorded\n\nExclusion Criteria for Important Person:\n\n\\- Is not willing to support the autistic teen\u002Fyoung adult with their daily living skill goal","16 Years","25 Years",{"count":265,"type":21},180,[24],"The goal of this clinical trial is to enhance motivation to complete daily living skills among 16 to 25-year-old autistic teens and young adults. Here are the main questions the trial aims to answer:\n\nCan this trial improve motivation to complete daily living skills for skills that people know how to do but struggle to do them consistently?\n\nCan this trial improve completion of the daily living skill that the participant identifies they want to do more often?\n\nDo people report feeling more empowered to complete the daily living skill they want to do more often?\n\nAre there any characteristics of a person that make them more or less likely to benefit from the treatment?\n\nResearchers will compare treatments that target different types of motivation:\n\n* One treatment focuses on internal motivation and explores what is important to someone and then connect that value back to their daily living skill goal.\n* A second treatment focuses on external motivation and will explore a person finding outside sources of motivation, like rewards.\n* A third treatment will use a combination of both methods.\n\nAutistic teens and young adults enrolled in this study will also be asked to choose someone in their life to be involved in the study with them. This person is called an \"Important Person\" (IP) and can be anyone close to them, like a family member, friend, roommate, partner, etc. The IP will be expected to support the teen\u002Fyoung adult throughout this treatment.\n\nParticipants and their IPs will:\n\n* Complete five 'talk' therapy sessions that will last 60 to 90 minutes. The IPs will join the last 15 minutes of each session)\n* Be assigned to one of the three motivation treatments\n* Fill out questionnaires before the first session, after sessions 2 through 5, and 2 weeks after therapy ends",[269,35],"Autism Spectrum Disorder (ASD)",[271,35,272,273,274,275,276],"Interventions","Autism Spectrum Disorder","Daily Living Skills","Transition to Adulthood","behavior therapy","motivational interviewing","2025-10-01",{"date":279,"type":51},"2025-10-02",{"date":281,"type":51},"2025-09-15",{"date":283,"type":21},"2027-02",{"name":285,"class":89},"Children's Hospital of Philadelphia",{"id":287,"slug":288,"hasResults":11,"nctId":289,"briefTitle":290,"officialTitle":291,"acronym":4,"eligibilityCriteria":292,"healthyVolunteers":11,"sex":67,"minAge":68,"maxAge":4,"enrollmentInfo":293,"targetDuration":4,"studyType":131,"phases":4,"briefSummary":295,"conditions":296,"keywords":4,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":299,"lastUpdatePostDateStruct":300,"startDateStruct":302,"completionDateStruct":304,"leadSponsor":306,"locationsCount":122},"100598135","breastfeeding-myths-and-mothers-motivation-100598135","NCT07067554","Breastfeeding Myths and Mothers' Motivation","An Investigation of the Relationship Between Mothers' Susceptibility to Breastfeeding Myths and Their Motivation to Breastfeed","Inclusion Criteria:\n\n* Having an infant aged 0-6 months\n* Having breastfed the baby at least once\n* Voluntarily agreeing to participate in the study\n\nExclusion Criteria:\n\n* Having a physical or psychiatric health condition that prevents breastfeeding\n* Having had a multiple (twin or more) pregnancy\n* Exclusively formula-feeding the baby",{"count":294,"type":21},191,"Breast milk is a unique and irreplaceable source of nutrition for infants, offering protection against many common childhood diseases due to its natural sterility, accessibility, and immune-boosting antibodies. Exclusive breastfeeding for the first six months of life is critical for healthy growth, development, and immune support. Despite global recommendations by WHO and UNICEF, lack of knowledge and inadequate support continue to hinder optimal breastfeeding practices.\n\nOne major barrier is the persistence of cultural myths and misconceptions, such as \"colostrum should be discarded,\" or \"infants need water after every feeding.\" These unfounded beliefs may reduce mothers' confidence and lead to early cessation of breastfeeding or premature introduction of complementary foods.\n\nThis study aims to examine the relationship between mothers' belief in breastfeeding myths and their motivation to breastfeed. While prior research has explored each factor individually, no known studies have analyzed their interaction.",[135,297,298,35],"Maternal Behavior","Health Knowledge, Attitudes, Practice","2025-09-25",{"date":301,"type":51},"2025-09-30",{"date":303,"type":51},"2025-09-09",{"date":305,"type":21},"2026-07-30",{"name":146,"class":89},{"id":308,"slug":309,"hasResults":11,"nctId":310,"briefTitle":311,"officialTitle":312,"acronym":4,"eligibilityCriteria":313,"healthyVolunteers":16,"sex":17,"minAge":68,"maxAge":208,"enrollmentInfo":314,"targetDuration":4,"studyType":22,"phases":316,"briefSummary":317,"conditions":318,"keywords":4,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":319,"lastUpdatePostDateStruct":320,"startDateStruct":322,"completionDateStruct":324,"leadSponsor":326,"locationsCount":122},"100535869","informationseekingmesolimbicengagementstudy2-100535869","NCT06257433","InformationSeekingMesolimbicEngagementStudy2","The