[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"motor-disorders\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:motor-disorders":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,14,0,[8,59,91,122,153,188,218,257,279,302,321,354,383,414],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":37,"overallStatus":46,"whyStopped":4,"lastUpdateSubmitDate":47,"lastUpdatePostDateStruct":48,"startDateStruct":51,"completionDateStruct":53,"leadSponsor":55,"locationsCount":58},"100453331","non-invasive-bci-controlled-assistive-devices-100453331",false,"NCT05183152","Non-invasive BCI-controlled Assistive Devices","Non-invasive Brain-computer Interfaces for Control of Assistive Devices","Inclusion Criteria:\n\n1. Able-bodied participants:\n\n   * good general health\n   * normal or corrected vision\n   * no history of neurological\u002Fpsychiatric disease\n   * ability to read and understand English (Research Personnel do not speak Spanish)\n2. Subjects with motor disabilities\n\n   * motor deficits due to: unilateral and bilateral stroke \u002F spinal cord injury \u002F motor neuron diseases (i.e. amyotrophic lateral sclerosis, spino-cerebellar ataxia, multiple sclerosis) \u002F muscular diseases (i.e. myopathy) \u002F traumatic or neurological pain \u002F movement disorders (i.e. cerebral palsy) \u002F orthopedic \u002F traumatic brain injury \u002F brain tumors\n   * normal or corrected vision\n   * ability to read and understand English\n   * ability to provide informed consent\n\nExclusion Criteria:\n\n1. Subjects with motor disabilities\n\n   * short attentional spans or cognitive deficits that prevent the subject from concentrating during the whole experimental session\n   * heavy medication affecting the central nervous system (including vigilance)\n   * concomitant serious illness (e.g., metabolic disorders)\n2. All participants\n\n   * factors hindering EEG\u002FEMG acquisition and the delivery of non-invasive electrical stimulation (e.g., skin infection, wounds, dermatitis, metal implants under electrodes)\n   * criteria identified in safety guidelines for MRI and TMS, in particular metallic implants",true,"ALL","18 Years","80 Years",{"count":21,"type":22},100,"ESTIMATED","INTERVENTIONAL",[25],"NA","Injuries affecting the central nervous system may disrupt the cortical pathways to muscles causing loss of motor control. Nevertheless, the brain still exhibits sensorimotor rhythms (SMRs) during movement intents or motor imagery (MI), which is the mental rehearsal of the kinesthetics of a movement without actually performing it. Brain-computer interfaces (BCIs) can decode SMRs to control assistive devices and promote functional recovery. Despite rapid advancements in non-invasive BCI systems based on EEG, two persistent challenges remain: First, the instability of SMR patterns due to the non-stationarity of neural signals, which may significantly degrade BCI performance over days and hamper the effectiveness of BCI-based rehabilitation. Second, differentiating MI patterns corresponding to fine hand movements of the same limb is still difficult due to the low spatial resolution of EEG. To address the first challenge, subjects usually learn to elicit reliable SMR and improve BCI control through longitudinal training, so a fundamental question is how to accelerate subject training building upon the SMR neurophysiology. In this study, the investigators hypothesize that conditioning the brain with transcutaneous electrical spinal stimulation, which reportedly induces cortical inhibition, would constrain the neural dynamics and promote focal and strong SMR modulations in subsequent MI-based BCI training sessions - leading to accelerated BCI training. To address the second challenge, the investigators hypothesize that neuromuscular electrical stimulation (NMES) applied contingent to the voluntary activation of the primary motor cortex through MI can help differentiate patterns of activity associated with different hand movements of the same limb by consistently recruiting the separate neural pathways associated with each of the movements within a closed-loop BCI setup. The investigators study the neuroplastic changes associated with training with the two stimulation modalities.",[28,29,30,31,32,33,34,35,36],"Motor Disorders","Healthy","Spinal Cord Injuries","Muscular Diseases","Motor Neuron Disease","Stroke","Traumatic Brain Injury","Movement Disorders","Multiple Sclerosis",[38,39,40,41,42,43,44,45],"motor deficits","able-bodied, healthy","unilateral and bilateral stroke","spinal cord injury","motor neuron diseases","muscular diseases (i.e. myopathy)","traumatic or neurological pain","movement disorders","RECRUITING","2026-04-27",{"date":49,"type":50},"2026-05-01","ACTUAL",{"date":52,"type":50},"2021-06-16",{"date":54,"type":22},"2028-12-30",{"name":56,"class":57},"University of Texas at Austin","OTHER",1,{"id":60,"slug":61,"hasResults":11,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":65,"eligibilityCriteria":66,"healthyVolunteers":16,"sex":17,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":4,"studyType":23,"phases":71,"briefSummary":72,"conditions":73,"keywords":77,"overallStatus":46,"whyStopped":4,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":58},"100497865","neuromodulation-and-neuroimaging-in-older-children-with-mild-traumatic-brain-injury-100497865","NCT05762796","Neuromodulation