[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"music-therapy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:music-therapy":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,19,0,[8,44,75,102,140,164,192,220,247,274,299,322,352,377,400,424,455,476,505],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":4},"100645352","relational-music-therapy-procedural-support-for-paediatric-patients-and-families-facing-repeated-invasive-procedures-100645352",false,"NCT07680348","Relational Music Therapy Procedural Support for Paediatric Patients and Families Facing Repeated Invasive Procedures","Relational Regulation: A Relational Approach to Music Therapy-based Procedural Support for Paediatric Patients and Families Facing Repeated Invasive Procedures","Inclusion Criteria:\n\n* Paediatric patient (ages 5-12) undergoing recurring needle procedures (venipuncture, intravenous (IV) cannulation, subcutaneous injections, intramuscular (IM) injections, Port-a-Cath, lumbar punctures, and bone marrow transplant, aspiration or biopsy)\n* Parents or caregiver of a paediatric patient (ages 5-12) undergoing recurring needle procedures.\n* Willing to participate in music therapy-based sessions.\n* Able to complete brief questionnaires and\u002For take part in an interview.\n* Paediatric inpatient, outpatient, or palliative care unit.\n\nExclusion Criteria:\n\n* Patients currently under heavy sedation or anaesthetic medication that impairs consciousness during data collection.\n* Medically unstable or emergency care patients where participation may interfere with clinical care.\n* Non-English or non-Norwegian speakers where language barriers may pose difficulties in participants understanding study information, and issues in interpretation and analysis of collected data.\n* Patients with severe cognitive or developmental impairment making meaningful engagement with the intervention difficult.\n* Severe behavioural\u002Fpsychiatric conditions that will make safe participation difficult or impossible.","ALL","5 Years","12 Years",{"count":20,"type":21},20,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study explores how personalised music therapy can support children and their parents during repeated medical procedures, such as blood tests or injections. Many children find these procedures painful or frightening, and repeated experiences can lead to high anxiety and difficulty coping. Parents often feel distressed as well, which can affect how well they are able to support their child. Because children and parents regulate each other emotionally, helping both members of the pair is important for reducing distress.\n\nThis study aims to explore how personalised music therapy-based procedural support (MTPS) influences the relational and emotional processes that help children and their parents cope, regulate, and build resilience during repeated medical procedures.",[27,28,29,30,31],"Paediatric","Invasive Procedure","Relation, Family","Music Therapy","Procedural Fear","NOT_YET_RECRUITING","2026-06-25",{"date":35,"type":36},"2026-07-02","ACTUAL",{"date":38,"type":21},"2026-09",{"date":40,"type":21},"2027-01",{"name":42,"class":43},"Anglia Ruskin University","OTHER",{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":51,"sex":16,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":4,"studyType":22,"phases":55,"briefSummary":56,"conditions":57,"keywords":60,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":74},"100641992","effects-of-music-therapy-in-chronic-neck-pain-100641992","NCT07658729","Effects of Music Therapy in Chronic Neck Pain","The Effects of Music Therapy on Pain, Cervical Position Sense, and Balance in Individuals With Chronic Neck Pain","Inclusion Criteria:\n\n* Being between 20-50 years old\n* Having experienced neck pain for at least 3 months\n* Having a resting neck pain score of 3 or higher on the Numeric Pain Scale\n* Being willing to participate in the study\n\nExclusion Criteria:\n\n* Patients with surgical indications for and\u002For who have undergone surgery in the cervical region\n* Having received physiotherapy and\u002For other treatment for neck pain within the last year\n* Those with a history of trauma and systemic disease in the cervical region (malignant condition, systemic rheumatic disease, etc.)\n* Having additional musculoskeletal diseases that may also affect the cervical region (thoracic outlet and scoliosis, etc.)\n* Having a psychiatric illness\n* Being visually impaired",true,"20 Years","50 Years",{"count":5,"type":21},[24],"This study aims to investigate the effects of music therapy on pain, cervical position sense, and balance in individuals with chronic neck pain. Chronic neck pain is a common musculoskeletal disorder that may impair proprioception and postural control, negatively affecting daily functioning and quality of life. Music therapy is a safe, low-cost, and non-pharmacological intervention with potential benefits for pain management and sensorimotor function; however, evidence regarding its effects in musculoskeletal rehabilitation is limited. In this study, nineteen individuals with chronic neck pain will listen to instrumental Turkish Classical Music in the Nihavend mode for 60 minutes. Pain intensity, cervical position sense, and static and dynamic balance will be assessed before and after the intervention. The findings are expected to provide evidence for the clinical use of music therapy as an adjunctive treatment in chronic neck pain rehabilitation.",[58,59,30],"Neck Pain","Pain",[61,62,63,64],"neck pain","music therapy","proprioception","balance","2026-06-18",{"date":67,"type":36},"2026-06-23",{"date":69,"type":21},"2026-07-01",{"date":71,"type":21},"2026-08-30",{"name":73,"class":43},"Karabuk University",1,{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":4,"eligibilityCriteria":81,"healthyVolunteers":11,"sex":16,"minAge":82,"maxAge":4,"enrollmentInfo":83,"targetDuration":4,"studyType":22,"phases":85,"briefSummary":86,"conditions":87,"keywords":92,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":4},"100612366","music-therapy-to-reduce-anxiety-and-pain-in-chronic-pain-patients-during-procedures-100612366","NCT07252648","Music Therapy to Reduce Anxiety and Pain in Chronic Pain Patients During Procedures","Effect of Peri-Operative Music Therapy on Anxiety, Pain Catastrophising, and Pain in Chronic Pain Patients Undergoing Interventional Pain Procedures - A Randomised Controlled Trial","Inclusion Criteria:\n\n* aged ≥21years\n* chronic pain ≥3 months\n* scheduled for interventional pain procedures\n\nExclusion Criteria:\n\n* presence of hearing impairment\n* lack of capacity to consent\n* non-interventional pain procedures, e.g. lignocaine infusion, ketamine infusion\n* pregnant women","21 Years",{"count":84,"type":21},110,[24],"This study aims to find out whether listening to music before, during, and after pain procedures can help reduce anxiety, pain catastrophising, and acute pain in patients with chronic pain. Music therapy may provide a simple, safe, and non-drug way to help patients relax and feel more comfortable.