[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"mta-vital-tooth-pulpotomy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:mta-vital-tooth-pulpotomy":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,49],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100639316","r-officinalis-as-pulpotomy-agent-in-permanent-teeth-with-irreversible-pulpitis-100639316",false,"NCT07610057","R. Officinalis as Pulpotomy Agent in Permanent Teeth With Irreversible Pulpitis","Comparative Clinical and Radiographic Evaluation of Rosmarinus Officinalis Versus Mineral Trioxide Aggregate as Pulpotomy Medicament in Vital Mature Permanent Teeth With Irreversible Pulpitis","Inclusion Criteria\n\n* Healthy patients (ASA classification 1 and 2) of age range of 18-40 of both sexes would be included.\n* Vital mature permanent posterior teeth with deep caries approaching the pulp as seen on periapical x-ray.\n* Pain indicative of irreversible pulpitis (spontaneous pain or pain exacerbated by a cold stimulus which could last from a few seconds to hours), which a cold test could reproduce.\n* Tooth will be selected on the basis of working diagnosis i.e. successful hemostasis within 5 minutes after removal of coronal pulp.\n* Absence of clinical signs or symptoms suggesting a non-vital tooth such as tenderness to percussion or palpation, mobility, presence of abscess, soft tissue swelling or suppurating sinus.\n* Absence of radiographic changes as; furcation or periapical pathology, internal or external root resorption or calcification in the canals.\n* The tooth structure of selected teeth should be restorable after completion of the treatment\n\nExclusion Criteria:\n\n* Patients with ASA classification 3, 4 ,5 and 6 would be\n* Patients taking antibiotics within last 2 weeks.\n* Teeth with pulp necrosis, cracked tooth, internal or external resorption, calcified canals, acute or chronic apical periodontitis with an associated sinus tract or periapical radiolucency.\n* Periodontally compromised tooth.\n* Uncooperative patients or failure to obtain authorization from patients.","ALL","18 Years","40 Years",{"count":20,"type":21},100,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study evaluates and compares the clinical and radiographic outcomes of Rosmarinus officinalis and Mineral Trioxide Aggregate (MTA) when used as pulpotomy medicaments in vital mature permanent teeth with irreversible pulpitis. The aim is to determine the effectiveness of both materials in terms of pain reduction and periapical healing. While MTA is considered a gold standard, it has limitations such as high cost, long setting time, and potential discoloration. Therefore, this study investigates Rosmarinus officinalis as a natural, cost-effective alternative with comparable therapeutic potential. This study also provide an alternative to RCT in teeth with irreversible pulpitis",[27,28,29],"Irreversible Pulpitis","Pulpotomy","MTA Vital Tooth Pulpotomy",[31,32,33,34,35],"pulpotomy","rosemarinus officinalis","MTA","permanent teeth with irreversible pulpitis","Vital pulp theray","NOT_YET_RECRUITING","2026-05-21",{"date":39,"type":40},"2026-05-27","ACTUAL",{"date":42,"type":21},"2026-06-01",{"date":44,"type":21},"2026-12-31",{"name":46,"class":47},"University of Health Sciences Lahore","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":56,"sex":16,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":4,"studyType":22,"phases":61,"briefSummary":62,"conditions":63,"keywords":64,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":48},"100570733","clinical--radiographic-efficacy-using-lllt--cryo-on-mpm-pulpotomy-100570733","NCT06711081","Clinical & Radiographic Efficacy Using LLLT & CRYO on M.P.M Pulpotomy","Clinical and Radiographic Evaluation Following Complete Pulpotomy Using Low Level LASER Therapy and Cryotherapy","Inclusion Criteria:\n\n* • Restorable vital and mature mandibular molar teeth with irreversible pulpitis.\n\n  * Teeth with deep caries or large restoration.\n  * Pre-operative radiograph showing normal periapical structure.\n  * Teeth with normal periodontal status .\n\nExclusion Criteria:\n\n* • Medically compromised patients with active systemic disease as uncontrolled diabetes mellitus, hypertension or cardiac diseases.\n\n  * Teeth with periapical lesion.\n  * Sinus tract or swelling.\n  * Moderate or severe marginal periodontitis.\n  * Patient allergic to any material or medication used in this study.\n  * Teeth with moderate to severe mobility.\n  * Teeth with periodontal diseases.\n  * Teeth with anatomical variations.",true,"15 Years","60 Years",{"count":60,"type":21},30,[24],"This in-vivo study aims to evaluate the efficacy of the low level laser therapy and cryotherapy in treatment of vital pulpotomy in mature permanent molar evaluating the post operative pain and the radiographic changes in pulpal and periodontal regions.",[29],[65],"vital pulp therapy permanent teeth pulpotomy LLLT","RECRUITING","2024-11-28",{"date":69,"type":40},"2024-12-02",{"date":71,"type":21},"2024-11",{"date":73,"type":21},"2025-11",{"name":75,"class":47},"Tanta University"]