and Neuroimaging in Older Children With Mild Traumatic Brain Injury","Assessing the Efficacy of Alterations in Subcortical-Cortical Functional Connectivity From Transcranial Direct Current Stimulation in Older Children After Mild Traumatic Brain Injury","CI-tDCS","Experimental Cohort:\n\nInclusion Criteria:\n\n* age 10-15 years at enrollment\n* enrolled after 6 weeks of mTBI injury\n* exhibiting post-concussive symptoms (e.g., difficulty planning, sequencing, and executing a motor action)\n* Sustained an mTBI or concussion within the past 12 months\n* Parent and child proficient in English\n\nHealthy Controls Cohort:\n\nInclusion Criteria:\n\n* 10 to 15 years old\n* no concussion history\n* Parent and child proficient in English\n\nExperimental Cohort:\n\nExclusion Criteria:\n\n* loss of consciousness \\> 30 minutes\n* post-traumatic amnesia \\> 24 hours\n* intracranial findings on clinical imaging\n* history of developmental delay\n* history of learning disability or ADHD\n* Sustained a lower limb or upper limb injury that has not healed\n* History of Seizures\n* Noticeable skin lesions\u002Fburns or any other severe skin problems at the site of the electrodes before the start of the stimulation.\n* Parent\u002Fguardian report metal implants anywhere in the head\u002Fncek\u002Fbody on the MRI screening form (see attached).\n* Parent\u002Fguardian report shrapnel\u002Fbullets in the body on the MRI screening form.\n* Parent\u002Fguardian report any electronic implant such as a cardiac pacemaker, cochlear implant, ventricular shunt, cardiac defibrillator, aneurysm clips, pacing wires, any implant held in place with a magnet, heart valve, or deep brain stimulator on the MRI screening form.\n* Parent\u002Fguardian report a craniotomy or any other surgery in the past 6 weeks on the MRI screening form.\n* Parent\u002Fguardian report being claustrophobic on the MRI screening form.\n* Parent\u002Fguardian report and provide orbit x-ray after the eye injury involving a metal that the subject is cleared as indicated on the MRI screening form.\n* Pregnant females as reported by parent\u002Fguardian on the pre-consent screening form. Pubertal\u002Fpost-pubertal female participants14 and above will be provided a separate post-consent screening form at each MRI visit to ensure the female reports accurately without fear.\n\nHealthy Controls Cohort:\n\nExclusion Criteria:\n\n* diagnosed with developmental delay\n* sustained a lower limb or upper limb injury that has not healed\n* history of Learning Disability and\u002For ADHD\n* Parent\u002Fguardian report metal implants anywhere in the head\u002Fncek\u002Fbody on the MRI screening form (see attached).\n* Parent\u002Fguardian report shrapnel\u002Fbullets in the body on the MRI screening form.\n* Parent\u002Fguardian report any electronic implant such as a cardiac pacemaker, cochlear implant, ventricular shunt, cardiac defibrillator, aneurysm clips, pacing wires, any implant held in place with a magnet, heart valve, or deep brain stimulator on the MRI screening form.\n* Parent\u002Fguardian report a craniotomy or any other surgery in the past 6 weeks on the MRI screening form.\n* Parent\u002Fguardian report being claustrophobic on the MRI screening form.\n* Parent\u002Fguardian report and provide orbit x-ray after the eye injury involving a metal that the subject is cleared as indicated on the MRI screening form.\n* Pregnant females as reported by parent\u002Fguardian on the pre-consent screening form. Post-pubertal females 14 and above will be provided a separate post-consent screening form at each MRI visit to ensure the female reports accurately without fear.","10 Years","15 Years",{"count":70,"type":22},10,[25],"Mild traumatic brain injury (mTBI) often causes persistent motor and cognitive deficits in children resulting in functional limitations. We are testing a brain stimulation method along with evaluating objective tools to help record and restore communication among affected brain areas, which will facilitate recovery in youth after mTBI.",[74,75,28,76],"Brain Concussion","Mild Traumatic Brain Injury","Cognitive Impairment",[74,75,78,79,76,80,81],"Child","Motor Activity","Transcranial Direct Current Stimulation","Neuroimaging","2026-02-02",{"date":84,"type":50},"2026-02-03",{"date":86,"type":50},"2024-02-20",{"date":88,"type":22},"2027-06",{"name":90,"class":57},"State University of New York at Buffalo",{"id":92,"slug":93,"hasResults":11,"nctId":94,"briefTitle":95,"officialTitle":96,"acronym":4,"eligibilityCriteria":97,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":98,"enrollmentInfo":99,"targetDuration":4,"studyType":23,"phases":101,"briefSummary":102,"conditions":103,"keywords":107,"overallStatus":112,"whyStopped":4,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":116,"completionDateStruct":118,"leadSponsor":120,"locationsCount":58},"100609160","scalp-acupuncture-combined-with-rtms-for-upper-limb-motor-dysfunction-in-stroke-a-brain-network-study-100609160","NCT07210944","Scalp Acupuncture Combined With rTMS for Upper Limb Motor Dysfunction in