\n\nIn this study, adult patients with chronic pain who are scheduled for interventional pain procedures at Singapore General Hospital will be randomly assigned to one of two groups. One group will listen to self-selected music through headphones and speakers before, during, and after the procedure. The other group will receive standard care without music.\n\nResearchers will measure anxiety, pain catastrophising, and pain levels before and after the procedure using validated questionnaires. The main outcome will be the level of anxiety after the procedure. Other outcomes include pain catastrophising scores, pain scores during local anaesthetic injection, and overall patient satisfaction.\n\nThis study will help determine if music therapy can be routinely used to improve comfort and emotional well-being for patients undergoing interventional pain procedures.",[88,89,30,90,91],"Chronic Pain","Anxiety","Pain Perception","Pain Catastrophizing",[91,30,89,88],"2026-04-23",{"date":95,"type":36},"2026-04-29",{"date":97,"type":21},"2026-03-30",{"date":99,"type":21},"2026-12-31",{"name":101,"class":43},"Singapore General Hospital",{"id":103,"slug":104,"hasResults":11,"nctId":105,"briefTitle":106,"officialTitle":107,"acronym":4,"eligibilityCriteria":108,"healthyVolunteers":51,"sex":16,"minAge":109,"maxAge":4,"enrollmentInfo":110,"targetDuration":4,"studyType":22,"phases":112,"briefSummary":113,"conditions":114,"keywords":117,"overallStatus":130,"whyStopped":4,"lastUpdateSubmitDate":131,"lastUpdatePostDateStruct":132,"startDateStruct":134,"completionDateStruct":136,"leadSponsor":138,"locationsCount":74},"100623612","use-of-augmented-reality-glasses-and-noise-cancelling-headphones-to-reduce-dental-anxiety-in-adult-patients-100623612","NCT07398898","Use of Augmented Reality Glasses and Noise-Cancelling Headphones to Reduce Dental Anxiety in Adult Patients","Use of New Technologies in Dentistry","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Qualified for one of the following dental procedures: supragingival scaling, curettage, tooth extraction, or caries cavity preparation and restoration\n* Provided written informed consent\n* Agreed to random allocation to one of the study groups\n* Able to understand and complete the STAI questionnaire and VAS pain scale\n\nExclusion Criteria:\n\n* Acute dental pain at the time of the procedure\n* Teeth qualified for resection\n* Pregnancy\n* Diagnosis of cerebral palsy\n* Epilepsy with seizures in the past 6 months\n* Use of hearing aids\n* Severe vision impairment\n* Non-cooperative behavior or inability to understand the study questionnaires\n* Absence on the scheduled procedure date","18 Years",{"count":111,"type":21},250,[24],"This study investigates whether new audiovisual technologies can help reduce anxiety and stress experienced by adult patients during dental procedures. Dental fear and anxiety are common barriers to receiving proper oral care. This randomized controlled trial aims to explore whether the use of specific devices-augmented reality (AR) glasses and noise-cancelling (ANC) headphones-can improve patient comfort and decrease physiological signs of stress during dental treatment.\n\nParticipants in this study will undergo a standard dental procedure. In addition, they will be randomly assigned to one of three groups: a control group (no audiovisual intervention), a group using ANC headphones that play relaxing music during the procedure, or a group using AR glasses that display relaxing visual scenes along with the same music.\n\nBefore the procedure, each participant will complete a psychological questionnaire (STAI) to assess their level of anxiety. During the procedure, physiological stress will be monitored using sensors that track parameters such as skin conductance (GSR) and heart rate. After the treatment, patients will be asked to rate their pain level and describe their experience with or without the audiovisual intervention.\n\nThe goal is to better understand the effectiveness of non-pharmacological methods in reducing anxiety and stress in adult dental patients. Participation in the study is entirely voluntary and will not affect the quality or availability of dental care. Patients may withdraw at any time without consequences. The study also collects basic demographic information and patient feedback to evaluate potential factors that may influence anxiety levels.\n\nBy testing new immersive tools such as AR glasses and ANC headphones in a real clinical setting, this research may contribute to improving patient well-being and enhancing the dental care experience.",[115,30,116],"Dental Anxiety","Oral Surgical Procedures",[118,119,120,121,122,123,124,125,126,127,128,129],"dental anxiety","Music therapy","augmented reality","active noise cancelling","maxillofacial surgery","Dental phobia","audiovisual distraction","dental fear","perioperative anxiety","STAI","galvanic skin response","relaxation techniques","RECRUITING","2026-03-25",{"date":133,"type":36},"2026-03-27",{"date":135,"type":36},"2026-03-01",{"date":137,"type":21},"2026-06-30",{"name":139,"class":43},"Medical University of Warsaw",{"id":141,"slug":142,"hasResults":11,"nctId":143,"briefTitle":144,"officialTitle":145,"acronym":4,"eligibilityCriteria":146,"healthyVolunteers":51,"sex":16,"minAge":109,"maxAge":147,"enrollmentInfo":148,"targetDuration":4,"studyType":22,"phases":150,"briefSummary":151,"conditions":152,"keywords":153,"overallStatus":130,"whyStopped":4,"lastUpdateSubmitDate":155,"lastUpdatePostDateStruct":156,"startDateStruct":158,"completionDateStruct":160,"leadSponsor":162,"locationsCount":74},"100485560","music-as-a-complement-to-pharmacological-sedation-in-ventilator-treated-icu-patients-100485560","NCT05602662","Music as a Complement to Pharmacological Sedation in Ventilator Treated ICU Patients.","Music as a Complement to Pharmacological Sedation in Ventilator Treated ICU Patients - Prospective Randomized Cross-over Study.","Inclusion Criteria: In the ICU, entilator treated adults \\> 18 years.\n\n\\-\n\nExclusion Criteria:\n\n* Children \\>18 years.\n* Deaf people.\n* Children \\\u003C18 Years","100 Years",{"count":149,"type":21},100,[24],"Can music theraphy during mechanical ventilation in the ICU, decrease the need of pharmacological sedation? Included patients will listen to music selected by a music therapist via headphones two times one hour during two days. Effects on heart rate, blood pressure, respiratory rate and dosing of pharmacological sedation will be observed. 