[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"motor-development\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:motor-development":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,44,73,103],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100617942","quantifying-motor-network-dynamics-to-predict-and-enhance-outcomes-in-pediatric-dystonia-100617942",false,"NCT07325175","Quantifying Motor Network Dynamics to Predict and Enhance Outcomes in Pediatric Dystonia","Inclusion Criteria:\n\n* For dystonia subjects:\n* Dx of dystonia (with and without DBS)\n* willingness and ability to complete study protocols.\n* For Typically Developing Controls:\n* normal developmental milestones\n* absence of any neuropsychiatric disorder\n* no significant medical condition.\n\nExclusion Criteria:\n\n* history of epilepsy\n* presence of implanted medical devices (except DBS in dystonia subjects)\n* lack of cognitive or physical ability to complete study protocol.",true,"ALL","6 Years","21 Years",{"count":20,"type":21},75,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this study is to understand the development and progression of childhood dystonia, a movement disorder, in children. The main questions it aims to answer are:\n\nHow does the activity of the neural network evolve in children with dystonia in the context of motor development? What are the effects of chronic and active stimulation on cortical and subcortical motor network function in children with deep brain stimulation (DBS)?\n\nParticipants will:\n\n* Undergo noninvasive electrophysiological measurements (EEG, EMG) to quantify neural network activity. They will be tested at rest and during a simple motor reaction task.\n* Children with DBS will be assessed in the on and off DBS state to assess effects of chronic and active changes in motor network function.",[27,28,29,30],"Dystonia","Pediatric","Deep Brain Stimulation","Motor Development","RECRUITING","2026-06-15",{"date":34,"type":35},"2026-06-16","ACTUAL",{"date":37,"type":35},"2024-01-01",{"date":39,"type":21},"2029-12-31",{"name":41,"class":42},"Children's Hospital Medical Center, Cincinnati","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":55,"phases":4,"briefSummary":56,"conditions":57,"keywords":60,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":72},"100590676","wearable-sensors-to-detect-atypical-muscle-activation-in-young-infants-100590676","NCT06970522","Wearable Sensors to Detect Atypical Muscle Activation in Young Infants","Early Detection of Atypical Neuromuscular Development Using Wearable Sensors and Video: A Comparative Analysis of Muscle and Motion","Inclusion Criteria:\n\n* For Infants with low tone:\n* Hospitalized in the NICU\n* AND \\>38 weeks post-menstrual age\n* AND abnormal normal brain imaging OR Apgar score \\\u003C7 at five minutes with umbilical cord pH (if obtained) \\\u003C7.15\n* AND 2 or more warning signs for muscle tone or posture using the HNNE short form\n* AND legal guardian able and willing to give written consent and comply with study procedures\n* For Infants with typical tone:\n* Born at 38-41 weeks of gestation\n* AND hospitalized after birth in the NICU OR well newborn nursery\n* AND infants with appropriate for gestational age birth weight\n* AND HNNE exam (short proforma) normal with no warning signs for any parameter\n* AND legal guardian able and willing to give written consent and comply with study procedures.\n\nExclusion Criteria:\n\n* Infants of Both Low Tone and Typical Tone Cohorts:\n* Missing or incomplete limbs (such as from amputation or congenital limb defects).\n* Open wounds or skin breakdown on the limbs or torso.\n* Presence of known genetic syndrome or congenital anomalies requiring surgery or affecting function\n* Use of sedative medications (may include phenobarbital if level stable and therapeutic)\n* Legal guardian unable to give written consent and comply with study procedures.\n* Does not receive medical clearance from a physician to participate in the study if the individual is receiving inpatient care.","0 Months","8 Weeks",{"count":54,"type":21},40,"OBSERVATIONAL","The purpose of this study is to see if wearable sensor technology can be used to evaluate muscle activity and\u002For identify atypical muscle tone in infants up to 48 weeks postmenstrual age (8 weeks corrected age). These sensors are placed on the surface of the skin and record data about a child's body movements and muscle activity.",[58,30,59],"Neuromuscular Disorders","Muscle Tone",[61,62],"Early Detection","Wearable Sensors","2026-03-24",{"date":65,"type":35},"2026-03-25",{"date":67,"type":35},"2025-06-25",{"date":69,"type":21},"2026-12-31",{"name":71,"class":42},"Shirley Ryan AbilityLab",2,{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":77,"acronym":4,"eligibilityCriteria":78,"healthyVolunteers":15,"sex":16,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":4,"studyType":55,"phases":4,"briefSummary":83,"conditions":84,"keywords":88,"overallStatus":93,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":97,"completionDateStruct":98,"leadSponsor":100,"locationsCount":102},"100597859","are-developmentally-at-risky-babies-environmentally-disadvantaged-100597859","NCT07063966","Are