Stroke: A Brain Network Study","Research Protocol for a Randomized Controlled Trial on Brain Network Study of Upper Limb Motor Dysfunction in Stroke Patients Treated With Scalp Acupuncture Combined With rTMS","Inclusion Criteria:\n\n* Meet the diagnostic criteria for stroke (symptoms and signs, imaging indicators, etc.), and are independently diagnosed by two deputy chief physicians\n* Age 18-70 years old, first episode, duration 1-6 months\n* The diagnostic criteria for upper limb dysfunction align with the Brunnstrom staging system: patients in Brunnstrom stages II to IV. Stage II: patients exhibit associative responses and can perform coordinated movements, with minimal voluntary movements; Stage III: patients show voluntary coordinated movements, such as grasping with the hand but not extending; Stage IV: patients can perform isolated movements, such as pinching with the hand and limited extension\n* No severe visual or hearing impairment, able to cooperate with relevant assessments and tests\n* The score of the Mini-Mental State Examination is ≥20 points\n* Vital signs are stable, with no signs of progressive neurological symptoms\n* The patient or legal guardian agrees and signs the informed consent form\n\nExclusion Criteria:\n\n* Severe visual impairment, hemispatial neglect, body image disorder\n* Individuals who cannot undergo rTMS treatment due to reasons such as metal implants, cardiac pacemakers, or skull defects\n* Previous history of brain tumor, brain trauma, epilepsy, and risk of epileptic seizures\n* Any other factors that affect assessment and treatment\n* Dysfunction of limb movement caused by other reasons (such as trauma, etc.)","70 Years",{"count":100,"type":22},44,[25],"This study aims to compare the improvement effects of the rTMS (repetitive transcranial magnetic stimulation) combined with conventional rehabilitation therapy group with the rTMS combined with scalp acupuncture and conventional rehabilitation therapy group. Through statistical analysis of the results obtained from functional near-infrared spectroscopy technology during task states, the investigators elucidate the neuroregulatory mechanism of scalp acupuncture combined with rTMS in improving upper limb motor function in stroke patients under MEP localization, and provide evidence for a more optimal rehabilitation program for post-stroke upper limb motor dysfunction.",[104,105,33,106,28],"Upper Extremity","Acupuncture Therapy","Transcranial Magnetic Stimulation Repetitive",[108,109,110,111,28],"Conventional rehabilitation therapy","Scalp Acupuncture","Upper Limb","Repetitive Transcranial Magnetic Stimulation","NOT_YET_RECRUITING","2025-11-18",{"date":115,"type":50},"2025-11-19",{"date":117,"type":22},"2025-12-05",{"date":119,"type":22},"2027-05-30",{"name":121,"class":57},"Debiao Kong",{"id":123,"slug":124,"hasResults":11,"nctId":125,"briefTitle":126,"officialTitle":126,"acronym":127,"eligibilityCriteria":128,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":129,"targetDuration":131,"studyType":132,"phases":4,"briefSummary":133,"conditions":134,"keywords":138,"overallStatus":46,"whyStopped":4,"lastUpdateSubmitDate":144,"lastUpdatePostDateStruct":145,"startDateStruct":147,"completionDateStruct":149,"leadSponsor":151,"locationsCount":58},"100558107","outcomes-of-ict-assistive-technology-in-rehabilitation-pathways-100558107","NCT06546813","Outcomes of ICT Assistive Technology in RehabiliTAtIoN Pathways","ATTAIN","consecutive enrollment of subjects falling within\n\nInclusion Criteria:\n\n* patients in need of prosthetic interventions for Augmentative Alternative Communication, computer accessibility, and environmental control\n* patients who agree to participate in the study\n\nExclusion Criteria:\n\n* none",{"count":130,"type":22},50,"6 Months","OBSERVATIONAL","The study aims to improve the quality of prosthetic intervention and verify the adequacy of assistive devices, and measurement outcomes. Fifty patients in need of prosthetic interventions for Augmentative Alternative Communication, computer accessibility, and environmental control will be recruited within the DAT Unit of the Fondazione Don Carlo Gnocchi \"IRCCS S.Maria Nascente\" in Milan. At baseline (T0) a physician and a psychologist will perform a clinical evaluation and the AT outcome assessment. The participants will be contacted for the follow-up phase (T1) 3 to 6 months after having received the assistive solution. At T1 clinicians will readminister the AT outcome assessment. In order to make the assessment accessible to all participants, these tests and questionnaires will be administered on Windows PCs, using Grid3 software, or on a specifically created accessible web page.",[135,136,28,137],"Communication Aids for Disabled","Communication Disorders","Cognitive Disorder",[139,140,141,142,143],"ICT AT","AAC AT","AAL AT","Assistive Technology","Outcome Assessment","2025-08-25",{"date":146,"type":50},"2025-08-26",{"date":148,"type":50},"2023-06-01",{"date":150,"type":22},"2025-10-31",{"name":152,"class":57},"Fondazione Don Carlo Gnocchi