[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"muscle-tear\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:muscle-tear":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,46,88],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100578539","effects-of-high-intensity-laser-therapy-in-muscle-injuries-100578539",false,"NCT06812611","Effects of High Intensity Laser Therapy in Muscle Injuries","Effects of High Intensity Laser Therapy In Lower Limb Muscle Injuries: a Randomized Controlled Study","THEALinMJ","Inclusion Criteria:\n\n* presence of a grade III A muscle lesion of the lower limbs, according to the Mueller-Wohlfart classification, confirmed by ultrasound examination and occurred during sporting activity at least 5 days before inclusion in the study;\n* no previous muscle injury in the last 6 months;\n* signing of the written informed consent for participation in the study.\n\nExclusion Criteria:\n\n* previous muscle injuries or bone fractures of the lower limbs in the last 6 months;\n* knee instability due to previous rupture of the knee ligaments;\n\n  • instability or previous sprain of the ankle;\n* active neoplastic or infectious diseases;\n* contraindications to biostimulation;\n* congenital anomalies of the lower limbs.","ALL","16 Years",{"count":20,"type":21},24,"ESTIMATED","INTERVENTIONAL",[24],"NA","Muscle injuries are frequent traumatic events in daily life, particularly during sports. In sports, their incidence varies from 10% to 55% of total injuries. According to the Mueller Wohlfart classification, muscle injuries are classified into direct traumatic injuries (contusion-laceration) and indirect traumatic injuries, which are further divided into non-structural injuries (grade I and II) and structural injuries. Structural lesions are further divided into partial muscle lesions (grade III): 3 A, minor partial lesion, i.e. lesion of one or more primary bundles with a secondary bundle; 3 B, moderate partial lesion, i.e. lesion of at least one secondary bundle and with a rupture area \\\u003C 50% of the muscle surface; and (sub)total muscle injury (grade IV).",[27],"Muscle Tear",[29,30,31,32],"laser","high energy","limb","muscle tear","RECRUITING","2026-05-13",{"date":36,"type":37},"2026-05-14","ACTUAL",{"date":39,"type":37},"2025-12-01",{"date":41,"type":21},"2027-04-01",{"name":43,"class":44},"Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":17,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":4,"studyType":22,"phases":56,"briefSummary":57,"conditions":58,"keywords":63,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":45},"100596413","thermal-therapies-in-the-treatment-of-muscle-injuries-100596413","NCT07045129","Thermal Therapies in the Treatment of Muscle Injuries","Inclusion Criteria:\n\n* Participant reported a sudden event\n* Acute onset pain located on the posterior thigh\n* Clinical diagnosis of an acute muscle injury defined as:\n\nLocalized pain during palpation of the area, Increasing pain during isometric contraction, Localized pain during specific tests.\n\n* MRI confirmed acute muscle lesion grade 1 - 2 - 3 (Pollock et al., 2014) of hamstring muscles\n* Available for physiotherapy treatment 4-5 days a week\n* MRI of the injury performed in Aspetar within 7 days from the injury\n* Available for follow-up\n* Compliant with heat or cold-water immersion\n\nExclusion Criteria:\n\n* Chronic condition, diabetes, or immune compromised state\n* Neurological, cardiovascular, pulmonary, or muscular pathology\n* Pacemaker wearer\n* Metallic prosthesis\n* Skin infection\n* Under medication: anti-inflammatory treatment, pain killer drugs, fluoroquinolone antibiotics\n* Contraindication to MRI\n* Previous verified or suspected lower limb muscle injury for the same leg and the same muscle within the last 6 months\n* Chronic lower limb muscle problems on the same muscle\n* Grade 0 and 4 muscle injury determined by MRI (Pollock et al., 2014)\n* Do not have an intention to return to full sport activity\n* Do not want to receive one of the therapies \u002F Noncompliance with heat or cold therapies\n* Contraindication to heat\n* Do not want to comply with follow-up\n* Pregnancy","18 