Influence of Mesolimbic-hippocampal Interactions on Episodic Memory During Active Information Seeking","Inclusion Criteria:\n\n* 20\u002F40 far acuity (either corrected or uncorrected)\n* In good medical health\n\nExclusion Criteria:\n\n* History of head injury\n* History of illness with Central Nervous Systems implications\n* On Medications that Affect blood flow response and alertness\n* Consumption of smoking and\u002For coffee 30 minutes prior to laboratory testing\n* Placement of a device contraindicated for magnetic resonance imaging including cardia pacemaker, aneurysm clip, cochlear implants, pregnancy, intra-uterine device, shrapnel, metal fragments in the eyes, neurostimulators\n* Weight \\> 250lbs\n* Claustrophobia",{"count":315,"type":21},80,[24],"Participants will complete a treasure task during neuroimaging where they have to learn which keys open a treasure chest, and then they are tested on the contents of the treasure chest.",[35],"2025-08-28",{"date":321,"type":51},"2025-09-05",{"date":323,"type":51},"2023-10-24",{"date":325,"type":21},"2026-08-01",{"name":327,"class":89},"Temple University",{"id":329,"slug":330,"hasResults":11,"nctId":331,"briefTitle":332,"officialTitle":333,"acronym":4,"eligibilityCriteria":334,"healthyVolunteers":16,"sex":17,"minAge":68,"maxAge":208,"enrollmentInfo":335,"targetDuration":4,"studyType":22,"phases":337,"briefSummary":338,"conditions":339,"keywords":4,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":342,"lastUpdatePostDateStruct":343,"startDateStruct":345,"completionDateStruct":347,"leadSponsor":349,"locationsCount":122},"100510704","mri-neurofeedback-and-brain-circuits-related-to-motivation-in-healthy-participants-100510704","NCT05929898","MRI Neurofeedback and Brain Circuits Related to Motivation in Healthy Participants","Bridging Scales to Understand Endogenous Neuromodulation and Its Regulation","Inclusion Criteria:\n\n* Age between 18 and 45 years\n* Male or female\n* Right-handed\n* In good general health\n* Women of childbearing capacity: use of effective method of birth control\n\nExclusion Criteria:\n\n* Current or diagnosis within past six months of an DSM-V Axis I or Axis II disorder (self-reported)\n* CES-D score of 20 or higher (indicating significant current depression symptoms)\n* Current or past six month use of prescription medications indicated for psychiatric conditions (e.g.,depression, anxiety)\n* Current serious medical illness (self-reported)\n* Head injury resulting in loss of consciousness\n* For participants age \\> 59 years, a total scaled score \\\u003C 8 on the Dementia Rating Scale-2.\n* A clinically-defined neurological disorder including, but not limited to:\n* Any condition likely to be associated with increased intracranial pressure\n* Space occupying brain lesion\n* History of stroke\n* Transient ischemic attack within two years\n* Cerebral aneurysm\n* Dementia\n* Mini Mental Status Exam (MMSE) score of \\\u003C24\n* Parkinson's disease\n* Huntington's disease\n* Multiple sclerosis\n* Presence of cochlear implants or other implanted electronic devices or non-removable metal (e.g., non-removable piercing, IUD)\n* History of an eye injury involving metal. Participants who worked with metal may be allowed to participate on a case-by-case basis with prior written approval from BIAC.\n* Claustrophobia or unwillingness to tolerate the confinement associated with being in the MRI scanner.\n* Weight of more than 250 pounds",{"count":336,"type":21},190,[24],"The purpose of this research study is to understand how healthy individuals self-regulate motivation by observing brain activity using magnetic resonance imaging (MRI).",[35,340,341],"Memory","Self-regulation","2025-08-21",{"date":344,"type":51},"2025-08-22",{"date":346,"type":51},"2023-07-30",{"date":348,"type":21},"2026-09-09",{"name":350,"class":89},"Duke University",{"id":352,"slug":353,"hasResults":11,"nctId":354,"briefTitle":355,"officialTitle":356,"acronym":357,"eligibilityCriteria":358,"healthyVolunteers":16,"sex":67,"minAge":4,"maxAge":4,"enrollmentInfo":359,"targetDuration":4,"studyType":22,"phases":361,"briefSummary":362,"conditions":363,"keywords":368,"overallStatus":79,"whyStopped":4,"lastUpdateSubmitDate":374,"lastUpdatePostDateStruct":375,"startDateStruct":377,"completionDateStruct":378,"leadSponsor":380,"locationsCount":122},"100596229","the-effect-of-animation-based-education-on-menopausal-womens-attitudes-behaviors-and-screening-test-participation-regarding-breast-cancer-100596229","NCT07042737","The Effect of Animation-Based Education on Menopausal Women's Attitudes, Behaviors, and Screening Test Participation Regarding Breast Cancer","The Effect of Education Provided to Women in Menopause Through Animation on Breast Cancer Attitudes, Behaviors, and Screening Test Participation","Menopause","Inclusion Criteria:\n\n* Not having been diagnosed with breast cancer,\n* not performing regular self-examinations (those who performed self-examinations at least once a month were excluded),\n* not having had a mammogram (those who had a mammogram within the first six months after training were excluded),\n* not having undergone a clinical breast examination (those who underwent a clinical breast examination within the first 6 months after the training were excluded),\n* not breastfeeding or being pregnant, being literate, owning a smartphone,\n* having internet access,\n* not having uterine abnormalities,\n* having ovaries,\n* not having used sex hormones.