Onlus",{"id":154,"slug":155,"hasResults":11,"nctId":156,"briefTitle":157,"officialTitle":158,"acronym":159,"eligibilityCriteria":160,"healthyVolunteers":11,"sex":17,"minAge":161,"maxAge":162,"enrollmentInfo":163,"targetDuration":4,"studyType":23,"phases":165,"briefSummary":166,"conditions":167,"keywords":169,"overallStatus":46,"whyStopped":4,"lastUpdateSubmitDate":179,"lastUpdatePostDateStruct":180,"startDateStruct":182,"completionDateStruct":184,"leadSponsor":186,"locationsCount":58},"100600251","electroencephalogram-in-patients-with-friedreichs-ataxia-for-the-study-of-the-structural-and-functional-connectome-100600251","NCT07095062","Electroencephalogram in Patients With Friedreich's Ataxia for the Study of the Structural and Functional Connectome.","Structural-Functional Connectome and High Density Electroencephalogram: Pilot Study in Patients With Friedreich's Ataxia.","CONNETTOMA","Inclusion criteria:\n\n* age between 8 and 60 years;\n* genetic diagnosis of FRDA: presence of guanine-adenine trinucleotide (GAA) expansion in the two alleles of the fratassin gene, GAA1 and GAA2;\n* score on the Scale for the Assessment and Rating of Ataxia (SARA) \\\u003C 30;\n* ability to take part in a neuropsychological assessment in Italian.\n\nExclusion criteria:\n\n* age different from the range 8-60 years;\n* diagnosis of acquired ataxia or other genetic ataxias;\n* SARA scale score ≥ 30;\n* inability to take part in an Italian-language neuropsychological assessment","8 Years","60 Years",{"count":164,"type":22},30,[25],"Prospective, exploratory, multicenter pilot study investigating the structural and functional connectome in patients with Friedreich's Ataxia (FRDA) using high-density electroencephalogram (HD-EEG). The aim is to identify neurophysiological biomarkers and analyze the relationship between cortical connectivity, cognitive functioning, and clinical severity, particularly in response to rehabilitation treatment.",[168,28],"Friedreich's Ataxia",[170,171,172,173,174,175,176,177,178],"Functional Connectivity","HD-EEG","FRDA","Connectome","Cognitive Functioning","Neurodegenerative Disease","Cerebellar Disorders","Neurophysiological Biomarkers","Friedreich Ataxia","2025-07-23",{"date":181,"type":50},"2025-07-31",{"date":183,"type":50},"2025-07-07",{"date":185,"type":22},"2026-12-31",{"name":187,"class":57},"IRCCS Eugenio Medea",{"id":189,"slug":190,"hasResults":11,"nctId":191,"briefTitle":192,"officialTitle":193,"acronym":194,"eligibilityCriteria":195,"healthyVolunteers":16,"sex":17,"minAge":196,"maxAge":197,"enrollmentInfo":198,"targetDuration":4,"studyType":132,"phases":4,"briefSummary":200,"conditions":201,"keywords":205,"overallStatus":46,"whyStopped":4,"lastUpdateSubmitDate":209,"lastUpdatePostDateStruct":210,"startDateStruct":212,"completionDateStruct":214,"leadSponsor":216,"locationsCount":58},"100537525","families-filming-infants-learning-movement-100537525","NCT06278961","Families Filming Infants Learning Movement","The Ontogeny of Fidgety Movements in Infants At High-Risk of Cerebral Palsy","FILM","Inclusion Criteria:\n\n* Infants born full-term with typical development, bithweight \\>2500g\n* Infants with a history of brochopulmonary dysplasia, defined as having a preterm birth (\\\u003C33 weeks gestational age) and requiring supplemental oxygen beyond 36 weeks gestational age\n* Infants with neonatal encephalopathy, who required hypothermic cooling treatment\n* Infants born \\\u003C36 weeks gestational age\n* Infants born in a multiple gestation pregnancy\n* Infants with a diagnosis of Trisomy 21\n* Infants born and diagnosed with SMA prenatally, via newborn screening assessment or prior to 10 weeks corrected age\n* Infants are less than 10 weeks corrected age at time of enrollment\n\nExclusion Criteria:\n\n* Children who are enrolled in DCFS custody\n* Parent or infant guardian does not have a smartphone","10 Weeks","20 Weeks",{"count":199,"type":22},350,"The study objective is to improve accuracy in the early detection of neurodevelopmental impairment, especially CP, by evaluating the timepoint (in weeks post term age) that the Prechtl GMA is most useful for prediction of neurodevelopmental impairment at two years of age in children with and without medical complexity. The study team plans to recruit 100 healthy, term-born infants and 250 infants at risk of developing CP for a total of 350 enrolled infants.",[202,203,28,204],"Infant Development","Cerebral Palsy","Neurological Disorder",[206,207,208],"fidgety movements","general movement assessment","cerebral palsy","2025-02-11",{"date":211,"type":50},"2025-02-13",{"date":213,"type":50},"2021-01-28",{"date":215,"type":22},"2026-09-30",{"name":217,"class":57},"Ann & Robert H Lurie Children's Hospital of Chicago",{"id":219,"slug":220,"hasResults":11,"nctId":221,"briefTitle":222,"officialTitle":223,"acronym":4,"eligibilityCriteria":224,"healthyVolunteers":11,"sex":17,"minAge":225,"maxAge":4,"enrollmentInfo":226,"targetDuration":4,"studyType":23,"phases":228,"briefSummary":229,"conditions":230,"keywords":236,"overallStatus":46,"whyStopped":4,"lastUpdateSubmitDate":247,"lastUpdatePostDateStruct":248,"startDateStruct":250,"completionDateStruct":252,"leadSponsor":254,"locationsCount":256},"100522771","paiact---an-artificial-intelligence-driven-chatbot-assisted-act-100522771","NCT06086951","Pai.ACT - An Artificial Intelligence Driven Chatbot Assisted ACT","Pai.ACT: A Deep-learning-powered, Smartphone-delivered, Acceptance and Commitment Therapy for Parents of Children With Special Needs: A Feasibility Study","Inclusion Criteria:\n\n* Primary caregivers who are Cantonese-speaking Hong Kong residents.