100 patients will be included and radomized equally to earphones with and without music.",[30],[154],"Music therapy, Ventilator treated patients, Need of sedation.","2026-02-10",{"date":157,"type":36},"2026-02-12",{"date":159,"type":36},"2022-04-01",{"date":161,"type":21},"2027-12-31",{"name":163,"class":43},"Karlstad Central Hospital",{"id":165,"slug":166,"hasResults":11,"nctId":167,"briefTitle":168,"officialTitle":169,"acronym":4,"eligibilityCriteria":170,"healthyVolunteers":11,"sex":16,"minAge":109,"maxAge":4,"enrollmentInfo":171,"targetDuration":4,"studyType":22,"phases":173,"briefSummary":174,"conditions":175,"keywords":179,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":183,"lastUpdatePostDateStruct":184,"startDateStruct":186,"completionDateStruct":188,"leadSponsor":190,"locationsCount":74},"100619458","effects-of-music-on-procedural-pain-in-distal-radius-fracture-reduction-100619458","NCT07344883","Effects of Music on Procedural Pain in Distal Radius Fracture Reduction","Effects of Music on Pain in Orthopedic Patients With Distal Radius Fractures Undergoing Non-surgical Reduction: a Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients of both sexes, 18 years of age or older\n* Patients with distal radius fracture requiring non-surgical (closed) reduction\n* Able to provide informed consent\n\nExclusion Criteria:\n\n* Patients with severe hearing impairment\n* Patients diagnosed with cognitive or psychiatric disorders\n* Patients requiring emergency\u002Furgent intervention\n* Open fractures (exposed fractures)",{"count":172,"type":21},192,[24],"This randomized controlled trial (RCT) evaluates the effectiveness of music as a complementary intervention for pain control during non-surgical reduction of distal radius fractures in orthopedic patients. Distal radius fractures are among the most common traumatic injuries presenting to emergency departments and are frequently associated with intense procedural pain and significant physiological stress responses. Despite standard pharmacological analgesia, optimal pain management during fracture reduction remains a clinical challenge, and evidence regarding non-pharmacological adjuncts in the emergency orthopedic setting is still limited The study will enroll 192 adult patients admitted to the orthopedic emergency departments of AUSL Piacenza and AOU Parma with distal radius fractures requiring closed reduction. Participants will be randomly assigned (1:1:1) to one of three groups: a 20-minute session of patient-preferred music, a 20-minute session of standardized music selected by a music therapist, or standard care without music. Pain intensity will be assessed using the Numerical Rating Scale (NRS), while physiological stress will be evaluated through heart rate and blood pressure measurements, collected at baseline (T0) and 20 minutes later (T1), immediately after the reduction procedure The trial is designed as a prospective, randomized, controlled study with blinded data analysis, and all data will be collected and managed in compliance with current privacy and data protection regulations. By generating robust evidence on a low-cost, safe, and easily implementable intervention, the PolSound trial aims to improve procedural pain management and patient experience in emergency orthopedic care, potentially supporting the integration of music-based interventions into standard analgesic protocols.",[59,176,177,30,178],"Blood Pressure","Heart Rate","Nursing",[180,181,182],"nursing","musictherapy","pain","2026-01-08",{"date":185,"type":36},"2026-01-15",{"date":187,"type":21},"2026-02",{"date":189,"type":21},"2027-02",{"name":191,"class":43},"Azienda Unita Sanitaria Locale di Piacenza",{"id":193,"slug":194,"hasResults":11,"nctId":195,"briefTitle":196,"officialTitle":196,"acronym":197,"eligibilityCriteria":198,"healthyVolunteers":11,"sex":16,"minAge":109,"maxAge":4,"enrollmentInfo":199,"targetDuration":4,"studyType":22,"phases":201,"briefSummary":202,"conditions":203,"keywords":206,"overallStatus":130,"whyStopped":4,"lastUpdateSubmitDate":211,"lastUpdatePostDateStruct":212,"startDateStruct":214,"completionDateStruct":216,"leadSponsor":218,"locationsCount":74},"100609687","stepped-care-intervention-of-music-and-imagery-to-assess-relief-scimitar-trial-100609687","NCT07217821","Stepped-Care Intervention of Music and Imagery to Assess Relief (SCIMITAR) Trial","SCIMITAR","Inclusion Criteria:\n\n* musculoskeletal pain in the low back, cervical spine, or extremities (hips, knees, or shoulders) for ≥ 3 months\n* at least moderate pain severity, defined as a PEG score ≥ 4 on a 0 (no pain) to 10 (worst pain)\n* access to computer, tablet, or smartphone\n* ability to pass a technology assessment\n\nExclusion Criteria:\n\n* Past month hospitalization for medical or psychiatric illness\n* housing insecurity\n* suicidal ideation with current intent\u002Fplan\n* hearing or cognitive impairment that may interfere with music listening or abstract thinking needed for imagery work\n* currently receiving music therapy services",{"count":200,"type":21},180,[24],"Th Stepped-Care Intervention of Music and Imagery to Assess Relief (SCIMITAR) Trial. SCIMITAR builds on our pilot study, the Feasibility and Acceptability of Music Imagery and Listening Interventions for Analgesia (FAMILIA), which demonstrated that telehealth delivery of music listening (ML) and music imagery (MI) interventions is feasible and acceptable to Veterans with chronic musculoskeletal pain. SCIMITAR leverages what we learned from FAMILIA into a fully powered trial, harnessing the benefits of sequential ML and MI into a stepped-care, music therapy intervention via telehealth for Veterans needing relief from pain.",[204,205,30],"Chronic Musculoskeletal Pain","Veterans",[207,208,209,62,210],"chronic pain","veterans","musculoskeletal pain","clinical trial","2025-10-15",{"date":213,"type":36},"2025-10-16",{"date":215,"type":36},"2023-08-30",{"date":217,"type":21},"2026-04-30",{"name":219,"class":43},"Henry M. Jackson Foundation for the Advancement of Military Medicine",{"id":221,"slug":222,"hasResults":11,"nctId":223,"briefTitle":224,"officialTitle":225,"acronym":4,"eligibilityCriteria":226,"healthyVolunteers":11,"sex":16,"minAge":227,"maxAge":228,"enrollmentInfo":229,"targetDuration":4,"studyType":22,"phases":231,"briefSummary":232,"conditions":233,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":238,"lastUpdatePostDateStruct":239,"startDateStruct":241,"completionDateStruct":243,"leadSponsor":245,"locationsCount":74},"100589196","music-therapy-during-hypothermia-in-the-nicu-100589196","NCT06951269","Music Therapy During Hypothermia in the NICU","The Effect of Music Therapy on Pain Levels in Neonates With Hypoxic-ischemic Encephalopathy During Hypothermia: a Randomized Pilot and Feasibility Study","Inclusion Criteria:\n\n\\- Neonates diagnosed with neonatal hypoxic ischemic encephalopathy who have undergone hypothermic therapy as part of their medical treatment.