\n\nExclusion Criteria:\n\n* never experiencing menopausal symptoms,\n* undergoing surgical menopause,\n* currently or previously using hormonal therapy,\n* having a psychiatric disorder,\n* having menstruated in the past year,\n* incomplete forms,\n* not fully participating in video-based education programs.",{"count":360,"type":21},136,[24],"The aim of this study was to determine the effect of education provided to women in menopause through animation on their attitudes toward breast cancer, behaviors, and screening test participation. The study will include a total of 136 women in the menopausal period, comprising 68 experimental group participants and 68 control group participants who have applied to the Orduyeri and Kırtepe Family Health Centers affiliated with the Bartın Public Health Institution. Women who agree to participate in the project, which will run from January to August 2025, will receive 40-45 minute training sessions in a suitable room at the ASM. The training sessions will be conducted in groups of 8-12 people. The training content will include information about the purpose, duration, and rules of the training. After providing information about the project, a pre-test will be administered. Through face-to-face interviews, researchers assigned to the project will show animated videos enriched with sound and images via an online program they have prepared. These videos will be 10-12 minutes long, and an interim test will be conducted. Three months after the pre-test, the women participating in the study will be contacted, and a final test will be administered in their own homes. Project data will be collected using the Personal Information Form, Champion Health Belief Scale, and Breast Cancer Awareness Scale. Descriptive statistics, independent sample t-tests, chi-square tests, and repeated measures analysis of variance (ANOVA) tests will be used in the statistical analysis of the project.",[364,365,366,35,367],"Menopausal Women","Education Nursing","Breast Cancer Females","Screening Strategy",[369,370,371,372,373],"education through animation","menopause","breast cancer","screening test","motivation","2025-06-20",{"date":376,"type":51},"2025-06-29",{"date":374,"type":21},{"date":379,"type":21},"2026-10-20",{"name":381,"class":89},"Inonu University",{"id":383,"slug":384,"hasResults":11,"nctId":385,"briefTitle":386,"officialTitle":387,"acronym":4,"eligibilityCriteria":388,"healthyVolunteers":16,"sex":17,"minAge":68,"maxAge":4,"enrollmentInfo":389,"targetDuration":4,"studyType":22,"phases":391,"briefSummary":392,"conditions":393,"keywords":396,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":402,"lastUpdatePostDateStruct":403,"startDateStruct":405,"completionDateStruct":407,"leadSponsor":409,"locationsCount":122},"100579623","the-effect-of-motivational-interviewing-on-diabetes-self-management-and-severity-of-cyberchondria-in-individuals-with-diabetes-100579623","NCT06826703","The Effect of Motivational Interviewing on Diabetes Self-Management and Severity of Cyberchondria in Individuals With Diabetes","the Effect of Motivational Interviewing Based on Health Promotion Model on Diabetes Self-management and Cyberchondria Severity in Individuals With Diabetes","Inclusion Criteria:\n\n* Having diabetes for at least 6 months\n* Being over 18 years old\n* To have sufficient communication skills to answer verbal and written questions and fulfill instructions\n* Being literate\n* No physical, cognitive or mental impairment in answering the questions\n* Willingness to participate in research.\n\nExclusion Criteria:\n\n* Being under 18 years of age\n* Being hospitalized in inpatient treatment institutions due to DM or DM complications during the research process\n* The emergence of any health problem that prevents the person from continuing the research\n* Do not leave the study voluntarily.",{"count":390,"type":21},64,[24],"Objective: The aim of this study was to determine the effects of diabetes education given to individuals with diabetes using motivational interviewing technique based on the health promotion model on diabetes self-management and cyberchondria severity. Materials and Method: The population of the study consisted of 1000 individuals. The sample consisted of 64 individuals, 32 experimental and 32 control, who met the research criteria. The research will be conducted between 15.02.2025-15.03.2025 in Van Regional Training and Research Hospital Diabetes outpatient clinic. Data in the research; Descriptive Information Form, Diabetes Self-Management Scale (DMS), Cyberchondria Severity Scale-Short Form (CSS-SF) scales will be applied. Research experiment Motivational interviewing intervention based on the health belief model will be conducted once a week for 1 month. At the end of 1 month, both scales will be administered again to individuals in both experimental and control groups.",[394,35,395],"Type 2 Diabetes","Self-management",[397,398,399,400,401],"cyberchondria violence","health belief model","self-management","type 2 diabetes","motivational