\n* The caregiver must cohabitate with the child with special needs.\n* The child under the participant's care should be aged between 2-8 years. The child should be either diagnosed or suspected to have one of the developmental conditions such as ASD, ADHD, or DD. These conditions must be recognised by the Child Assessment Service of the Department of Health and conform to the DSM-5 criteria. The diagnosis or suspected diagnosis should be documented in the electronic medical record at the study hospital or the case profile record at the collaborating non-governmental organisations.\n\nNote: The age range of 2-8 years was selected due to the substantial impact of parenting on the developmental milestones of preschoolers and junior school-aged children.\n\nExclusion Criteria:\n\n* Parents diagnosed with severe mental illnesses are excluded.\n* Parents who are currently pregnant are excluded.\n* Parents who are less than six months postpartum are excluded.\n* Parents with a developmental disability that interferes with their ability to comprehend the program's content are excluded.\n* Parents with cognitive, language, communication, visual, or hearing impairments or disorders that could impede their understanding of the intervention content are excluded.\n* Parents currently participating in other psychosocial, psychoeducational, or parenting interventions are excluded.","19 Years",{"count":227,"type":22},60,[25],"Limited psychological support for parents of children with special needs in Hong Kong can profoundly impact the child rehabilitation process and the well-being of parent-child dyads. Leveraging previous evidence from our team's research, we have developed Pai.ACT, the first deep learning-based mental health advisory system for parents. Pai.ACT incorporates the counselling logic of Acceptance and Commitment Therapy (ACT) through natural language processing, enabling parents to engage in human-like voice-to-text conversations and receive assessments and stepped-care mental health interventions, including guided self-help materials and real-time, individual-based counselling based on ACT. Following the research and development phases, we aim to kick off the utilisation of Pai.ACT by (1) pilot-testing its feasibility, acceptability, and potential efficacy in improving mental health outcomes for parents of children with special needs and (2) researching to determine the most optimal service model for parents by exploring their perceptions through focus group interviews. Pai.ACT offers accessible and comprehensive mental health services to all Chinese-speaking parents, addressing their psychological burden in caring for children with special needs. Pai.ACT could bring substantial and enduring societal benefits to Chinese-speaking families by integrating mental health support services for family caregivers with current child rehabilitation services and non-governmental organisations. Furthermore, this could contribute to reducing the public stigma attached to special needs children while increasing mental health awareness.",[231,232,233,234,235,136,28],"Autism Spectrum Disorder","Attention Deficit Hyperactivity Disorder","Neurodevelopmental Disorders","Intellectual Disability","Specific Learning Disorder",[237,238,239,240,241,242,243,244,245,246],"Deep learning","Smartphone-delivered Therapy","Acceptance and Commitment Therapy","Parents","Children with Special Needs","Feasibility trial","Parental Support","Artificial Intelligence in Healthcare","Psychological Interventions","Parenting Stress","2025-01-21",{"date":249,"type":50},"2025-01-23",{"date":251,"type":50},"2023-10-01",{"date":253,"type":22},"2025-06-30",{"name":255,"class":57},"Chinese University of Hong Kong",2,{"id":258,"slug":259,"hasResults":11,"nctId":260,"briefTitle":261,"officialTitle":261,"acronym":4,"eligibilityCriteria":262,"healthyVolunteers":16,"sex":17,"minAge":263,"maxAge":264,"enrollmentInfo":265,"targetDuration":4,"studyType":132,"phases":4,"briefSummary":267,"conditions":268,"keywords":4,"overallStatus":46,"whyStopped":4,"lastUpdateSubmitDate":270,"lastUpdatePostDateStruct":271,"startDateStruct":273,"completionDateStruct":275,"leadSponsor":277,"locationsCount":58},"100575815","evaluation-of-motor-skills-balance-dual-task-and-social-adaptation-in-individuals-with-autism-100575815","NCT06777186","Evaluation of Motor Skills, Balance, Dual Task, and Social Adaptation in Individuals with Autism","Inclusion Criteria:\n\n* Being diagnosed with ASD by a physician\n* Children are receiving education in a special education and rehabilitation center\n* No vision problems\n* Ability to receive and execute commands\n* No cognitive problems\n* No walking problems\n\nExclusion Criteria:\n\n* Individuals with concomitant secondary diseases\n* Individuals who have undergone surgery in the last six months","4 Years","21 Years",{"count":266,"type":22},55,"The aim of our study is to evaluate motor skills balance, dual task and social adaptation skills in individuals with autism. Our