\n\nExclusion Criteria:\n\n* Newborns with a gestational age of less than 35 weeks and a birth weight of less than 1800 grams.\n* Newborns in palliative care or with congenital anomalies with a poor prognosis will also be excluded, as will those with preexisting neurological or genetic conditions.\n* Furthermore, newborns with a history of serious medical complications that may influence participation in the study, such as pulmonary hypertension or secondary seizure syndrome, will be considered ineligible.\n* Finally, patients with an N-PASS score of less than -2 will be excluded.","35 Weeks","44 Weeks",{"count":230,"type":21},22,[24],"Background: Hypoxic-ischemic encephalopathy (HIE) is a neurological condition caused by poor oxygenation during the peripartum period. The main strategy to mitigate neurological damage is hypothermic therapy (HT), whose effectiveness-among other factors-depends on adequate pain management. Considering the prevalence of allodynia in this group of patients, routine nursing procedures can become sources of additional stress and pain. Music therapy is used in this population to promote self-regulation and relaxation, and may therefore help reduce pain levels after routine nursing procedures.\n\nResearch question: What is the effect of an entrainment-based live music therapy intervention on pain levels in newborns with hypoxic-ischemic encephalopathy undergoing hypothermic therapy after routine nursing procedures? Methodology: A randomized, crossover pilot and feasibility study. Participants will be 22 newborns admitted to the Neonatal Intensive Care Unit (NICU) of the University Hospital Fundación Santa Fe de Bogotá. Participants will receive standard care plus a 15-minute live music therapy session after a routine nursing procedure, or standard care alone. The primary outcome is the Premature Infant Pain Profile-Revised (PIPP-R) scale, which will be assessed through video recordings. Secondary outcomes are vital signs, heart rate variability, and electroencephalography (EEG) recordings.\n\nExpected outcomes: Through this study, the aim is to improve the comfort and well-being of patients with HIE during TH. In addition, the safety and feasibility of music therapy in this population will be evaluated, seeking to contribute to current knowledge about the mechanisms of music therapy.",[30,59,234,235,236,237],"Allodynia","Neonates","NICU","Hypothermia Neonatal","2025-09-17",{"date":240,"type":36},"2025-09-23",{"date":242,"type":21},"2025-10-30",{"date":244,"type":21},"2027-08-01",{"name":246,"class":43},"Fundación Santa Fe de Bogota",{"id":248,"slug":249,"hasResults":11,"nctId":250,"briefTitle":251,"officialTitle":252,"acronym":4,"eligibilityCriteria":253,"healthyVolunteers":11,"sex":16,"minAge":109,"maxAge":4,"enrollmentInfo":254,"targetDuration":4,"studyType":22,"phases":256,"briefSummary":257,"conditions":258,"keywords":261,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":266,"lastUpdatePostDateStruct":267,"startDateStruct":269,"completionDateStruct":271,"leadSponsor":273,"locationsCount":4},"100593595","effects-of-music-on-preoperative-anxiety-in-patients-with-femoral-fractures-undergoing-surgery-100593595","NCT07008482","Effects of Music on Preoperative Anxiety in Patients With Femoral Fractures Undergoing Surgery","Effects of Music on Preoperative Anxiety in Patients With Femoral Fractures Scheduled for Surgical Intervention: A Randomized Controlled Study","Inclusion Criteria:\n\n* Patients of both sexes, 18 years of age or older\n* Patients with femur fracture who are candidates for surgery\n* Able to provide informed consent.\n\nExclusion Criteria:\n\n* Patients with a diagnosis of hearing loss\n* Patients diagnosed with cognitive or psychiatric disorders\n* Patients undergoing emergency\u002Femergency surgery",{"count":255,"type":21},154,[24],"This randomized controlled trial (RCT) investigates the effectiveness of music therapy in reducing preoperative anxiety among elderly patients with femoral fractures. Preoperative anxiety is known to worsen physiological stability, increase pain perception, and negatively impact recovery, yet specific evidence on non-pharmacological interventions like music therapy in the orthogeriatric setting is lacking.\n\nThe study will enroll 154 adult patients admitted to the Orthogeriatrics Unit for elective femoral fracture surgery. Participants will be randomly assigned to receive either a 20-minute session of music therapy or standard care. Anxiety will be measured using the APAIS scale, and pain will be assessed with the NRS scale, both before and after the intervention.\n\nThe trial is designed as a blinded, prospective RCT, with data collected and managed under current privacy regulations. By generating robust data on this low-cost, safe intervention, the study aims to improve preoperative management and patient outcomes in orthopedic surgical care.",[89,59,259,260,30],"Surgery","Femoral Fractures",[262,263,264,265],"NURSING","MUSICTHERAPY","ANXIETY","PAIN","2025-08-11",{"date":268,"type":36},"2025-08-12",{"date":270,"type":21},"2025-09",{"date":272,"type":21},"2026-07",{"name":191,"class":43},{"id":275,"slug":276,"hasResults":11,"nctId":277,"briefTitle":278,"officialTitle":279,"acronym":280,"eligibilityCriteria":281,"healthyVolunteers":11,"sex":16,"minAge":109,"maxAge":282,"enrollmentInfo":283,"targetDuration":4,"studyType":22,"phases":285,"briefSummary":286,"conditions":287,"keywords":288,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":266,"lastUpdatePostDateStruct":291,"startDateStruct":293,"completionDateStruct":295,"leadSponsor":297,"locationsCount":4},"100374443","effect-of-music-therapy-on-postoperative-health-outcomes-100374443","NCT04155528","Effect of Music Therapy on Postoperative Health Outcomes","The Effect of Music Therapy on Acute Pain and Sleep Quality Among Patients Underwent Abdominal Surgery: A Randomized Control Trial","MToPOHO","Inclusion Criteria:\n\nPatients who will meet the following criteria will be eligible to participate in this study:\n\n* Adult patients, including both sexes and aged between18-60 years.\n* Had an abdominal surgery.\n* Give informed consent and are hemodynamically stabilized.\n* Willing to receive music therapy for three consecutive postoperative days by using Headset.\n\nExclusion Criteria:\n\n* Patients will be ineligible to participate in this study if they have any of the following:\n\n  * Hearing deficit.\n  * History of chronic pain.\n  * Metastasis cancer, on narcotic medication.