interview","2025-04-28",{"date":404,"type":51},"2025-04-30",{"date":406,"type":51},"2025-02-15",{"date":408,"type":21},"2025-08-15",{"name":410,"class":89},"Ataturk University",{"id":412,"slug":413,"hasResults":11,"nctId":414,"briefTitle":415,"officialTitle":416,"acronym":4,"eligibilityCriteria":417,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":418,"targetDuration":4,"studyType":22,"phases":420,"briefSummary":421,"conditions":422,"keywords":426,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":432,"lastUpdatePostDateStruct":433,"startDateStruct":435,"completionDateStruct":437,"leadSponsor":439,"locationsCount":122},"100587143","motivational-training-program-for-pre-service-physical-education-teachers-100587143","NCT06924554","Motivational Training Program for Pre-service Physical Education Teachers","Study Protocol of a Non-randomized Controlled Trial on a Circumplex Model-based Motivational Training Program for Pre-service Physical Education Teachers","Inclusion Criteria:\n\n* Enrollment in the Master's in Physical Education Teacher Education at the University of Zaragoza.\n* 100% attendance in training sessions (experimental group).\n* Completion of questionnaires at three time points (pre-test, intermediate, and post-test).\n* Participation in the final focus group discussion.\n\nExclusion Criteria:\n\n* Failure to complete required assessments.\n* Lack of attendance in mandatory sessions.",{"count":419,"type":21},38,[24],"This study presents the protocol for a non-randomized controlled trial evaluating a motivational-based training program for pre-service Physical Education teachers. The experimental group will participate in a 14-hour training program based on Self-Determination Theory and the circumplex model. The program consists of theoretical and practical training to foster motivating teaching styles and minimize demotivating ones. The control group will follow the standard curriculum of the Master's in Physical Education Teacher Education program without exposure to the specific intervention.",[423,35,424,425],"Teaching Styles","Competence","Pre-service Teachers",[427,428,429,430,431],"Self-Determination Theory","(de)motivating teaching styles","physical education teacher education","quasi-experimental study","mixed-methods research","2025-04-04",{"date":434,"type":51},"2025-04-11",{"date":436,"type":21},"2025-09",{"date":438,"type":21},"2026-09",{"name":440,"class":89},"Universidad de Zaragoza",{"id":442,"slug":443,"hasResults":11,"nctId":444,"briefTitle":445,"officialTitle":446,"acronym":4,"eligibilityCriteria":447,"healthyVolunteers":16,"sex":17,"minAge":68,"maxAge":448,"enrollmentInfo":449,"targetDuration":4,"studyType":22,"phases":451,"briefSummary":452,"conditions":453,"keywords":4,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":454,"lastUpdatePostDateStruct":455,"startDateStruct":457,"completionDateStruct":459,"leadSponsor":461,"locationsCount":122},"100582164","does-educatonal-escape-game-affect-students-motvaton-academc-self-effcacy-and-success-levels-a-quas-expermental-study-100582164","NCT06859749","Does educatıonal Escape Game Affect Students' motıvatıon, academıc Self-effıcacy and Success Levels: a quası-experımental Study","Does educatıonal Escape Game Affect Students' motıvatıon, academıc Self-effıcacy and Success Levels","Inclusion Criteria:\n\n* Being over 18 years of age,\n* Receiving education in an elderly care program,\n* Not having previously taken the \"Elderly Care Principles and Practices I\" and \"Elderly Care Principles and Practices II\" courses,\n* Providing attendance during data collection processes.\n* Having a phone and internet that can enter Google forms.\n\nExclusion Criteria:\n\n* Being under 18 years of age,\n* Not cooperating,\n* Having previously taken the \"Elderly Care Principles and Practices I\" and \"Elderly Care Principles and Practices II\" courses,\n* Being absent.","50 Years",{"count":450,"type":21},68,[24],"This is a semi-experimental study. The study aimed to examine the effects of an educational escape game on students' motivation, academic self-efficacy and achievement levels. Students studying in an elderly care program will be included in the study. Students will be divided into 2 groups according to their branches: experimental (educational escape game) and control (question-answer).\n\nH1. Students participating in the escape game will show significantly higher motivation in the \"Motivation Scale for Teaching Materials\" than students participating in the question-answer method.\n\nH2. Students participating in the escape game will show significantly higher self-efficacy in the \"Academic Self-Efficacy Scale\" than students participating in the question-answer method.