study will be conducted in Bartın Lider Special Education and Rehabilitation Center after ethics committee approval. The sample number determined by power analysis will be included in the study. Socio-demographic characteristics (age, height, body weight, body mass index, education level, exercise and smoking habits, etc.) of the individuals who voluntarily participated in the study will be obtained. The individuals participating in the study will be divided into two groups as individuals with normal motor development and individuals with autism spectrum disorder and the same assessment scales will be used. These assessment scales are TUG, 10 meter walking test, Vineland Adaptive Adaptation Scale, Bruininks-Oseretsky Motor Competence Test. According to the evaluation results, motor skills, functional balance, dual task and social adaptation skills of individuals with autism will be compared with individuals with normal motor development.",[231,28,269],"Social Skills","2025-01-10",{"date":272,"type":50},"2025-01-15",{"date":274,"type":50},"2024-12-15",{"date":276,"type":22},"2025-11-25",{"name":278,"class":57},"Kırıkkale University",{"id":280,"slug":281,"hasResults":11,"nctId":282,"briefTitle":283,"officialTitle":283,"acronym":4,"eligibilityCriteria":284,"healthyVolunteers":16,"sex":17,"minAge":285,"maxAge":286,"enrollmentInfo":287,"targetDuration":4,"studyType":132,"phases":4,"briefSummary":289,"conditions":290,"keywords":291,"overallStatus":46,"whyStopped":4,"lastUpdateSubmitDate":293,"lastUpdatePostDateStruct":294,"startDateStruct":296,"completionDateStruct":298,"leadSponsor":300,"locationsCount":58},"100556194","combined-artificial-intelligence-and-mobile-application-for-remote-infant-motor-screening-development-and-validation-100556194","NCT06521918","Combined Artificial Intelligence and Mobile Application for Remote Infant Motor Screening: Development and Validation","The inclusion criterion is:\n\nPreterm infants: gestational age \\\u003C 37 weeks, birth body weight \\\u003C 2,500 grams, and corrected age of 2-18 months.\n\nTerm infants: gestational age 37-42 weeks, birth body weight \\>2,500 grams, and age of 2-18 months.\n\nClinicians: who provide early intervention to the participating infants in this study.\n\nThe exclusion criterion is:\n\nInfants: parents can not read Chinese. Clinicians: can not read Chinese","2 Months","18 Months",{"count":288,"type":22},242,"The purpose of this study is therefore five-fold: (1) designation of an APP \"Baby Go\" version 3.0 to include the assessment, follow-up, and education functions for parental use at home, (2) development and validation of the AI algorithm for infant motor assessment based on home videos obtained from term and preterm infants, (3) comparison of parental perception and report with AI-driven assessment results, (4) examination of the predictive validity of the AI algorithm for infant motor assessment on subsequent outcome, and (5) investigation of the usability of the APP \"Baby Go\" version 3.0 in parents and clinicians.",[28],[292],"AI, infant motor assessment, APP, validation","2025-01-09",{"date":295,"type":50},"2025-01-13",{"date":297,"type":50},"2024-10-17",{"date":299,"type":22},"2027-07-31",{"name":301,"class":57},"National Taiwan University Hospital",{"id":303,"slug":304,"hasResults":11,"nctId":305,"briefTitle":306,"officialTitle":307,"acronym":4,"eligibilityCriteria":308,"healthyVolunteers":16,"sex":17,"minAge":67,"maxAge":18,"enrollmentInfo":309,"targetDuration":4,"studyType":23,"phases":310,"briefSummary":311,"conditions":312,"keywords":4,"overallStatus":112,"whyStopped":4,"lastUpdateSubmitDate":314,"lastUpdatePostDateStruct":315,"startDateStruct":317,"completionDateStruct":318,"leadSponsor":319,"locationsCount":4},"100556050","motor-control-prevention-strategies-in-basketball-players-100556050","NCT06520046","Motor Control Prevention Strategies in Basketball Players","Motor Control Prevention Strategies for Ankle Sprains in Basketball Players","Inclusion Criteria:\n\n* Basketball players aged between 10-18 years old who play regularly in one of the basketball clubs in the city of Salamanca.\n\nExclusion Criteria:\n\n* previous injuries\n* fractures\n* use of orthoses and technical aids",{"count":164,"type":22},[25],"Ankle sprains have always been considered as isolated injury entities, in which the passive ankle stabilisation system suffered an elongation due to trauma. Today, this concept of an isolated injury has evolved into a more holistic concept, interrelated with various components from different sources.",[313,28],"Ankle Sprains","2024-12-04",{"date":316,"type":50},"2024-12-09",{"date":274,"type":22},{"date":253,"type":22},{"name":320,"class":57},"University of Salamanca",{"id":322,"slug":323,"hasResults":11,"nctId":324,"briefTitle":325,"officialTitle":326,"acronym":4,"eligibilityCriteria":327,"healthyVolunteers":11,"sex":17,"minAge":328,"maxAge":329,"enrollmentInfo":330,"targetDuration":4,"studyType":132,"phases":4,"briefSummary":332,"conditions":333,"keywords":337,"overallStatus":112,"whyStopped":4,"lastUpdateSubmitDate":346,"lastUpdatePostDateStruct":347,"startDateStruct":348,"completionDateStruct":350,"leadSponsor":352,"locationsCount":4},"100565710","neuromotor-development-and-motor-related-health-care-in-children-with-a-high-risk-neonatal-period-100565710","NCT06645717","Neuromotor Development and Motor Related Health Care in Children with a High Risk Neonatal Period","Neuromotor Development in Children Enrolled in the Swedish Neonatal Follow-up Program and Access to Motor Related Healthcare","Inclusion Criteria:\n\n* Included in the SNQ registry and having a follow-up protocol for 2 and\u002For 5 years of age.