\n  * Dementia, or psychiatric diagnosis","60 Years",{"count":284,"type":21},60,[24],"Patients underwent surgical procedure experiences acute postoperative pain, but less than half report adequate postoperative pain relief. The poor management of pain after surgery is associated with inadequate sleep and poor mood. Music therapy is described as a non-pharmacological technique to accomplish individualized patient's goals for hospital treatment. Music has been used as a healing approach. In Saudi Arabia, there is a lack of evidence related to the effect of music therapy on pain and sleep among patients who underwent abdominal surgery. Studies are needed to address additional aspects of pain management and the promotion of sleep among Saudi adult postoperative people by using non-pharmacological modalities.",[30],[119,59,289,290],"Sleep quality","Abdominal surgery",{"date":292,"type":36},"2025-08-14",{"date":294,"type":21},"2027-12-01",{"date":296,"type":21},"2028-12-30",{"name":298,"class":43},"Cairo University",{"id":300,"slug":301,"hasResults":11,"nctId":302,"briefTitle":303,"officialTitle":304,"acronym":4,"eligibilityCriteria":305,"healthyVolunteers":51,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":306,"targetDuration":4,"studyType":22,"phases":308,"briefSummary":309,"conditions":310,"keywords":4,"overallStatus":130,"whyStopped":4,"lastUpdateSubmitDate":315,"lastUpdatePostDateStruct":316,"startDateStruct":317,"completionDateStruct":319,"leadSponsor":321,"locationsCount":74},"100588286","music-therapy-and-humanization-in-ed-healthcare-professionals-100588286","NCT06939426","Music Therapy and Humanization in ED Healthcare Professionals","Impact of a Short Music Therapy Program on Intra- and Interpersonal Factors of Humanized Care in a Group of Emergency Nursing Staff at the University Hospital Fundación Santa Fe de Bogotá: a Mixed-methods Pilot and Feasibility Study","Inclusion Criteria:\n\n* Be a member of the emergency department nursing staff at the FSFB for a minimum of 6 months.\n* Be able to commit to participating in eight music therapy sessions over a four-week period.\n* Have the minimum reading skills to understand the questionnaires\n\nExclusion Criteria:\n\n\\- Staff with untreated mental health disorders.",{"count":307,"type":21},25,[24],"Background: Healthcare professionals in emergency departments frequently experience stressful situations that could jeopardize their mental health, sense of purpose, and ability to empathize with patients, families, and colleagues.\n\nResearch question: What is the impact of a short music therapy program on the intra- and interpersonal factors of humanized care among emergency nursing staff at the University Hospital Fundación Santa Fe de Bogotá (FSFB)? Methodology: This research is a mixed-methods pilot and feasibility study. For the quantitative component, we will apply the HUMAS (Healthcare Professional Humanization Scale) and ProQOL (Professional Quality of Life) measure at the start and at the end of the music therapy program. For the qualitative component, focus group interviews will be conducted and analyzed via thematic analysis.\n\nDiscussion: This study seeks to support the nursing staff of the FSFB emergency department through an interactive, creative, and participatory music therapy self-care program focused on one of the most important pillars of the institution: the humanization of care.",[311,312,313,30,314],"Stress","Burnout","Quality of Life (QOL)","Humanization of Care","2025-08-07",{"date":268,"type":36},{"date":318,"type":36},"2025-06-12",{"date":320,"type":21},"2026-05-01",{"name":246,"class":43},{"id":323,"slug":324,"hasResults":11,"nctId":325,"briefTitle":326,"officialTitle":327,"acronym":4,"eligibilityCriteria":328,"healthyVolunteers":51,"sex":329,"minAge":109,"maxAge":330,"enrollmentInfo":331,"targetDuration":4,"studyType":22,"phases":333,"briefSummary":334,"conditions":335,"keywords":339,"overallStatus":130,"whyStopped":4,"lastUpdateSubmitDate":343,"lastUpdatePostDateStruct":344,"startDateStruct":346,"completionDateStruct":348,"leadSponsor":350,"locationsCount":74},"100597918","effect-of-music-and-warm-foot-bath-therapy-on-pregnancy-related-anxiety-blood-pressure-and-quality-of-life-100597918","NCT07064733","Effect of Music and Warm Foot Bath Therapy on Pregnancy-Related Anxiety, Blood Pressure and Quality of Life","A Randomized Controlled Trial on the Effect of Music Therapy and Warm Foot Bath Therapy on Anxiety, Blood Pressure, and Quality of Life in Low-Risk Primigravida Pregnant Women","Inclusion Criteria:\n\n* 18-39 years of age,\n\n  * Literate; able to make an informed decision to participate, communicate verbally, and sign a consent form\n  * Pregnant with a single, live fetus\n  * Have a smartphone\n  * Low-risk primigravida pregnant with a gestational age of 26 weeks or more\n\nExclusion Criteria:\n\n* \\- Having hearing impairment,\n* Refusing to participate,\n* Being illiterate,\n* Having communication problems,\n* Being hospitalized with severe preeclampsia,\n* The newborn not surviving.\n* Antepartum hemorrhage\n* Preeclampsia,\n* Gestational hypertension,\n* Cervical insufficiency,\n* Having pregnancy-related complications such as congenital fetal anomalies and intrauterine growth restriction diagnosed before 28 weeks of gestation or having multiple pregnancies;\n* Having psychiatric disorders (known anxiety or depression, other illnesses),\n* Having medical problems such as endocrine disorders (gestational diabetes mellitus, thyroid dysfunction, etc.);\n* Having assisted reproductive techniques (ART) such as in vitro fertilization, embryo transfer, or\n* Pregnant women at risk of preterm birth will not be included in the study.","FEMALE","39 Years",{"count":332,"type":21},144,[24],"Study Title:\n\nThe Effects of Music Therapy and Warm Foot Bath on Pregnancy-Related Stress, Blood Pressure, and Quality of Life in Low-Risk Primigravida Women\n\nBrief Summary:\n\nThis randomized controlled trial investigates the impact of music therapy and warm foot bath therapy on pregnancy-related anxiety, blood pressure levels, and quality of life in low-risk primigravida pregnant women. Participants will be randomly assigned into four groups: music therapy, warm foot bath therapy, combined therapy, and control group. The interventions will be carried out for 2 weeks with pre- and post-assessments of anxiety and quality of life.",[336,30,337,338,89],"Primigravida Women","Blood Pressure Monitoring","Quality of Life",[340,62,341,338,342],"primigravida","Warm Foot Bath","blood pressure","2025-07-11",{"date":345,"type":36},"2025-07-15",{"date":347,"type":36},"2025-06-06",{"date":349,"type":21},"2026-04-01",{"name":351,"class":43},"Kırklareli University",{"id":353,"slug":354,"hasResults":11,"nctId":355,"briefTitle":356,"officialTitle":357,"acronym":4,"eligibilityCriteria":358,"healthyVolunteers":51,"sex":16,"minAge":359,"maxAge":4,"enrollmentInfo":360,"targetDuration":4,"studyType":22,"phases":362,"briefSummary":363,"conditions":364,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":368,"lastUpdatePostDateStruct":369,"startDateStruct":371,"completionDateStruct":373,"leadSponsor":375,"locationsCount":4},"100591429","comparing-music-supported-and-traditional-aerobic-training-in-geriatric-health-outcomes-100591429","NCT06980311","Comparing Music-Supported and Traditional Aerobic Training in Geriatric Health Outcomes","Comparison of the Effects of Music Therapy-Based Aerobic Exercise and Traditional Aerobic Exercise Training on Cardiopulmonary Functions, Functional Capacity, Balance, Peripheral Muscle Strength, Cognitive Functions, Depression, and Quality of Life in Geriatrics","Inclusion Criteria:\n\n* Being 65 years of age or older\n* Willingness to participate in the study\n\nExclusion Criteria:\n\n* Presence of uncontrolled hypertension (≥180\u002F110 mmHg) or severe complications of diabetes (e.g., diabetic neuropathy, proliferative retinopathy, uncontrolled hypoglycemic episodes)\n* Presence of respiratory diseases such as Chronic Obstructive Pulmonary Disease (COPD), asthma, etc.