\n\nH3. Students participating in the escape game will show significantly higher success in the \"Achievement Test\" than students participating in the question-answer method.",[35,76],"2025-03-04",{"date":456,"type":51},"2025-03-05",{"date":458,"type":51},"2024-11-01",{"date":460,"type":21},"2025-03-20",{"name":462,"class":89},"Muş Alparslan University",{"id":464,"slug":465,"hasResults":11,"nctId":466,"briefTitle":467,"officialTitle":467,"acronym":4,"eligibilityCriteria":468,"healthyVolunteers":16,"sex":17,"minAge":469,"maxAge":470,"enrollmentInfo":471,"targetDuration":4,"studyType":22,"phases":472,"briefSummary":473,"conditions":474,"keywords":4,"overallStatus":79,"whyStopped":4,"lastUpdateSubmitDate":479,"lastUpdatePostDateStruct":480,"startDateStruct":482,"completionDateStruct":484,"leadSponsor":486,"locationsCount":122},"100521556","emotion-aging-and-decision-making-100521556","NCT06071130","Emotion, Aging, and Decision Making","Inclusion Criteria:\n\n* Experiment 4A: We will follow the standard exclusion protocol used in previous Fit \\& Strong! studies (e.g., Hughes et al., 2004; 2006). The participant's physician will be contacted for clearance to participate if they have a history of high blood pressure, or experience dizziness, lightheadedness, or chest pain or pressure during physical activities (walking, climbing stairs, and household chores, etc.) (see document: \"E4\\_NeedforPhysicianScreeningQuestionnaire.docx\"). Additionally, physicians will be contacted if participants indicate that they fall, feel unsteady, or use an assistive walking or standing device. For these conditions and any special considerations that a participant may express, physicians will be contacted for clearance.\n\nExperiment 4B: Only participants who participated in Experiment 4A are eligible to participate in Experiment 4B.\n\nExclusion Criteria:\n\n* Experiment 4A: We will follow the standard exclusion protocol used in previous Fit \\& Strong! studies (e.g., Hughes et al., 2004; 2006). For instance, participants will be excluded for joint steroid injections within 3 months, knee or hip surgery within the previous 6 months or next year, rheumatoid arthritis or other systemic inflammatory arthritis, or uncontrolled diabetes. The participant's physician will be contacted for clearance to participate if they have a history of high blood pressure, or experience dizziness, lightheadedness, or chest pain or pressure during physical activities (walking, climbing stairs, and household chores, etc.) (see document: \"E4\\_NeedforPhysicianScreeningQuestionnaire.docx\"). Additionally, physicians will be contacted if participants indicate that they fall, feel unsteady, or use an assistive walking or standing device. For these conditions and any special considerations that a participant may express, physicians will be contacted for clearance (see document: \"StatementofMedicalClearanceforExercise.docx\" and \"CoverLetterforMedicalClearanceforExercise.docx\").\n\nExperiment 4B: Participants who did not participate in Experiment 4A are not eligible to participate in Experiment 4B.","65 Years","80 Years",{"count":70,"type":21},[24],"Exercise is routinely recommended because of its benefits for physical, cognitive, and mental health. It is especially beneficial for older adults due to its potential buffering effects against Alzheimer's disease and related dementias (Luck et al., 2014). However, little is known about how to best encourage older adults to exercise. Based on behavior change theory, different intrapersonal and interpersonal motivational factors are likely to be relevant during the contemplation, action, and maintenance stages of behavior change. Generally, as a result of motivational shifts toward prioritizing positivity and socially meaningful goals with advancing age (Carstensen, 2006), socioemotional aspects of decision making may become more salient and influential for older adults (Mikels et al., 2015; Peter et al., 2011). Our previous work has demonstrated that positive affect (Mikels et al., 2020) and social goals (Steltenpohl et al., 2019) play a critical role in older adults' motivation to exercise, but these two lines of research have not been integrated to date. Recent work indicates that positive affect is particularly beneficial for health when shared in social connections (Fredrickson, 2016; Major et al., 2018), and the proposed work will, for the first time, examine how shared interpersonal positivity may impact exercise decision making and behavior, especially during the contemplation and action\u002Fmaintenance stages of behavior change.\n\nBut who are the older adults that benefit the most from exercise in terms of physical, cognitive, and mental health (and should be hence be targeted with messages)? Not all older adults reap the benefits of exercise (Sparks, 2014) and, conversely, sedentary older adults have the most to gain. Overall, the current proposed research program is innovative in its (a) translational application of insights from affective, cognitive, and aging theory and research to understand the antecedents and outcomes of exercise decision making in younger and older adults, (b) conceptualization of both the social and emotional aspects of decision making, (c) development of novel methods for health messaging that incorporate social influences, and (d) novel assessments of the exercise-health link.",[35,475,476,477,478],"Aging","Health Behavior","Emotions","Social Behavior","2025-02-10",{"date":481,"type":51},"2025-02-12",{"date":483,"type":21},"2025-09-03",{"date":485,"type":21},"2027-12-31",{"name":487,"class":89},"DePaul University",{"id":489,"slug":490,"hasResults":11,"nctId":491,"briefTitle":492,"officialTitle":492,"acronym":493,"eligibilityCriteria":494,"healthyVolunteers":16,"sex":17,"minAge":68,"maxAge":495,"enrollmentInfo":496,"targetDuration":4,"studyType":131,"phases":4,"briefSummary":498,"conditions":499,"keywords":503,"overallStatus":79,"whyStopped":4,"lastUpdateSubmitDate":507,"lastUpdatePostDateStruct":508,"startDateStruct":510,"completionDateStruct":512,"leadSponsor":513,"locationsCount":122},"100576236","investigation-of-objective-cognitive-effort-in-neuropsychological-evaluation-of-psychotic-disorders-100576236","NCT06782672","Investigation of Objective Cognitive Effort in Neuropsychological Evaluation of Psychotic Disorders","INVESTIGECCO","Inclusion Criteria in both groups\n\n\\- Age ≥ 18 years and ≤60 years\n\nInclusion criteria for the psychotic disorders group:\n\n\\- Patients with a diagnosis within the schizophrenia spectrum and other psychotic disorders according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5; APA, 2015).