Years","40 Years",{"count":55,"type":21},135,[24],"Muscle strain injuries represent one of the most prevalent injuries in athletes. Despite this high injury prevalence, there is no evidence to support some of the currently used therapeutic strategies. Amongst them, thermal therapies and especially cryotherapy modalities (Ice, Cold water immersion, perfused garments) have been extensively used on soft tissue injuries to reduce pain perception and decrease inflammation. However, recent findings in humans and in animals have reported conflictual results on the effects of cold on muscle regeneration. On the other hand, recent studies in humans suggest that passive heat exposure can impact positively muscle protein synthesis, mitochondrial content and muscle torque in injured, immobilized and healthy participants. Furthermore, preliminary results from our group have shown a faster removal of muscle damages from the muscle and suggest a better muscle regeneration after a localized heat exposure. As such, our preliminary results confirmed that local heating may represent a promising tool to accelerate muscle regeneration. This randomized controlled trial will investigate the therapeutic effect of two thermal interventions (Hot or cold-water immersion) in the management of acute lower limbs muscle injuries. 135 patients will be distributed in a counterbalanced way into 3 groups: Hot, Cold and Control. All the groups will receive the same physiotherapy treatment. The thermal intervention will consist in 10 sessions of either, 60-minute hot water bath (42°C) for the hot group or, 15-minute Cold water bath (12°C) for the cold group realized after the 10 first physiotherapy session. All thermal interventions will be performed after the testing and physiotherapy treatment.",[59,60,61,62,27],"Hamstring Injuries","Hamstring Muscle Repair","Hamstring Muscles","Hamstring Rupture",[64,65,66,67,68,69,70,71,72,73,74,75,76,77,32],"muscle injury","muscle injuries","hamstring","muscle repair","regeneration","muscle recovery","thermal therapy","CWI","HWI","cold water immersion","hot water immersion","cryotherapy","heat therapy","HD EMG","NOT_YET_RECRUITING","2025-06-22",{"date":81,"type":37},"2025-07-01",{"date":83,"type":21},"2025-09",{"date":85,"type":21},"2028-09",{"name":87,"class":44},"Aspetar",{"id":89,"slug":90,"hasResults":11,"nctId":91,"briefTitle":92,"officialTitle":93,"acronym":94,"eligibilityCriteria":95,"healthyVolunteers":11,"sex":17,"minAge":53,"maxAge":96,"enrollmentInfo":97,"targetDuration":4,"studyType":22,"phases":99,"briefSummary":100,"conditions":101,"keywords":105,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":110,"lastUpdatePostDateStruct":111,"startDateStruct":113,"completionDateStruct":115,"leadSponsor":117,"locationsCount":45},"100455153","achilles-tendon-for-the-treatment-of-gluteus-medius-insufficiency-100455153","NCT05206838","Achilles Tendon for the Treatment of Gluteus Medius Insufficiency","Achilles Tendon Homograft for the Treatment of Gluteus Medius Insufficiency After Hip Replacement","HLS","Inclusion Criteria:\n\n* Persisting limping with positive Trendelenburg's sign for at least 12 months after total hip arthroplasty\n* Rupture\u002Favulsion of the gluteus medius tendon verified with ultrasound or MRI\n* Leg length discrepancy of less than 1 cm\n* Femoral offset discrepancy of less than 25%\n\nExclusion Criteria:\n\n* Neuromuscular disorders","80 Years",{"count":98,"type":21},44,[24],"Residual limping after total hip arthroplasty is a serious complication that lacks effective treatment. The purpose of this study is to evaluate a surgical treatment for residual limping and compare its results with non-surgical treatment. Our hypothesis is that surgical treatment followed by physiotherapy increases hip function and reduces limping compared with non-surgical treatment with physiotherapy alone.",[102,103,104,27],"Arthroplasty Complications","Muscle Weakness","Muscle Atrophy",[106,107,108,109],"Gluteus medius","Limp","Abductor","Trendelenburg","2025-04-05",{"date":112,"type":37},"2025-04-08",{"date":114,"type":37},"2022-06-29",{"date":116,"type":21},"2028-12",{"name":118,"class":44},"Sahlgrenska University Hospital"]