\n\nExclusion Criteria:\n\n* None if the above inclusion criteria ar true.","2 Years","14 Years",{"count":331,"type":22},2900,"The overall aim of the study is to evaluate the prevalence of motor- and neurological disorders (cerebral pares and other less severe motor disorders) in Swedish infants with a high-risk neonatal period and to elucidate whether these children receive motor related health care (MRHC) at 2 and or 5,5 years of age.",[28,233,334,335,336],"Premature Birth","Hypoxic-Ischemic Encephalopathy","Small for Gestational Age At Delivery",[338,339,340,341,342,343,344,345],"brain","HIE","SGA","preterm","neurodevelopment","motor related healthcare","children","motor function","2024-10-14",{"date":297,"type":50},{"date":349,"type":22},"2025-01-01",{"date":351,"type":22},"2034-10-01",{"name":353,"class":57},"Karolinska Institutet",{"id":355,"slug":356,"hasResults":11,"nctId":357,"briefTitle":358,"officialTitle":359,"acronym":4,"eligibilityCriteria":360,"healthyVolunteers":11,"sex":17,"minAge":264,"maxAge":4,"enrollmentInfo":361,"targetDuration":4,"studyType":23,"phases":363,"briefSummary":364,"conditions":365,"keywords":366,"overallStatus":46,"whyStopped":4,"lastUpdateSubmitDate":375,"lastUpdatePostDateStruct":376,"startDateStruct":378,"completionDateStruct":380,"leadSponsor":382,"locationsCount":256},"100506311","fab-programme-for-parents-of-children-with-ndd-100506311","NCT05872737","FAB Programme for Parents of Children With NDD","Facilitator-guided Acceptance and Commitment Bibliotherapy for Parents of Young Children With Neurodevelopmental Disorders: A Randomised Controlled Trial","Parents of young children with NDD who fulfil the following criteria will be recruited:\n\n* Cantonese-speaking Hong Kong residents,\n* aged ≥ 21 years,\n* have a child aged between two and six years old (preschool age) with a clinically documented diagnosis\u002Fsuspected NDD diagnosis according to DSM-5 criteria (e.g., ASD, ADHD, developmental delay) and enrolled in the SWD subvented pre-school rehabilitation services offered by NGOs,\n* caregivers who adopted the responsibility of taking care of the child, living together with the child, and\n* have device(s) with internet access.\n\nParents of young children with NDD will be excluded if:\n\n* has been diagnosed with severe mental illness(es),\n* cognitive\u002Flanguage\u002Fcommunication\u002Fvisual\u002Fhearing impairment(s) or disorders that may present difficulties in comprehending the content of the intervention; and\u002For\n* are currently receiving another psychosocial, psychoeducational, or parenting intervention(s).",{"count":362,"type":22},154,[25],"The study aims to examine the effectiveness of a psychotherapy approach called Facilitator-guided Acceptance and Commitment Bibliotherapy (FAB) in improving the psychological health of parents of young children with neurodevelopmental disorders (NDD) and reducing the emotional and behavioral symptoms of NDD children. The study will involve 154 Cantonese-speaking parents of children aged 2-6 years diagnosed with NDD in Hong Kong. The study hopes to find that FAB can improve parent-child dyads' health outcomes by enhancing psychological flexibility, parental psychological health, and mindful parenting skills.",[231,232,233,234,235,136,28],[367,368,369,370,371,372,373,374,239],"Neurodevelopmental disorders","Facilitator-guided Acceptance and Commitment Bibliotherapy","Parental psychological health","Parenting stress","Repeated-measures parallel-group design","Randomized controlled trial","Psychological flexibility","Hong Kong","2024-09-13",{"date":377,"type":50},"2024-09-19",{"date":379,"type":50},"2023-06-05",{"date":381,"type":22},"2026-09-08",{"name":255,"class":57},{"id":384,"slug":385,"hasResults":11,"nctId":386,"briefTitle":387,"officialTitle":387,"acronym":388,"eligibilityCriteria":389,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":390,"targetDuration":4,"studyType":23,"phases":391,"briefSummary":392,"conditions":393,"keywords":398,"overallStatus":46,"whyStopped":4,"lastUpdateSubmitDate":404,"lastUpdatePostDateStruct":405,"startDateStruct":407,"completionDateStruct":409,"leadSponsor":411,"locationsCount":58},"100557504","adherence-to-long-term-exoskeleton-rehabilitation-to-treat-lower-limb-weakness-and--or-deficiencies-in-adult-population-100557504","NCT06538974","Adherence to Long-term Exoskeleton Rehabilitation to Treat Lower Limb Weakness and \u002F or Deficiencies in Adult Population","ALERT","Inclusion Criteria:\n\n* Patient suffering from lower limb weaknesses and \u002F or deficiencies regardless of the cause\n* Adult patient ≥18 years old\n* Patient able to read and write in French and who have signed an informed consent form\n* Patient affiliated to a social security system.