\n\nInclusion criterion for the non-clinical group:\n\n\\- Absence of any psychiatric disorder.\n\nnon-inclusion criteria in both groups\n\n* Neurological disorder or history of head trauma;\n* Cardiovascular disease or treatment for hypertension;\n* Substance abuse or dependence disorder;\n* Individuals who cannot understand or speak French;\n* Non-affiliation with a social security system;\n* Individuals participating in another study that includes an ongoing exclusion period;\n* Individuals who have not provided written informed consent to participate in the study;\n* Pregnant or breastfeeding women;\n* Absence of written consent from the legal guardian for patients under guardianship;\n* Absence of notification to the curator for patients under curatorship.","60 Years",{"count":497,"type":21},100,"Psychotic disorders are characterised by a heterogeneity of symptoms, including cognitive disorders, which predict functional outcome. To date, the evaluation of cognitive functions essentially measures performance. Cognitive effort and the influence of psychological factors are rarely considered.\n\nBased on the principle of energy conservation, the Motivational Intensity Theory (MIT) allows to test cognitive effort independently of performance, by measuring cardiovascular reactivity, as well as controlling for psychological factors (e.g., mood, fatigue, anxiety).\n\nThe main aim of this study is to investigate in a memory task the interaction between cognitive effort, performance and psychological factors in individuals with psychotic disorders compared to a non-clinical group, based on the predictions of the MIT.\n\nThis study will provide insights into the nature of cognitive impairment in psychotic disorders: primary or secondary to motivational (effort) or psychological (mood, fatigue, anxiety) difficulties.",[500,501,502,35],"Schizophrenia","Psychotic Disorders","Cognitive Impairment",[504,505,506],"memory","effort","cardiovascular reactivity","2025-01-17",{"date":509,"type":51},"2025-01-20",{"date":511,"type":21},"2025-01-27",{"date":84,"type":21},{"name":514,"class":89},"University Hospital, Montpellier",{"id":516,"slug":517,"hasResults":11,"nctId":518,"briefTitle":519,"officialTitle":520,"acronym":4,"eligibilityCriteria":521,"healthyVolunteers":16,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":522,"targetDuration":4,"studyType":22,"phases":524,"briefSummary":525,"conditions":526,"keywords":531,"overallStatus":79,"whyStopped":4,"lastUpdateSubmitDate":533,"lastUpdatePostDateStruct":534,"startDateStruct":536,"completionDateStruct":538,"leadSponsor":540,"locationsCount":4},"100526677","physical-literacy-based-intervention-for-older-adults-100526677","NCT06137859","Physical Literacy-based Intervention for Older Adults","Physical Literacy-based Intervention (PLBI) for Older Adults: A Cluster Randomized Controlled Trial Study Protocol","Inclusion Criteria:\n\n* those aged 65 to 74 years old who are registered in a daycare center\u002Funit for the elderly in Hong Kong.\n* the ability to walk eight meters without assistance.\n* able to read and write.\n\nExclusion Criteria:\n\n* neurological disease which impairs mobility, cardiovascular disease which results in shortness of breath or angina on walking up one flight of stairs.\n* cognitive impairment. Participants' cognitive function will be screened by the Chinese Mini-Mental State Examination and those who score below 24 will be excluded.",{"count":523,"type":21},400,[24],"The ageing population creates concerns and challenges worldwide. The large number of older adults (aged over 65) in Hong Kong continues to rise as people live longer. This may result in heavy burdens on public services and problems such as a shortage of medical resources.\n\nThe purpose of this study is to implement a physical literacy-based intervention (PLBI) among older adults in Hong Kong in order to achieve the goal of health promotion. A two-arm cluster randomized controlled trial will be employed in this proposed study. Ten daycare centers for the elderly in Hong Kong will be invited to participate in this study. The intervention group will receive functional fitness training and mastering physical literacy class twice a week with buddy peer support, and they will be asked to keep a reflective writing journal on a daily basis for 12 weeks in total. Participants will be evaluated at baseline (week 0), post-intervention (week 12), and at 6-week follow-up (week 18). This will consist of objective and self-reported measures covering elements within physical literacy (i.e. physical competence, motivation and confidence, knowledge and understanding) and also physical activity levels on an individual basis.