\n* Presence of chronic neurological disorders such as Multiple Sclerosis (MS), Parkinson's Disease, Amyotrophic Lateral Sclerosis (ALS), etc.\n* Diagnosis of any oncological disease\n* Presence of acute musculoskeletal conditions that would prevent participation in exercise (e.g., fracture, advanced osteoarthritis, severe musculoskeletal injuries)\n* Having undergone any surgical operation within the past 6 months\n* Presence of visual or auditory impairments that could interfere with the assessment procedures\n* A score of ≤24 on the Mini-Mental State Examination (MMSE), indicating cognitive impairment\n* Participation in a regular exercise program within the last six months","65 Years",{"count":361,"type":21},33,[24],"The aim of this study is to comparatively evaluate the effects of a music therapy-based aerobic exercise program and traditional aerobic exercise training on cardiopulmonary functions, functional capacity, balance, peripheral muscle strength, cognitive functions, depression level and quality of life in geriatric individuals.",[365,366,30,367],"Geriatric","Aerobic Exercise","Physiotherapy and Rehabilitation","2025-05-17",{"date":370,"type":36},"2025-05-20",{"date":372,"type":21},"2025-06-01",{"date":374,"type":21},"2027-06-01",{"name":376,"class":43},"Bezmialem Vakif University",{"id":378,"slug":379,"hasResults":11,"nctId":380,"briefTitle":381,"officialTitle":382,"acronym":4,"eligibilityCriteria":383,"healthyVolunteers":51,"sex":329,"minAge":109,"maxAge":384,"enrollmentInfo":385,"targetDuration":4,"studyType":22,"phases":387,"briefSummary":388,"conditions":389,"keywords":4,"overallStatus":130,"whyStopped":4,"lastUpdateSubmitDate":391,"lastUpdatePostDateStruct":392,"startDateStruct":394,"completionDateStruct":396,"leadSponsor":398,"locationsCount":74},"100590669","therapy-on-perioperative-anxiety-and-pain-in-patients-100590669","NCT06970431","Therapy on Perioperative Anxiety and Pain in Patients","Effects of Preoperative Education Combined With Intraoperative Music Therapy on Perioperative Anxiety and Pain in Elective Cesarean Section Patients","Inclusion Criteria： ASA grade I or II, aged 18-40 years female must be singleton pregnancy eligible\n\nExclusion Criteria:\n\nHistory of pregnancy-related complications severe pregnancy complications (e.g., preeclampsia, gestational diabetes mellitus) Severe mental illness","40 Years",{"count":386,"type":21},300,[24],"This study aims to explore the effects of preoperative education combined with intraoperative music therapy on perioperative anxiety and pain in patients undergoing elective cesarean section. The study subjects were patients scheduled for cesarean section under combined spinal - epidural anesthesia. A prospective study design with random grouping was adopted. Through systematic preoperative education and intraoperative music intervention, multi - dimensional evaluations were carried out to analyze the effects of preoperative education combined with intraoperative music therapy on the relief of perioperative anxiety, pain and shivering in patients, as well as its impact on postoperative recovery and nursing satisfaction.",[30,89,390],"Health Education","2025-05-09",{"date":393,"type":36},"2025-05-14",{"date":395,"type":36},"2025-02-01",{"date":397,"type":21},"2026-01-10",{"name":399,"class":43},"Maternal and Child Health Hospital of Hubei Province",{"id":401,"slug":402,"hasResults":11,"nctId":403,"briefTitle":404,"officialTitle":404,"acronym":4,"eligibilityCriteria":405,"healthyVolunteers":51,"sex":16,"minAge":109,"maxAge":4,"enrollmentInfo":406,"targetDuration":4,"studyType":22,"phases":408,"briefSummary":409,"conditions":410,"keywords":412,"overallStatus":130,"whyStopped":4,"lastUpdateSubmitDate":415,"lastUpdatePostDateStruct":416,"startDateStruct":418,"completionDateStruct":420,"leadSponsor":422,"locationsCount":74},"100577578","the-effect-of-music-on-anxiety-and-vasospasm-in-patients-undergoing-transradial-angiography-100577578","NCT06800118","The Effect of Music on Anxiety and Vasospasm in Patients Undergoing Transradial Angiography","Inclusion Criteria:\n\n* Indication for radial coronary angiography (CA) due to non-acute coronary syndrome (ACS) reasons\n* Undergoing coronary angiography for the first time\n* Aged 18 years or older\n* Conscious, oriented, and cooperative\n* Able to read and understand Turkish\n* Willing to participate in the study\n* Without any physical limitations preventing music listening\n* Without a diagnosis of hearing loss\n* Not using a hearing aid\n* Without a diagnosis of anxiety disorder\n* Without any mental health disorders\n* Having signed the \"Voluntary Informed Consent Form.\n\nExclusion Criteria:\n\n* Indication for radial coronary angiography (CA) due to acute coronary syndrome (ACS)\n* Previous history of coronary angiography\n* Under the age of 18,\n* Unconscious, disoriented, or uncooperative,\n* Unable to read or understand Turkish,\n* Unwilling to participate in the study,\n* Having physical limitations that prevent listening to music,\n* Diagnosed with hearing loss,\n* Using a hearing aid,\n* Diagnosed with an anxiety disorder or taking medication for anxiety,\n* Having a mental health disorder,\n* Not signing the \"Voluntary Informed Consent Form.\"",{"count":407,"type":21},90,[24],"Cardiovascular diseases are among the most significant health issues threatening human well-being, representing the leading cause of mortality and morbidity worldwide and in our country among non-communicable diseases. In Turkey, 33.4% of deaths are attributed to circulatory system diseases and ischemic heart diseases, with coronary artery disease (CAD) being the most common cause. The most frequently applied and accurate invasive diagnostic method for diagnosing CAD is coronary angiography.