[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"muscle-relaxation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:muscle-relaxation":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,43,81],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":27,"conditions":28,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100495864","phase-2-effect-of-magnesium-sulphate-pretreatment-in-pediatric-abdominal-surgery-100495864",false,"NCT05736744","Effect of Magnesium Sulphate Pretreatment in Pediatric Abdominal Surgery","Effect of Magnesium Sulphate Pretreatment on the Onset and Duration of Intense and Deep Neuromuscular Block of Rocuronium Versus Cis-Atracurium in Pediatric Abdominal Surgery","MgSO4\u002FMR","Inclusion Criteria:\n\n1. Age group 2-12 years old\n2. Both genders\n3. Children who will be scheduled to undergo elective laparoscopic surgeries.\n4. Patients with American Society of Anesthesiologist physical status classification of 1 or 2-\n\nExclusion Criteria:\n\n1. Patients who are beyond the selected age group.\n2. Patients on medications that interfered with muscle activity.\n3. Allergy to medications used in this study.\n4. Neuro-muscular diseases.\n5. Renal or hepatic impairment.\n6. Hypermagnesemia (\\>2.5 mmol) or hypomagnesemia (\\\u003C1.7 mmol).\n7. Parental refusal to participate in the study","ALL","2 Years","12 Years",{"count":21,"type":22},58,"ESTIMATED","INTERVENTIONAL",[25,26],"PHASE2","PHASE3","In this study, the investigators will compare the effect of magnesium sulphate pretreatment on the onset and duration of intense and deep neuromuscular Block of rocuronium versus Cis-Atracurium and on the period of no response to nerve stimulation in children undergoing elective open abdominal surgeries.",[29],"Muscle Relaxation","RECRUITING","2025-01-17",{"date":33,"type":34},"2025-01-20","ACTUAL",{"date":36,"type":34},"2023-06-20",{"date":38,"type":22},"2025-12-01",{"name":40,"class":41},"Assiut University","OTHER",2,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":17,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":23,"phases":54,"briefSummary":56,"conditions":57,"keywords":64,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":78,"locationsCount":80},"100570460","the-potential-protective-effect-of-using-muscle-relaxants-during-electroporation-ablation-pfa-100570460","NCT06707532","The Potential Protective Effect of Using Muscle Relaxants During Electroporation Ablation (PFA)","The Use of Muscle Relaxants During Electroporation Ablation (PFA) as a Potential Protective Factor Against Damage to Transverse Striated Muscle Tissue and the Heart","Inclusion Criteria:\n\n* Patients with requirement for PFA ablation for cardiac indications and ability to provide informed consent for study participation\n\nExclusion Criteria:\n\n* Patients with allergies to the general anaesthetics used, genetic diseases of the neuromuscular plateau - e.g. Duchenne dystrophy, myasthenia gravis - and patients who do not gived informed consent to participate in the study will be excluded from the study.","18 Years","90 Years",{"count":53,"type":22},32,[55],"NA","The study aims to improve the safety of the electroporation ablation (PFA) procedure by using muscle relaxants to reduce skeletal muscle damage during the procedure. It will also assess myocardial damage to improve the procedure's quality and speed up recovery after the procedure.",[58,59,60,61,29,62,63],"Kidney Failure, Acute","Myopathy; Drugs","Heart Arrhythmia","Succinylcholine Sensitivity","General Anesthetic Drug Adverse Reaction","Projection",[65,66,67,68,69,70,71],"electroporation ablation (PFA)","muscle relaxants","rocuronium","chronic pain","acute kidney failure","chronic heart failure","drug protection","2024-11-26",{"date":74,"type":34},"2024-11-27",{"date":76,"type":34},"2024-08-01",{"date":38,"type":22},{"name":79,"class":41},"4th Military Clinical Hospital with Polyclinic, Poland",1,{"id":82,"slug":83,"hasResults":11,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":87,"eligibilityCriteria":88,"healthyVolunteers":11,"sex":17,"minAge":50,"maxAge":89,"enrollmentInfo":90,"targetDuration":4,"studyType":23,"phases":92,"briefSummary":93,"conditions":94,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":80},"100497496","phase-2-effect-of-mgso4-pretreatment-on-muscle-relaxation-100497496","NCT05757999","Effect of MgSO4 Pretreatment on Muscle Relaxation","Effect of Magnesium Sulphate Pretreatment on Cis-Atracurium Induced Neuromuscular Block and Recovery Characteristics: A Randomized Controlled Trial.","MgSO4\u002FCisA","Inclusion Criteria:\n\n* Age group 18-60 years old\n* Both genders\n* Patients who will be scheduled to undergo elective otorhinolaryngological surgery.\n* Patients with BMI between 18.5 and 24.9 Kg\u002Fm2.\n* Patients with American Society of Anesthesiologist physical status classification of 1 or 2\n\nExclusion Criteria:\n\n* Patients who are less than 18 years old or more than 60 years old.\n* Patients on medications that interfered with muscle activity.\n* Allergy to medications used in this study.\n* Pregnancy or suspected pregnancy.\n* Neuro-muscular diseases.\n* Renal or hepatic impairment.\n* Hypermagnesemia (\\>2.5 mmol) or hypomagnesemia (\\\u003C1.7 mmol).\n* Patients refusing to study","60 Years",{"count":91,"type":22},100,[25,26],"In this study, the effect of magnesium sulphate on the onset and duration of intense and moderate cis-atracurium induced neuromuscular blocking and on the period of no response to nerve stimulation will be evaluated in patients who will recieve magnesium sulphate (intervention group) and patients who will not recieve magnesium sulphate (comparator group).",[29],"2024-06-28",{"date":97,"type":34},"2024-07-01",{"date":99,"type":34},"2023-07-23",{"date":101,"type":22},"2025-05",{"name":40,"class":41}]