[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"musculoskeletal-health\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:musculoskeletal-health":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,47,75,109,165,196,232],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100644834","functional-muscle-bone-incongruity-index-fkui-a-prospective-observational-study-100644834",false,"NCT07677033","Functional Muscle-Bone Incongruity Index (FKUI): A Prospective Observational Study","Functional Muscle-Bone Incongruity Index (FKUI): Combined Evaluation of Handgrip Strength, Total Hip Bone Mineral Density, and Lumbar-Hip Bone Mineral Density Discordance in Adults Undergoing DXA","FKUI","Inclusion Criteria:\n\n* Age 18 years or older\n* Attendance at the Physical Medicine and Rehabilitation outpatient clinic\n* Scheduled to undergo routine bone mineral density assessment by DXA as part of clinical evaluation\n* Ability to perform handgrip strength testing\n* Availability of lumbar spine and total hip bone mineral density measurements suitable for analysis\n* Ability and willingness to provide written informed consent\n\nExclusion Criteria:\n\nExclusion Criteria:\n\n* Age younger than 18 years\n* Secondary causes of osteoporosis (e.g., hyperparathyroidism, Cushing syndrome, malignancy, or other conditions affecting bone metabolism)\n* History of metabolic bone disease\n* Major trauma or fracture within the previous 6 months\n* Upper extremity disorders that may significantly affect handgrip strength measurement (e.g., severe osteoarthritis, neurological disorders, major deformities)\n* DXA measurements that are technically inadequate or unsuitable for analysis\n* Refusal or inability to provide written informed consent","ALL","18 Years",{"count":20,"type":21},200,"ESTIMATED","OBSERVATIONAL","The Functional Muscle-Bone Incongruity Index (FKUI) is a novel approach developed to evaluate the relationship between muscle function and bone health. This prospective observational study aims to investigate the clinical applicability of FKUI, which combines handgrip strength, total hip bone mineral density (BMD), and lumbar-hip BMD discordance. Approximately 200 adult participants undergoing routine DXA assessment will be enrolled. The study will examine whether the combined evaluation of muscle function and bone health parameters provides a more comprehensive assessment of musculoskeletal status than individual measures alone.",[25,26,27,28],"Osteoporosis","Musculoskeletal Health","Sarcopenia","Osteopenia",[30,15,31,32,33],"Functional Muscle-Bone Incongruity Index FKUI","Bone Mineral Density","Hip-Spine Discordance","Handgrip Strength","RECRUITING","2026-06-24",{"date":37,"type":38},"2026-06-30","ACTUAL",{"date":40,"type":38},"2026-05-01",{"date":42,"type":21},"2027-05-01",{"name":44,"class":45},"Kanuni Sultan Suleyman Training and Research Hospital","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":54,"sex":17,"minAge":18,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":58,"conditions":59,"keywords":63,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":46},"100627798","physical-fitness-assessment-in-professional-and-amateur-e-sports-players-100627798","NCT07453316","Physical Fitness Assessment in Professional and Amateur E-Sports Players","Comparing the Physical Fitness Levels of Professional and Amateur E-Sports Players","Inclusion Criteria:\n\n* Adults aged 18 to 30 years\n* Able to read and understand Turkish\n* Professional e-sports players:\n* ≥25 hours per week of structured gaming\n* Affiliated with a competitive team or organization\n* Participates in official tournaments at least once per month\n* Receives income or sponsorship related to gaming\n\nAmateur e-sports players:\n\n* ≤15 hours per week of recreational gaming\n* Not affiliated with a professional team or league\n* Does not receive income or sponsorship from gaming\n* Voluntary agreement to participate and provide informed consent\n\nExclusion Criteria:\n\n* History of respiratory, cardiovascular, or neurological disorders\n* History of surgery within the last 6 months\n* Current use of medication that may affect physical performance\n* Currently undergoing physical therapy or rehabilitation\n* Any musculoskeletal injury that may impair performance during physical fitness testing.",true,"30 Years",{"count":57,"type":21},40,"The