\n\nThe study intends to introduce a conceptual framework of physical literacy for the elderly through an intervention that allows older people to develop daily behaviour habits, which should promote active ageing for the elderly and greater self-esteem in later life. After this study, participants may share their positive experiences, and encourage their peers in the community to become physically literate in the future. In the long run, due to the feasibility and sustainability of these potential programs, this proposed study has the potential to connect seniors through social engagement and contribute to healthy living.",[424,527,528,35,529,530],"Physical Activity","Knowledge, Attitudes, Practice","Confidence, Self","Peer Group",[532],"Physical literacy","2024-08-24",{"date":535,"type":51},"2024-08-28",{"date":537,"type":21},"2025-01-01",{"date":539,"type":21},"2025-12-31",{"name":541,"class":89},"Chinese University of Hong Kong",{"id":543,"slug":544,"hasResults":11,"nctId":545,"briefTitle":546,"officialTitle":547,"acronym":548,"eligibilityCriteria":549,"healthyVolunteers":11,"sex":17,"minAge":550,"maxAge":551,"enrollmentInfo":552,"targetDuration":4,"studyType":22,"phases":553,"briefSummary":554,"conditions":555,"keywords":557,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":561,"lastUpdatePostDateStruct":562,"startDateStruct":564,"completionDateStruct":566,"leadSponsor":568,"locationsCount":570},"100486013","animal-assisted-trauma-focused-therapy-for-children-and-adolescents-100486013","NCT05608551","Animal-assisted Trauma-focused Therapy for Children and Adolescents","Effects of a Psychotherapy Group Program for Children and Adolescents With Post-traumatic Stress Symptoms","AA TF-CBT","Inclusion Criteria:\n\n* Age between 9 and 17 years\n* experienced a traumatic event\n* remembers at least one traumatic event\n* Suffering from posttraumatic stress symptoms (screened via the CATS-2; cut-off ≥ 21; cut-off must be reached by either participant or caregiver)\n* Basic knowledge of child and parents in German to be able to understand content of the session and to fill in questionnaires\n* Informed consent (given by legal guardian for participants younger than 14 years)\n* Positive or neutral attitude towards animals\n\nExclusion Criteria:\n\n* Inability to complete questionnaires due to lack of language skills or cognitive impairment\n* Diagnosed autism spectrum disorder; Exclusion only if interaction with others and group ability is limited due to autism\n* Reported significant impairment or safety issue (e.g., active suicidal ideation, acute psychosis)\n* Known abuse of substances used for emotion regulation (e.g. cannabis, alcohol, other hard drugs)\n* Fear of domestic animals\n* Allergic reactions to domestic animals\n* Reported aggressive behavior towards animals in the past","9 Years","17 Years",{"count":315,"type":21},[24],"The study aims to investigate how the inclusion of an animal into a trauma-focused group therapy program (TF-CBT) affects therapy motivation of children and adolescents suffering from post-traumatic stress. 80 children and adolescents aged 9 to 17 years are recruited for the study. Participants must have experienced at least one traumatic event leading to post-traumatic stress symptoms. Participants are randomly allocated to one of two groups: animal-assisted trauma-focused therapy (AA TF-CBT) or standard trauma-focused therapy (TF-CBT). Parallel to the groups the parents\u002Fguardians of the participating children and adolescents take part in three parent meetings.\n\nThe results of the study help to gain insights into how the inclusion of animals in trauma-focused psychotherapy can contribute to children and adolescents attending therapy, being more motivated in therapy, and can successfully complete therapy.",[35,556],"Alliance, Therapeutic",[558,559,560,373],"PTSD","animal-assisted therapy","trauma-focused therapy","2024-07-17",{"date":563,"type":51},"2024-07-19",{"date":565,"type":51},"2022-10-01",{"date":567,"type":21},"2028-07-31",{"name":569,"class":89},"University of Basel",2,{"id":572,"slug":573,"hasResults":11,"nctId":574,"briefTitle":575,"officialTitle":576,"acronym":577,"eligibilityCriteria":578,"healthyVolunteers":11,"sex":17,"minAge":550,"maxAge":551,"enrollmentInfo":579,"targetDuration":4,"studyType":22,"phases":581,"briefSummary":582,"conditions":583,"keywords":4,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":561,"lastUpdatePostDateStruct":584,"startDateStruct":586,"completionDateStruct":588,"leadSponsor":590,"locationsCount":122},"100468824","canine-assisted-psychotherapy-motivation-alliance-100468824","NCT05384808","Canine-assisted Psychotherapy Motivation Alliance","Effects of the Inclusion of a Dog in Psychotherapy on Children's Alliance and Treatment Motivation","CAP","Inclusion Criteria for children and adolescents: :\n\n* Age between 9 and 17 years\n* Children are seeing the therapist for the first time\n* Basic knowledge of child and parents in either German or English to be able to fill in questionnaires\n* Informed consent given by legal guardian\n* Positive or neutral attitude