Developmentally At Risky Babies Environmentally Disadvantaged?","Inclusion Criteria:\n\nInclusion Criteria (Developmentally At-Risk Infants):\n\nInfants classified as developmentally at risk\n\nAged between 7 and 18 months\n\nParental consent for participation in the study\n\nInclusion Criteria (Typically Developing Infants):\n\nAged between 7 and 18 months\n\nParental consent for participation in the study\n\nExclusion Criteria:\n\n* Infants with unstable vital signs\n\nInfants currently hospitalized","7 Months","18 Months",{"count":82,"type":21},52,"A study conducted on infants aged between 3 and 11 months revealed a positive relationship between the home environment and developmental outcomes. Similarly, another study found that variability in motor and cognitive development could be better explained by environmental factors and parental knowledge and practices. It has also been shown that the opportunities provided in the home environment of preterm infants may be associated with motor development and sensory processing skills. In the literature, it is generally observed that studies evaluate either term infants or both preterm and term infants together. In the present study, however, infants at developmental risk and typically developing infants will be evaluated separately.\n\nThe aim of this study is to assess whether infants at developmental risk are disadvantaged in terms of their home environment.\n\nThe hypotheses of this study are as follows:\n\nH1-1: There is a difference in environmental arrangements between typically developing infants and those at developmental risk.\n\nH1-2: There is a relationship between home environmental arrangements and motor development.\n\nH1-3: There is a relationship between home environmental arrangements and sensory profile.",[85,30,86,87],"Risky Baby","Sensory Profiles","Environmental Conditions",[89,90,91,92],"risky baby","motor development","sensory profiles","environmental conditions","NOT_YET_RECRUITING","2025-07-03",{"date":96,"type":35},"2025-07-14",{"date":94,"type":21},{"date":99,"type":21},"2025-11-10",{"name":101,"class":42},"Abant Izzet Baysal University",3,{"id":104,"slug":105,"hasResults":11,"nctId":106,"briefTitle":107,"officialTitle":107,"acronym":108,"eligibilityCriteria":109,"healthyVolunteers":11,"sex":16,"minAge":110,"maxAge":111,"enrollmentInfo":112,"targetDuration":4,"studyType":55,"phases":4,"briefSummary":114,"conditions":115,"keywords":118,"overallStatus":93,"whyStopped":4,"lastUpdateSubmitDate":122,"lastUpdatePostDateStruct":123,"startDateStruct":125,"completionDateStruct":126,"leadSponsor":128,"locationsCount":43},"100585968","impact-of-vestibular-function-on-deaf-infants-activities-of-daily-living-100585968","NCT06909266","Impact of Vestibular Function on Deaf Infants' Activities of Daily Living","IVANS","Inclusion Criteria:\n\nGroup 1: Deaf children with confirmed vestibular impairment. Group 2: Deaf children without vestibular impairment. Group 3: Hearing children without vestibular impairment (control group).\n\nExclusion Criteria:\n\nPresence of neuromotor or orthopedic disorders. Presence of pervasive developmental disorders that could interfere with daily activity assessments.\"","1 Day","2 Years",{"count":113,"type":21},105,"This non-interventional study aims to assess the impact of vestibular impairments on the daily life activities of deaf children aged 0 to 2 years old. Three groups of participants will be included: deaf children with vestibular impairment, deaf children without vestibular impairment, and hearing children without vestibular dysfunction (control group).\n\nChildren's daily activities will be evaluated through the OT Hope 0-5 years tool, a parent-administered questionnaire designed to measure competencies in different areas: personal care, play, and social interactions. This study also includes qualitative interviews with parents to further explore how vestibular impairments affect children's daily routines.\n\nIt is hypothesized that:\n\n* Deaf children with vestibular impairments will show lower scores in daily life activities compared to the other two groups.\n* Deaf children without vestibular impairments will demonstrate scores closer to those of hearing children but may show some differences due to their hearing status.\n\nThe research is conducted at the Robert Debré Hospital, in Paris, and aims to enroll 105 children over a three-year period. The data collected will provide insights into the specific needs of children with vestibular impairments and lay the groundwork for targeted early interventions.",[116,117,30],"Vestibular Dysfunction","Hearing Loss",[119,120,121],"Deafness","vestibular disorder","occupational therapy","2025-03-27",{"date":124,"type":35},"2025-04-03",{"date":122,"type":21},{"date":127,"type":21},"2028-04-01",{"name":129,"class":42},"Assistance Publique - Hôpitaux de Paris"]