aim of this observational cross-sectional study is to compare the physical fitness characteristics of professional and amateur e-sports players and to determine whether differences exist between the two groups in terms of physical fitness parameters.",[60,26,61,62],"Physical Fitness","Sedentary Behavior","E-Athletes",[64],"E-Sports, Physical Fitness, Professional Gamers, Amateur Gamers, Sedentary Lifestyle, Musculoskeletal Health, Reaction Time, Balance, Aerobic Capacity","NOT_YET_RECRUITING","2026-03-02",{"date":68,"type":38},"2026-03-05",{"date":70,"type":21},"2026-03-09",{"date":72,"type":21},"2027-03-09",{"name":74,"class":45},"Istinye University",{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":79,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":54,"sex":81,"minAge":82,"maxAge":83,"enrollmentInfo":84,"targetDuration":4,"studyType":86,"phases":87,"briefSummary":89,"conditions":90,"keywords":94,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":46},"100626239","impact-of-supplementation-in-improving-metabolic-health-outcomes-ismos-study-100626239","NCT07433049","Impact of Supplementation in Improving Metabolic Health Outcomes (ISMOS) Study","Inclusion Criteria:\n\n* Women aged 40-60 years old\n* Chinese, Malay or Indian\n* BMI between 23.0-35.0 kg\u002Fm2\n* Proficient in English language\n* Willing to comply with study protocol \\& provide informed consent\n\nExclusion Criteria:\n\n* Pregnant or planning a pregnancy\n* Diagnosis with Diabetes, Polycystic Ovary Syndrome (PCOS), autoimmune diseases, chronic organ failure, severe heart disease, eating disorders and\u002For other medical conditions which in the PI's judgment which may affect study outcomes\n* Fasting glucose value ≥ 7.0 mmol\u002FL\n* Active cancer or treatment of cancer in the last 3 years\n* Participating in other nutritional intervention studies\n* Taking oral corticosteroids, anti-psychotic and\u002For weight loss drugs\n* Having planned hospitalization in the next 12 months\n* Planning to have major diet changes in the next 12 months\n* Taking a medically prescribed supplement(s) that contains 3 or more of the ingredients of the study product\n* Taking a non-prescribed supplement(s) that contains 3 or more of the ingredients of the study product in the last 1 month","FEMALE","40 Years","60 Years",{"count":85,"type":21},400,"INTERVENTIONAL",[88],"NA","This study investigates the role of multivitamin and multimineral (MVM) supplementation in improving metabolic, musculoskeletal, and mental health among midlife Asian women aged 40-60 years, a critical period marked by hormonal and physiological transitions from pre- to post-menopause. Evidence from the GUSTO cohort in Singapore has shown that higher plasma levels of vitamins B6, B9, B12, and D are associated with better metabolic profiles, insulin sensitivity, and mental wellbeing, while deficiencies are linked to increased metabolic and psychological risks. Given that vitamin insufficiency and central obesity are highly prevalent among Asian women even at lower BMI, this randomized, double-blind, placebo-controlled trial will evaluate whether 12 months of daily MVM supplementation can reduce MetaboAge and improve metabolic, mental, and muscle health outcomes compared with placebo. Findings will inform preventive strategies for extending health span and mitigating chronic disease risks among midlife women in Asia.",[91,92,26,93],"Glucose Control","Mental Health","Body Composition",[95,96,97,98,99],"Multivitamin and mineral supplementation","Women","Metabolic health","Mental health","Muscle health","2026-02-19",{"date":102,"type":38},"2026-02-25",{"date":104,"type":38},"2026-01-20",{"date":106,"type":21},"2028-01",{"name":108,"class":45},"Institute for Human Development and Potential (IHDP), Singapore",{"id":110,"slug":111,"hasResults":11,"nctId":112,"briefTitle":113,"officialTitle":113,"acronym":4,"eligibilityCriteria":114,"healthyVolunteers":54,"sex":17,"minAge":115,"maxAge":4,"enrollmentInfo":116,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":118,"conditions":119,"keywords":133,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":156,"lastUpdatePostDateStruct":157,"startDateStruct":159,"completionDateStruct":161,"leadSponsor":163,"locationsCount":4},"100609070","healthspan-connect-programme-of-research-100609070","NCT07209774","Healthspan Connect Programme of Research","Inclusion Criteria:\n\n* Age 12 years or older at time of enrollment.