\n\nCoronary angiography, still regarded as the gold standard today, is a diagnostic procedure that visualizes the heart's blood vessels using contrast media. This procedure can be performed via the femoral, brachial, radial, or axillary arteries. In the past, coronary interventional procedures were commonly performed through the femoral artery. However, following the 2017 European Society of Cardiology (ESC) guidelines on ST-segment elevation myocardial infarction (STEMI) management, the radial artery has become the preferred route due to its lower risk of bleeding and shorter hospital stays. Coronary angiography is performed in a sterile environment while the patient is awake.\n\nDue to its invasive nature and the involvement of a vital organ, coronary angiography can evoke anxiety and fear of death in patients. Factors contributing to this include uncertainty about the procedure, unfamiliarity with the environment, communication with unknown personnel, exposure to medical terminology, and unusual sounds in the procedure room.\n\nThe radial artery is more prone to vasospasm than other vessels used in coronary angiography, due to its smaller diameter and rich smooth muscle content. Local anesthesia is administered at the access site to reduce pain during radial artery interventions. Additionally, anticoagulant and vasodilatory drugs are used to prevent procedure-related vasospasms and thrombotic events. Despite these preventive measures, vasospasm is observed in 4-20% of patients undergoing transradial coronary angiography.\n\nAnxiety experienced by patients during the procedure can also contribute to vasospasm in the radial artery. Various invasive and non-invasive interventions, such as listening to music, acupressure, and massage, are frequently employed to reduce patient anxiety. Among these non-invasive methods, providing music during the procedure has gained prominence. Music helps divert patients' attention, enabling them to distance themselves from pain, fear, stress, and anxiety.",[411,89,30],"Radial Artery Spasm",[413,414,62],"Radial artery spasm","anxiety","2025-01-29",{"date":417,"type":36},"2025-01-31",{"date":419,"type":36},"2024-10-10",{"date":421,"type":21},"2025-04-20",{"name":423,"class":43},"Mersin University",{"id":425,"slug":426,"hasResults":11,"nctId":427,"briefTitle":428,"officialTitle":429,"acronym":4,"eligibilityCriteria":430,"healthyVolunteers":11,"sex":16,"minAge":431,"maxAge":432,"enrollmentInfo":433,"targetDuration":4,"studyType":22,"phases":434,"briefSummary":435,"conditions":436,"keywords":441,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":446,"lastUpdatePostDateStruct":447,"startDateStruct":449,"completionDateStruct":451,"leadSponsor":453,"locationsCount":74},"100576842","music-effect-on-the-self-injection-testing-fear-and-pain-100576842","NCT06790550","Music Effect on the Self-Injection, Testing Fear and Pain","Examination of Music's Demonstration to Self-Injection, Fear of Testing and Pain in Patients With Type 2 Diabetes","Inclusion Criteria:\n\n* Type 2 diabetes for at least one year\n* Self-administering insulin injection\n* Self-administering glucometer, insulin pen or insulin pump\n\nExclusion Criteria:\n\n* poor mental health\n* Having gestational diabetes mellitus or Type 1 diabetes\n* no hearing problems","15 Years","75 Years",{"count":149,"type":21},[24],"Diabetes is a chronic and broad-spectrum metabolic disorder characterized by hyperglycemia that occurs due to relative or absolute insulin deficiency or \"insulin resistance\" developed against insulin action in peripheral tissues, affecting many organs and causing multisystem involvement. Metabolic function continues to deteriorate after diagnosis, leading to worsening glycemic control and insulin therapy becoming necessary. However, patients may have difficulty adhering to insulin therapy. Fears about injections are common in both adults and children and, as research shows, are a major reason why people with diabetes avoid taking insulin. Addressing these fears is an important part of helping patients reduce their risk of diabetes-related complications. Helping patients manage their replacement pain may help reduce the effects of needle fear in the future. There are a number of strategies that can ease the pain.The use of music in pain management has advantages such as being reliable, cheap, and having no side effects, as well as reducing postoperative pain reports. Music distracts the individual from negative stimuli and allows them to focus on something they enjoy, thus reducing pain and anxiety. Music therapy has also been shown to have sedative-protective effects and reduce stress hormone levels. Listening to preferred music can distract and reduce the pain and negative emotions associated with an unpleasant experience.",[437,438,439,59,440,30],"Type 2 Diabetes Mellitus (T2DM)","Insulin","Fear","Injection",[442,438,443,182,444,445],"type 2 diabetes mellitus","fear","insulin injection","music","2025-01-24",{"date":448,"type":36},"2025-01-28",{"date":450,"type":21},"2025-01-30",{"date":452,"type":21},"2025-07-30",{"name":454,"class":43},"Dicle University",{"id":456,"slug":457,"hasResults":11,"nctId":458,"briefTitle":459,"officialTitle":459,"acronym":4,"eligibilityCriteria":460,"healthyVolunteers":11,"sex":16,"minAge":109,"maxAge":4,"enrollmentInfo":461,"targetDuration":4,"studyType":22,"phases":462,"briefSummary":463,"conditions":464,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":467,"lastUpdatePostDateStruct":468,"startDateStruct":470,"completionDateStruct":472,"leadSponsor":474,"locationsCount":74},"100575933","implementing-music-therapy-for-video-assisted-thoracoscopic-surgery-patients-a-quality-improvement-initiative-100575933","NCT06778720","Implementing Music Therapy for Video-Assisted Thoracoscopic Surgery Patients: A Quality Improvement Initiative","Inclusion Criteria:\n\n* Adults aged 18 years and older with lung mass diagnosis undergoing VATS\n\nExclusion Criteria:\n\n* Individuals with dementia, neurocognitive disorders, or chronic pain conditions.",{"count":20,"type":21},[24],"The purpose of this project is to introduce and implement music therapy as an evidence-based pain management protocol focused on reducing postoperative pain levels among Video-Assisted Thoracoscopic Surgery (VATS) patients in the Post-Anesthesia Care Unit (PACU) of the project site. The clinical question guiding this initiative is: In adult patients undergoing a VATS procedure, does the implementation of music therapy lead to lower postoperative pain scores in the PACU compared to no intervention within an 8-week timeframe? The investigator will ask eligible patients their immediate pain scores upon arrival into the PACU and then start music of patient's choice via over-the-ear headphones. Pain scores will be rechecked 30 minutes after implementation of music therapy. The standard of care pain medications and\u002For usual care