[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"mtbi---mild-traumatic-brain-injury\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:mtbi---mild-traumatic-brain-injury":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,48,77,101],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":32,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":4},"100644586","phase-2-bcaas-in-concussion-30-100644586",false,"NCT07670195","BCAAs in Concussion 3.0","HIT HEADS 3.0: Head Injury Treatment: A Randomized, Placebo-controlled, Double-blinded, Therapeutic Clinical Trial of Branched Chain Amino Acids (BCAAs) in the Treatment of Concussion","Inclusion Criteria:\n\n1. Males and females,11 - 23 years of age.\n2. Weigh at least 40kg.\n3. Meeting concussion criteria for the American Congress of Rehabilitative Medicine.\n\n   a. One or more clinical signs or two or more acute symptoms with at least one VVE abnormality.\n4. Present within 4 days of injury.\n5. Post-menarchal females must have a negative urine pregnancy test.\n6. Informed consent by the participant, or for participants \\\u003C18 years old both informed consent by a parent\u002Fguardian and child assent.\n\nExclusion Criteria:\n\n1. Evidence of moderate or severe TBI, including GCS \\\u003C13, TBI requiring hospital admission, or TBI requiring neurosurgical intervention.\n2. Prior concussion or TBI within 90 days.\n3. Known history of maple syrup urine disease or known family history of maple syrup urine disease.\n4. Any investigational drug use within 30 days prior to enrollment.\n5. Participants who are pregnant, planning on becoming pregnant during the study duration, or breastfeeding.\n6. Non-English speaking participants or parent\u002Fguardian.",true,"ALL","11 Years","23 Years",{"count":21,"type":22},150,"ESTIMATED","INTERVENTIONAL",[25],"PHASE2","This study is a randomized, placebo-controlled, double-blinded, therapeutic exploratory clinical trial of branched chain amino acids (BCAAs) in the treatment of concussion. The aim of the study is to determine whether administration of high-dose BCAAs compared to placebo promotes concussion recovery.",[28,29,30,31],"Concussion (Diagnosis)","MTBI - Mild Traumatic Brain Injury","Concussion, Brain","Concussion",[31,33,34,35],"mTBI","BCAAs","Branched Chain Amino Acids","NOT_YET_RECRUITING","2026-06-19",{"date":39,"type":40},"2026-06-26","ACTUAL",{"date":42,"type":22},"2026-07",{"date":44,"type":22},"2027-12",{"name":46,"class":47},"Akiva Cohen","OTHER",{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":16,"sex":17,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":57,"phases":4,"briefSummary":58,"conditions":59,"keywords":60,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":76},"100614676","validation-of-clinical-outcome-measures-specific-to-mtbi-related-oculomotor-disorders-100614676","NCT07282691","Validation of Clinical Outcome Measures Specific to mTBI-Related Oculomotor Disorders","Inclusion Criteria:\n\n* Diagnosis of mTBI within previous 1 to 6 months\n* Distance visual acuity better than or equal to 20\u002F25 in each eye\n* Score \\>21 on Convergence Insufficiency Symptom Survey\n\nExclusion Criteria:\n\n* Diagnosis of moderate or severe TBI; \\> 30-min loss of consciousness\n* Not wearing required refractive error)\n* Disease(s) known to affect oculomotor system (multiple sclerosis, Graves orbitopathy, myasthenia gravis, diabetes mellitus, or Parkinson disease)-Manifest strabismus or intraocular injury (evaluated at vision examination)\n* Cognitive delays that may impact testing","18 Years","35 Years",{"count":21,"type":22},"OBSERVATIONAL","The specific aim of this project is to validate clinical tests to be used as outcome measures in studies of mTBI-related vision problems.",[29],[33,61,62,63,64,65],"convergence insufficiency","concussion","concussion-related vision disorders","vision rehabilitation","vision therapy","RECRUITING","2025-12-01",{"date":69,"type":40},"2025-12-15",{"date":71,"type":40},"2025-04-01",{"date":73,"type":22},"2028-09-29",{"name":75,"class":47},"Salus University",1,{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":83,"eligibilityCriteria":84,"healthyVolunteers":16,"sex":17,"minAge":85,"maxAge":4,"enrollmentInfo":86,"targetDuration":4,"studyType":57,"phases":4,"briefSummary":87,"conditions":88,"keywords":4,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":100},"100607623","mindrhythm-detection-of-concussion-and-recovery-study-100607623","NCT07190963","MindRhythm Detection of Concussion and Recovery Study","Detection of Concussion and Recovery Study","DISCOVERY","Inclusion Criteria: An individual who has been diagnosed with or suspected to have a concussion or mTBI.