\n* Resident in the United Kingdom.\n* Able to participate in the study using digital tools (smartphone, tablet, or computer).\n* Able to provide informed consent (digital consent accepted).\n* For participants aged 12-15 years: must have parent\u002Fguardian consent in addition to their own assent.\n\nExclusion Criteria:\n\n* Individuals unable to provide informed consent (or parental consent where applicable).\n* Individuals not resident in the UK.\n* Individuals unable to complete study requirements due to lack of internet access, inability to use digital devices, or severe digital literacy barriers.","12 Years",{"count":117,"type":21},100000,"Healthspan Connect is a new research programme designed to understand what helps people stay healthy as they age. The programme will explore how lifestyle, environment, genetics, and social factors influence healthy ageing and overall wellbeing.\n\nThe programme will recruit participants aged 12 years and older across the UK. By including adolescents, the programme aims to understand how early life behaviours and experiences shape long-term health. There is no upper age limit, and people from all backgrounds are encouraged to participate. Special pathways ensure that young participants provide consent in an age-appropriate way.\n\nHealthspan Connect is a digital and home-based study, meaning participants can take part from home using smartphones, computers, and online surveys. Participants may also be asked to collect samples such as blood, saliva, stool, urine, or other biological specimens at home using easy-to-use kits. In some sub-studies, participants may be invited to attend research visits for additional tests, scans, or clinical assessments. Family members and close contacts may also be invited to participate in some studies.\n\nThrough Healthspan Connect, researchers aim to:\n\n* Identify the biological, environmental, and social factors that help people live longer, healthier lives.\n* Understand how different groups, including those historically underrepresented in research, experience ageing.\n* Explore ways to support behaviour changes that improve health over the lifespan.\n* Provide near real-time information to inform health policies and interventions.\n\nParticipants may also be asked for permission to link their information with health records, education records, and environmental data to better understand health outcomes over time.\n\nThis programme will serve as a flexible platform for multiple sub-studies, allowing participants to contribute to a wide range of research questions related to healthy ageing, resilience, and long-term health. All data and biological samples will be stored securely and used to advance scientific knowledge, with participant privacy carefully protected.",[120,92,121,122,123,124,125,126,127,128,26,129,130,131,132],"Cancer","Ageing Well","Resilience","Cognitive Health","Psychological Health","Environmental Health Effects","Cardiovascular Health","Metabolic Health","Neurological Health","Respiratory Health","Allergies","Eye Health","Other",[134,135,136,137,138,139,140,141,142,143,144,145,146,147,148,149,150,151,152,153,154,155],"Healthy ageing","Healthspan","Longevity","Ageing resilience","Life course determinants","Multiple long-term conditions","Digital health research","Remote monitoring","Mobile health (mHealth)","Wearables","Biobank","Biological specimen collection","Home-based sample collection","Epidemiology","Longitudinal cohort study","Adolescents and ageing","Underrepresented populations in research","Behaviour change","Environmental exposures","Data linkage","Electronic health records (EHR)","United Kingdom","2025-09-29",{"date":158,"type":38},"2025-10-07",{"date":160,"type":21},"2026-01-05",{"date":162,"type":21},"2056-01-05",{"name":164,"class":45},"King's College London",{"id":166,"slug":167,"hasResults":11,"nctId":168,"briefTitle":169,"officialTitle":170,"acronym":4,"eligibilityCriteria":171,"healthyVolunteers":54,"sex":17,"minAge":18,"maxAge":172,"enrollmentInfo":173,"targetDuration":4,"studyType":86,"phases":175,"briefSummary":176,"conditions":177,"keywords":180,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":187,"lastUpdatePostDateStruct":188,"startDateStruct":190,"completionDateStruct":192,"leadSponsor":194,"locationsCount":46},"100607703","immediate-effects-of-flossband-and-mobilization-with-movement-on-shoulder-mobility-in-volleyball-athletes-100607703","NCT07192003","Immediate Effects of Flossband and Mobilization With Movement on Shoulder Mobility in Volleyball Athletes","Comparison of the Immediate Effect of Flossband and Mobilization With Movement on Shoulder Mobility in Volleyball Athletes: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Age between 18 and 50 years.