\n\nExclusion Criteria:\n\n* Individual with severe spasticity of adductor muscles, hamstring, quadriceps and triceps surae. Severe spasticity is defined by a score of 4 on the modified Ashworth scale\n* Pregnant woman\n* Individual with history of osteoporotic fracture and \u002F or pathology or treatment causing secondary osteoporosis\n* Pressure Ulcer of Grade I or higher according to the NPUAP International Pressure Ulcer Classification System- EPUAP, in areas of contact with the Atalante X system\n* Severe aphasia limiting ability to express needs or to fulfil questionnaires, at the discretion of the physician.\n* Patient with a cardiac or respiratory contraindication to physical exertion, at discretion of the physician\n* Patient unable to deliver his\u002Fher consent\n* Patient under legal protection\n* Patient participating at the same time in another study\n* Patients with morphological contraindications to the use of the Atalante X exoskeleton (as per user's manual) with exceptions as follows: knee flessum of 20° authorized if sensibility is present; equinus of the ankle of 20° allowed regardless of presence or absence of sensibility, hip flessum of 20° allowed regardless of presence or absence of sensibility.",{"count":21,"type":22},[25],"In 2019, approximately 2.4 billion people worldwide required rehabilitation for various health pathologies, a 63% increase since 1990. It has been suggested that current rehabilitation frameworks (inpatient, outpatient, and community-based) are insufficient to meet local population needs due to issues like long waiting times, lack of facilities, prioritization, funding, and accessibility.Patients with lower limb weaknesses, resulting from various conditions (for example stroke, traumatic brain injury, spinal cord injury and others) require long-term management and motivation for engagement, which are crucial for functional outcomes. This highlights the need for sustainable gait and balance rehabilitation.\n\nNew technologies like exoskeletons have shown promising results in short-term inpatient programs, improving gait, balance, and quality of life, however, long-term follow-up data are still needed.\n\nThe present clinical investigation is a national, prospective, open-label interventional trial, proposing a 12-month outpatient rehabilitation program with the Atalante X exoskeleton to treat lower limb weakness and\u002For impairments in 100 participants. The rehabilitation program consists of at least one exoskeleton rehabilitation session per week. At the end of the first-year experimental phase, participants can continue for an additional year in the voluntary phase. The program aims to explore the potential long-term effects of supervised robotic rehabilitation on motor, cognitive, bowel, bladder functions, quality of life, and well-being. Assessments are conducted at baseline, after 4 and 12 months of exoskeleton rehabilitation, and at 16 and 24 months for participants in the voluntary phase.",[28,394,395,30,396,397],"Gait Disorders, Neurologic","Neurodegenerative Diseases","Weakness, Muscle","Cerebrovascular Accident",[399,400,401,402,403],"Hands-free Exoskeleton","Atalante X","Gait","Balance","Rehabilitation","2024-07-31",{"date":406,"type":50},"2024-08-06",{"date":408,"type":50},"2023-02-16",{"date":410,"type":22},"2027-07-02",{"name":412,"class":413},"Wandercraft","INDUSTRY",{"id":415,"slug":416,"hasResults":11,"nctId":417,"briefTitle":418,"officialTitle":419,"acronym":420,"eligibilityCriteria":421,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":422,"enrollmentInfo":423,"targetDuration":4,"studyType":132,"phases":4,"briefSummary":424,"conditions":425,"keywords":426,"overallStatus":46,"whyStopped":4,"lastUpdateSubmitDate":430,"lastUpdatePostDateStruct":431,"startDateStruct":433,"completionDateStruct":435,"leadSponsor":437,"locationsCount":256},"100552188","french-translationadaptation-of-ahemd-sr-fr-ahemd-100552188","NCT06469840","French Translation\u002FAdaptation of AHEMD-SR (FR-AHEMD)","French Translation\u002FAdaptation of Affordances in the Home Environnent for Motor Development Self-Report (AHEMD-SR)","FR-AHEMD","Parents Group :\n\nInclusion Criteria:\n\n* Parents of a child aged 18 to 42 months with a diagnosis of delayed motor development\n* Taken in charge in one of the participating centers for an intensive motor rehabilitation training\n* Francophone by birth\n\nExclusion Criteria:\n\n* Parent opposing participation in the study\n\nExperts Group :\n\nInclusion Criteria:\n\n* Professional\n* Holding a French state diploma in the field of rehabilitation\n* Participating in an intensive motor rehabilitation training in one of the participating centres.\n* Proof of experience in paediatric rehabilitation (lasting 5 years).\n* Francophone by birth\n\nNon-inclusion criteria :\n\n\\- Expert opposing participation in the study","99 Years",{"count":227,"type":22},"The aim of this study is to develop a French translation and adaptation of the original English version of the AHEMD-SR.",[28],[427,428,429],"AHEMD-SR","Motor Development","Pediatric rehabilitation","2024-07-08",{"date":432,"type":50},"2024-07-09",{"date":434,"type":50},"2024-06-21",{"date":436,"type":22},"2025-01",{"name":438,"class":57},"Fondation Ildys"]