[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"motor-rehabilitation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:motor-rehabilitation":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,46],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100588195","phase-1-wether-vns-in-early-stage-3-months-is-safe-and-more-beneficial-for-post-stroke-motor-rehabilitation-100588195",false,"NCT06938243","Wether VNS in Early Stage (3 Months) is Safe and More Beneficial for Post-stroke Motor Rehabilitation","The Comparison of Safety and Treatment Results Between Early (\u003C6 Months) and Late (> 6 Months) Vagus Stimulation for Post-stroke Motor Rehabilitation: a Randomized Clinical Trial","Inclusion Criteria:\n\n* Eligible individuals suffered a first-time, unilateral, ischemic stroke in the middle cerebral artery territory that spared the diencephalon and basal ganglia 3-36 months before surgery.\n\n  * Individuals with persistent moderate-to-severe upper-extremity hemiparesis as defined by an FM-UE score of ≤42\n  * Sufficient upper-extremity motor ability to engage in rehabilitation (that is, a score of ≥1 on the FM-UE elbow flexion, elbow extension or finger mass flexion or extension).\n\nExclusion Criteria:\n\n* Excessive spasticity or contracture of the upper-extremity muscles (that is, Modified Ashworth Scale = 4) . Severe cognitive impairment (Mini Mental State Examination \\\u003C 24)","ALL","30 Years","75 Years",{"count":20,"type":21},100,"ESTIMATED","INTERVENTIONAL",[24],"PHASE1","Upper-extremity impairment after stroke remains a major therapeutic challenge and a target of neuromodulation treatment efforts. In previous study, Vagus nerve stimulation was constricted to patients 9 months after stroke. In this randomized phase I trial, we would apply vagus nerve stimulation in an early stage (\\\u003C6 month) and observe its theraputic effect on motor function after ischaemic Stroke.We hypothesized that the early stimulation could be safe and more beneficial compared to stimulation in late stage.",[27,28],"Stroke","Motor Rehabilitation",[30,31,32],"Hemiparesis","VNS","Limb Motor Function Rehabilitation","RECRUITING","2025-04-14",{"date":36,"type":37},"2025-04-22","ACTUAL",{"date":39,"type":21},"2025-05-01",{"date":41,"type":21},"2026-12-30",{"name":43,"class":44},"Qilu Hospital of Shandong University","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":54,"sex":16,"minAge":55,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":58,"briefSummary":60,"conditions":61,"keywords":4,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":45},"100579590","cervical-tsdcs-on-stroke-patients-100579590","NCT06826274","Cervical TsDCS on Stroke Patients","Clinical and Neurophysiological Evaluation of the Effects of Cervical TsDCS on Stroke Patients with Distal Upper Limb Strength Deficit","AMPLI-MOV","Group Stroke:\n\nInclusion criteria:\n\n1. age over 18 years;\n2. first ischemic\u002Fhemorrhagic stroke (within 30 days of onset);\n3. mild-to-moderate stroke (NIHSS scale score\\\u003C16).\n4. residual function of the upper limb, assessed by the following scales: - MRC of the distal muscles of the upper limb: score between 2 and 4; - NHISS (items 5A and 5B): score between 1 and 3;\n5. ability to give informed consent and understand instructions.\n\nExclusion criteria:\n\n1. severe spasticity (Ashworth Scale score \\> 2);\n2. severe aphasia;\n3. severe neglect;\n4. history of disabling neurological disease;\n5. history of epilepsy;\n6. significant comorbidities;\n7. contraindications to tsDCS.\n\nHealthy Group:\n\nInclusion criteria:\n\n1. age over 18 years;\n2. equalized in age with the patient group.\n\nExclusion criteria:\n\n1. history of stroke progress;\n2. history of severe neurological disease.",true,"18 Years",{"count":57,"type":21},40,[59],"NA","The present project aims to evaluate the facilitatory modulation of motor responses of the limb upper limb by tsDCS in patients with arm\u002Fhand hyposthenia after cerebral ischemia to verify the possible therapeutic benefits that this type of stimulation can induce in terms of of strength, dexterity and effectiveness in acts of daily living.",[62,28],"Functional Recovery","NOT_YET_RECRUITING","2025-02-12",{"date":66,"type":37},"2025-02-13",{"date":68,"type":21},"2025-03",{"date":70,"type":21},"2026-03",{"name":72,"class":44},"IRCCS San Raffaele Roma"]