\n* Male or female volleyball athletes (indoor or beach), at amateur or professional level.\n* Regular training routine of at least two sessions per week.\n* No shoulder pain at the time of testing or during the previous three months.\n\nExclusion Criteria:\n\n* History of shoulder surgery, structural shoulder injuries (e.g., fractures, labrum tear), or recurrent glenohumeral dislocation.\n* Skin disorders contraindicating the intervention, including active dermatitis, inflammatory-phase psoriasis, cutaneous infections (e.g., folliculitis), open wounds, burns, eczema, or hypersensitivity in the shoulder region.\n* Vascular disorders contraindicating the intervention, including history or diagnosis of deep vein thrombosis, symptomatic varicose veins, peripheral arterial disease, lymphedema, or advanced chronic venous insufficiency.\n* Other conditions contraindicating intervention: peripheral neuropathies with significant sensory loss, presence of a pacemaker in the region of band application, known allergy to elastic band material, or pain during shoulder movement at assessment.\n* Development of shoulder or elbow injuries during the study, especially requiring surgical intervention.\n* Participants who voluntarily withdraw from the study at any time.","50 Years",{"count":174,"type":21},36,[88],"The goal of this clinical trial is to learn if Floss Band application works as effectively as mobilization with movement (MWM) to improve shoulder mobility in volleyball athletes. It will also explore whether these techniques affect athletes' perception of movement fluency and sport-specific performance.\n\nThe main questions it aims to answer are:\n\nDoes Floss Band application immediately improve shoulder range of motion in volleyball athletes? Does Floss Band application change the perception of movement fluency compared to MWM? Does Floss Band application impact sport-specific performance tests compared to MWM?\n\nParticipants will:\n\nBe randomly assigned to receive either Floss Band or mobilization with movement Have their shoulder mobility, perception of movement, and sport performance tested before and immediately after the intervention",[178,179,26],"Healthy Athlete","Shoulder Mobility",[181,182,183,184,185,186],"Range of Motion","Shoulder","Sports","Physical Therapy Modalities","Mobilization with Movement","Volleyball","2025-09-21",{"date":189,"type":38},"2025-09-25",{"date":191,"type":21},"2025-10-20",{"date":193,"type":21},"2026-04-18",{"name":195,"class":45},"Federal University of Paraíba",{"id":197,"slug":198,"hasResults":11,"nctId":199,"briefTitle":200,"officialTitle":201,"acronym":4,"eligibilityCriteria":202,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":203,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":205,"conditions":206,"keywords":211,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":224,"lastUpdatePostDateStruct":225,"startDateStruct":227,"completionDateStruct":228,"leadSponsor":230,"locationsCount":4},"100577662","the-weight-of-victory-exploring-short--and-long-term-health-outcomes-in-former-male--female-elite-athletes-from-weight-sensitive-sports-100577662","NCT06801210","The Weight of Victory: Exploring Short- and Long-term Health Outcomes in Former Male & Female Elite Athletes from Weight-sensitive Sports","The Weight of Victory: Exploring Short- and Long-term Health Outcomes in Former Male & Female Elite Atheltes from Weight-sensitive Sports","Inclusion Criteria:\n\n* Represented the national team at senior and\u002For junior level, (Non-organized sports) competed at national and\u002For international level. , \\>1 year since retirement , \\>18 years old,and a proficient level of Norwegian reading and writing skills\n\nExclusion Criteria:\n\n\\-",{"count":204,"type":21},1500,"The health of former elite athletes has been identified as a critical research gap