[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"motor-symptoms\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:motor-symptoms":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,44],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":4},"100641633","hf-rtms-primed-balance-training-on-corticomotor-excitability-balance-and-gait-in-parkinsons-100641633",false,"NCT07653256","HF-rTMS Primed Balance Training on Corticomotor Excitability, Balance, and Gait in Parkinson's","Effects of High-frequency Repetitive Transcranial Magnetic Stimulation-primed Balance Training on Corticomotor Excitability, Balance, and Gait Performance in Parkinson's Disease","Inclusion Criteria:\n\n* Diagnosed with idiopathic PD\n* Aged between 40-80 years\n* Stable on antiparkinsonian medication ( \\> 3 months)\n* H\\&Y I-III\n* Able to walk continuously for at least 10 minutes\n* The ability to follow commands and instructions\n\nExclusion Criteria:\n\n* Neurological diseases other than PD\n* Severe musculoskeletal, cardiopulmonary disorders\n* MMSE \\\u003C 24\n* Contraindications for TMS\n* Have undergone or are scheduled to undergo neurological surgery during the study participation period","ALL","40 Years","80 Years",{"count":20,"type":21},20,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study aims to investigate the effects of repeated transcranial magnetic stimulation combined with modified otago exercise program balance training intervention on motor cortex excitability, balance, and gait performance in patients with Parkinson's disease.",[27,28,29,30,31],"Parkinson's Disease","Corticomotor Excitability","Balance Control","Gait Performance","Motor Symptoms","NOT_YET_RECRUITING","2026-06-11",{"date":35,"type":36},"2026-06-17","ACTUAL",{"date":38,"type":21},"2026-07-01",{"date":40,"type":21},"2028-04-01",{"name":42,"class":43},"Chung Shan Medical University","OTHER",{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":51,"targetDuration":4,"studyType":22,"phases":53,"briefSummary":54,"conditions":55,"keywords":57,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":5},"100632792","remotely-supervised-home-based-transcranial-temporal-interference-stimulation-on-motor-symptoms-in-parkinsons-disease-100632792","NCT07518290","Remotely Supervised Home-based Transcranial Temporal Interference Stimulation on Motor Symptoms in Parkinson's Disease","Remotely Supervised Home-based Transcranial Temporal Interference Stimulation on Motor Symptoms in Parkinson's Disease: Protocol For a Double Blind Randomized Controlled Trial","Inclusion Criteria:\n\n* Diagnosis of Parkinson's disease according to established clinical criteria\n* Mild-to-moderate disease severity, defined as Hoehn and Yahr stage 1.5-3;\n* Age between 40 and 80 years;\n* Stable anti-parkinsonian medication regimen;\n* Ability to walk unaided for at least 2 minutes.\n\nExclusion Criteria:\n\n* contraindications to TIs (e.g., metal implantation, pacemakers, etc.);\n* the use of DBS;\n* significant cognitive impairment as defined by the diagnosis of Alzheimer's disease or dementia, or Montreal Cognitive Assessment (MoCA) total score\\\u003C21, a recommended threshold for dementia in PD;\n* diagnosis of other neurological conditions such as multiple sclerosis, previous stroke;\n* report of severe lower-extremity arthritis, pain, or orthopedic problems significantly affecting gait;\n* physician-diagnosis of schizophrenia or other psychiatric illness;\n* an unwillingness to cooperate or participate in the study protocol. Eligible and interested participants will then be enrolled and complete baseline assessments before the randomization.",{"count":52,"type":21},68,[24],"The goal of this clinical trial is to learn if home-based temporal interference stimulation (TIS) works to improve motor symptoms in people with Parkinson's disease (PD). It will also learn about the safety of this treatment. The main questions it aims to answer are:\n\n1. Does home-based TIS improve movement problems such as slow movement, stiffness, and walking difficulty?\n2. Are the effects maintained after the treatment ends?\n3. What medical problems (adverse events) occur during treatment? Researchers will compare active TIS to a sham treatment (a look-alike procedure that does not deliver active stimulation) to see if TIS works.\n\nParticipants will:\n\n1. Receive active TIS or sham stimulation once a day for 4 weeks at home under remote supervision\n2. Visit the clinic at specific time points for movement assessments\n3. Complete online questionnaires about symptoms and quality of life",[56,31],"PARKINSON DISEASE (Disorder)",[58,59,60,61,62],"Parkinson disease","Transcranial temporal interference stimulation","Home-based intervention","Motor symptom","Randomized controlled trial","RECRUITING","2026-04-09",{"date":66,"type":36},"2026-04-14",{"date":68,"type":21},"2026-04-04",{"date":70,"type":21},"2028-03-30",{"name":72,"class":43},"Shanghai University of Sport"]