\n\n\\-\n\nExclusion Criteria: open wounds on the head. Pregnant women due to unexpected risks. Subjects under the age of 4.\n\n\\-","4 Years",{"count":21,"type":22},"This study is designed to observe HeadPulse data in concussed subjects that may have experienced a concussion via an injury down to the age of 4. Sports teams are the focus of this study because therein lies inherent potential risk for concussion. This observational study will further confirm the data previously collected in professional athletes to further validate that the HeadPulse can be used as a digital biometric to objectively indicate when a concussed brain remains concussed despite a subject feeling no symptoms has extreme value. This study is intended to support the development of a device to objectively determine when it is safe to return to play or normal activity based on the output of the digital biometric.",[89],"mTBI - Mild Traumatic Brain Injury","2025-09-22",{"date":92,"type":40},"2025-09-24",{"date":94,"type":40},"2025-01-28",{"date":96,"type":22},"2027-03-30",{"name":98,"class":99},"MindRhythm, Inc.","INDUSTRY",2,{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":106,"acronym":4,"eligibilityCriteria":107,"healthyVolunteers":11,"sex":17,"minAge":54,"maxAge":108,"enrollmentInfo":109,"targetDuration":4,"studyType":23,"phases":111,"briefSummary":113,"conditions":114,"keywords":119,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":129,"lastUpdatePostDateStruct":130,"startDateStruct":132,"completionDateStruct":134,"leadSponsor":136,"locationsCount":76},"100568606","effectiveness-of-vestaid-app-100568606","NCT06683417","Effectiveness of VestAid App","Vestibular Rehabilitation Aid (VestAid)","Inclusion:\n\n* Snellen visual acuity (corrected) greater than 20\u002F40\n* No more than 25dB hearing loss at 500,1000, 2000, and 4000 Hz\n* Ability to detect 4.31 using Semmes-Weinstein monofilament at the lower extremity\n* At least 40 degrees of neck yaw motion with only mild to moderate pain (6 or under on 0-10 numeric pain scale)\n* Internet access at home\n* No significant residual from past musculoskeletal or neuromuscular conditions\n* Ability ambulates unassisted\n* Diagnosed with a concussion or inner ear problem the last 30 days\n* Between 18-60 years of age\n* Can read and understand English\n* Has complaints of dizziness\n\nExclusion criteria:\n\n* Greater then 30 days since diagnosis of concussion\u002FmTBI or inner ear problem\n* No access to internet at home\n* Younger than 18 years of age or older than 60 years of age\n* Cannot read or understand English\n* No complaints of dizziness and\u002For balance deficits\n* Have significant neuropathy\n* Cannot see tablet clearly at 1 meter\n* Neck pain \\>5 on a 10-point pain scale.","60 Years",{"count":110,"type":22},80,[112],"NA","This multi-center randomized trial (MCRT) will investigate the effectiveness of the VestAid application to provide equivalent or faster recovery from dizziness compared to standard-of-care delivery of vestibular rehabilitation exercises.",[29,115,116,117,118],"Vestibular Disease","Balance Deficits","Vestibular Disorders","Dizziness",[33,120,121,122,123,124,125,126,127,128],"vestibular rehabilitation","vestibular disorder","technology","application","dizziness","balance disorder","image processing","eye gaze compliance","VOR","2024-11-08",{"date":131,"type":40},"2024-11-12",{"date":133,"type":22},"2025-01-15",{"date":135,"type":22},"2025-12-30",{"name":137,"class":99},"BlueHalo"]