[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"muskuloskeletal-diseases\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:muskuloskeletal-diseases":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,50],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":32,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100643195","virtual-reality-based-rehabilitation-for-traumatic-hand-and-wrist-injuries-100643195",false,"NCT07633769","Virtual Reality-based Rehabilitation for Traumatic Hand and Wrist Injuries","Use of Virtual Reality to Improve Sensorimotor Function in Patients With Traumatic Wrist and Hand Injuries","AOT-VR-HAND","Inclusion Criteria:\n\n* Adults aged 18 years or older.\n* Diagnosis of a traumatic wrist and\u002For hand injury.\n* Referred for rehabilitation treatment at the participating hand therapy unit.\n* Ability to understand study procedures and provide written informed consent.\n* Ability to participate in the virtual reality intervention.\n\nExclusion Criteria:\n\n* Previous injury affecting the same hand.\n* Associated upper-limb conditions, including tenosynovitis or Dupuytren's disease.\n* Previous surgery involving the affected hand before the current traumatic injury.\n* Corticosteroid or other therapeutic injection in the affected hand within the previous 3 weeks.\n* Any physical, neurological, visual, vestibular, or medical condition that prevents safe use of the virtual reality device.\n* Inability to comply with the study procedures or assessments.","ALL","18 Years","75 Years",{"count":21,"type":22},40,"ESTIMATED","INTERVENTIONAL",[25],"NA","This randomized controlled trial aims to evaluate the effectiveness of immersive virtual reality (VR)-based Action Observation Therapy (AOT) as an adjunct to conventional rehabilitation in patients with traumatic wrist and hand injuries. Participants will receive standard rehabilitation treatment, and the intervention group will additionally undergo a six-week VR program involving observation and execution of functional hand and wrist movements. Outcomes related to hand function, grip strength, pain, proprioception, disability, and psychological factors will be assessed to determine the potential benefits of incorporating VR into rehabilitation programs.",[28,29,30,31],"Wrist Injury","Hand and Upper Limb Trauma","Hand and Forearm Trauma","Muskuloskeletal Diseases",[33,34,35,36],"Virtual Reality","Upper limb rehabilitation","Sensorimotor Function","Functional recovery","RECRUITING","2026-06-02",{"date":40,"type":41},"2026-06-08","ACTUAL",{"date":43,"type":41},"2026-02-01",{"date":45,"type":22},"2026-12-31",{"name":47,"class":48},"University of Malaga","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":17,"minAge":56,"maxAge":4,"enrollmentInfo":57,"targetDuration":4,"studyType":59,"phases":4,"briefSummary":60,"conditions":61,"keywords":67,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":49},"100614362","the-rheumsafer-study-improving-medication-appropriateness-in-people-with-rheumatic-conditions-100614362","NCT07278609","The RheumSafer Study: Improving Medication Appropriateness in People With Rheumatic Conditions","Inclusion Criteria:\n\n* Aged ≥60\n* Followed by a rheumatologist at MUHC for an inflammatory arthritis (such as rheumatoid arthritis, psoriatic arthritis, spondyloarthritis), a systemic autoimmune rheumatic disease (such as systemic lupus erythematosus, inflammatory myositis, systemic sclerosis, antiphospholipid antibody syndrome, Sjogren syndrome, systemic vasculitis), or another chronic musculoskeletal or rheumatic condition (such as crystal arthritis and osteoarthritis)\n* Currently taking ≥5 regular medications and ≥1 PIM\n* Anticipated ongoing clinical follow-up in rheumatology at an interval of every 3-9 months\n\nExclusion Criteria:\n\n* Unable to provide informed consent\n* Acute life-threatening illness or life expectancy \\\u003C12 months","60 Years",{"count":58,"type":22},100,"OBSERVATIONAL","The goal of this prospective observational quality improvement study is to determine if a physician tool, MedSafer, combined with educational brochures for patients, can help to reduce the use of 'potentially inappropriate medications' (PIMs) in adults aged 60 and over with rheumatic conditions and polypharmacy (taking 5 or more regular medications).\n\nResearchers will follow participants during usual rheumatic disease care. They will compare the rate of PIM deprescribing (stopping medications or reducing the dose) before and after the introduction of the following interventions:\n\n* MedSafer reports provided to treating physicians\n* EMPOWER consumer brochures provided to participants\n\nParticipants will complete 4 study visits over 18-20 months during which researchers will collect information on medication changes, serious adverse events (emergency visits or hospitalizations), and quality of life.",[62,63,64,65,31,66],"Rheumatic Diseases","Inflammatory Arthritis","Systemic Lupus Erthematosus (SLE)","Vasculitis","Systemic Autoimmune Diseases",[68,69,62,70],"Deprescribing","Potentially inappropriate medications","Polypharmacy","2026-04-27",{"date":73,"type":41},"2026-05-01",{"date":75,"type":41},"2025-10-29",{"date":77,"type":22},"2028-06-30",{"name":79,"class":48},"McGill University Health Centre\u002FResearch Institute of the McGill University Health Centre"]