will not be withheld or altered after surgery in lieu of music therapy.",[465,466,30],"Pain Assessment","VATS","2025-01-12",{"date":469,"type":36},"2025-01-16",{"date":471,"type":21},"2025-01-14",{"date":473,"type":21},"2025-03-10",{"name":475,"class":43},"Cedars-Sinai Medical Center",{"id":477,"slug":478,"hasResults":11,"nctId":479,"briefTitle":480,"officialTitle":481,"acronym":482,"eligibilityCriteria":483,"healthyVolunteers":11,"sex":329,"minAge":109,"maxAge":484,"enrollmentInfo":485,"targetDuration":4,"studyType":22,"phases":486,"briefSummary":487,"conditions":488,"keywords":490,"overallStatus":130,"whyStopped":4,"lastUpdateSubmitDate":497,"lastUpdatePostDateStruct":498,"startDateStruct":500,"completionDateStruct":502,"leadSponsor":503,"locationsCount":74},"100507906","physiological-and-psychological-effects-of-music-therapy-in-the-pregnant-woman-and-fetus-100507906","NCT05893485","Physiological and Psychological Effects of Music Therapy in the Pregnant Woman and Fetus","Physiological and Psychological Effects of Music Therapy in the Pregnant Woman and Fetus, WOMB (Women on Musical Bedrest)","WOMB","Inclusion Criteria:\n\n1. Pregnant women between 18 and 64 years of age.\n2. Singleton pregnancy.\n3. Hospital admission due to a high risk of premature delivery.\n4. Confirmed diagnosis of preterm premature rupture of membranes.\n5. Length of stay in the hospital for 48 hours or more and stable for 48 hours or more.\n6. Patients willing to listen to music.\n7. Patients willing to participate throughout all the music therapy sessions and the postpartum follow-up visit.\n\nExclusion Criteria:\n\n1. Hospital length of stay of less than 48 hours.\n2. Non-singleton pregnancy Gravidae with severe medical and or surgical complications during their hospital admission that prevents them from participating in Music Therapy sessions.","64 Years",{"count":284,"type":21},[24],"To evaluate the effects of music therapy in the care of antepartum mothers admitted for long-term hospitalization due to the high-risk status of their pregnancy. The investigators speculate that mothers who receive music therapy will be more successful in forming positive coping habits, bonding with their infant, and increasing the length of incubation during their pregnancy.\n\nFurthermore, there is no research that correlates music therapy applied to stress reduction, increased coping, and increased caregiver-infant bonding prior to birth within one protocol. However, there is a significant amount of research supporting music therapy efficacy with neonatal intensive care unit infants and caregiver bonding post-partum as well as improved physiological signs of stress in infants in the post-partum period.",[30,489],"Preterm Premature Rupture of Membrane (PPROM)",[119,491,492,493,494,495,496,89,311],"Antepartum","Preterm Premature Rupture of Membranes (PPROM)","Fetus","Woman","Post Traumatic Stress Disorder","Postpartum Depression","2024-09-11",{"date":499,"type":36},"2024-09-19",{"date":501,"type":36},"2023-05-15",{"date":135,"type":21},{"name":504,"class":43},"Christina Chianis Reed",{"id":506,"slug":507,"hasResults":11,"nctId":508,"briefTitle":509,"officialTitle":510,"acronym":4,"eligibilityCriteria":511,"healthyVolunteers":11,"sex":16,"minAge":109,"maxAge":282,"enrollmentInfo":512,"targetDuration":4,"studyType":22,"phases":514,"briefSummary":515,"conditions":516,"keywords":524,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":530,"lastUpdatePostDateStruct":531,"startDateStruct":533,"completionDateStruct":535,"leadSponsor":537,"locationsCount":4},"100471348","efficacy-of-transcutaneous-vagus-nerve-stimulation-paired-with-tailor-made-notched-music-therapy-versus-tailor-made-notched-music-training-for-chronic-subjective-tinnitus-100471348","NCT05417711","Efficacy of Transcutaneous Vagus Nerve Stimulation Paired With Tailor-Made Notched Music Therapy Versus Tailor-made Notched Music Training for Chronic Subjective Tinnitus","Efficacy of Transcutaneous Vagus Nerve Stimulation Paired With Tailor-Made Notched Music Therapy Versus Tailor-made Notched Music Training for Chronic Subjective Tinnitus: A Multicenter, Randomized, Double-blind, Controlled Clinical Trial","Inclusion Criteria:\n\n* Patients with tinnitus as the main complaint: the patients subjectively feel the sound in the ear or deep part of the head without internal or external sound stimulation, and therefore seek medical treatment\n* Chronic (≥ 6 months) and tonal tinnitus\n* Age 18-60\n* Tinnitus frequency is 125-8000 Hz\n* Hearing threshold at each frequency shall not exceed 70 dB HL\n\nExclusion Criteria:\n\n* Patients with conductive deafness, history of middle ear surgery, pulsatile tinnitus caused by vascular distortion and tinnitus caused by Meniere disease\n* History of head trauma, central nervous system diseases, mental diseases and drug abuse",{"count":513,"type":21},388,[24],"This clinical study is a prospective, multicenter, randomized, controlled, double-blind clinical study. Sun Yat Sen Memorial Hospital of Sun Yat sen University was the central unit, and Nanjing First Hospital, Sun Yat Sen people's Hospital, Guanfzhou Panyu central Hospital and Zhuhai integrated traditional Chinese and Western medicine hospital were the cooperative units. In this study, 388 patients with chronic subjective tinnitus were recruited. In view of chronic subjective tinnitus, a common ear disease, the study gave the patients three months of treatment with transcutaneous vagus nerve stimulation paired with tailor-made notched music therapy or tailor-made notched music training alone. By comparing the changes of subjective scale scores related to tinnitus before and after treatment in patients receiving two different therapies, such as THI, VAS, BAI, BDI, PSQI, to evaluate the efficacy of the two therapies, so as to judge whether transcutaneous vagus nerve stimulation paired with tailor-made notched music therapy is better than tailor-made notched music training alone. In addition, the study will continue to follow up the patients after the treatment for one year to observe the difference in the long-term sustained efficacy of the two therapies. This clinical study will also evaluate the two therapies from the perspective of compliance and safety, and explore the factors that affect the efficacy of the two therapies.",[517,518,30,519,520,521,522,523],"Tinnitus, Subjective","Vagus Nerve Stimulation","Double-Blind Method","Female","Male","Humans","Treatment Outcome",[525,526,527,528,529],"Chronic subjective tinnitus","Tailor-made notched music training","Vagus nerve stimulation","Electroencephalogram","Clinical trial","2023-11-22",{"date":532,"type":36},"2023-11-27",{"date":534,"type":21},"2023-11-23",{"date":536,"type":21},"2026-09-01",{"name":538,"class":43},"Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University"]