[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"motor-neuron-disease--amyotrophic-lateral-sclerosis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:motor-neuron-disease--amyotrophic-lateral-sclerosis":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100449725","polysomnographic-titration-of-non-invasive-ventilation-in-motor-neurone-disease-100449725",false,"NCT05136222","Polysomnographic Titration of Non-invasive Ventilation in Motor Neurone Disease","A Multi-centre Randomised Controlled Trial of Polysomnographic Titration of Non-invasive Ventilation in Motor Neurone Disease (PSG4NIVinMND; 3, Three Letter Acronyms [3TLA])","3TLA","Inclusion Criteria:\n\n* Age \\>18 years\n* Clinical indication to commence long term NIV\n* Confirmed clinical diagnosis of underlying condition\n\nExclusion Criteria:\n\n* Medically unstable\n* Hypoventilation attributable to medications with sedative\u002Frespiratory depressant side- effects\n* Use of NIV for more than 1 month in the previous 3 months\n* Inability to provide informed consent\n* Previous intolerance of NIV","ALL","18 Years",{"count":20,"type":21},244,"ESTIMATED","INTERVENTIONAL",[24],"NA","A two-arm, individual participant randomised controlled, assessor-blinded trial in 7 MND care centres across Australia will be undertaken.",[27],"Motor Neuron Disease \u002F Amyotrophic Lateral Sclerosis",[29,30,31,32,33],"Non-invasive ventilation","Polysomnography","Sleep study","Amyotrophic lateral sclerosis","Chronic respiratory failure","RECRUITING","2022-06-19",{"date":37,"type":38},"2022-06-23","ACTUAL",{"date":40,"type":38},"2021-12-15",{"date":42,"type":21},"2028-02-28",{"name":44,"class":45},"University of Melbourne","OTHER",13]