towards dogs\n\nExclusion Criteria for children and adolescents: :\n\n* acute psychosis; early childhood autism\n* diagnosed developmental disorder or intellectual delay; if not diagnosed, exclusion when questionnaires cannot be completed due to development level\n* fear of dogs\n* allergic reactions to dogs\n* reported aggressive behavior towards animals in the past\n\nInclusion criteria for therapists:\n\n* working with an own therapy dog\n* completed therapy training or if not completed far advanced therapy training under supervision\n* working with children and adolescents aged 9 to 17 years\n\nExclusion criteria for therapists:\n\n* not working with an own therapy dog\n* no completed or far advanced therapy training\n* not working with children and adolescents aged 9 to 17 years",{"count":580,"type":21},150,[24],"The aim of the study is to investigate the needed extent and the way a dog is integrated into psychotherapeutic interventions for them to be motivating and alliance building for children and adolescents with psychiatric disorders aged 9 to 17 years old. Specifically, we want to elaborate if the dog needs to be integrated into the therapy in a form that it is part of the therapeutic context or if the presence of the dog without being part of the therapeutic context per se is beneficial.",[35,556],{"date":585,"type":51},"2024-07-18",{"date":587,"type":51},"2022-06-01",{"date":589,"type":21},"2028-12-31",{"name":569,"class":89},{"id":592,"slug":593,"hasResults":11,"nctId":594,"briefTitle":595,"officialTitle":596,"acronym":4,"eligibilityCriteria":597,"healthyVolunteers":16,"sex":67,"minAge":68,"maxAge":495,"enrollmentInfo":598,"targetDuration":600,"studyType":131,"phases":4,"briefSummary":601,"conditions":602,"keywords":4,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":603,"lastUpdatePostDateStruct":604,"startDateStruct":606,"completionDateStruct":608,"leadSponsor":610,"locationsCount":122},"100542576","motivational-interviewing-inadequate-milk-and-cortisol-100542576","NCT06344663","Motivational Interviewing Inadequate Milk and Cortisol","The Effect of Motivational Interviews to Mothers With Insufficient Milk Perception on Breastfeeding Motivation and Cortisol Level","Inclusion Criteria:\n\n* Those aged 18 and over\n* Those who feed their babies only with breast milk\n* Do you believe that you produce enough milk to feed your baby?\" in the Insufficient Milk Perception Scale. Those who answered \"No\" to the question\n* Having given birth at 37\\>gestational weeks\n* Having a baby weighing at least 2500 grams\n* Giving birth vaginally\n* Primiparous\n\nExclusion Criteria:\n\n* Cannot speak Turkish\n* Mothers who did not agree to participate in the research",{"count":599,"type":21},130,"4 Weeks","Motivational interviewing is a technique used in many fields. No study has been found in national and international databases investigating the effect of motivational interviewing on the perception of insufficient milk, breastfeeding motivation and cortisol level. The study aimed to evaluate the effect of motivational interviews on the perception of insufficient milk, breastfeeding motivation and cortisol level.",[35],"2024-07-07",{"date":605,"type":51},"2024-07-09",{"date":607,"type":51},"2024-03-25",{"date":609,"type":21},"2024-12-25",{"name":611,"class":89},"Kahramanmaras Sutcu Imam University",{"id":613,"slug":614,"hasResults":11,"nctId":615,"briefTitle":616,"officialTitle":617,"acronym":4,"eligibilityCriteria":618,"healthyVolunteers":11,"sex":619,"minAge":620,"maxAge":621,"enrollmentInfo":622,"targetDuration":624,"studyType":131,"phases":4,"briefSummary":625,"conditions":626,"keywords":627,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":633,"lastUpdatePostDateStruct":634,"startDateStruct":636,"completionDateStruct":638,"leadSponsor":640,"locationsCount":122},"100552520","motiv8---treatment-motivation-in-forensic-youth-treatment-100552520","NCT06474156","MOTIV8 - Treatment Motivation in Forensic Youth Treatment","Motiv8: Examining Treatment Motivation Among Youth and Parents in Forensic Treatment","Inclusion Criteria:\n\n\\- entering residential MDFT\n\nExclusion Criteria:\n\n\\- (only for short term residents) residing more than an hours' drive from the juvenile justice center after detention","MALE","12 Years","24 Years",{"count":623,"type":21},16,"9 Months","This project entails to gain a deeper understanding of the development of treatment motivation over the course of intramural and outpatient forensic youth care. Research questions are 1) How does treatment motivation of youth and parents develop over the course of forensic systemic therapy, and following the transition from inpatient to outpatient therapy?; 2) Which client factors, interpersonal factors, and contextual characteristics moderate the development of treatment motivation?; 3) Which mechanisms play a role in the development of treatment motivation?; and 4) How does treatment motivation affect treatment retention and the achievement of primary therapy goals?",[35],[628,629,630,631,632],"Treatment Motivation","Multidimensional Family Therapy","Youth","Parents","Delinquency","2024-06-19",{"date":635,"type":51},"2024-06-25",{"date":637,"type":51},"2024-03-05",{"date":639,"type":21},"2025-10",{"name":641,"class":89},"University of Amsterdam"]