where there is limited knowledge about both short- and long-term consequences after ending their careers. The transition phase from an active elite career to everyday life has been shown to be particularly problematic, yet this issue has been little studied among former Norwegian elite athletes. Furthermore, questions remain regarding the health of athletes from weight-sensitive sports, such as weight-class, aesthetic, and certain endurance sports. These athletes face specific challenges related to maintaining a certain physique and frequent changes in body weight during their active careers. This group has been shown to be vulnerable to a range of problematic health outcomes related to low energy availability, and little is known about the long-term effects of a career involving this.\n\nTherefore, the overall purpose of the project is to map the mental and physical health of former elite athletes. At the same time, there will be a particular focus on the differences between weight-sensitive and less weight-sensitive sports, different types of sports, gender, as well as previous dieting and eating behaviors.",[26,207,92,208,209,210],"Fertility","Quality of Life","Body Image","Disordered Eating",[212,98,213,214,215,216,217,218,219,207,220,221,222,223],"Elite athletes","Somatic health","Disordered eating","Musculoskeletal health","Quality of life","Anxiety and depression","Behavioral","Reproductive health","Harassment","Body acceptance","Personality traits","Weight regulation","2025-01-23",{"date":226,"type":38},"2025-01-30",{"date":226,"type":21},{"date":229,"type":21},"2025-06-30",{"name":231,"class":45},"Norwegian School of Sport Sciences",{"id":233,"slug":234,"hasResults":11,"nctId":235,"briefTitle":236,"officialTitle":237,"acronym":238,"eligibilityCriteria":239,"healthyVolunteers":54,"sex":17,"minAge":240,"maxAge":4,"enrollmentInfo":241,"targetDuration":4,"studyType":86,"phases":243,"briefSummary":244,"conditions":245,"keywords":252,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":260,"lastUpdatePostDateStruct":261,"startDateStruct":263,"completionDateStruct":265,"leadSponsor":267,"locationsCount":269},"100553627","stress-and-musculoskeletal-health-in-employees-100553627","NCT06488547","Stress and Musculoskeletal Health in Employees","Musculoskeletal Disorders and Stress Management, in Employees","MUStress","Inclusion Criteria:\n\n* Writing and reading greek.\n* Consent to provide their medical history.\n* Consent to be measured with electronic devices.\n\nExclusion Criteria:\n\n* Employees who are close to retirement (at least 2 years before) and those for whom any known factor may prevent them from completing the intervention (eg travel, transfer).\n* Pregnancy.\n* Pacemaker, history of seizures.\n* Diagnosed musculoskeletal injury.\n* Diagnosed diseases such as: osteoarthritis, autoimmune diseases (rheumatoid arthritis, lupus, etc.), stroke, myocardial infarction, malignant neoplasms, psychiatric disease, disability.\n* Systematic reception of cortisone and anti-inflammatory treatment, up to at least three months before the intervention.\n* Drugs or substances.\n* Participation in another interventional program of musculoskeletal rehabilitation, physical therapy, stress management or health promotion.","19 Years",{"count":242,"type":21},57,[88],"This study aims to evaluate potential correlation of stress as estimated by certain biological markers, namely saliva cortisol, Heart rate variability (HRV), Electromyography (EMG) with musculoskeletal system health status, and assess the impact of a stress management intervention..The intervention group will be trained to apply two evidence based stress management techniques and they will be guided with tips and advice about musculoskeletal health.\n\nImpact of the intervention upon measured stress related markers will be assessed.",[246,247,26,248,249,250,251],"Musculoskeletal Diseases or Conditions","Musculoskeletal Pain","Stress","Work Related Stress","Occupation-related Stress Disorder","Medically Unexplained Symptoms",[253,254,255,256,257,258,259],"stress management","stress biomarkers","musculoskeletal health","work-related","biofeedback","saliva cortisol","HRV","2024-06-27",{"date":262,"type":38},"2024-07-05",{"date":264,"type":38},"2024-06-01",{"date":266,"type":21},"2026-12-31",{"name":268,"class":45},"University of Thessaly",2]